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Ionis Pharmaceuticals

79.48

-2.1800-2.67%

Post-market: 79.480.00000.00%18:55 EST

Volume:1.89M

Turnover:150.01M

Market Cap:12.87B

PE:-49.27

High:82.57

Open:82.24

Low:78.61

Close:81.66

52wk High:86.15

52wk Low:23.95

Shares:161.97M

Float Shares:161.00M

Volume Ratio:0.73

T/O Rate:1.17%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.6132

EPS(LYR):-3.0358

ROE:-40.04%

ROA:-5.68%

PB:20.83

PE(LYR):-26.18

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Overview Company News Filings

Ionis Pharmaceuticals (IONS) Gets a Hold from Bernstein

BRIEF-Biogen Says Co Received European Commission Approval For High Dose Regimen Of SPINRAZA

Biogen Receives European Commission Approval for High Dose Regimen of Spinraza® (Nusinersen) for Spinal Muscular Atrophy

THOMSON REUTERS

Biogen - High Dose Spinraza Approved in Japan, Decision Expected by April 3, 2026

THOMSON REUTERS

Ionis Pharmaceuticals raises TRYNGOLZA peak sales guidance to over $2 billion for sHTG

Ionis Pharmaceuticals Announces 2025 Achievements and Outlines 2026 Milestones

Ionis Pharmaceuticals EVP Shannon L. Devers Reports Sale of Common Shares

BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe's

BUZZ-Ionis hits seven-year high after partner GSK reveals promising hepatitis B trial results

GSK's chronic hepatitis B therapy shows promise in key studies, analysts await full data

Ionis and GSK Report Positive Phase 3 Results for Bepirovirsen in Chronic Hepatitis B

Ionis Partner GSK Announces Positive Topline Results From B-Well 1 and B-Well 2 Phase 3 Studies for Bepirovirsen, a Potential First-in-Class Medicine for Chronic Hepatitis B

THOMSON REUTERS

Ionis Pharmaceuticals EVP Research Eric Swayze Reports Sale of Common Shares

Ionis Pharmaceuticals Files Initial Beneficial Ownership Statement for Holly B. Kordasiewicz, EVP and Chief Development Officer

Ionis Pharmaceuticals CEO to Present Company Overview at J.P. Morgan Healthcare Conference

Assessing Ionis Pharmaceuticals (IONS) Valuation After Analyst Optimism And FDA Approval Of Tryngolza

Simply Wall St.

Ionis Pharmaceuticals Is Maintained at Overweight by Wells Fargo

The Year-End 2025 Biotech Rally And What It Means For 2026

Benzinga_recent_news

Will FDA Approval of Tryngolza and Analyst Support Change Ionis Pharmaceuticals' (IONS) Narrative?

Simply Wall St.

Cathie Wood Dumps $11 Milllion Worth of Tesla Stock While Doubling Down on These Notable Crypto Plays

