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Akero Therapeutics

44.87

-0.4400-0.97%

Post-market: 44.870.00000.00%17:20 EDT

Volume:1.21M

Turnover:54.60M

Market Cap:3.57B

PE:-11.95

High:46.47

Open:45.51

Low:44.08

Close:45.31

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Overview Company News Filings

S&P 500 Falls Over 100 Points; Dada Nexus Shares Spike Higher

Madrigal dip on Akero data a buying opportunity, says Evercore ISI

Top Midday Gainers

MT Newswires Live

Akero's Stock Skyrockets 112% After Game-Changing Liver Drug Data

Efruxifermin’s Breakthrough in Cirrhosis Reversal Fuels Buy Rating for Akero Therapeutics

Top Stock Movers Now: Nvidia, Broadcom, Vistra, and More

H.C. Wainwright upgrades Akero target after ‘ground-breaking’ data

Akero Therapeutics Stock Doubles on Liver Disease Drug Trial Results

Akero Therapeutics Shares Surge 106% as Phase 2b Study Shows Significant Cirrhosis Reversal

Akero Therapeutics Stock Doubles on Liver Data -- Barrons.com

Nasdaq Dips 3%; Chicago Fed National Activity Index Rises In December

Sector Update: Health Care Stocks Mixed Premarket Monday

MT Newswires Live

Chinese AI Platform Fuels Jitters on Wall Street, Driving Premarket Losses for US Equity Futures

MT Newswires Live

Liver Disease-Focused Akero Therapeutics Stock Soars Over 100% On Monday - Here's Why

Akero Therapeutics MASH data ‘best-case-scenario,’ says Citi

Exchange-Traded Funds, Equity Futures Lower Pre-Bell Monday as China's DeepSeek Disrupts Tech Sector

MT Newswires Live

Akero Therapeutics Says Phase 2b Efruxifermin Study Shows 'Statistically Significant' Reversal of Cirrhosis

MT Newswires Live

Akero soars as drug shows it reverses scarring in liver disease patients

Akero Therapeutics Shares Double After Positive Study Results for Efruxifermin

Akero shares double after preliminary results from mid-stage trial for liver disease drug

