Neurogene full yr net loss widens on higher R&D costs

Reuters
Yesterday
Neurogene full yr net loss widens on higher R&D costs

Overview

  • US biotech reported full yr net loss widened, driven by higher Rett syndrome trial costs

  • Company ended yr with $269 mln in cash and investments, funding runway through Q1 2028

  • NGN-401 gene therapy program achieved full enrollment in Embolden trial, received FDA Breakthrough designation

Outlook

  • Company expects to complete dosing in Embolden trial in Q2 2026

  • Neurogene plans to present updated interim safety and efficacy data mid-2026

  • Company to initiate Process Performance Qualification campaign in mid-2026

Result Drivers

  • RETT SYNDROME TRIAL COSTS - Higher R&D expenses were mainly due to increased clinical trial costs and employee-related expenses for the Rett syndrome program

  • HIGHER G&A EXPENSES - General and administrative costs rose due to increased non-cash stock-based compensation and headcount

Company press release: ID:nBwbLNyhSa

Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

FY Net Income

-$90.35 mln

FY Operating Expenses

$103.33 mln

FY Operating Income

-$103.33 mln

Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 8 "strong buy" or "buy", no "hold" and no "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Neurogene Inc is $60.00, about 209.9% above its March 23 closing price of $19.36

For questions concerning the data in this report, contact Estimates.Support@lseg.com. For any other questions or feedback, contact reuters.support@thomsonreuters.com.

(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)

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