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Japan, Decision Expected by April 3, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2603544944","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2603544944?lang=en_us&edition=fundamental","pubTime":"2026-01-13 00:05","pubTimestamp":1768233900,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nTUAMZRB5:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4588","LU0109394709.USD","BK4139","IE00B894F039.SGD","IE00B19Z9P08.USD","IE00B19Z9Z06.USD","BIIB","BK4533","BK4532","LU0889565916.HKD","LU0234570918.USD","LU0320765992.SGD","BK4585"],"gpt_icon":0},{"id":"2602128514","title":"Ionis Pharmaceuticals raises TRYNGOLZA peak sales guidance to over $2 billion for sHTG","url":"https://stock-news.laohu8.com/highlight/detail?id=2602128514","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602128514?lang=en_us&edition=fundamental","pubTime":"2026-01-12 20:03","pubTimestamp":1768219414,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief on January 12, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nNDL2p9r92:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2602514918","title":"Ionis Pharmaceuticals Announces 2025 Achievements and Outlines 2026 Milestones","url":"https://stock-news.laohu8.com/highlight/detail?id=2602514918","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602514918?lang=en_us&edition=fundamental","pubTime":"2026-01-12 20:01","pubTimestamp":1768219303,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on January 12, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nNDL8wdyZV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2602304969","title":"Ionis Pharmaceuticals EVP Shannon L. Devers Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2602304969","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602304969?lang=en_us&edition=fundamental","pubTime":"2026-01-10 06:09","pubTimestamp":1767996541,"startTime":"0","endTime":"0","summary":"Shannon L. Devers, EVP and Chief Human Resources Officer of Ionis Pharmaceuticals Inc., has reported a disposal of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on January 09, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260109:nNDL9k5Txf:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis Pharmaceuticals EVP Shannon L. Devers Reports Sale of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2601383269","title":"BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe's","url":"https://stock-news.laohu8.com/highlight/detail?id=2601383269","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601383269?lang=en_us&edition=fundamental","pubTime":"2026-01-08 02:51","pubTimestamp":1767811889,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe'sEikon search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call newsletter: https://ref","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL6N3Y80LY:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ARWR","W","HUM","CDE","NVDA","RTX","HSY","BKR","TXR","MTB","VTYX","DECK","VERA","EXE","PRAX","MTYY","CL","HAL","RZLT","CALM","LBRT","HL","PENG","UNF","LOW","AJG","ACI","GE","COMP","CRNX","GLUE","LNG","FSLR","NEM","AIR","IONS","BA","UNP","APOG","SLB","LMT"],"gpt_icon":1},{"id":"2601073508","title":"BUZZ-Ionis hits seven-year high after partner GSK reveals promising hepatitis B trial results","url":"https://stock-news.laohu8.com/highlight/detail?id=2601073508","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601073508?lang=en_us&edition=fundamental","pubTime":"2026-01-08 00:21","pubTimestamp":1767802900,"startTime":"0","endTime":"0","summary":"BUZZ-Ionis hits seven-year high after partner GSK reveals promising hepatitis B trial results** Drugmaker Ionis Pharmaceuticals' IONS.O shares rise 4.8% to $85.41, hitting a nearly seven-year high** C","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL6N3Y80Y6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1670756490.USD","LU0203345920.USD","LU0321505868.SGD","LU1302929846.USD","LU0203347892.USD","LU0575583348.USD","LU1400636491.USD","GSK.UK","LU0225771236.USD","LU0321505439.SGD","IE0034235071.USD","BK4139","LU0161305163.EUR","LU0289739699.SGD","BK5011","IE00BQJZX424.USD","LU1064927863.SGD","LU0545562505.USD","LU0971552830.HKD","LU1098665638.USD","LU1015430645.USD","LU0058720904.USD","IE00BWDBJ516.SGD","LU1645745479.HKD","LU1487256676.USD","LU1046248800.SGD","LU0109981661.USD","IE00B3T34201.USD","LU1309081286.SGD","LU0985481810.HKD","LU1481600234.SGD","LU0211331839.USD","LU0971552673.USD","LU0225284248.USD","LU1035777561.USD","LU0306807586.USD","LU0306806265.USD","LU1228905037.USD","LU1202635105.USD","LU1481599808.USD","LU1400636574.HKD","IONS","LU1228905540.USD","LU1400636657.SGD"],"gpt_icon":0},{"id":"2601273098","title":"GSK's chronic hepatitis B therapy shows promise in