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XTALPI

11.220

-0.390-3.36%

Volume:73.59M

Turnover:838.70M

Market Cap:48.28B

PE:-13.08

High:11.670

Open:11.600

Low:11.100

Close:11.610

52wk High:15.120

52wk Low:3.050

Shares:4.30B

HK Float Shares:4.30B

Volume Ratio:0.78

T/O Rate:1.71%

Dividend:- -

Dividend Rate:- -

EPS(LYR):-0.858

ROE:-3.61%

ROA:-3.35%

PB:6.32

PE(LYR):-13.08

PS:64.97

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Overview Company News Filings

Hong Kong Stocks Movement | XTALPI (02228) Surges Over 8% Again on AI Drug Development Partnership with Hangzhou Bio-Sincerity and Strategic Talks with China Merchants Group

Hong Kong Stocks Movement | XTALPI (02228) Surged Nearly 7% in Morning Trading as Company Signs Cooperation Agreement with Hangzhou Bio-Sincerity Pharma-Tech for Joint AI Drug Development

XTALPI Rises Over 6% in Morning Trading as Company Assists SmartEngine Biotech's New Drug in Obtaining Clinical Trial Approval

HK Movers | Biotech Stocks Jump With Biocytogen up 11%

Tiger Newspress

XtalPi Holdings (SEHK:2228) Advances AI-Driven Cancer Therapy With Regulatory Clearance

Simply Wall St.

BRIEF-XtalPi & PharmaEngine Hit Milestone as PRMT5 Inhibitor PEP08 Gets Trial Nod

Xtalpi AI Drug Discovery Collaboration Reaches Milestone as Pharmaengine's Novel Prmt5 Inhibitor Pep08 Receives Clinical Trial Approvals

THOMSON REUTERS

XTALPI (02228) Facilitates PharmaEngine's Next-Generation "Synthetic Lethality" Drug to Receive Clinical Trial Approval, Marking Another AI Drug Discovery Milestone

XTALPI Visits Guangzhou Pharma Group for Research Exchange, Exploring New Cooperation Opportunities

XtalPi Holdings Completes HK$2,629.8 Million Private Placement of New Shares Under General Mandate

XtalPi Eyeing HK$2.7 Billion via Share Sale

MT Newswires Live

Stock Track | XTALPI Soars 5.17% on HK$2.63 Billion Share Placement Plan

BUZZ-HK-listed XtalPi falls most in 4 weeks on discounted share sale

Stock Track | XTALPI Plummets 5.37% as Company Announces HK$2.63 Billion Share Placement Plan

BRIEF-XtalPi Holdings To Place Up To 285.9 Million Shares

Hong Kong Stock Concept Tracking | Tech Giants Pour in Investments as AI Drug Development Commercialization Accelerates (With Concept Stocks)

XTALPI (02228) Plans Share Placement at HK$9.28 Per Share, Seeking to Raise Up to HK$2.63 Billion Net