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i...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/madrigal-dip-on-akero-data-a-buying-opportunity-says-evercore-isi?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/madrigal-dip-on-akero-data-a-buying-opportunity-says-evercore-isi?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","AKRO","BK4588","BK4505","BK4585"],"gpt_icon":0},{"id":"2506258320","title":"Top Midday Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2506258320","media":"MT Newswires 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cirrhosis caused by metabolic dysfunction-associated steatohepatitis, or MASH.Shares surged more than 91% as intraday trading volume catapulted to over 11.7 million from a daily average of about 723,000.Price: 1.75, Change: 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Stock Skyrockets 112% After Game-Changing Liver Drug Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2506130058","media":"GuruFocus.com","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506130058?lang=en_us&edition=fundamental","pubTime":"2025-01-28 01:13","pubTimestamp":1737998014,"startTime":"0","endTime":"0","summary":"Akero Therapeutics  just flipped the script on the MASH treatment market. Shares surged 112% this morning after jaw-dropping Phase 2b data showed its drug, efruxifermin , could actually reverse cirrhosisa condition long believed to be irreversible. The breakthrough crushed fears that Eli Lilly and Novo Nordisk's GLP-1 drugs would dominate the space, reigniting confidence in targeted therapies. With 39% of patients in the trial showing fibrosis reversalmore than double the placebo groupthe data isn't just good, it's game-changing. Jefferies wasted no time reaffirming its Buy rating with a $50 price target, while some analysts think Akero could hit $75 if Phase 3 trials confirm the results.GuruFocus has detected 3 Warning Signs with AKRO.Meanwhile, not every biotech is celebrating. Keros Therapeutics just hit a roadblock, pausing parts of its Phase 2 TROPOS trial due to unexpected safety concerns. Biotech stocks are a rollercoaster, but Akero's stunning data is proof that when a breakthr","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/akeros-stock-skyrockets-112-game-171334490.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","BK4588","ETNB","BK4123","AKRO","BK4505","EFX","BK4139"],"gpt_icon":0},{"id":"2506307589","title":"Efruxifermin’s Breakthrough in Cirrhosis Reversal Fuels Buy Rating for Akero Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2506307589","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506307589?lang=en_us&edition=fundamental","pubTime":"2025-01-28 00:55","pubTimestamp":1737996911,"startTime":"0","endTime":"0","summary":"Analyst Rami Katkhuda from LifeSci Capital maintained a Buy rating on Akero Therapeutics (AKRO – Research Report) and increased the price target to...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/efruxifermins-breakthrough-in-cirrhosis-reversal-fuels-buy-rating-for-akero-therapeutics?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/efruxifermins-breakthrough-in-cirrhosis-reversal-fuels-buy-rating-for-akero-therapeutics?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["AKRO"],"gpt_icon":0},{"id":"2506497300","title":"Top Stock Movers Now: Nvidia, Broadcom, Vistra, and More","url":"https://stock-news.laohu8.com/highlight/detail?id=2506497300","media":"Investopedia","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506497300?lang=en_us&edition=fundamental","pubTime":"2025-01-28 00:50","pubTimestamp":1737996607,"startTime":"0","endTime":"0","summary":"The S&P 500 and Nasdaq plunged at midday when Chinese artificial intelligence startup DeepSeek shook up the sector with a lower-cost large language model.Shares of chip makers, power providers, and other AI-related companies tumbled.AT&T boosted the number of subscribers, helping the telcom giant to beat profit and sales estimates.The S&P 500 and Nasdaq sank at midday, dragged down by tech shares after Chinese artificial intelligence  startup DeepSeek announced it had developed an AI large language model  at a much lower cost. The Nasdaq plunged 3%, and the S&P 500 slid 2%.The Dow Jones Industrial Average was down slightly.Shares of AI chipmakers were especially hard hit, with Nvidia , Broadcom , and Micron Technology  shares tumbling.Also hammered were power providers, such as Vistra  and Constellation Energy , which have been benefiting from expected demand for electricity to run AI data centers.Apple  shares advanced as soaring demand sent DeepSeek to the top of the company's App