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Alnylam Pharmaceuticals

319.52

-10.8200-3.28%

Post-market: 319.520.00000.00%19:58 EDT

Volume:1.31M

Turnover:414.93M

Market Cap:42.21B

PE:137.13

High:322.35

Open:319.48

Low:313.54

Close:330.34

52wk High:495.55

52wk Low:205.87

Shares:132.11M

Float Shares:126.15M

Volume Ratio:1.21

T/O Rate:1.03%

Dividend:- -

Dividend Rate:- -

EPS(TTM):2.33

EPS(LYR):2.33

ROE:73.28%

ROA:6.81%

PB:53.49

PE(LYR):137.13

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Overview Company News Filings

Alnylam Pharmaceuticals to Unveil Five-Year Strategy at J.P. Morgan Healthcare Conference

It’s Earnings Warning Season. How to Profit From Others’ Misery

BUZZ - Nasdaq top and bottom performing stocks at about 11:01 a.m. EST on 2025-12-31

BUZZ - Nasdaq top and bottom performing stocks at about 02:45 p.m. EST on 2025-12-23

Peptidream And Alnylam Announce Achievement Of Key Milestone In Sirna Conjugate Discovery Collaboration

PeptiDream Achieves Preclinical Milestone in siRNA Delivery Collaboration with Alnylam

From on-device AI to the 'girlfriend index,' trading ideas from the research firm that nailed 2025's investment themes

BRIEF-Alnylam To Invest $250 Million To Add Enzymatic Ligation Platform

Alnylam Invests $250 Million to Expand RNAi Drug Manufacturing in Massachusetts

Alnylam Pharmaceuticals Inc - New Capabilities Operational by Late 2027

THOMSON REUTERS

Alnylam to Invest $250 Million to Add Enzymatic Ligation Platform to U.S. Manufacturing Facility to Meet Growing Global Demand for Rnai Therapeutics

THOMSON REUTERS

BRIEF-Alnylam Announces Health Canada Approval Of Amvuttra®

Alnylam Announces Health Canada Approval of Amvuttra® (Vutrisiran), the First and Only Rnai Therapeutic for the Treatment of Cardiomyopathy in Adult Patients With Attr Amyloidosis

THOMSON REUTERS

Is Alnylam (ALNY) Using Nasdaq 100 Inclusion To Quietly Redefine Its Capital Allocation Playbook?

Simply Wall St.

Alnylam Pharmaceuticals Is Maintained at Market Perform by Leerink Partners

Alnylam Pharmaceuticals Inc : Leerink Partners Cuts Target Price to $351 From $370

THOMSON REUTERS

Walmart was too late for a Nasdaq-100 spot - but these 6 stocks made the cut

Nasdaq Says Biogen, CDW Corporation, Globalfoundries, Lululemon Athletica, On Semiconductor, Trade Desk Will Be Removed From Nasdaq 100 Index

Seagate, Western Digital And Other Four Companies Will Be Added To Nasdaq 100 Index, While Lululemon, ON Semi, Trade Desk And Other Three Companies Will Be Removed

THOMSON REUTERS

Nasdaq Inc: Alnylam Pharmaceuticals, Ferrovial, Insmed, Monolithic Power Systems, Seagate Technology, Western Digital Will Be Added to Nasdaq 100 Index

