智通财经APP获悉，和誉-B(02256)高开逾6%，截至发稿，涨6.53%，报9.875港元，成交额22.71万港元。
消息面上，8月31日，和誉-B发布公告，公司的附属公司上海和誉生物医药科技有限公司(“和誉医药”)宣布其口服、高效力且广泛覆盖多种KRAS改变的小分子pan-KRAS抑制剂ABSK211用于治疗携带KRAS基因改变的晚期实体瘤患者的I期临床试验已完成首例患者给药。
此前，公司在研的口服、高效力、高选择性小分子pan-KRAS抑制剂ABSK211用于治疗携带KRAS基因改变的晚期实体瘤患者的新药临床试验(IND)申请已获美国食品药品监督管理局(FDA)批准。临床前研究结果显示，ABSK211在单药及联合治疗场景中均展现出积极的抗肿瘤活性及良好的选择性，有望为携带KRAS基因改变的实体瘤患者提供新的治疗选择。
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