St","market":"fut","thumbnail":"https://www.investopedia.com/thmb/r6dTlNQ2tcg2jjqnKTanpo0BL9M=/6000x4000/filters:no_upscale():max_bytes(150000):strip_icc()/GettyImages-2195628308-6ba2168bcb784ca8a7748e34e73633c7.jpg","type":0,"news_type":0,"thumbnails":["https://www.investopedia.com/thmb/r6dTlNQ2tcg2jjqnKTanpo0BL9M=/6000x4000/filters:no_upscale():max_bytes(150000):strip_icc()/GettyImages-2195628308-6ba2168bcb784ca8a7748e34e73633c7.jpg"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.investopedia.com/top-stock-movers-now-nvidia-broadcom-vistra-and-more-8780883","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"investopedia_highlight","symbols":["NVDU","LU0466842654.USD","NVDS.UK","VST","LU0345770993.USD","SSO","LU1974910355.USD","NVD2.UK","IVV","T","LU0719512351.SGD","MACW.SI","NVD","SPY","LU1804176565.USD","NVDS","CEG","IE0004086264.USD","GOOGL","SG9999018865.SGD","VOO","2NVD.UK","AAPL","AVGO","NVDA","NVIW.SI","OEF","UPRO","NVDD","ESmain",".SPX","AVGOP","MSFT","SPXU","SH","LU1670710588.SGD","LU0289941410.SGD","NVD3.UK","SDS","NQmain","SNVD.UK","IE00BN8TJ469.HKD","NVDY","NVDX","LU0786609619.USD","OEX","3NVD.UK","MU","AKRO"],"gpt_icon":1},{"id":"2506834307","title":"H.C. Wainwright upgrades Akero target after ‘ground-breaking’ data","url":"https://stock-news.laohu8.com/highlight/detail?id=2506834307","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506834307?lang=en_us&edition=fundamental","pubTime":"2025-01-28 00:45","pubTimestamp":1737996315,"startTime":"0","endTime":"0","summary":"H.C. Wainwright raised the firm’s price target on Akero Therapeutics (AKRO) to $72 from $50 and keeps a Buy rating on the shares after the company ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/h-c-wainwright-upgrades-akero-target-after-ground-breaking-data?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/h-c-wainwright-upgrades-akero-target-after-ground-breaking-data?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["AKRO","BK4505","BK4585","BK4588","BK4139"],"gpt_icon":0},{"id":"2506552588","title":"Akero Therapeutics Stock Doubles on Liver Disease Drug Trial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2506552588","media":"Investopedia","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506552588?lang=en_us&edition=fundamental","pubTime":"2025-01-28 00:27","pubTimestamp":1737995257,"startTime":"0","endTime":"0","summary":"Akero Therapeutics shares traded near their all-time high as the drugmaker reported positive results in a study of its treatment for liver disease.The drug, known as EFX, helped reverse cirrhosis of the liver in patients with metabolic dysfunction-associated steatohepatitis .CEO Dr. Andrew Cheng said EFX has \"transformational potential\" in fighting the disease.Shares of Akero Therapeutics  doubled Monday when the pharmaceutical firm that focuses on metabolic illnesses reported positive results from a study of its experimental treatment for liver disease.The company said a 96-week Phase 2b study ofthose afflicted with cirrhosis caused by metabolic dysfunction-associated steatohepatitis  and given a 50mg dosage of its drug efruxifermin  showed that 39% experienced reversal of cirrhosis with no worsening of MASH. That compares to just 15% of those given placebo.Akero noted that a subgroup of patients who were not on GLP-1 weight-loss medicines, such as Novo Nordisk's  Wegovy and Eli Lilly","market":"fut","thumbnail":"https://www.investopedia.com/thmb/bjuORyMW_ZCng1ZoL1sKqOvM4Kk=/1779x546/filters:no_upscale():max_bytes(150000):strip_icc()/Akero-logo-color-861f5338b8ed4e4d8e187cf4a1d52d62.png","type":0,"news_type":0,"thumbnails":["https://www.investopedia.com/thmb/bjuORyMW_ZCng1ZoL1sKqOvM4Kk=/1779x546/filters:no_upscale():max_bytes(150000):strip_icc()/Akero-logo-color-861f5338b8ed4e4d8e187cf4a1d52d62.png"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.investopedia.com/akero-therapeutics-stock-doubles-on-liver-disease-drug-trial-results-8780840","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"investopedia_highlight","symbols":["LU1551013342.USD","LU1814569148.SGD","LU2106854487.HKD","LU0820561818.USD","LLY","LU0097036916.USD","BK4585","SG9999014898.SGD","SG9999015945.SGD","BK7104","LU2237443622.USD","BK4533","LU2211815571.USD","LU2361044865.SGD","LU1548497426.USD","LU0820561909.HKD","SGXZ31699556.SGD","BK4123","SG9999014906.USD","LU1061106388.HKD","LU0456855351.SGD","LU2237443895.HKD","LU0198837287.USD","AKRO","LU1035775433.USD","LU1983299246.USD","BK4139","NVO.AU","LU2461242641.AUD","LU1868837300.USD","IE00B2B36J28.USD","LU0882574139.USD","LU1057294990.SGD","LU1712237335.SGD","SG9999015952.SGD","BK4534","LU0109391861.USD","LU1868836757.USD","LU1720051017.SGD","BK4516","LU1551013425.SGD","NVO","IE00BKVL7J92.USD","LU2324357040.USD","LU0238689110.USD","LU2491049909.HKD","EFX","LU0943347566.SGD","LU0354030438.USD","LU0289739699.SGD"],"gpt_icon":1},{"id":"2506304650","title":"Akero Therapeutics Shares Surge 106% as Phase 2b Study Shows Significant Cirrhosis Reversal","url":"https://stock-news.laohu8.com/highlight/detail?id=2506304650","media":"GuruFocus.com","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506304650?lang=en_us&edition=fundamental","pubTime":"2025-01-28 