【瑞典新研究:RNA预处理可助提升胰岛移植效率】瑞典卡罗琳医学院的研究人员最新开发出一种靶向核糖核酸技术,可在胰岛移植前对胰岛细胞进行短暂预处理,使其移植后能更快地重建血液供应,并有望减少移植所需的供体胰岛数量。对糖尿病小鼠进行的实验证实,与移植未经处理胰岛的小鼠相比,移植预处理胰岛的小鼠体内,存活并能保持功能的胰岛β细胞数量更多,血糖控制情况也更好。研究人员认为,如果进一步研究证实安全有效,这种RNA预处理技术有望提高有限供体胰岛的利用效率,使更多患者受益。此外,该技术也有可能用于改善其他类型的细胞移植效果。相关研究成果已发表在国际学术期刊《信号转导与靶向治疗》上。
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