US StockDetailed Quotes

Provided by Tiger Fintech (Singapore) Pte. Ltd.

Apellis Pharmaceuticals Inc.

21.47

+0.74003.57%

Pre-market: 21.28-0.1900-0.88%04:24 EST

Volume:6.49M

Turnover:133.98M

Market Cap:2.72B

PE:59.95

High:21.80

Open:21.00

Low:19.25

Close:20.73

52wk High:35.72

52wk Low:16.10

Shares:126.53M

Float Shares:78.12M

Volume Ratio:1.67

T/O Rate:8.31%

Dividend:- -

Dividend Rate:- -

EPS(TTM):0.3581

EPS(LYR):-1.5970

ROE:14.10%

ROA:5.13%

PB:6.77

PE(LYR):-13.44

Loading ...

Overview Company News Filings

Major Issues Report

Current report, items 1.01, 2.03, 3.02, 8.01, and 9.01

Major Issues Report

Current report, items 8.01 and 9.01

Major Issues Report

Current report, items 7.01 and 9.01

Quarterly Report

Quarterly report [Sections 13 or 15(d)]

Major Issues Report

Current report, item 5.07

Major Issues Report

Current report, item 1.01

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Quarterly Report

Quarterly report [Sections 13 or 15(d)]

Major Issues Report

Current report, items 4.01 and 9.01

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Major Issues Report

Current report, items 1.01, 8.01, and 9.01

Major Issues Report

Current report, item 8.01

Major Issues Report

Current report, item 1.01

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/stock/APLS/filings?page=15"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"APLS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"APLS\",,,,,undefined,":{"symbol":"APLS","market":"US","secType":"STK","nameCN":"Apellis Pharmaceuticals Inc.","latestPrice":21.47,"timestamp":1761940800000,"preClose":20.73,"halted":0,"volume":6490131,"hourTrading":{"tag":"盘前","latestPrice":21.28,"preClose":21.47,"latestTime":"04:24 EST","volume":9,"amount":191.52,"timestamp":1762161860525},"delay":0,"floatShares":78119932,"shares":126525218,"eps":0.35814,"marketStatus":"Pre-Mkt","change":0.74,"latestTime":"11-03 04:37:12 EST","open":21,"high":21.7999,"low":19.25,"amount":133977656.37099,"amplitude":0.123005,"askPrice":23.2,"askSize":15,"bidPrice":21.27,"bidSize":100,"shortable":3,"etf":0,"ttmEps":0.35814,"tradingStatus":1,"nextMarketStatus":{"tag":"Open","tradingStatus":2,"beginTime":1762180200000},"marketStatusCode":1,"adr":0,"adrRate":0,"listingDate":1510203600000,"exchange":"NASDAQ","adjPreClose":21.47,"preHourTrading":{"tag":"盘前","latestPrice":21.28,"preClose":21.47,"latestTime":"04:24 EST","volume":9,"amount":191.52,"timestamp":1762161860525},"postHourTrading":{"tag":"盘后","latestPrice":21.77,"preClose":21.47,"latestTime":"19:57 EDT","volume":35191,"amount":755717.8135,"timestamp":1761955057233},"volumeRatio":1.6725035081607806,"impliedVol":0.6099,"impliedVolPercentile":0.4659},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"APLS\",,,,,undefined,":{"symbol":"APLS","floatShares":78119932,"roa":"5.13%","roe":"14.10%","lyrEps":-1.597013,"volumeRatio":1.6725035081607806,"shares":126525218,"dividePrice":0,"high":21.7999,"amplitude":0.123005,"preClose":20.73,"low":19.25,"week52Low":16.1,"pbRate":"6.77","psRate":"2.67","week52High":35.72,"institutionHeld":0,"latestPrice":21.47,"committee":0.73913,"eps":0.35814,"divideRate":0,"volume":6490131,"delay":0,"ttmEps":0.35814,"open":21,"prevYearClose":31.91,"prevWeekClose":21.47,"prevMonthClose":21.47,"prevQuarterClose":22.63,"fiveDayClose":28.17