00:10","pubTimestamp":1737994212,"startTime":"0","endTime":"0","summary":"On Monday, at 10:23 a.m. GMT-5, Akero Therapeutics  saw its stock soar by 106.63%, closing at $54.10, following the release of promising preliminary results from its Phase 2b SYMMETRY study.GuruFocus has detected 3 Warning Signs with AKRO.The Akero statement underlined how well their medicine efruxifermin treats compensated cirrhosis brought on by metabolic dysfunction-associated steatohepatitis.Akero claims that compared to 15 percent of patients on placebo, 39 percent of patients getting a 50-milligram dosage of EFX showed at least a one-stage improvement in liver fibrosis without worsening MASH, according to the SYMMETRY trial reaching the 96-week milestone. Over the placebo group, this reflects a 24 percent larger impact size. Akero claimed a 17 percent advantage in an intent-to- treat analysis, which accounted for all participants by considering missing biopsies as failures, 29 percent of the EFX group exhibited comparable improvements vs 12 percent in the placebo group.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/akero-therapeutics-shares-surge-106-161012426.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4588","BK4139","BK4585","AKRO","BK4505"],"gpt_icon":0},{"id":"2506301314","title":"Akero Therapeutics Stock Doubles on Liver Data -- Barrons.com","url":"https://stock-news.laohu8.com/highlight/detail?id=2506301314","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506301314?lang=en_us&edition=fundamental","pubTime":"2025-01-27 23:57","pubTimestamp":1737993420,"startTime":"0","endTime":"0","summary":"Shares of Akero Therapeutics more than doubled in response to startlingly positive data on its liver drug efruxifermin, which the biotech said reversed liver scarring in patients with advanced cases of the condition known as MASH.The data appeared to slam the door on the idea that the advent of the GLP-1 drugs from Eli Lilly and Novo Nordisk would eliminate demand for drugs specifically intended to treat MASH, or metabolic dysfunction-associated steatohepatitis.Data from Lilly last year had shown that tirzepatide, the drug sold under the brand names Zepbound and Mounjaro, could be an effective treatment for MASH. That sent shares of companies working on MASH drugs tumbling, on the theory that Zepbound and Mounjaro would swallow the market.The new results on Akero's efruxifermin, however, appear to be unprecedented. They point to a significant market opportunity.Compensated cirrhosis can be managed, but isn't generally considered reversible. In Akero's trial, however, 39% of patients 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Dips 3%; Chicago Fed National Activity Index Rises In December","url":"https://stock-news.laohu8.com/highlight/detail?id=2506308445","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506308445?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:43","pubTimestamp":1737989032,"startTime":"0","endTime":"0","summary":" ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/25/01/43233976/nasdaq-dips-3-chicago-fed-national-activity-index-rises-in-december","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NVIW.SI","BK4585","NQmain","USAW.SI","SQQQ","QID","TSYW.SI","IE00BGHQF748.EUR","JG","LU2210150020.SGD","ETNB","QLD","NHLD","USJW.SI","BK4183","BK4112","PSQ","AKRO","BK4139","IE00BKPKM429.USD","BK4584","BK4505","BK4023","BK4588","BK4557","VERU","ALLK","LU2095319765.USD",".IXIC","LU2210149790.SGD","ELAB","IE00B3QW5Z07.USD","IE00B64PRP62.GBP","BK4587","NDAQ","TQQQ","MNQmain"],"gpt_icon":1},{"id":"2506550370","title":"Sector Update: Health Care Stocks Mixed Premarket Monday","url":"https://stock-news.laohu8.com/highlight/detail?id=2506550370","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506550370?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:11","pubTimestamp":1737987112,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed premarket Monday, with The Health Care Select Sector SPDR Fund  up 0.4% and the iShares Biotechnology ETF  0.3% lower.Akero Therapeutics  shares were up over 110% after the company said a phase 2b study of its lead product candidate efruxifermin showed a \"statistically significant\" reversal of compensated cirrhosis caused by metabolic dysfunction-associated steatohepatitis, or MASH.Allakos  stock was down past 73% after the company said its phase 1 trial of AK006 in chronic spontaneous urticaria failed to demonstrate therapeutic efficacy and its development will be terminated immediately.Innate Pharma  shares were up over 7% after the company said it has dosed its first patient in a phase 1 study to investigate the safety and tolerability of IPH4502, an antibody-drug conjugate for the potential treatment of patients with advanced solid tumors known to express Nectin-4.