Xtalpi Holdings Ltd - to Place up to 285.9 Mln Shares at HK$9.28 per Share

THOMSON REUTERS

Stock Track | XTALPI Plummets 5.16% Despite Turning Profit in First Half of 2025

XtalPi Turns to H1 Profit Amid 404% Revenue Boost

MT Newswires Live

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Biocytogen Pharmaceuticals rose 11%, Duality Biotherapeutics rose 5%, Clover Biopharmaceuticals and XtalPi Holdings rose 4%, RemeGen rose 3%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"7f57c21d2de1ad5f8126acab611ae5a5","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["09926","02315","02228","09606","09995","06160","02197"],"gpt_icon":0},{"id":"2566652935","title":"XtalPi Holdings (SEHK:2228) Advances AI-Driven Cancer Therapy With Regulatory Clearance","url":"https://stock-news.laohu8.com/highlight/detail?id=2566652935","media":"Simply Wall St.","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2566652935?lang=en_us&edition=fundamental","pubTime":"2025-09-11 04:18","pubTimestamp":1757535506,"startTime":"0","endTime":"0","summary":"XtalPi Holdings (SEHK:2228) recently announced a significant milestone as its next-generation PRMT5 inhibitor, PEP08, received regulatory approvals to begin Phase 1 clinical trials for solid tumors. This development underscores the company's advanced capabilities in drug discovery, likely contributing to the impressive 65% rise in its stock price over the last quarter. Alongside broader tech market gains, highlighted by the S&P 500 and Nasdaq reaching new highs, XtalPi's earnings reports...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-2228/xtalpi-holdings-shares/news/xtalpi-holdings-sehk2228-advances-ai-driven-cancer-therapy-w","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-2228/xtalpi-holdings-shares/news/xtalpi-holdings-sehk2228-advances-ai-driven-cancer-therapy-w","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK1141","BK1617","02228"],"gpt_icon":1},{"id":"2566697124","title":"BRIEF-XtalPi & PharmaEngine Hit Milestone as PRMT5 Inhibitor PEP08 Gets Trial Nod","url":"https://stock-news.laohu8.com/highlight/detail?id=2566697124","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2566697124?lang=en_us&edition=fundamental","pubTime":"2025-09-09 20:44","pubTimestamp":1757421854,"startTime":"0","endTime":"0","summary":"BRIEF-XtalPi & PharmaEngine Hit Milestone as PRMT5 Inhibitor PEP08 Gets Trial NodSept 9 (Reuters) - XtalPi Holdings Ltd 2228.HK:XTALPI AI DRUG DISCOVERY COLLABORATION REACHES MILESTONE AS PHARMAENGINE","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250909:nTUA6WJLN4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["02228","BK1617","BK1141"],"gpt_icon":0},{"id":"2566969796","title":"Xtalpi AI Drug Discovery Collaboration Reaches Milestone as Pharmaengine's Novel Prmt5 Inhibitor Pep08 Receives Clinical Trial Approvals","url":"https://stock-news.laohu8.com/highlight/detail?id=2566969796","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2566969796?lang=en_us&edition=fundamental","pubTime":"2025-09-09 20:39","pubTimestamp":1757421556,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250909:nTUA6WJLN4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK1141","BK1617","02228"],"gpt_icon":0},{"id":"1145874920","title":"XTALPI (02228) Facilitates PharmaEngine's Next-Generation \"Synthetic Lethality\" Drug to Receive Clinical Trial Approval, Marking Another AI Drug Discovery Milestone","url":"https://stock-news.laohu8.com/highlight/detail?id=1145874920","media":"Stock News","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1145874920?lang=en_us&edition=fundamental","pubTime":"2025-09-08 09:32","pubTimestamp":1757295146,"startTime":"0","endTime":"0","summary":"XTALPI (02228) announced today that PEP08, a next-generation PRMT5 inhibitor discovered with its assistance for PharmaEngine, Inc., has achieved a significant clinical development milestone. PEP08...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1191","BK1141","01477","BK1574","BK1617","02228"],"gpt_icon":1},{"id":"1113315681","title":"XTALPI Visits Guangzhou Pharma Group for Research Exchange, Exploring New Cooperation Opportunities","url":"https://stock-news.laohu8.com/highlight/detail?id=1113315681","media":"Deep News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1113315681?lang=en_us&edition=fundamental","pubTime":"2025-09-04 23:10","pubTimestamp":1756998642,"startTime":"0","endTime":"0","summary":"On September 3rd, Ma Jian, Co-founder and CEO of XTALPI, led a delegation to visit Guangzhou Pharma Group. Chen Jiehui, Deputy Party Secretary, Vice Chairman, and General Manager of Guangzhou Pharma...