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Ionis Pharmaceuticals

33.10

+1.394.38%

Volume:851.69K

Turnover:27.91M

Market Cap:5.27B

PE:-11.04

High:33.15

Open:32.25

Low:32.01

Close:31.71

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Overview Company News Filings

Wainzua (Eplontersen) Approved in the EU for the Treatment of Hereditary Transthyretin-Mediated Amyloidosis in Adults With Stage 1 or Stage 2 Polyneuropathy

THOMSON REUTERS

WAINZUA (eplontersen) approved in the EU for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy

Theratechnologies Inc (THTX) Q4 2024 Earnings Call Highlights: Strong EBITDA Turnaround and ...

Ionis to present at upcoming investor conferences

The Zacks Analyst Blog Highlights Merck, Sanofi, Regeneron and Ionis

Optimistic Future Outlook for Ionis Pharmaceuticals Driven by Robust Growth and Strategic Initiatives

Ionis Pharmaceuticals price target lowered to $60 from $61 at Raymond James

Pharma Stock Roundup: EU Nod to MRK's Welireg, IONS' Q4 Results & More

Ionis Pharmaceuticals Inc : Bernstein Cuts Target Price to $43 From $51

THOMSON REUTERS

BRIEF-New Positive Donidalorsen Data To Be Presented At Aaaai/Wao Joint Congress

New Positive Donidalorsen Data to Be Presented at Aaaai/Wao Joint Congress Highlight Sustained Hae Attack Rate Reduction and Disease Control

THOMSON REUTERS

Ionis Pharmaceuticals Full Year 2024 Earnings: Beats Expectations

Simply Wall St.

Ionis Pharmaceuticals Price Target Maintained With a $60.00/Share by Needham

Barclays Remains a Hold on Ionis Pharmaceuticals (IONS)

Q4 2024 Ionis Pharmaceuticals Inc Earnings Call

Thomson Reuters StreetEvents

Ionis Pharmaceuticals Inc (IONS) Q4 2024 Earnings Call Highlights: Surpassing Revenue ...

Optimistic Buy Rating for Ionis Pharmaceuticals Driven by Promising Financial Outlook and Strategic Advancements

Ionis Pharmaceuticals price target lowered to $38 from $45 at Stifel

Ionis Pharmaceuticals Q4 Revenue Growth Exceeds Guidance, Forecasts Over $600 Million In 2025 Sales