,"twentyDayClose":23.8,"sixtyDayClose":24.33},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/APLS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2025-10-30","symbol":"APLS","fiscalQuarterEnding":"2025/09","expectedEps":1.03,"name":null,"time":"Pre-Market","type":"earning","dateTimestamp":1761796800000,"reportTimeType":"pre","actualEps":1.67},{"market":"US","date":"2025-07-31","symbol":"APLS","fiscalQuarterEnding":"2025/06","expectedEps":-0.44,"name":null,"time":"Pre-Market","type":"earning","dateTimestamp":1753934400000,"reportTimeType":"pre","actualEps":-0.33},{"market":"US","date":"2025-05-07","symbol":"APLS","fiscalQuarterEnding":"2025/03","expectedEps":-0.36,"name":null,"time":"Pre-Market","type":"earning","dateTimestamp":1746590400000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2025-02-28","symbol":"APLS","fiscalQuarterEnding":"2024/12","expectedEps":-0.39,"name":null,"time":"Pre-Market","type":"earning","dateTimestamp":1740718800000,"reportTimeType":"pre","actualEps":-0.29},{"market":"US","date":"2024-11-05","symbol":"APLS","fiscalQuarterEnding":"2024/09","expectedEps":-0.32,"name":null,"time":"Pre-Market","type":"earning","dateTimestamp":1730782800000,"reportTimeType":"pre","actualEps":-0.46}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"APLS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"APLS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2381,"buy":0.4286,"hold":0.2857,"sell":0.0476,"strongSell":0,"meanLabel":"BUY","meanPercent":0.4286,"analysts":21,"updateTime":1760932800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/APLS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"APLS","date":"2025-10-31","current":-11.767504,"percent":0.999179,"low":-17.616885,"twenty":-13.888954,"median":-10.608763,"eighty":-7.509671,"high":84.359841,"avg":-10.534836,"sd":4.574701,"marketCap":2622867769},"quantilePoints":[{"date":"2020-11-06","current":-5.084835,"twenty":-14.810303,"median":-9.273933,"eighty":-7.440752,"marketCap":2727286633},{"date":"2020-11-13","current":-5.468915,"twenty":-14.540565,"median":-9.267652,"eighty":-7.42342,"marketCap":2933291066},{"date":"2020-11-20","current":-6.414997,"twenty":-14.368473,"median":-9.261631,"eighty":-7.362025,"marketCap":3440728457},{"date":"2020-11-27","current":-6.667756,"twenty":-14.251773,"median":-9.257734,"eighty":-7.30977,"marketCap":3576297551},{"date":"2020-12-04","current":-7.054661,"twenty":-14.234727,"median":-9.254225,"eighty":-7.255927,"marketCap":3783816723},{"date":"2020-12-11","current":-6.758128,"twenty":-14.222926,"median":-9.205001,"eighty":-7.231864,"marketCap":3624769182},{"date":"2020-12-18","current":-7.459923,"twenty":-14.211781,"median":-9.185164,"eighty":-7.236355,"marketCap":4001181694},{"date":"2020-12-24","current":-7.828471,"twenty":-14.1849,"median":-9.165621,"eighty":-7.244457,"marketCap":4198855066},{"date":"2020-12-31","current":-8.076994,"twenty":-14.108849,"median":-9.149002,"eighty":-7.252425,"marketCap":4332152052},{"date":"2021-01-08","current":-8.103823,"twenty":-13.921998,"median":-9.121037,"eighty":-7.261181,"marketCap":4346542068},{"date":"2021-01-15","current":-7.399204,"twenty":-13.899052,"median":-9.096403,"eighty":-7.268443,"marketCap":3968614817},{"date":"2021-01-22","current":-6.450298,"twenty":-13.870205,"median":-9.062099,"eighty":-7.250433,