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　　高盛发布研报称，上调科伦博泰生物（06990）2027及2028年每股盈利预测至7.51元及14.46元人民币，目标价由561.4港元上调至582.95港元，维持“买入”评级，认为科伦博泰有望成为具影响力的全球ADC药企。

　　科伦博泰公布靶向人滋养细胞表面抗原2（TROP2）的抗体偶联药物（ADC）芦康沙妥珠单抗（sac-TMT，亦称SKB264/MK-2870），联合默沙东的抗PD-1单抗“可瑞达”，一线治疗PD-L1阴性的局部晚期或转移性NSCLC的三期临床研究（OptiTROP-Lung06）已达到主要终点。该行预期，临床研究的正面结果为sac-TMT在治疗1L NSCLC研究的关键一步，将Lung06的成功率由81%上调至90%，海外1L NSCLC PD-L1 肿瘤比例分数（TPS）<50%适应症成功率由54%上调至63%。

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