key studies, analysts await full data","url":"https://stock-news.laohu8.com/highlight/detail?id=2601273098","media":"Reuters","labels":["executive","productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601273098?lang=en_us&edition=fundamental","pubTime":"2026-01-07 15:24","pubTimestamp":1767770659,"startTime":"0","endTime":"0","summary":"UPDATE 3-GSK's chronic hepatitis B therapy shows promise in key studies, analysts await full dataFull data needed to assess potential for broad adoption, analysts say Drug could generate over 2 billio","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL6N3Y80EB:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive,productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1400636574.HKD","LU1046248800.SGD","LU1487256676.USD","LU0058720904.USD","IE00BWDBJ516.SGD","BK5011","LU0321505439.SGD","LU1202635105.USD","LU1400636491.USD","IE00BQJZX424.USD","LU0161305163.EUR","GSK.UK","LU1481599808.USD","LU1064927863.SGD","LU0109981661.USD","LU1645745479.HKD","LU0306806265.USD","LU1228905037.USD","LU1228905540.USD","LU1035777561.USD","LU0575583348.USD","LU1400636657.SGD","LU0545562505.USD","LU0321505868.SGD","BK4139","LU0203347892.USD","LU0211331839.USD","LU0306807586.USD","LU0289739699.SGD","LU0985481810.HKD","LU1098665638.USD","IONS","LU0971552830.HKD","LU1302929846.USD","IE0034235071.USD","LU1670756490.USD","LU0971552673.USD","LU0225771236.USD","LU1309081286.SGD","LU1481600234.SGD","IE00B3T34201.USD","LU0225284248.USD","LU0203345920.USD","LU1015430645.USD"],"gpt_icon":0},{"id":"2601822705","title":"Ionis and GSK Report Positive Phase 3 Results for Bepirovirsen in Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2601822705","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601822705?lang=en_us&edition=fundamental","pubTime":"2026-01-07 15:15","pubTimestamp":1767770118,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals Inc. announced that its partner, GSK, has reported positive topline results from the B-Well 1 and B-Well 2 Phase 3 clinical studies evaluating bepirovirsen, an investigational antisense oligonucleotide for the treatment of chronic hepatitis B . The primary endpoint was met in both trials, with bepirovirsen demonstrating a statistically significant and clinically meaningful functional cure rate. The studies included over 1,800 patients from 29 countries. Global regulatory filings for bepirovirsen are planned to begin in the first quarter of 2026. The results from these studies have already been announced.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used t","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nNDL83Y7gn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2601822779","title":"Ionis Partner GSK Announces Positive Topline Results From B-Well 1 and B-Well 2 Phase 3 Studies for Bepirovirsen, a Potential First-in-Class Medicine for Chronic Hepatitis B","url":"https://stock-news.laohu8.com/highlight/detail?id=2601822779","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601822779?lang=en_us&edition=fundamental","pubTime":"2026-01-07 15:15","pubTimestamp":1767770100,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nTUA7405MR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2601599846","title":"Ionis Pharmaceuticals EVP Research Eric Swayze Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2601599846","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601599846?lang=en_us&edition=fundamental","pubTime":"2026-01-07 06:35","pubTimestamp":1767738952,"startTime":"0","endTime":"0","summary":"Eric Swayze, Executive Vice President of Research at Ionis Pharmaceuticals Inc., reported a disposal of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on January 06, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nNDLqGTWk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2601846593","title":"Ionis Pharmaceuticals Files Initial Beneficial Ownership Statement for Holly B. Kordasiewicz, EVP and Chief Development Officer","url":"https://stock-news.laohu8.com/highlight/detail?id=2601846593","media":"Reuters","labels":["executive","shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601846593?lang=en_us&edition=fundamental","pubTime":"2026-01-07 06:35","pubTimestamp":1767738928,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals Files Initial Beneficial Ownership Statement for Holly B. Kordasiewicz, EVP and Chief Development Officer. Ionis Pharmaceuticals Inc. has filed an initial statement of beneficial ownership with the U.S. Securities and Exchange Commission. The filing lists Holly B. Kordasiewicz, Executive Vice President and Chief Development Officer, as the beneficial owner. