Takeda Reports New Psoriasis Treatment Outperformed Competitor in Phase 3 Trial

MT Newswires Live
Sep 30

Takeda (TAK) said Wednesday that its experimental pill zasocitinib showed superior results compared with the rival treatment deucravacitinib across the primary and key secondary endpoints in a Phase 3 trial for adults with plaque psoriasis.

Over 36.5% of patients given the new medication achieved complete skin clearance at 16 weeks, compared with 13.9% of those taking the competitor drug, the company said.

Takeda said 62.5% of subjects on zasocitinib saw a 90% reduction in disease severity by the 16-week mark, while the competing drug yielded a 34% success rate.

The company said up to 93% of patients who achieved a response at week 24 maintained their skin-clearance results through week 52 in one Phase 3 study. Takeda also reported improvements in itching and quality of life as early as week 2 when compared with a placebo and the chronic inflammatory drug apremilast.

Takeda said zasocitinib is under review by the US Food and Drug Administration and the European Medicines Agency for moderate-to-severe plaque psoriasis.

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