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4505","BK4585","ALLK","BK4588","IPHA","BK4139","IBB","XLV","AKRO","BK4581"],"gpt_icon":0},{"id":"2506377071","title":"Chinese AI Platform Fuels Jitters on Wall Street, Driving Premarket Losses for US Equity Futures","url":"https://stock-news.laohu8.com/highlight/detail?id=2506377071","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506377071?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:03","pubTimestamp":1737986580,"startTime":"0","endTime":"0","summary":"US equity futures dropped ahead of Monday's opening bell, with futures of the technology-heavy Nasdaq Composite leading the losses amid concerns surrounding the artificial intelligence sector.Dow Jone","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NVDS.UK","DOG","SDOW","AMD.AU","03165","LU0171293334.USD","MNQmain","LU2417539215.USD","NVDA","PSQ","MU","NVDS","2NVD.UK","NVD3.UK","AKRO","LU0545039389.USD","AVGO","SQQQ","AMD","NVIW.SI","DXD",".SPX","EQR","NVDD","NVDX","USAW.SI","DDM","NVDU","NQmain",".DJI","LU1861215975.USD","NVDY","LU2133065610.SGD","NVD","UDOW","NVD2.UK","TQQQ","DJX","MSFT","QLD","TSYW.SI",".IXIC","QID","SNVD.UK","ASML","JG","USJW.SI","3NVD.UK"],"gpt_icon":1},{"id":"2506469370","title":"Liver Disease-Focused Akero Therapeutics Stock Soars Over 100% On Monday - Here's Why","url":"https://stock-news.laohu8.com/highlight/detail?id=2506469370","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506469370?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:01","pubTimestamp":1737986519,"startTime":"0","endTime":"0","summary":"On Monday, Akero Therapeutics, Inc. released preliminary topline week 96 results from SYMMETRY Phase 2b study evaluating the efficacy and safety of its lead product candidate efruxifermin  in patients with biopsy-confirmed compensated cirrhosis , Child-Pugh Class A, due to metabolic dysfunction-associated steatohepatitis .Among patients with baseline and week 96 biopsies , 39% of patients treated with 50mg EFX  experienced reversal of cirrhosis with no worsening of MASH, representing a 24% effect size over placebo at 15% .In the Intent to Treat  population , with all missing week 96 biopsies treated as failures, 29% of patients in the 50mg EFX group  experienced reversal of cirrhosis with no worsening of MASH, representing a 17% effect size over placebo at 12% .With more than a doubling of effect size from weeks 36 to 96 in the 50mg group , the SYMMETRY study underscores the benefit of longer EFX treatment for patients with compensated cirrhosis .","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/liver-disease-focused-akero-therapeutics-140159595.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","BK4161","AKRO","BK4139","ITT","BK4505","BK4123","BK4588","EFX","LU0054578231.USD","LU0053671581.USD"],"gpt_icon":0},{"id":"2506337722","title":"Akero Therapeutics MASH data ‘best-case-scenario,’ says Citi","url":"https://stock-news.laohu8.com/highlight/detail?id=2506337722","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506337722?lang=en_us&edition=fundamental","pubTime":"2025-01-27 21:46","pubTimestamp":1737985594,"startTime":"0","endTime":"0","summary":"Citi analyst Jonathan Woo says Akero Therapeutics (AKRO)’ 96-week data update from its SYMMETRY trial of efruxifermin for patients with compensated...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/akero-therapeutics-mash-data-best-case-scenario-says-citi?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/akero-therapeutics-mash-data-best-case-scenario-says-citi?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4505","BK4139","AKRO","BK4585","BK4588"],"gpt_icon":0},{"id":"2506837236","title":"Exchange-Traded Funds, Equity Futures Lower Pre-Bell Monday as China's DeepSeek Disrupts Tech Sector","url":"https://stock-news.laohu8.com/highlight/detail?id=2506837236","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506837236?lang=en_us&edition=fundamental","pubTime":"2025-01-27 21:28","pubTimestamp":1737984504,"startTime":"0","endTime":"0","summary":"The broad market exchange-traded fund SPDR S&P 500 ETF Trust (SPY) was down 2.1% and the actively traded Invesco QQQ Trust (QQQ) fell 4% in Monday's premarket activity, on rising investor concerns ove","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["XSD","EQR","XLV","FAZ","DADA","IYW","EEM","IPK","JG","XLY","GLD","PMR","IYJ","XLI","SOXX","USO","XLP","IGM","IYK","XLF","XRT","BITO","SLV","QQQ","RTH","IYH","AKRO",".IXIC","IGV","XLK","RYAAY",".DJI","FAS","IBB","BAM","DEC","IYE","UNG",".SPX","SPY","VHT","VDC","VIS","XLE","IVV","EXI"],"gpt_icon":1},{"id":"2506371656","title":"Akero Therapeutics Says Phase 2b Efruxifermin Study Shows 'Statistically Significant' Reversal of Cirrhosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2506371656","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506371656?lang=en_us&edition=fundamental","pubTime":"2025-01-27 20:50","pubTimestamp":1737982216,"startTime":"0","endTime":"0","summary":"Akero Therapeutics  said Monday that a phase 2b study of its lead product candidate efruxifermin