Ionis Pharmaceuticals trading resumes

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WAINZUA is the only approved medicine in the EU for the treatment of ATTRv-PN that can be self-administered monthly via an auto-injector.ATTR is caused by the accumulation of liver-derived misfolded TTR protein i","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/wainzua-eplontersen-approved-eu-treatment-110000305.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4201","CM","BK4207","BK4156","PN","CHMP","IONS","BK4139","EC","BK4087"],"gpt_icon":0},{"id":"2514823869","title":"Theratechnologies Inc (THTX) Q4 2024 Earnings Call Highlights: Strong EBITDA Turnaround and ...","url":"https://stock-news.laohu8.com/highlight/detail?id=2514823869","media":"GuruFocus.com","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514823869?lang=en_us&edition=fundamental","pubTime":"2025-02-27 15:09","pubTimestamp":1740640144,"startTime":"0","endTime":"0","summary":"Adjusted EBITDA: $20 million for fiscal year 2024, compared to minus $3 million a year ago.Net Sales: $25 million for Q4 2024, a 6.6% growth versus the same quarter last year.EGRIFTA SV Sales: $17.7 million in Q4 2024, a 4% increase year over year; full year sales were $60 million, representing 12% growth.Trogarzo Sales: $7.3 million in Q4 2024, a 12.8% increase from the same quarter last year; full year sales were $25.7 million, down 8% year over year.Cost of Sales: $6.1 million in Q4 2024, up from $5 million in the same quarter of fiscal 2023.Gross Margin: EGRIFTA SV gross margins at 91% excluding a provision, Trogarzo margins at 48%.R&D Expenses: $2.4 million in Q4 2024, down from $5.2 million last year, excluding impairment loss.Selling Expenses: $7 million in Q4 2024, compared to $6.7 million for the same period last year.G&A Expenses: $5.1 million in Q4 2024, a 38% increase from $3.7 million in Q4 2023.GuruFocus has detected 7 Warning Signs with THTX.Theratechnologies Inc  report","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/theratechnologies-inc-thtx-q4-2024-070904805.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["THTX","IONS"],"gpt_icon":0},{"id":"2514932320","title":"Ionis to present at upcoming investor conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2514932320","media":"Business Wire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514932320?lang=en_us&edition=fundamental","pubTime":"2025-02-25 20:05","pubTimestamp":1740485100,"startTime":"0","endTime":"0","summary":"CARLSBAD, Calif., February 25, 2025----Ionis Pharmaceuticals, Inc.  today announced that management will participate in fireside chats at the following investor conferences:. Raymond James 46th Annual Institutional Investors Conference on Tuesday, March 4, 2025. Leerink Partners Global Healthcare Conference 2025 on Tuesday, March 11, 2025. Barclays 27th Annual Global Healthcare Conference on Wednesday, March 12, 2025. UBS Virtual CNS Day 2025 on Monday, March 17, 2025. Stifel 2025 Virtual CNS Forum on Wednesday, March 19, 2025. For three decades, Ionis has invented medicines that bring better futures to people with serious diseases. Ionis currently has six marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient need. As the pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies in addition to advancing new approaches in gene editing. A deep understanding of disease biology and industry-leading technology prope","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-present-upcoming-investor-conferences-120500533.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2513744949","title":"The Zacks Analyst Blog Highlights Merck, Sanofi, Regeneron and Ionis","url":"https://stock-news.laohu8.com/highlight/detail?id=2513744949","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513744949?lang=en_us&edition=fundamental","pubTime":"2025-02-24 17:46","pubTimestamp":1740390360,"startTime":"0","endTime":"0","summary":"Chicago, IL – February 24, 2025 – Zacks.com announces the list of stocks featured in the Analyst Blog. Every day the Zacks Equity Research analysts discuss the latest news and events impacting stocks and the financial markets. Stocks recently featured in the blog include: Merck MRK, Sanofi SNY, Regeneron REGN and Ionis Pharmaceuticals IONS.Pharma Stock Roundup: EU Nod to Key Drug and Q4 Earnings Results. This week, the European Commission granted approval to Merck’s novel HIF-2α inhibitor, Welireg, for two indications. The FDA granted priority review to a supplemental biologics license application  seeking approval of Sanofi and Regeneron’s blockbuster drug, Dupixent, for a new indication, bullous pemphigoid. Ionis Pharmaceuticals announced its fourth-quarter and full-year 2024 results.Here's a recap of the week’s most important stories.EU Approval to Merck’s Welireg for Two Indications. Dupixent is currently approved in several countries, including the United States and EU, for six ty","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/zacks-analyst-blog-highlights-merck-094600312.