March 25 (Reuters) - Wall Street's main indexes rose on Wednesday as prospects of a de-escalation in the Middle East conflict allayed some fears around prolonged energy supply disruptions and lifted investor sentiment. .N

At 1330 EDT, the Dow Jones Industrial Average .DJI was up 0.81% at 46,495.96. The S&P 500 .SPX was up 0.76% at 6,605.99, and the Nasdaq Composite .IXIC was up 1.01% at 21,981.68.

The top three S&P 500 .PG.INX percentage gainers:

** EchoStar Corp SATS.OQ, up 9.7%

** Intel Corp INTC.OQ, up 7.8%

** Hewlett Packard Enterprise Co HPE.N, up 7.5%

The top three S&P 500 .PL.INX percentage losers:

** Verisk Analytics Inc VRSK.OQ, down 5.2%

** Generac Holdings Inc GNRC.N, down 4.9%

** Sandisk Corp SNDK.OQ, down 4.5%

The top three NYSE .PG.N percentage gainers:

** Solo Brands Inc SBDS.N, up 21.5%

** CNFinance Holdings Ltd CNF.N, up 15.1%

** Chewy Inc CHWY.N, up 14.8%

The top three NYSE .PL.N percentage losers:

** FiscalNote Holdings Inc NOTE.N, down 20.2%

** Alight Inc ALIT.N, down 18.2%

** Traeger Inc COOK.N, down 12.2%

The top three Nasdaq .PG.O percentage gainers:

** urban-gro Inc UGRO.OQ, up 102.0%

** Real Messenger Corp RMSG.OQ, up 101.6%

** iTonic Holdings Ltd ITOC.OQ, up 43.3%

The top three Nasdaq .PL.O percentage losers:

** Trugolf Holdings Inc TRUG.OQ, down 35.0%

** Anavex Life Sciences Corp AVXL.OQ, down 32.8%

** Maze Therapeutics Inc MAZE.OQ, down 32.0%

** Arm Holdings PLC ARM.O:BUZZ - Jumps on upbeat revenue projections from new AI chip nL4N40D0NE

** JPMorgan Chase & Co JPM.N:BUZZ - Ups Lanxess as pricing power improves amid APAC supply disruptions nL8N40D0KR

** Destiny Tech100 Inc DXYZ.N:BUZZ - Rises on report of SpaceX IPO plans nL4N40D0QP

** Nanobiotix SA NBTX.O:BUZZ - Jumps after media report says J&J mulls potential takeover nL8N40D0PO

** Sidus Space Inc SIDU.O:

** Rocket Lab Corp RKLB.O:

** AST SpaceMobile Inc ASTS.O:

** Satellogic Inc SATL.O:BUZZ - Space stocks rise after report of SpaceX IPO plans nL6N40D0LL

** DraftKings Inc DKNG.O:BUZZ - No longer faces acute short squeeze risk, S3 Research says nL6N40D0LF

** Alexandria Real Estate Equities Inc ARE.N:BUZZ - Falls after BMO cuts to 'market perform' nL4N40D0V9

** Newmont Corp NEM.N:

** Harmony Gold Mining Co Ltd HMY.N:

** Gold Fields Ltd GFI.N:

** Sibanye Stillwater Ltd SBSW.N:

BUZZ - Gold miners gain as oil price drop eases inflation, high rate concerns nL4N40D0W1

** Exxon Mobil Corp XOM.N:

** Chevron Corp CVX.N:

** Occidental Petroleum Corp OXY.N:

** Devon Energy Corp DVN.N:

BUZZ - Energy stocks dip as crude slides on Middle East ceasefire prospects nL4N40D0VA

** Terns Pharmaceuticals Inc TERN.O:BUZZ - Climbs on Merck's $6.7 bln takeover deal nL4N40D0Y1

** ADMA Biologics Inc ADMA.O:BUZZ - Rises after rejecting short-seller report nL4N40D0XK

** On Holding Ltd ONON.N:BUZZ - Names co-founders as new CEOs; shares down nL6N40D0QS

** Maze Therapeutics Inc MAZE.O:BUZZ - Rises as kidney disease drug shows positive results in trial nL4N40D105

** Beam Therapeutics Inc BEAM.O:BUZZ - Rises after gene-editing drug shows promise in rare lung and liver disease nL4N40D10W

** Honeywell International Inc HON.O:

** Lockheed Martin Corp LMT.N:BUZZ - Gain on new US defense production agreements nL4N40D11V

** National Bank Holdings Corp NBHC.N:BUZZ - Piper Sandler bullish on National Bank Holdings, starts coverage with 'overweight' rating nL4N40D11Y

