European Commission approves Johnson & Johnson’s AKEEGA for BRCA1/2-mutated mHSPC

Reuters

Mar 10

European Commission approves Johnson & Johnson’s AKEEGA for BRCA1/2-mutated mHSPC

The European Commission approved an expanded indication for AKEEGA (niraparib and abiraterone acetate) with prednisone or prednisolone plus androgen deprivation therapy for patients with BRCA1/2-mutated metastatic hormone-sensitive prostate cancer. The decision was supported by Phase 3 AMPLITUDE data showing a 48% reduction in the risk of radiographic progression or death in BRCA1/2-mutated patients. In this subgroup, the overall survival analysis favored the regimen with a 20% lower risk of death.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Johnson & Johnson published the original content used to generate this news brief on March 09, 2026, and is solely responsible for the information contained therein.

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Johnson &amp; Johnson published the original content used to generate this news brief on March 09, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4007","symbol_name":"制药","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260309:nNDLch08XD:1","article_id":"2618673253","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2618673253","pubTimestamp":1773075968,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"The European Commission approved an expanded indication for AKEEGA  with prednisone or prednisolone plus androgen deprivation therapy for patients with BRCA1/2-mutated metastatic hormone-sensitive prostate cancer. 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The decision was supported by Phase 3 AMPLITUDE data showing a 48% reduction in the risk of radiographic progression or death in BRCA1/2-mutated patients. In this subgroup, the overall survival analysis favored the regimen with a 20% lower risk of death.\n      \n\n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Johnson & Johnson published the original content used to generate this news brief on March 09, 2026, and is solely responsible for the information contained therein.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"productRelease","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":true,"code":"91000000","status":"200"}}}