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BFTCPJ56.SGD","LU0070302665.USD","LU0985320562.USD","IE0002141913.USD","LU1066051498.USD","LU0320765489.SGD","SGXZ57979304.SGD","LU2023250504.SGD","IE00BBT3K403.USD","LU1057294990.SGD","LU1430594728.SGD","REGN","SG9999015358.SGD","LU2468319806.SGD","LU1989772840.SGD","SG9999014559.SGD","LU0265550359.USD","LU0965509010.AUD","LU1162221912.USD","IONS","LU1585245621.USD","LU1116320901.HKD","LU2361044949.HKD","LU1989772923.USD","LU0106261372.USD","LU0234572021.USD","LU1934455863.HKD","LU1941712264.USD","MRK","LU1929549753.HKD","SG9999014575.USD","LU0265550946.USD","LU1093756168.USD","LU0006306889.USD","SG9999001440.SGD","LU1941712348.USD","SNY","LU0058720904.USD","LU2089984988.USD","LU0889565916.HKD","LU1934455277.USD","SNYNF","BK4007","LU2362541513.USD","LU2112291526.USD","LU0320765646.SGD","LU2237438978.USD","LU1066051225.USD","LU1989771016.USD","LU1699723380.USD"],"gpt_icon":0},{"id":"2513628734","title":"Optimistic Future Outlook for Ionis Pharmaceuticals Driven by Robust Growth and Strategic Initiatives","url":"https://stock-news.laohu8.com/highlight/detail?id=2513628734","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513628734?lang=en_us&edition=fundamental","pubTime":"2025-02-23 19:06","pubTimestamp":1740308802,"startTime":"0","endTime":"0","summary":"Leerink Partners analyst Mani Foroohar has maintained their bullish stance on IONS stock, giving a Buy rating on February 20. Mani Foroohar has giv...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-future-outlook-for-ionis-pharmaceuticals-driven-by-robust-growth-and-strategic-initiatives?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-future-outlook-for-ionis-pharmaceuticals-driven-by-robust-growth-and-strategic-initiatives?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2513941342","title":"Ionis Pharmaceuticals price target lowered to $60 from $61 at Raymond James","url":"https://stock-news.laohu8.com/highlight/detail?id=2513941342","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513941342?lang=en_us&edition=fundamental","pubTime":"2025-02-21 22:35","pubTimestamp":1740148535,"startTime":"0","endTime":"0","summary":"Raymond James lowered the firm’s price target on Ionis Pharmaceuticals  to $60 from $61 and keeps a Strong Buy rating on the shares. Ionis beat nicely in Q4, and the 2025 floor guidance for revenue and operating loss appears reasonable as Ionis transitions to more of a commercial story, the analyst tells investors in a research note.Discover the Best Stocks and Maximize Your Portfolio:. See what stocks are receiving strong buy ratings from top-rated analysts.Filter, analyze, and streamline your search for investment opportunities with  TipRanks’ Stock Screener.Ionis Pharmaceuticals: Hold Rating Amid Revenue Growth, Competitive Pressures, and Delayed Catalysts. Ionis Pharmaceuticals: Balancing Strong R&D Revenues with Market Challenges – Hold Rating Justified","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-price-target-lowered-143535885.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-price-target-lowered-143535885.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","RJF"],"gpt_icon":0},{"id":"2513291467","title":"Pharma Stock Roundup: EU Nod to MRK's Welireg, IONS' Q4 Results & More","url":"https://stock-news.laohu8.com/highlight/detail?id=2513291467","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513291467?lang=en_us&edition=fundamental","pubTime":"2025-02-21 21:41","pubTimestamp":1740145260,"startTime":"0","endTime":"0","summary":"This week, the European Commission granted approval to Merck’s MRK novel HIF-2α inhibitor, Welireg, for two indications. The FDA granted priority review to a supplemental biologics license application  seeking approval of Sanofi SNY and Regeneron’s REGN blockbuster drug, Dupixent, for a new indication, bullous pemphigoid. Ionis Pharmaceuticals IONS announced its fourth-quarter and full-year 2024 results.Here's a recap of the week’s most important stories.IONS reported better-than-expected top and bottom-line numbers for the fourth quarter. Its loss of 66 cents per share was narrower than the Zacks Consensus Estimate of a loss of $1.12 per share. Total revenues of $227 million beat the Zacks Consensus Estimate of $137.5 million. However, revenues declined 30.2% year over year. Commercial revenues were $86 million in the fourth quarter, up 8.9% year over year. R&D revenues declined 42.7% year over year to $141 million.EU Approval to Merck’s Welireg for Two Indications. The NYSE ARCA Phar","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pharma-stock-roundup-eu-nod-134100358.