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Ionis Pharmaceuticals

72.15

-2.0900-2.82%

Post-market: 72.150.00000.00%17:50 EDT

Volume:1.95M

Turnover:141.16M

Market Cap:11.92B

PE:-30.32

High:74.05

Open:74.00

Low:71.87

Close:74.24

52wk High:86.74

52wk Low:23.95

Shares:165.19M

Float Shares:164.00M

Volume Ratio:0.70

T/O Rate:1.19%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.3800

EPS(LYR):-2.3812

ROE:-70.80%

ROA:-7.31%

PB:24.37

PE(LYR):-30.30

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Overview Company News Filings

BUZZ-Ionis drops after forecasting 2026 revenue below expectations

Ionis Pharmaceuticals reports Q4 EPS ($1.41), consensus ($1.22)

Ionis Pharmaceuticals Shares Down 5.8% Premarket After Co Forecast FY26 Revenue Below Estimates

THOMSON REUTERS

Ionis Pharma Q4 revenue beats expectations, helped by TRYNGOLZA EU launch

GUIDANCE: (IONS) Ionis Pharmaceuticals Expects Full Year 2026 Revenue Range $800M-$825M, vs. FactSet Est of $915M

MT Newswires Live

Stock Track | Ionis Pharmaceuticals Plunges 5.20% in Pre-Market on Widening Q4 Loss

Earnings Flash (IONS) Ionis Pharmaceuticals Posts Q4 Revenue $203M, vs. FactSet Est of $157.7M

MT Newswires Live

Ionis Q4 revenue USD 203 million, up 64% on commercial revenue

Ionis Pharmaceuticals Q4 Adj. EPS $(1.15) Beats $(1.32) Estimate, Sales $203.000M Beat $156.094M Estimate

BRIEF-Ionis Pharmaceuticals Q4 Revenue USD 203 Million Vs. IBES Estimate USD 156.1 Million

Ionis Pharmaceuticals Q4 Adjusted Operating Expenses USD 375 Million

THOMSON REUTERS

Ionis Pharmaceuticals Inc: Outlook 2026 Revenue $800- $825 Mln

THOMSON REUTERS

Ionis Pharmaceuticals Q4 Operating Income USD -215 Million

THOMSON REUTERS

Ionis Pharmaceuticals Q4 Operating Expenses USD 418 Million

THOMSON REUTERS

U.S. Earnings Preview: Before Market Open Feb. 25

Ionis Pharmaceuticals to Present at Upcoming Investor Conferences

A Look At Ionis Pharmaceuticals (IONS) Valuation After Recent Share Price Strength And Mixed Analyst Signals

Simply Wall St.

Earning Preview: Ionis Pharmaceuticals this quarter’s revenue is expected to increase by 13.44%, and institutional views are bullish

Ionis Pharmaceuticals Inc. updates time for financial results webcast

Ionis Updates Time for Fourth Quarter and Full Year 2025 Financial Results Webcast

THOMSON REUTERS

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This is a 167.44 percent decrease over losses of $(0.43) per share","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/02/50844371/ionis-pharmaceuticals-q4-adj-eps-1-15-beats-1-32-estimate-sales-203-000m-beat-156-094m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2614089271","title":"BRIEF-Ionis Pharmaceuticals Q4 Revenue USD 203 Million Vs. IBES Estimate USD 156.1 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2614089271","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614089271?lang=en_us&edition=fundamental","pubTime":"2026-02-25 20:00","pubTimestamp":1772020847,"startTime":"0","endTime":"0","summary":"Feb 25  - Ionis Pharmaceuticals Q4 adjusted operating income USD -172 million vs. IBES estimate USD -210.3 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was automatically generated by Dow Jones using technology from Automated Insights.The following companies are among those expected to report their latest financial results before the market opens.TJX Cos.'s fourth-quarter EPS is forecast at $1.38, compared with $1.23 in the prior-year period. Adjusted EPS is forecast at $1.39.Lowe's Cos.'s fourth-quarter EPS is forecast at $1.92, compared with $1.99 in the prior-year period. Adjusted EPS is forecast at $1.94.United Therapeutics Corp.'s fourth-quarter EPS is forecast at $6.67, compared with $6.19 in the prior-year period. Adjusted EPS is forecast at $6.87.APi Group Corp.'s fourth-quarter EPS is forecast at 26 cents. Adjusted EPS is forecast at 42 cents.Ionis Pharmaceuticals Inc.'s fourth-quarter EPS is forecast at a loss of $1.32, compared with a loss of 66 cents in the prior-year period. Adjusted EPS is forecast at a loss of $1.31.Owens Corning's fourth-quarter EPS is forecast at $1.35, compared with a loss of $2.91 in the","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B19Z9Z06.USD","BK4597","LU2048586759.USD","BK4504","LU2133065610.SGD","LU2506952170.USD","IONS","LU1674673691.USD","IE00B894F039.SGD","PNW","LU1989772840.SGD","LU2506952097.USD","IE00B5TLWC47.USD","LU1074936037.SGD","LU1917777945.USD","OC","BK4581","LU0950375773.USD","LU2237443978.SGD","LU1674673428.USD","UTHR","BK4139","BK4094","LU2092937221.SGD","BK4592","LU1506573853.SGD","LU2041044095.USD","LU2023250504.SGD","LU0198837287.USD","IE00B2PGVK34.USD","BK4534","BK4086","LU2237443622.USD","BK4519","LU0314106906.USD","LU0823417737.USD","BK4083","LU0312595415.SGD","LU0094547139.USD","IE00BGHQF417.EUR","LU0868494708.USD","LU0942090050.USD","TJX","LU1571399168.USD","LOW","LU2275660780.HKD","LU2237443549.SGD","BK4081","LU0868494617.USD","LU1974910355.USD"],"gpt_icon":0},{"id":"2612837402","title":"Ionis Pharmaceuticals to Present at Upcoming Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2612837402","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612837402?lang=en_us&edition=fundamental","pubTime":"2026-02-19 20:05","pubTimestamp":1771502728,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on February 19, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260219:nNDL2T9Cfp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2612428735","title":"A Look At Ionis Pharmaceuticals (IONS) Valuation After Recent Share Price Strength And Mixed Analyst Signals","url":"https://stock-news.laohu8.com/highlight/detail?id=2612428735","media":"Simply Wall 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