"marketCap":3459662688},{"date":"2021-01-29","current":-6.573664,"twenty":-13.862993,"median":-9.019588,"eighty":-7.220916,"marketCap":3525830716},{"date":"2021-02-05","current":-6.85728,"twenty":-13.802676,"median":-8.994976,"eighty":-7.153759,"marketCap":3677950360},{"date":"2021-02-12","current":-6.927071,"twenty":-13.766618,"median":-8.940266,"eighty":-7.132063,"marketCap":3715382943},{"date":"2021-02-19","current":-6.79046,"twenty":-13.735804,"median":-8.885933,"eighty":-7.094579,"marketCap":3642110653},{"date":"2021-02-26","current":-11.226365,"twenty":-13.679421,"median":-8.881936,"eighty":-7.086964,"marketCap":3871681332},{"date":"2021-03-05","current":-11.375521,"twenty":-13.647296,"median":-8.940266,"eighty":-7.088753,"marketCap":3923121565},{"date":"2021-03-12","current":-10.874448,"twenty":-13.621727,"median":-8.994976,"eighty":-7.094579,"marketCap":3750314530},{"date":"2021-03-19","current":-10.242863,"twenty":-13.595502,"median":-9.019588,"eighty":-7.097967,"marketCap":3532497291},{"date":"2021-03-26","current":-9.669543,"twenty":-13.577996,"median":-9.062099,"eighty":-7.113465,"marketCap":3334773893},{"date":"2021-04-01","current":-10.091376,"twenty":-13.567831,"median":-9.096403,"eighty":-7.12793,"marketCap":3480253304},{"date":"2021-04-09","current":-9.685857,"twenty":-13.552719,"median":-9.121037,"eighty":-7.140328,"marketCap":3340400169},{"date":"2021-04-16","current":-10.620416,"twenty":-13.51355,"median":-9.149002,"eighty":-7.151693,"marketCap":3662705383},{"date":"2021-04-23","current":-10.31174,"twenty":-13.461994,"median":-9.168387,"eighty":-7.154792,"marketCap":3556251073},{"date":"2021-04-30","current":-11.339023,"twenty":-13.440714,"median":-9.188325,"eighty":-7.158925,"marketCap":4078771386},{"date":"2021-05-07","current":-10.533409,"twenty":-13.382783,"median":-9.225561,"eighty":-7.177522,"marketCap":3788983010},{"date":"2021-05-14","current":-9.904582,"twenty":-13.288018,"median":-9.257174,"eighty":-7.208518,"marketCap":3562787084},{"date":"2021-05-21","current":-10.703483,"twenty":-13.260482,"median":-9.259377,"eighty":-7.228903,"marketCap":3850160556},{"date":"2021-05-28","current":-12.594439,"twenty":-13.235569,"median":-9.262664,"eighty":-7.231864,"marketCap":4530358271},{"date":"2021-06-04","current":-12.784654,"twenty":-13.231635,"median":-9.272412,"eighty":-7.234318,"marketCap":4598780527},{"date":"2021-06-11","current":-13.901325,"twenty":-13.236224,"median":-9.277226,"eighty":-7.244457,"marketCap":5000459414},{"date":"2021-06-18","current":-13.451523,"twenty":-13.377228,"median":-9.293481,"eighty":-7.254176,"marketCap":4838660904},{"date":"2021-06-25","current":-14.098253,"twenty":-13.471249,"median":-9.302777,"eighty":-7.262633,"marketCap":5071296573},{"date":"2021-07-02","current":-15.62892,"twenty":-13.572206,"median":-9.326736,"eighty":-7.270793,"marketCap":5621894486},{"date":"2021-07-09","current":-14.99338,"twenty":-13.630549,"median":-9.332047,"eighty":-7.280193,"marketCap":5393283657},{"date":"2021-07-16","current":-13.881184,"twenty":-13.761373,"median":-9.354751,"eighty":-7.289106,"marketCap":4993214705},{"date":"2021-07-23","current":-15.241778,"twenty":-13.862993,"median":-9.366739,"eighty":-7.293842,"marketCap":5482635072},{"date":"2021-07-30","current":-15.385769,"twenty":-13.921998,"median":-9.400861,"eighty":-7.329479,"marketCap":5534430342},{"date":"2021-08-06","current":-15.2391,"twenty":-14.108849,"median":-9.431166,"eighty":-7.340765,"marketCap":5481672059},{"date":"2021-08-13","current":-10.861116,"twenty":-14.098253,"median":-9.448512,"eighty":-7.341309,"marketCap":4999208756},{"date":"2021-08-20","current":-11.577504,"twenty":-14.015453,"median":-9.464251,"eighty":-7.345931,"marketCap":5328951206},{"date":"2021-08-27","current":-12.549069,"twenty":-14.00874,"median":-9.481603,"eighty":-7.349782,"marketCap":5776148091},{"date":"2021-09-03","current":-12.10298,"twenty":-13.921998,"median":-9.497473,"eighty":-7.356263,"marketCap":5570820338},{"date":"2021-09-10","current":-6.602485,"twenty":-13.90546,"median":-9.508733,"eighty":-7.354967,"marketCap":3039024745},{"date":"2021-09-17","current":-6.46639,"twenty":-13.899507,"median":-9.483211,"eighty":-7.338508,"marketCap":2976382379},{"date":"2021-09-24","current":-5.935243,"twenty":-13.884758,"median":-9.471173,"eighty":-7.277843,"marketCap":2731903149},{"date":"2021-10-01","current":-6.349197,"twenty":-13.866631,"median":-9.455946,"eighty":-7.240428,"marketCap":2922440343},{"date":"2021-10-08","current":-6.273589,"twenty":-13.862993,"median":-9.432889,"eighty":-7.189921,"marketCap":2887639029},{"date":"2021-10-15","current":-6.545779,"twenty":-13.805936,"median":-9.416298,"eighty":-7.146527,"marketCap":3012923759},{"date":"2021-10-22","current":-5.929572,"twenty":-13.788412,"median":-9.381302,"eighty":-7.096273,"marketCap":2729293050},{"date":"2021-10-29","current":-5.810489,"twenty":-13.766618,"median":-9.361783,"eighty":-7.061534,"marketCap":2674480980},{"date":"2021-11-05","current":-6.455049,"twenty":-13.727281,"median":-9.346915,"eighty":-7.035477,"marketCap":2971162182},{"date":"2021-11-12","current":-7.300403,"twenty":-13.666308,"median":-9.32819,"eighty":-7.023579,"marketCap":3797348638},{"date":"2021-11-19","current":-8.222401,"twenty":-13.645329,"median":-9.308666,"eighty":-7.026376,"marketCap":4276931273},{"date":"2021-11-26","current":-8.149405,"twenty":-13.635674,"median":-9.296887,"eighty":-7.030712,"marketCap":4238961703},{"date":"2021-12-03","current":-7.805011,"twenty":-13.616601,"median":-9.284408,"eighty":-7.034978,"marketCap":4059823220},{"date":"2021-12-10","current":-7.838702,"twenty":-13.595502,"median":-9.273915,"eighty":-7.045275,"marketCap":4077347637},{"date":"2021-12-17","current":-8.821347,"twenty":-13.578473,"median":-9.265158,"eighty":-7.053386,"marketCap":4588476460},{"date":"2021-12-23","current":-9.201303,"twenty":-13.572047,"median":-9.261631,"eighty":-7.056975,"marketCap":4786112938},{"date":"2021-12-31","current":-8.849422,"twenty":-13.567831,"median":-9.257489,"eighty":-7.06099,"marketCap":4603080140},{"date":"2022-01-07","current":-8.244862,"twenty":-13.552719,"median":-9.248532,"eighty":-7.06192,"marketCap":4288614217},{"date":"2022-01-14","current":-7.554202,"twenty":-13.51355,"median":-9.201719,"eighty":-7.071637,"marketCap":3929363673},{"date":"2022-01-21","current":-6.637067,"twenty":-13.471249,"median":-9.188325,"eighty":-7.061863,"marketCap":3452310105},{"date":"2022-01-28","current":-7.222911,"twenty":-13.449361,"median":-9.168387,"eighty":-7.061863,"marketCap":3757040241},{"date":"2022-02-04","current":-7.711426,"twenty":-13.440714,"median":-9.149002,"eighty":-7.06281,"marketCap":4011144285},