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0965509283.SGD","BK4533","SG9999001440.SGD","LU0070302665.USD","LU0320765489.SGD","LU0823416689.USD","LU2361045086.USD","IE00BLSP4452.SGD","LU0985320562.USD","SG9999015358.SGD","LU1430594728.SGD","LU1066051225.USD","IE00B2B36J28.USD","IONS","LU1061106388.HKD","BK4516","SG9999002232.USD","SG9999013999.USD","SG9999014559.SGD","LU0053666078.USD","LU1023059063.AUD","LU2362541273.HKD","LU1066051498.USD","SGXZ57979304.SGD","LU2023250843.SGD","LU2112291526.USD","LU1934455863.HKD","LU0965509010.AUD","MRK","LU1585245621.USD","LU1934455194.USD","LU0965509101.SGD","BK4588","LU0203345920.USD","LU2361044949.HKD","LU0266013472.USD","LU0882574055.USD","LU1929549753.HKD","LU2237438978.USD","SNY","LU1162221912.USD","LU1934455277.USD","BK4156","REGN","SG9999014542.SGD","LU0106261372.USD","SG9999001176.USD","SG9999014575.USD","IE00BBT3K403.USD"],"gpt_icon":0},{"id":"2513344265","title":"Ionis Pharmaceuticals Inc : Bernstein Cuts Target Price to $43 From $51","url":"https://stock-news.laohu8.com/highlight/detail?id=2513344265","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2513344265?lang=en_us&edition=fundamental","pubTime":"2025-02-21 19:03","pubTimestamp":1740135834,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250221:nFWN3PC10J:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2512449520","title":"BRIEF-New Positive Donidalorsen Data To Be Presented At Aaaai/Wao Joint Congress","url":"https://stock-news.laohu8.com/highlight/detail?id=2512449520","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512449520?lang=en_us&edition=fundamental","pubTime":"2025-02-20 20:15","pubTimestamp":1740053729,"startTime":"0","endTime":"0","summary":"BRIEF-New Positive Donidalorsen Data To Be Presented At Aaaai/Wao Joint CongressFeb 20 (Reuters) - Ionis Pharmaceuticals Inc IONS.O:NEW POSITIVE DONIDALORSEN DATA TO BE PRESENTED AT AAAAI/WAO JOINT CO","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250220:nTUA4PVSWX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"gpt_icon":0},{"id":"2512466764","title":"New Positive Donidalorsen Data to Be Presented at Aaaai/Wao Joint Congress Highlight Sustained Hae Attack Rate Reduction and Disease Control","url":"https://stock-news.laohu8.com/highlight/detail?id=2512466764","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512466764?lang=en_us&edition=fundamental","pubTime":"2025-02-20 20:00","pubTimestamp":1740052801,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250220:nTUA4PVSWX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2512464874","title":"Ionis Pharmaceuticals Full Year 2024 Earnings: Beats Expectations","url":"https://stock-news.laohu8.com/highlight/detail?id=2512464874","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512464874?lang=en_us&edition=fundamental","pubTime":"2025-02-20 19:45","pubTimestamp":1740051950,"startTime":"0","endTime":"0","summary":"NasdaqGS:IONS Earnings and Revenue Growth February 20th 2025. All figures shown in the chart above are for the trailing 12 month  period. Revenue exceeded analyst estimates by 14%. Earnings per share  also surpassed analyst estimates by 13%.Looking ahead, revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 21% growth forecast for the Biotechs industry in the US.The company's shares are up 3.1% from a week ago.We don't want to rain on the parade too much, but we did also find 2 warning signs for Ionis Pharmaceuticals that you need to be mindful of.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-full-2024-earnings-114550524.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2512128674","title":"Ionis Pharmaceuticals Price Target Maintained With a $60.00/Share by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2512128674","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512128674?lang=en_us&edition=fundamental","pubTime":"2025-02-20 18:11","pubTimestamp":1740046260,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IONS/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 20, 2025 05:11 ET (10:11 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2512414696","title":"Barclays Remains a Hold on Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2512414696","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512414696?lang=en_us&edition=fundamental","pubTime":"2025-02-20 17:47","pubTimestamp":1740044853,"startTime":"0","endTime":"0","summary":"In a report released today, Gena Wang from Barclays maintained a Hold rating on Ionis Pharmaceuticals (IONS – Research Report), with a price target...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/barclays-remains-a-hold-on-ionis-pharmaceuticals-ions-3?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/barclays-remains-a-hold-on-ionis-pharmaceuticals-ions-3?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","IONS"],"gpt_icon":0},{"id":"2512558419","title":"Q4 2024 Ionis Pharmaceuticals Inc Earnings Call","url":"https://stock-news.laohu8.com/highlight/detail?id=2512558419","media":"Thomson Reuters StreetEvents","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512558419?lang=en_us&edition=fundamental","pubTime":"2025-02-20 17:16","pubTimestamp":1740042977,"startTime":"0","endTime":"0","summary":"Wade Walke; Senior Vice President, Investor Relations; Ionis Pharmaceuticals Inc. Brett Monia; Chief Executive Officer, Director; Ionis Pharmaceuticals Inc. Kyle Jenne; Executive Vice President - commercial; Ionis Pharmaceuticals Inc. Richard Geary; Executive Vice President, Chief Development Officer; Ionis Pharmaceuticals Inc. Elizabeth Hougen; Chief Financial Officer, Executive Vice President - Finance; Ionis Pharmaceuticals Inc. Eugene Schneider; Executive Vice President, Chief Clinical Development Officer; Ionis Pharmaceuticals Inc. Good morning, and welcome to Ionis' fourth-quarter and full-year 2024 financial results conference call. As a reminder, this call is being recorded.At this time, I would like to turn the call over to Wade Walke, Senior Vice President of Investor Relations, to lead the call. Please begin.Thanks, Wade. Good morning, everyone, and thank you for joining us on today's call. As we begin a new year, I'm thrilled to share that Ionis has begun a new chapter as a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/q4-2024-ionis-pharmaceuticals-inc-091617222.