THOMSON REUTERS

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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Alnylam","url":"https://stock-news.laohu8.com/highlight/detail?id=2592190845","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592190845?lang=en_us&edition=fundamental","pubTime":"2025-12-18 20:00","pubTimestamp":1766059255,"startTime":"0","endTime":"0","summary":"PeptiDream Inc. announced the achievement of a preclinical development milestone in its collaboration with Alnylam Pharmaceuticals, Inc. Under the terms of the agreement, PeptiDream will receive an undisclosed milestone payment from Alnylam and remains eligible for additional development, regulatory, and commercial milestone payments, as well as low-to-mid single-digit royalties on sales of any resulting Alnylam products. The collaboration, initiated in 2021, focuses on developing peptide-siRNA conjugates for targeted RNAi therapeutics delivery to tissues beyond the liver.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. PeptiDream Inc. published the original content used to generate this news brief via Business Wire  on December 18, 202","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251218:nNDLz4cx3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0114720955.EUR","LU0889565916.HKD","BK4139","LU0882574055.USD","BK4548","BK4588","LU0109394709.USD","ALNY","LU0320765992.SGD","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2592594908","title":"From on-device AI to the 'girlfriend index,' trading ideas from the research firm that nailed 2025's investment themes","url":"https://stock-news.laohu8.com/highlight/detail?id=2592594908","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592594908?lang=en_us&edition=fundamental","pubTime":"2025-12-18 19:52","pubTimestamp":1766058720,"startTime":"0","endTime":"0","summary":"Citrini Research urges investors to stay open-minded in the year ahead. Citrini Research says companies aren't getting enough credit by investors for shaving jobs.Be open to \"maybe,\" says a research firm whose founder who nailed diet drugs and AI themes early.\"While there's a laundry list of things I wish I had done differently since the market bottomed in October 2022, I know that the only reason I've more than tripled my money since then is because I was open to maybe,\" says Citrini Research in its just-released trades for 2026. \"Maybe the hyperscalers will actually be fine if rates are higher for longer. Maybe AI isn't the next fad investors immediately get burned on.\". Here are some of Citrini's 26 ideas for 2026, starting with a basket of companies overlooked in the rush to invest in big AI players.\"If 2026 is the year we see AI-driven head count reductions and productivity gains, one might expect that there would be some degree of anticipation of this AI-shift in the share price ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QCOM","HPQ","LU0348723411.USD","ADI","LULU","LU0385154629.USD","BK4534","CNC","TSLA","KTOS","AI","ONDS","AVY","OSCR","NXST","BK4598","MU","AS","MOH","OMC","IE00B775H168.HKD","AAPL","LU1506573853.SGD","LU0231203729.USD","LU0256863811.USD","MACW.SI","SG9999002224.SGD","LU1301847155.USD","RL","BAH","DELL","CTSH","ALNY","LU0096364046.USD","TSYW.SI","TGNA","WPP","GIB","LU2083900584.USD","LU0234570918.USD","CRSR","IBM","ARWR","LU0203201768.USD","BP","SG9999018865.SGD","WVE","BK4533","SBGI","LLY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2592990467","title":"BRIEF-Alnylam To Invest $250 Million To Add Enzymatic Ligation Platform","url":"https://stock-news.laohu8.com/highlight/detail?id=2592990467","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592990467?lang=en_us&edition=fundamental","pubTime":"2025-12-17 21:08","pubTimestamp":1765976896,"startTime":"0","endTime":"0","summary":"BRIEF-Alnylam To Invest $250 Million To Add Enzymatic Ligation Platform Dec 17 (Reuters) - Alnylam Pharmaceuticals Inc ALNY.O:ALNYLAM TO INVEST $250 MILLION TO ADD ENZYMATIC LIGATION PLATFORM TO U.S. ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251217:nTUA9XHXBG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ALNY","LU0889565916.HKD","BK4588","BK4548","LU0882574055.USD","LU0114720955.EUR","BK4585","LU0320765992.SGD","LU0109394709.USD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2592990937","title":"Alnylam Invests $250 Million to Expand RNAi Drug Manufacturing in Massachusetts","url":"https://stock-news.laohu8.com/highlight/detail?id=2592990937","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592990937?lang=en_us&edition=fundamental","pubTime":"2025-12-17 21:00","pubTimestamp":1765976447,"startTime":"0","endTime":"0","summary":"Alnylam Pharmaceuticals Inc. has announced a $250 million investment to expand its manufacturing facility in Norton, Massachusetts. The expansion will add the industry's first fully dedicated, proprietary siRNA enzymatic-ligation manufacturing platform, significantly increasing production capacity and reducing costs. The 200,000 square foot facility, which opened in 2021, will support both clinical and commercial supply of siRNA oligonucleotide drug substances, accelerating Alnylam's growing pipeline of RNAi therapeutics. The new capabilities are expected to be fully operational by late 2027, further strengthening Massachusetts' position as a global leader in life sciences and creating high-quality jobs in the region.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial,","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251217:nNDLbsqFN8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","ALNY","BK4139","LU0109394709.USD","BK4588","BK4585","LU0882574055.USD","LU0114720955.EUR","LU0889565916.HKD","LU0320765992.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2592998990","title":"Alnylam Pharmaceuticals Inc - New Capabilities Operational by Late 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2592998990","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592998990?lang=en_us&edition=fundamental","pubTime":"2025-12-17 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Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2592990626","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592990626?lang=en_us&edition=fundamental","pubTime":"2025-12-17 21:00","pubTimestamp":1765976401,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251217:nTUA9XHXBG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0109394709.USD","LU0889565916.HKD","BK4139","LU0114720955.EUR","BK4548","BK4588","BK4585","ALNY","LU0320765992.SGD","LU0882574055.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591938696","title":"BRIEF-Alnylam Announces Health Canada Approval Of Amvuttra®","url":"https://stock-news.laohu8.com/highlight/detail?id=2591938696","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591938696?lang=en_us&edition=fundamental","pubTime":"2025-12-16 22:37","pubTimestamp":1765895845,"startTime":"0","endTime":"0","summary":"BRIEF-Alnylam Announces Health Canada Approval Of Amvuttra Dec 16 (Reuters) - Alnylam Pharmaceuticals Inc ALNY.O:ALNYLAM ANNOUNCES HEALTH CANADA APPROVAL OF AMVUTTRA (VUTRISIRAN), THE FIRST AND ONLY R","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251216:nFWN3XM09T:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ALNY","LU0889565916.HKD","LU0882574055.USD","BK4139","LU0109394709.USD","BK4585","LU0114720955.EUR","BK4548","LU0320765992.SGD","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591771984","title":"Alnylam Announces Health Canada Approval of Amvuttra® (Vutrisiran), the First and Only Rnai Therapeutic for the Treatment of Cardiomyopathy in Adult Patients With Attr Amyloidosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2591771984","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591771984?lang=en_us&edition=fundamental","pubTime":"2025-12-16 21:01","pubTimestamp":1765890099,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251216:nFWN3XM09T:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4588","BK4585","LU0889565916.HKD","LU0114720955.EUR","LU0109394709.USD","BK4548","ALNY","LU0882574055.USD","LU0320765992.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591988623","title":"Is Alnylam (ALNY) Using Nasdaq 100 Inclusion To Quietly Redefine Its Capital Allocation Playbook?","url":"https://stock-news.laohu8.com/highlight/detail?id=2591988623","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591988623?lang=en_us&edition=fundamental","pubTime":"2025-12-16 13:13","pubTimestamp":1765862029,"startTime":"0","endTime":"0","summary":"Alnylam Pharmaceuticals recently reshaped its governance and capital structure, with two long-serving directors stepping down, a new independent director appointed, and a partial repurchase of US$34.4 million of its 1.00% convertible senior notes due 2027 at a total cost of US$51.9 million.\nThe company’s upcoming inclusion in the Nasdaq 100 Index on December 22, alongside evolving board expertise and debt reduction, could broaden its investor base and refine its long-term growth profile in...