港股异动 | 再鼎医药(09688)涨超4% 宣布与勃林格殷格翰合作开发创新双DLL3靶向药物联合疗法

智通财经
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智通财经APP获悉,再鼎医药(09688)涨超4%,截至发稿,涨3.84%,报18.1港元,成交额8271.49万港元。

消息面上,4月15日,据再鼎医药官微消息,公司与勃林格殷格翰宣布一项临床合作,着力开发一种创新的双DLL3靶向药物联合疗法。Ib/II期研究将评估再鼎医药的靶向DLL3的ADC zocilurtatug pelitecan(zoci,原名ZL-1310)与勃林格殷格翰的DLL3/CD3 T细胞衔接器obrixtamig联合使用的安全性、耐受性及初步临床活性。

据介绍,Zocilurtatug pelitecan(简称zoci)是再鼎医药开发的一款靶向DLL3的ADC,旨在向DLL3阳性肿瘤细胞递送强效细胞毒性载荷,用于ES-SCLC治疗。最新全球I期结果显示,zoci在既往接受治疗后的ES-SCLC患者,包括在脑转移患者中,表现出强效且持久的缓解,同时具有良好的安全性。在此基础上,该项目已进入全球III期注册性研究。

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