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","AZN"],"gpt_icon":0},{"id":"2512494506","title":"Ionis Pharmaceuticals Inc (IONS) Q4 2024 Earnings Call Highlights: Surpassing Revenue ...","url":"https://stock-news.laohu8.com/highlight/detail?id=2512494506","media":"GuruFocus.com","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512494506?lang=en_us&edition=fundamental","pubTime":"2025-02-20 15:10","pubTimestamp":1740035453,"startTime":"0","endTime":"0","summary":"Non-GAAP Operating Loss: $345 million, a significant improvement compared to 2024 guidance.Total Revenue: $705 million, exceeding 2024 guidance by more than $130 million.WAINUA Product Sales: $85 million for the year, with $20 million in royalties.Fourth Quarter WAINUA Growth: 84% increase in product revenue compared to the third quarter.Sales and Marketing Expenses: Increased by 12% year-over-year, reflecting investments in TRYNGOLZA and Donidalorsen launches.Projected 2025 Revenue: More than $600 million, with a shift towards commercial revenue.Projected 2025 Operating Expenses: Expected to increase in the high single-digit percentage range compared to last year.Projected 2025 Non-GAAP Operating Loss: Less than $495 million.Projected Year-End Cash and Investments: Approximately $1.7 billion.GuruFocus has detected 3 Warning Signs with IONS.Ionis Pharmaceuticals Inc  successfully launched TRYNGOLZA, their first independently launched medicine, for familial chylomicronemia syndrome , wi","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ionis-pharmaceuticals-inc-ions-q4-071053344.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS"],"gpt_icon":0},{"id":"2512557184","title":"Optimistic Buy Rating for Ionis Pharmaceuticals Driven by Promising Financial Outlook and Strategic Advancements","url":"https://stock-news.laohu8.com/highlight/detail?id=2512557184","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512557184?lang=en_us&edition=fundamental","pubTime":"2025-02-20 07:05","pubTimestamp":1740006316,"startTime":"0","endTime":"0","summary":"Analyst Yaron Werber of TD Cowen reiterated a Buy rating on Ionis Pharmaceuticals (IONS – Research Report), retaining the price target of $59.00. Y...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-buy-rating-for-ionis-pharmaceuticals-driven-by-promising-financial-outlook-and-strategic-advancements?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-buy-rating-for-ionis-pharmaceuticals-driven-by-promising-financial-outlook-and-strategic-advancements?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"gpt_icon":0},{"id":"2512243627","title":"Ionis Pharmaceuticals price target lowered to $38 from $45 at Stifel","url":"https://stock-news.laohu8.com/highlight/detail?id=2512243627","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512243627?lang=en_us&edition=fundamental","pubTime":"2025-02-20 04:00","pubTimestamp":1739995226,"startTime":"0","endTime":"0","summary":"Stifel analyst Paul Matteis lowered the firm’s price target on Ionis Pharmaceuticals (IONS) to $38 from $45 and keeps a Hold rating on the shares f...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-38-from-45-at-stifel?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-38-from-45-at-stifel?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS","SF"],"gpt_icon":0},{"id":"2512248781","title":"Ionis Pharmaceuticals Q4 Revenue Growth Exceeds Guidance, Forecasts Over $600 Million In 2025 Sales","url":"https://stock-news.laohu8.com/highlight/detail?id=2512248781","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512248781?lang=en_us&edition=fundamental","pubTime":"2025-02-20 01:11","pubTimestamp":1739985113,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals posted a smaller-than-expected Q4 loss and exceeded revenue estimates. The company projects 2025 revenue of over $600 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/25/02/43818962/ionis-pharmaceuticals-says-2024-revenue-exceeds-guidance-on-sales-from-diverse-sources-forecasts-over-600-million-in-2025-sales","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"gpt_icon":0},{"id":"2512892485","title":"Ionis Pharmaceuticals trading resumes","url":"https://stock-news.laohu8.com/highlight/detail?id=2512892485","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512892485?lang=en_us&edition=fundamental","pubTime":"2025-02-19 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