{"date":"2022-02-11","current":-8.652893,"twenty":-13.429001,"median":-9.131914,"eighty":-7.069741,"marketCap":4500854376},{"date":"2022-02-18","current":-7.997796,"twenty":-13.377228,"median":-9.096706,"eighty":-7.086291,"marketCap":4160101827},{"date":"2022-02-25","current":-7.960362,"twenty":-13.357535,"median":-9.070103,"eighty":-7.087636,"marketCap":4140630253},{"date":"2022-03-04","current":-5.697419,"twenty":-13.295886,"median":-9.05421,"eighty":-7.061806,"marketCap":4252291169},{"date":"2022-03-11","current":-5.66992,"twenty":-13.276217,"median":-9.017947,"eighty":-7.043227,"marketCap":4231767584},{"date":"2022-03-18","current":-6.928302,"twenty":-13.23688,"median":-8.993324,"eighty":-7.025645,"marketCap":5170965887},{"date":"2022-03-25","current":-6.944667,"twenty":-13.233602,"median":-8.974827,"eighty":-7.010147,"marketCap":5183179823},{"date":"2022-04-01","current":-7.830211,"twenty":-13.223768,"median":-8.945735,"eighty":-6.982716,"marketCap":5844109161},{"date":"2022-04-08","current":-7.727669,"twenty":-13.214136,"median":-8.899958,"eighty":-7.010147,"marketCap":5767576629},{"date":"2022-04-14","current":-7.521161,"twenty":-13.213974,"median":-8.881936,"eighty":-7.012325,"marketCap":5613448614},{"date":"2022-04-22","current":-6.881846,"twenty":-13.18599,"median":-8.856399,"eighty":-7.012325,"marketCap":5136293555},{"date":"2022-04-29","current":-6.209925,"twenty":-13.160706,"median":-8.849422,"eighty":-6.976618,"marketCap":4634802206},{"date":"2022-05-06","current":-6.173022,"twenty":-13.154893,"median":-8.835665,"eighty":-6.947812,"marketCap":4331177119},{"date":"2022-05-13","current":-5.989319,"twenty":-13.138702,"median":-8.819475,"eighty":-6.935454,"marketCap":4202285720},{"date":"2022-05-20","current":-6.803077,"twenty":-13.129438,"median":-8.807379,"eighty":-6.922194,"marketCap":4773242664},{"date":"2022-05-27","current":-6.469072,"twenty":-13.127255,"median":-8.793984,"eighty":-6.881384,"marketCap":4538894664},{"date":"2022-06-03","current":-6.912387,"twenty":-13.118962,"median":-8.766558,"eighty":-6.859062,"marketCap":4849938373},{"date":"2022-06-10","current":-6.241341,"twenty":-13.107968,"median":-8.748239,"eighty":-6.850221,"marketCap":4379111937},{"date":"2022-06-17","current":-6.701357,"twenty":-13.093013,"median":-8.709044,"eighty":-6.834807,"marketCap":4701873046},{"date":"2022-06-24","current":-7.023216,"twenty":-13.085535,"median":-8.698732,"eighty":-6.830352,"marketCap":4927699300},{"date":"2022-07-01","current":-6.897205,"twenty":-13.081797,"median":-8.670291,"eighty":-6.830352,"marketCap":4839286191},{"date":"2022-07-08","current":-7.433132,"twenty":-13.064973,"median":-8.665648,"eighty":-6.834606,"marketCap":5215308209},{"date":"2022-07-15","current":-6.99437,"twenty":-13.015536,"median":-8.655027,"eighty":-6.835304,"marketCap":4907460155},{"date":"2022-07-22","current":-8.014604,"twenty":-12.993666,"median":-8.648901,"eighty":-6.835304,"marketCap":5623286772},{"date":"2022-07-29","current":-8.544458,"twenty":-12.972542,"median":-8.646506,"eighty":-6.838161,"marketCap":5995047917},{"date":"2022-08-05","current":-9.825463,"twenty":-12.941594,"median":-8.648901,"eighty":-6.845871,"marketCap":6893839840},{"date":"2022-08-12","current":-11.693547,"twenty":-12.924771,"median":-8.655027,"eighty":-6.850076,"marketCap":7465347474},{"date":"2022-08-19","