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on January 06, 2026, and is solely res","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nNDLvDThP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis Pharmaceuticals Files Initial Beneficial Ownership Statement for Holly B. Kordasiewicz, EVP and Chief Development Officer","news_tag":"executive,shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2601894618","title":"Ionis Pharmaceuticals CEO to Present Company Overview at J.P. Morgan Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2601894618","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601894618?lang=en_us&edition=fundamental","pubTime":"2026-01-06 20:05","pubTimestamp":1767701111,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals Inc. will present a company overview at the 44th Annual J.P. Morgan Healthcare Conference on Tuesday, January 13, 2026. The presentation by CEO Brett P. Monia, Ph.D., will be available via live webcast on the Ionis website, with a replay accessible within 48 hours.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on January 06, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260106:nNDLbqJkhV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2601860053","title":"Assessing Ionis Pharmaceuticals (IONS) Valuation After Analyst Optimism And FDA Approval Of Tryngolza","url":"https://stock-news.laohu8.com/highlight/detail?id=2601860053","media":"Simply Wall St.","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601860053?lang=en_us&edition=fundamental","pubTime":"2026-01-06 14:14","pubTimestamp":1767680057,"startTime":"0","endTime":"0","summary":"Recent optimism from several Wall Street firms toward Ionis Pharmaceuticals (IONS) has been tied to its broad RNA-focused pipeline and the recent FDA approval of Tryngolza, a treatment for familial chylomicronemia syndrome and acute pancreatitis.\nSee our latest analysis for Ionis Pharmaceuticals.\nDespite a mixed recent patch, with the latest 1-day and 30-day share price returns both in negative territory, Ionis shares have a 90-day share price return of 12.25% and a very large 1-year total...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-after-analyst","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/assessing-ionis-pharmaceuticals-ions-valuation-after-analyst","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2601636831","title":"Ionis Pharmaceuticals Is Maintained at Overweight by Wells Fargo","url":"https://stock-news.laohu8.com/highlight/detail?id=2601636831","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601636831?lang=en_us&edition=fundamental","pubTime":"2026-01-06 02:55","pubTimestamp":1767639300,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  January 05, 2026 13:55 ET (18:55 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2600708537","title":"The Year-End 2025 Biotech Rally And What It Means For 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2600708537","media":"Benzinga_recent_news","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2600708537?lang=en_us&edition=fundamental","pubTime":"2025-12-31 23:54","pubTimestamp":1767196440,"startTime":"0","endTime":"0","summary":"Biotechnology stocks are wrapping up 2025 on a high note, bouncing back from a rocky start to deliver some of the year’s most impressive gains. What began as a sector weighed down by tariff fears and political noise has transformed into one of the market’s standout performers, powered by deal making, drug approvals, and breakthrough clinical results. The big question heading into 2026 is simple: can this momentum last?The performance metrics speak volumes. The iShares Biotechnology ETF  has climbed 29.51% year to date through December 29, while the State Street SPDR S&P Biotech ETF  has done even better with gains around 35.84%. The Nasdaq Biotechnology Index sits at 5,766.59, marking a 34% jump for the year.Regulatory wins provided another boost. The FDA greenlit 44 new therapies in 2025, with 26 approvals coming in the second half alone. December saw notable wins including Cytokinetics Incorporated’s  Myqorzo for a heart condition, marking the company’s first approval after 27 years ","market":"us","thumbnail":"/next-assets/images/benzinga-post-card-placeholder.svg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["/next-assets/images/benzinga-post-card-placeholder.svg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/news/25/12/49650052/the-year-end-2025-biotech-rally-and-what-it-means-for-2026","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/25/12/49650052/the-year-end-2025-biotech-rally-and-what-it-means-for-2026","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["NVIW.SI","ITCI","LU1935042991.SGD","IE00BVYPNW00.USD","OMER","SG9999014880.SGD","LU0306807586.USD","LU0471298694.HKD","BK4505","SQQQ","IE00B1BXHZ80.USD","PFE","MNQmain","QLD","EYPT","QID","RNA","MNPR","IONS","LU2430703178.SGD","USJW.SI","CYTK","TQQQ","TSYW.SI","LU2089984988.USD","LU2063271972.USD","VRNA","JNJ","LU0256863811.USD","BK4581",".IXIC","NVS","GPCR","BK4532","LU2592432038.USD","LU0823434740.USD","PSQ","USAW.SI","LU1116320737.USD","LU0432979614.USD","NQmain","IE00BBT3K403.USD","SG9999014906.USD","LU1037948897.HKD","MRK","IBB","IE00BJT1NW94.SGD","IE0005OL40V9.USD"],"gpt_icon":1},{"id":"2593102073","title":"Will