showed a \"statistically significant\" reversal of compensated cirrhosis caused by metabolic dysfunction-associated steatohepatitis, or MASH.The company said that among patients with baseline and week 96 biopsies, 39% of those treated with efruxifermin showed reversal of cirrhosis without worsening MASH, compared with 15% for the placebo group. In the intent-to-treat group, 29% of patients treated achieved reversal, compared with about 12% for placebo, the company added.Efruxifermin was well-tolerated, with no deaths in the treatment groups and most side effects being mild, transient, and gastrointestinal in nature, according to Akero.The company said it is advancing its evaluation of efruxifermin in an ongoing phase 3 trial.The company's shares soared past 115% in recent Monday premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4505","BK4139","AKRO","BK4585","BK4588"],"gpt_icon":0},{"id":"2506379586","title":"Akero soars as drug shows it reverses scarring in liver disease patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2506379586","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506379586?lang=en_us&edition=fundamental","pubTime":"2025-01-27 20:25","pubTimestamp":1737980750,"startTime":"0","endTime":"0","summary":"UPDATE 3-Akero soars as drug shows it reverses scarring in liver disease patientsUpdates share move in paragraphs 1 and 8, adds analyst comment in paragraph 7By Sriparna  Roy","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250127:nL3N3ON0PJ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0203202063.USD","LU2237443465.HKD","LU1093756325.SGD","LU2023250504.SGD","LU2361045086.USD","LU1868836757.USD","LU2063271972.USD","LU0256863902.USD","IE00B1BXHZ80.USD","LU2265009873.SGD","LU0006306889.USD","SG9999015986.USD","LU1267930730.SGD","LU0943347566.SGD","LU2112291526.USD","LU1061106388.HKD","LU1551013425.SGD","LLY","LU2237443382.USD","LU2211815571.USD","LU0122379950.USD","LU0320765059.SGD","IE0004445239.USD","LU1988902786.USD","LU2468319806.SGD","LU0471298694.HKD","LU0238689110.USD","LU2324357040.USD","LU1720051017.SGD","LU1868837300.USD","LU0289739699.SGD","SG9999001176.USD","LU0256863811.USD","SG9999018857.SGD","LU1917777945.USD","LU0820561909.HKD","LU2264538146.SGD","LU2237443895.HKD","IE00BFTCPJ56.SGD","BK4581","LU2237443549.SGD","LU1804176565.USD","LU0094547139.USD","IE00BJJMRZ35.SGD","LU1280957306.USD","BK4534","AKRO","LU1057294990.SGD","LU0354030438.USD","LU1974910355.USD"],"gpt_icon":1},{"id":"2506376578","title":"Akero Therapeutics Shares Double After Positive Study Results for Efruxifermin","url":"https://stock-news.laohu8.com/highlight/detail?id=2506376578","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506376578?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:59","pubTimestamp":1737979140,"startTime":"0","endTime":"0","summary":"Akero Therapeutics shares doubled to $55.64 in premarket trading after the company said it saw positive preliminary topline results from its Phase 2b study evaluating the efficacy and safety of its lead product candidate, efruxifermin.The company said that efruxifermin is for use in patients with biopsy-confirmed compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis.Among patients with baseline and week 96 biopsies, 39% of patients treated with 50 milligrams experienced reversal of cirrhosis with no worsening of MASH, compared to 15% for placebo.In a subgroup of patients with baseline and week 96 biopsies who were not taking GLP-1 at baseline, 45% in the 50 milligram efruxifermin group experienced reversal of cirrhosis with no worsening of MASH, compared to 17% for placebo, suggesting that the observed reversal of cirrhosis was not attributable to GLP-1 therapy.Efruxifermin was reported to be generally well-tolerated. There were no deaths on efruxifermin, but on","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Akero Therapeutics Shares Double After Positive Study Results for Efruxifermin","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","AKRO","BK4505","BK4139","BK4588"],"gpt_icon":0},{"id":"2506665375","title":"Akero shares double after preliminary results from mid-stage trial for liver disease drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2506665375","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506665375?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:48","pubTimestamp":1737978539,"startTime":"0","endTime":"0","summary":"Akero shares double after preliminary results from mid-stage trial for liver disease drugJan 27  - Akero Therapeutics AKRO.O shares gained 106% before the bell on Monday after the company reported results from a mid-stage trial studying its lead drug in patients with a type of liver disease.The experimental drug efruxifermin is being studied in patients with scarring due to a type of fatty liver disease known as metabolic dysfunction-associated steatohepatitis.  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