current":-11.172113,"twenty":-12.917293,"median":-8.665648,"eighty":-6.850625,"marketCap":7132455600},{"date":"2022-08-26","current":-9.607811,"twenty":-12.911685,"median":-8.672321,"eighty":-6.851766,"marketCap":6133779978},{"date":"2022-09-02","current":-10.788351,"twenty":-12.878036,"median":-8.699023,"eighty":-6.85321,"marketCap":6887455970},{"date":"2022-09-09","current":-11.628153,"twenty":-12.833172,"median":-8.70712,"eighty":-6.85728,"marketCap":7423598658},{"date":"2022-09-16","current":-10.765979,"twenty":-12.810499,"median":-8.718467,"eighty":-6.86025,"marketCap":6873173480},{"date":"2022-09-23","current":-10.036316,"twenty":-12.784654,"median":-8.748609,"eighty":-6.860768,"marketCap":6407344587},{"date":"2022-09-30","current":-11.753779,"twenty":-12.764837,"median":-8.79359,"eighty":-6.865323,"marketCap":7503800331},{"date":"2022-10-07","current":-10.020828,"twenty":-12.758397,"median":-8.802621,"eighty":-6.879536,"marketCap":6397456710},{"date":"2022-10-14","current":-9.798831,"twenty":-12.728708,"median":-8.817779,"eighty":-6.881846,"marketCap":6255730466},{"date":"2022-10-21","current":-10.294451,"twenty":-12.711663,"median":-8.827761,"eighty":-6.897205,"marketCap":6572142545},{"date":"2022-10-28","current":-10.428682,"twenty":-12.711663,"median":-8.84139,"eighty":-6.899334,"marketCap":6657837483},{"date":"2022-11-04","current":-8.676801,"twenty":-12.711663,"median":-8.850358,"eighty":-6.906315,"marketCap":5539408678},{"date":"2022-11-11","current":-7.873168,"twenty":-12.627927,"median":-8.834175,"eighty":-6.909958,"marketCap":4992485947},{"date":"2022-11-18","current":-8.797371,"twenty":-12.529297,"median":-8.804641,"eighty":-6.909958,"marketCap":5578536346},{"date":"2022-11-25","current":-8.886304,"twenty":-12.467076,"median":-8.793984,"eighty":-6.909958,"marketCap":5634929875},{"date":"2022-12-02","current":-8.828759,"twenty":-12.360248,"median":-8.748853,"eighty":-6.909958,"marketCap":5598439944},{"date":"2022-12-09","current":-8.567192,"twenty":-12.23104,"median":-8.718467,"eighty":-6.909958,"marketCap":5432576624},{"date":"2022-12-16","current":-9.242035,"twenty":-12.220264,"median":-8.718467,"eighty":-6.909958,"marketCap":5860503991},{"date":"2022-12-23","current":-8.868866,"twenty":-12.092957,"median":-8.718467,"eighty":-6.909958,"marketCap":5623872320},{"date":"2022-12-30","current":-9.017088,"twenty":-12.056162,"median":-8.709044,"eighty":-6.909958,"marketCap":5717861535},{"date":"2023-01-06","current":-8.124272,"twenty":-11.95426,"median":-8.705195,"eighty":-6.909958,"marketCap":5151714734},{"date":"2023-01-13","current":-9.165309,"twenty":-11.92544,"median":-8.698732,"eighty":-6.909958,"marketCap":5811850750},{"date":"2023-01-20","current":-9.076376,"twenty":-11.814354,"median":-8.698732,"eighty":-6.909958,"marketCap":5755457221},{"date":"2023-01-27","current":-9.201928,"twenty":-11.761044,"median":-8.698732,"eighty":-6.909958,"marketCap":5835071615},{"date":"2023-02-03","current":-9.550684,"twenty":-11.698313,"median":-8.698732,"eighty":-6.909958,"marketCap":6056222709},{"date":"2023-02-10","current":-8.929899,"twenty":-11.650339,"median":-8.698732,"eighty":-6.909958,"marketCap":5662573761},{"date":"2023-02-17","current":-9.676237,"twenty":-11.586338,"median":-8.698732,"eighty":-6.909958,"marketCap":6135837103},{"date":"2023-02-24","current":-11.705