普拉德-威利综合征患者团体称有死亡病例与Neurocrine公司治疗遗传性疾病的药物有关,该公司股价下跌

路透中文
Aug 12
BUZZ-普拉德-威利综合征患者团体称有死亡病例与Neurocrine公司治疗遗传性疾病的药物有关,该公司股价下跌

8月12日 - ** 制药公司Neurocrine Biosciences(NBIX.O)的股价在盘前交易中下跌4.9%,至154美元

** 周二,三家机构发布联合声明((link)),援引上市后报告称,在接受NBIX公司药物Vykat XR治疗的患者中,已发生7例死亡病例及超过100例严重不良事件报告,该药物于2025年3月获批

** 该药物用于治疗贪食症,这是普拉德-威利综合征(Prader-Willi syndrome)的标志性症状。该遗传性疾病由第15号染色体的全部或部分缺失引起,这些缺失会影响基因表达的调控,即基因的开启与关闭机制

** 不过,相关机构强调,这些报告并未确立Vykat XR与不良结果之间的因果关系

**今年早些时候,Neurocrine通过以29亿美元收购Soleno Therapeutics((link)),将Vykat XR纳入其产品组合

** 美国食品药品监督管理局(FDA)数据库显示,有4例死亡病例与该药物相关

** Neurocrine公司和美国FDA尚未立即回应路透的置评请求

** 截至上一交易日收盘,该股年内累计上涨14.2%

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