莫德纳联合默沙东研发的个性化mRNA癌症疫苗intismeran autogene,全球首个大型III期临床读出阳性结果。此次intismeran的开发是AI for Science(AI4S)落地新药研发典型案例。流程上从患者肿瘤DNA测序,再靠AI筛选新抗原、设计mRNA序列,最终做到一人一药的定制化疫苗,意味着AI不再只做研发环节辅助,已经贯穿从样本分析到候选药物产出的完整链条。
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