劲方医药-B午前涨超4% 公司公布泛RAS抑制剂GFH276临床前研究数据

新浪港股
Apr 22
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  劲方医药-B(02595)盘中涨近6%,截至发稿,股价上涨4.41%,现报45.94港元,成交额2121.73万港元。

  劲方医药宣布,公司自主开发的口服Pan RAS(ON)抑制剂GFH276临床前研究数据,于当地时间4月21日登陆美国癌症研究协会(AACR)年会壁报展示。壁报显示GFH276在多种RAS突变的动物模型中,以低至1/3剂量即可达到或超越RMC-6236的抑瘤效果。

  此外,GFH276与西妥昔单抗、化疗药物或PD-1单抗分别联用的动物实验中,可展现显著的抑瘤增效及无瘤生存期延长。据悉,GFH276为全球第三款进入临床试验的Pan RAS抑制剂,并在临床早期数据中显示契合临床前疗效及安全性的初步结果。

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