港股异动 | 云顶新耀(01952)早盘涨超4% 于2026年AACR年会首次公布EVM16人体临床试验数据

智通财经
Apr 21

智通财经APP获悉,云顶新耀(01952)早盘涨超4%,截至发稿,涨4.23%,报41.34港元,成交额2610.75万港元。

消息面上,据云顶新耀官微消息,近日,公司宣布在2026年美国癌症研究协会(AACR)年会上公布其自主研发的mRNA个性化肿瘤治疗性疫苗EVM16单药治疗及联合PD-1抑制剂(替雷利珠单抗)治疗晚期实体瘤的首次人体临床试验(FIH)数据。该临床试验由北京大学肿瘤医院与复旦大学附属肿瘤医院联合发起,并于2025年3月完成首例患者给药。结果显示,EVM16在晚期实体瘤患者中展现出良好的安全性和耐受性、显著的免疫原性及积极的初步疗效信号,支持进一步临床开发推进。

EVM16是云顶新耀自主研发的mRNA个性化肿瘤治疗性疫苗,根据每位患者特有的肿瘤细胞突变,通过EVER-NEO-1“妙算”系统识别具有较高免疫原性的肿瘤新抗原,并设计编码数十种肿瘤新抗原的mRNA治疗性疫苗。EVM16通过LNP靶向递送系统在体内进行高效的抗原呈递,激活患者自身的新抗原特异性T细胞免疫,进而达到杀伤肿瘤细胞和治疗癌症的目的。

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