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1141","BK1617","162414","02228"],"gpt_icon":1},{"id":"2564320121","title":"XtalPi Holdings Completes HK$2,629.8 Million Private Placement of New Shares Under General Mandate","url":"https://stock-news.laohu8.com/highlight/detail?id=2564320121","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2564320121?lang=en_us&edition=fundamental","pubTime":"2025-09-04 17:32","pubTimestamp":1756978378,"startTime":"0","endTime":"0","summary":"XtalPi Holdings Limited has announced the completion of a placement of new shares under a general mandate. The placement involved not less than six placees at a price of HK$9.28 per share, accounting for approximately 6.64% of the company's enlarged issued share capital. The total gross proceeds from the placement amounted to approximately HK$2,653.3 million, with net proceeds of around HK$2,629.8 million after deducting applicable costs and expenses. The company plans to use the net proceeds for business development, market expansion, and investment opportunities, with any unused funds potentially held in short-term deposits or used to purchase short-term wealth management products.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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Before trading hours, XTALPI...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["02228"],"gpt_icon":1},{"id":"2563091258","title":"BUZZ-HK-listed XtalPi falls most in 4 weeks on discounted share sale","url":"https://stock-news.laohu8.com/highlight/detail?id=2563091258","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2563091258?lang=en_us&edition=fundamental","pubTime":"2025-08-29 10:31","pubTimestamp":1756434663,"startTime":"0","endTime":"0","summary":"BUZZ-HK-listed XtalPi falls most in 4 weeks on discounted share sale** Shares of XtalPi Holdings 2228.HK fall 5.5% to HK$9.51, their biggest intraday pct drop since August 1** Stock hit its lowest since August 22, on track for fourth straight session of decline, if losses hold ** The intelligent robotics and drug discovery solutions provider plans sale of 285.92 million new shares, or 6.64% of the enlarged share capital, in a share placement programme, raising HK$2.65 billion  for product iterations, upgrades and commercialisation ** The new shares will be issued at HK$9.28 each, representing a 7.75% discount to Thursday's close of HK$10.06 per share** Hong Kong's healthcare index .HSCIH rises 2.1%, benchmark Hang Seng Index .HSI gains 0.7%** YTD, stock up 61.9%  ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250829:nL4N3UL04N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["02228","BK1617","BK1141"],"gpt_icon":1},{"id":"1133927366","title":"Stock Track | XTALPI Plummets 5.37% as Company Announces HK$2.63 Billion Share Placement Plan","url":"https://stock-news.laohu8.com/highlight/detail?id=1133927366","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1133927366?lang=en_us&edition=fundamental","pubTime":"2025-08-29 09:36","pubTimestamp":1756431374,"startTime":"0","endTime":"0","summary":"XTALPI (02228) saw its stock price plummet by 5.37% in early trading on Friday, following the company's announcement of a significant share placement plan. The sharp decline came as investors reacted...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["02228"],"gpt_icon":1},{"id":"2563096456","title":"BRIEF-XtalPi Holdings To Place Up To 285.9 Million Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2563096456","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2563096456?lang=en_us&edition=fundamental","pubTime":"2025-08-29 09:32","pubTimestamp":1756431123,"startTime":"0","endTime":"0","summary":"BRIEF-XtalPi Holdings To Place Up To 285.9 Million SharesAug 29 (Reuters) - XtalPi Holdings Ltd 2228.HK:TO PLACE UP TO 285.9 MILLION SHARES AT HK$9.28 PER SHAREFurther company coverage: 2228.HK ((Reuters.Briefs@thomsonreuters.com;))","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250829:nFWN3UK20E:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1617","BK1141","02228"],"gpt_icon":0},{"id":"1117299590","title":"Hong Kong Stock Concept Tracking | Tech Giants Pour in Investments as AI Drug Development Commercialization Accelerates (With Concept Stocks)","url":"https://stock-news.laohu8.com/highlight/detail?id=1117299590","media":"Stock News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1117299590?lang=en_us&edition=fundamental","pubTime":"2025-08-29 08:32","pubTimestamp":1756427558,"startTime":"0","endTime":"0","summary":"SandboxAQ, an AI startup spun off from Alphabet (GOOGL.US) and strategically backed by NVIDIA (NVDA.US), officially released a large-scale synthetic dataset on June 18 local time, aimed at...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["YANG","XMAG","MSFT","AMZN","HSCEI","GOOG","BK4614","07226","BK1191","BK1576","BK1141","BK1574","META","01477","AAPL","NVDA","HSTECH","01873","BK1617","02228"],"gpt_icon":1},{"id":"1187492046","title":"XTALPI (02228) Plans Share Placement at HK$9.28 Per Share, Seeking to Raise Up to HK$2.63 Billion Net","url":"https://stock-news.laohu8.com/highlight/detail?id=1187492046","media":"Stock News","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1187492046?lang=en_us&edition=fundamental","pubTime":"2025-08-29 08:26","pubTimestamp":1756427173,"startTime":"0","endTime":"0","summary":"XTALPI (02228) announced that on August 29, 2025 (before trading hours), the company entered into a placing agreement with placing agents to place up to approximately 286 million placing shares...","market":"sh","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1617","02228","BK1141"],"gpt_icon":1},{"id":"2563098203","title":"Xtalpi Holdings Ltd - 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