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-alny/alnylam-pharmaceuticals/news/is-alnylam-alny-using-nasdaq-100-inclusion-to-quietly-redefi","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-alny/alnylam-pharmaceuticals/news/is-alnylam-alny-using-nasdaq-100-inclusion-to-quietly-redefi","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LU0882574055.USD","ALNY","LU0109394709.USD","LU0889565916.HKD","BK4585","BK4588","BK4139","LU0320765992.SGD","LU0114720955.EUR","BK4548"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591181621","title":"Alnylam Pharmaceuticals Is Maintained at Market Perform by Leerink Partners","url":"https://stock-news.laohu8.com/highlight/detail?id=2591181621","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591181621?lang=en_us&edition=fundamental","pubTime":"2025-12-16 04:52","pubTimestamp":1765831920,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ALNY/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 15, 2025 15:52 ET (20:52 GMT)","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LU0109394709.USD","BK4548","LU0889565916.HKD","BK4588","LU0114720955.EUR","LU0882574055.USD","LU0320765992.SGD","ALNY","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591164307","title":"Alnylam Pharmaceuticals Inc : Leerink Partners Cuts Target Price to $351 From $370","url":"https://stock-news.laohu8.com/highlight/detail?id=2591164307","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591164307?lang=en_us&edition=fundamental","pubTime":"2025-12-15 19:57","pubTimestamp":1765799864,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251215:nFWN3XL0F0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4548","BK4139","LU0320765992.SGD","LU0882574055.USD","LU0889565916.HKD","LU0114720955.EUR","BK4588","ALNY","LU0109394709.USD","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2591658865","title":"Walmart was too late for a Nasdaq-100 spot - but these 6 stocks made the cut","url":"https://stock-news.laohu8.com/highlight/detail?id=2591658865","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591658865?lang=en_us&edition=fundamental","pubTime":"2025-12-14 00:04","pubTimestamp":1765641840,"startTime":"0","endTime":"0","summary":"Strategy maintained its place in the tech-heavy index, but Lululemon and Trade Desk are among the companies getting the boot. Walmart transferred to the Nasdaq too late to be eligible for the Nasdaq-100's annual reconstitution.Six companies will join the Nasdaq-100 later this month - but not Walmart, which switched its listing away from the New York Stock Exchange too late to qualify for a spot in the tech-heavy index.While some thought Strategy  might lose its spot due to a potentially more stringent look at whether the cryptocurrency holding company and software provider should actually be considered a nonfinancial company, it kept its place.Alnylam, which uses RNA in biotechnology, was the largest eligible candidate for a spot, according to a MarketWatch review of Nasdaq-listed companies as of Nov. 28; its market cap was about $60 billion then. Real-estate investment trusts like Equinix  aren't eligible for entry, even though the data-center provided has a larger valuation.There are","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GFS","NQmain","LU0823414551.USD","NVDS","NVDY","TTD","NVD","IE0004445015.USD","STRK","NVD2.UK","LU1244550494.USD","BK4571","NVDX","2NVD.UK","NVDU","MPWR","WMT","LU2213496289.HKD","SG9999014906.USD","USJW.SI","ALNY","NVD3.UK","BIIB","INSM","LU0957808578.USD","MACW.SI","LU1228905037.USD","FER","BK4503","LU0068578508.USD","EQIX","LU0053666078.USD","NVIW.SI","CDW","3NVD.UK","NVDS.UK","SNVD.UK","ON","NVDD"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2591800456","title":"Nasdaq Says Biogen, CDW Corporation, Globalfoundries, Lululemon Athletica, On Semiconductor, Trade Desk Will Be Removed From Nasdaq 100 Index","url":"https://stock-news.laohu8.com/highlight/detail?id=2591800456","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591800456?lang=en_us&edition=fundamental","pubTime":"2025-12-13 09:20","pubTimestamp":1765588842,"startTime":"0","endTime":"0","summary":"Dec 12 (Reuters) - Nasdaq Inc ::*NASDAQ INC - ANNOUNCES RECONSTITUTION OF NASDAQ-100 INDEX EFFECTIVE DEC 22*NASDAQ INC: SIX COMPANIES WILL BE ADDED TO NASDAQ 100 INDEX*NASDAQ INC:  BIOGEN, CDW 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