FDA Approval of Tryngolza and Analyst Support Change Ionis Pharmaceuticals' (IONS) Narrative?","url":"https://stock-news.laohu8.com/highlight/detail?id=2593102073","media":"Simply Wall St.","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2593102073?lang=en_us&edition=fundamental","pubTime":"2025-12-22 13:17","pubTimestamp":1766380653,"startTime":"0","endTime":"0","summary":"In recent months, Ionis Pharmaceuticals secured FDA approval for Tryngolza, its first independently launched RNA-targeted therapy for familial chylomicronemia syndrome, while multiple research firms reiterated positive views on the company’s prospects. This combination of regulatory success and renewed analyst confidence highlights Ionis’s evolution from a primarily R&D-focused biotech toward a more fully fledged commercial organization.\nNow, we’ll explore how Ionis’s first independent...","market":"us","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/will-fda-approval-of-tryngolza-and-analyst-support-change-io","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-ions/ionis-pharmaceuticals/news/will-fda-approval-of-tryngolza-and-analyst-support-change-io","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2592404139","title":"Cathie Wood Dumps $11 Milllion Worth of Tesla Stock While Doubling Down on These Notable Crypto Plays","url":"https://stock-news.laohu8.com/highlight/detail?id=2592404139","media":"Benzinga","labels":["shareholding","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592404139?lang=en_us&edition=fundamental","pubTime":"2025-12-19 15:00","pubTimestamp":1766127600,"startTime":"0","endTime":"0","summary":"On Thursday, Cathie Wood-led Ark Invest made significant trades involving Tesla, Coinbase, and Brera Holdings.","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"043923b8d36f8cfd5c3ba60252c2c8ad","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/etfs/broad-u-s-equity-etfs/25/12/49497703/cathie-wood-dumps-11-milllion-worth-of-tesla-stock-while-doubling-down-on-these-notable-crypto-plays","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999015978.USD","LU2087621335.USD","LU2462157665.USD","LU0466842654.USD","LU2360107168.USD","IE00B1BXHZ80.USD","IE00B1XK9C88.USD","LU1852331112.SGD","LU0672654240.SGD","BK4555","LU0077335932.USD","LU1674673691.USD","LU1366192091.USD","IE00BK4W5M84.HKD","LU0345770993.USD","LU1778281490.HKD","LU0719512351.SGD","LU1861215975.USD","IE0034235303.USD","BK4585","BK4600","LU1629891620.HKD","BK4592","LU0316494557.USD","LU1674673428.USD","BK4112","IE00BWXC8680.SGD","BK4108","LU0823414478.USD","LU0345769128.USD","LU1267930730.SGD","LU1066051498.USD","BK4511","LU2602419157.SGD","BK4539","SG9999015952.SGD","LU2326559502.SGD","ADPT","IE00B19Z8X17.USD","IE00BK4W5L77.USD","LU0820561909.HKD","LU1861220207.SGD","BK4596","LU0198837287.USD","LU2471134879.HKD","LU0708995401.HKD","LU2471134796.USD","LU0323591593.USD","BK4595","LU1861220033.SGD","RXRX","BK4574","COIN","LU2756315664.SGD","BK4548","LU2750360641.GBP","LU1551013425.SGD","BK4544","LU2250418816.HKD","LU1861559042.SGD","BK4612","BK4535","BK4588","IE00B19Z9505.USD","IE00B19Z8W00.USD","LU2023250330.USD","LU2063271972.USD","LU2403377893.USD","LU1435385759.SGD","LU2756315318.SGD","LU0082616367.USD","SG9999015986.USD","LU1861217088.USD","LU2360106780.USD","LU1720051017.SGD","BK4516","BK4551","LU0345770308.USD","IE00BSNM7G36.USD","BK4604","LU0689472784.USD","LU0320765059.SGD","BK4099","BK4598","LU2290526834.HKD","LU1429558221.USD","LU2456880835.USD","LU0097036916.USD","LU0234572021.USD","BK4581","IE00BJLML261.HKD","SG9999015945.SGD","LU0210536198.USD","LU0943347566.SGD","LU1232071149.USD","LU0820562030.AUD","LU2896262040.SGD","IONS","LU1720051108.HKD","LU2108987350.USD","LU2213496289.HKD","LU2471134952.CNY","LU1839511570.USD","BK4527","BK4534","LU2420271590.USD","LU0348723411.USD","LU0053666078.USD","BK4554","LU1914381329.SGD","LU0109391861.USD","BK4533","LU1145028129.USD","BK4550","LU1861558580.USD","LU2417539215.USD","LU0823411888.USD","LU2236285917.USD","LU1551013342.USD","LU0820561818.USD","SLMT","LU2360107671.USD","LU1066053197.SGD","LU2249611893.SGD","LU1066051811.HKD","LU2471134523.USD","LU2750360997.AUD","LU1066051225.USD","LU0964807845.USD","LU1548497426.USD","LU0234570918.USD","LU2357305700.SGD","BK4543","TSLA","LU0056508442.USD","LU0345769631.USD"],"gpt_icon":1}],"pageSize":20,"totalPage":10,"pageCount":1,"totalSize":197,"code":"91000000","status":"200"}]}}