港股异动 | 康方生物(09926)高开逾9% 依沃西联合化疗战胜PD-1联合化疗OS结果发布

智通财经
Jun 01

智通财经APP获悉,康方生物(09926)今日大幅高开,截至发稿,涨9.23%,报129港元,成交额3.62亿港元。

消息面上,康方生物PD-1/VEGF双抗依沃西单抗联合化疗一线治疗晚期鳞状非小细胞肺癌的III期HARMONi-6研究于ASCO大会全体会议(Plenary Session)公布最新结果。与替雷利珠单抗联合化疗相比,依沃西组患者死亡风险下降34%,OS达到统计学显著性,两年生存率64.7% vs 48.6%。

HARMONi-6共入组532例患者,中央型鳞癌占比约63%,PD-L1 TPS<1%患者占39%,多部位转移、肝转移及脑转移患者占比约33.8%。核心数据显示:依沃西组mOS达到27.89个月,对照组为23.69个月,延长近4个月;HR为0.66,p值0.0017,明显优于预设统计学边界0.0049。

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