NewAmsterdam Pharma posts BROADWAY trial presentation on obicetrapib kidney outcomes

Reuters
Yesterday
NewAmsterdam Pharma posts BROADWAY trial presentation on obicetrapib kidney outcomes
  • NewAmsterdam Pharma published a medical research presentation on CETP inhibition with obicetrapib and kidney function outcomes in patients at high cardiovascular risk, reporting results from the BROADWAY trial and a post hoc pooled analysis with the BROOKLYN trial.
  • The pooled analysis included 2,832 randomized participants with at least 1 postbaseline eGFR assessment and 1,897 participants with at least 1 postbaseline UACR measurement.
  • Annualized eGFR decline was -0.41 mL/min/1.73 m2 per year with obicetrapib versus -1.08 mL/min/1.73 m2 per year with placebo, with a reported difference of 0.67 and nominal P=0.02.
  • Composite renal events were reported in 1.9% of participants on obicetrapib versus 3.0% on placebo.
  • The presentation reported no significant difference between groups in annualized changes in UACR.


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