** Chewy Inc CHWY.N:BUZZ - Gains after Q4 profit beat nL4N40D1CJ

** PDD Holdings Inc PDD.O:BUZZ - Falls as quarterly revenue misses estimates nL6N40D0R4

** Anavex Life Sciences Corp AVXL.O:BUZZ - Withdraws EU filing for Alzheimer's drug, shares fall nL4N40D12Z

** KBH Home KBH.N:BUZZ - Down as demand weighs on Q1 results, 2026 forecast nL4N40D121

** Sturm, Ruger & Company Inc RGR.N:BUZZ - Rises after report says Beretta pushes to increase stake nL4N40D135

** Forgent Power Solutions Inc FPS.N:BUZZ - Slides as PE sponsor to offload after February IPO nL6N40D0TC

** Sarepta Therapeutics Inc SRPT.O:BUZZ - Rises after muscle disease drugs show promise in early-to-mid stage trials nL4N40D148

** Kilroy Realty Corp KRC.N:

** BXP Inc BXP.N:

** $Vornado Realty Trust(VNO-N)$ VNO.N:

** SL Green Realty Corp SLG.N:BUZZ - BMO cuts PT on office REITs amid AI‑driven demand risks nL4N40D14E

** IMUNON Inc IMNN.O:BUZZ - Rises as ovarian cancer drug prolongs survival in mid-stage study nL4N40D14W

** Tempus AI Inc TEM.O:BUZZ - Rises after partnering with Daiichi Sankyo for cancer drug nL4N40D15T

** Paychex Inc PAYX.O:BUZZ - Rises after Q3 profit beat nL4N40D169

** Enliven Therapeutics Inc ELVN.O:BUZZ - Gains after Jones raises PT on increased takeover appeal nL4N40D11F

** Liberty Energy Inc LBRT.N:BUZZ - Drops after planned $450 mln convertible offering announced nL6N40D0VL

** DigitalOcean Holdings Inc DOCN.N:BUZZ - Rises after boosted $800 mln stock sale nL6N40D13O

** BWX Technologies Inc BWXT.N:BUZZ - BofA lifts BWXT's PT on strong growth potential; shares rise nL4N40D17B

** Generac Holdings Inc GNRC.N:BUZZ - Slides on plan to reorganize business segments nL4N40D1KU

** Bunge Global Ltd BG.N:BUZZ - Slips after Spruce Point says it is short on co nL4N40D19O

** HF Sinclair Corp DINO.N:

** Marathon Petroleum Corp MPC.N:

** Phillips 66 < PSX.N>:

** Valero Energy Corp VLO.N:

BUZZ - Raymond James lifts PTs on US refiners as Mideast disruptions boost margins nL4N40D19S

** GoPro Inc GPRO.O:BUZZ - To debut GP3-powered cameras in April, shares rise nL6N40D0WE

** Blaize Holdings Inc BZAI.O:BUZZ - Surges after smaller-than-expected Q4 loss nL4N40D1DF

** Cintas Corp CTAS.O:BUZZ - Up after boosting annual sales, profit forecasts nL6N40D0Y2

** Apogee Therapeutics Inc APGE.O:BUZZ - Resumes climb after $350 mln share sale nL6N40D0YL

** 10x Genomics Inc TXG.O:BUZZ - Rises on collaboration to build patient tissue database nL4N40D0UH

** Figma Inc FIG.N:BUZZ - Oppenheimer initiates Figma with 'perform;' shares fall nL6N40D116

** Sandisk Corp SNDK.O:

** Micron Technology Inc MU.O:

** Seagate Technology Holdings PLC STX.O:

** Western Digital Corp WDC.O:

BUZZ - Memory chipmakers drop after Google announces memory-saving algorithm nL6N40D114

** Corcept Therapeutics Inc CORT.O:BUZZ - Rises after FDA approves ovarian cancer drug nL4N4080OB

** Fundrise Innovation Fund VCX.N:BUZZ - Continues to surge after NYSE listing last week nL6N40D13U

** NOV Inc NOV.N:BUZZ - Rises on $200 mln Brazil subsea expansion plan nL4N40D1JP

** Flutter Entertainment PLC FLUT.N:BUZZ - Falls after UBS halves price target nL4N40D12S

** Denali Therapeutics Inc DNLI.O:BUZZ - Climbs after US FDA approves co's genetic disorder therapy nL6N40D14J

** JetBlue Airways Corp JBLU.O:BUZZ - Rises after report it is exploring a sale nL4N40D1PF

(Rajarshi Roy and Pragyan Kalita)

((Pragyan.Kalita@thomsonreuters.com))