027,"twenty":-11.575978,"median":-8.698732,"eighty":-6.909958,"marketCap":7633690990},{"date":"2023-03-03","current":-11.487928,"twenty":-11.5493,"median":-8.698732,"eighty":-6.909958,"marketCap":7492105302},{"date":"2023-03-10","current":-10.999983,"twenty":-11.490244,"median":-8.698732,"eighty":-6.909958,"marketCap":7173881069},{"date":"2023-03-17","current":-11.141417,"twenty":-11.472519,"median":-8.698732,"eighty":-6.909958,"marketCap":7266119977},{"date":"2023-03-24","current":-11.143185,"twenty":-11.422592,"median":-8.698732,"eighty":-6.909958,"marketCap":7267272964},{"date":"2023-03-31","current":-11.661184,"twenty":-11.426807,"median":-8.699023,"eighty":-6.911173,"marketCap":7605097964},{"date":"2023-04-06","current":-13.669539,"twenty":-11.426807,"median":-8.699023,"eighty":-6.911173,"marketCap":8914890458},{"date":"2023-04-14","current":-13.994836,"twenty":-11.422592,"median":-8.698732,"eighty":-6.909958,"marketCap":9127039946},{"date":"2023-04-21","current":-14.572945,"twenty":-11.422592,"median":-8.698732,"eighty":-6.909958,"marketCap":9504066483},{"date":"2023-04-28","current":-14.746584,"twenty":-11.422592,"median":-8.698732,"eighty":-6.909958,"marketCap":9617309291},{"date":"2023-05-05","current":-15.02983,"twenty":-11.422592,"median":-8.698732,"eighty":-6.909958,"marketCap":9802034126},{"date":"2023-05-12","current":-14.921678,"twenty":-11.409463,"median":-8.691192,"eighty":-6.908744,"marketCap":10311103488},{"date":"2023-05-19","current":-14.746407,"twenty":-11.390888,"median":-8.683652,"eighty":-6.907529,"marketCap":10189988200},{"date":"2023-05-26","current":-14.35036,"twenty":-11.390888,"median":-8.683652,"eighty":-6.907529,"marketCap":9916314231},{"date":"2023-06-02","current":-14.714386,"twenty":-11.390888,"median":-8.683652,"eighty":-6.907529,"marketCap":10167861368},{"date":"2023-06-09","current":-15.196383,"twenty":-11.390888,"median":-8.683652,"eighty":-6.907529,"marketCap":10500928411},{"date":"2023-06-16","current":-15.10032,"twenty":-11.390888,"median":-8.683652,"eighty":-6.907529,"marketCap":10434547916},{"date":"2023-06-21","current":-14.857637,"twenty":-11.385389,"median":-8.682967,"eighty":-6.906315,"marketCap":10266849825},{"date":"2023-06-30","current":-15.017741,"twenty":-11.366238,"median":-8.676801,"eighty":-6.902126,"marketCap":10377483982},{"date":"2023-07-07","current":-14.692477,"twenty":-11.366238,"median":-8.676801,"eighty":-6.902126,"marketCap":10152721957},{"date":"2023-07-14","current":-14.490241,"twenty":-11.356906,"median":-8.674561,"eighty":-6.90073,"marketCap":10012973547},{"date":"2023-07-19","current":-6.741214,"twenty":-11.325922,"median":-8.670291,"eighty":-6.897631,"marketCap":4658280320},{"date":"2023-07-28","current":-5.41151,"twenty":-11.272611,"median":-8.652095,"eighty":-6.859656,"marketCap":3739434526},{"date":"2023-08-04","current":-4.275329,"twenty":-11.252888,"median":-8.63052,"eighty":-6.84897,"marketCap":2809211715},{"date":"2023-08-11","current":-4.839758,"twenty":-11.200861,"median":-8.606774,"eighty":-6.826251,"marketCap":3180084175},{"date":"2023-08-18","current":-5.536784,"twenty":-11.148574,"median":-8.570794,"eighty":-6.80213,"marketCap":3638082230},{"date":"2023-08-25","current":-7.181692,"twenty":-11.114125,"median":-8.560417,"eighty":-6.794481,"marketCap":4718910543},{"date":"2023-09-01","current":-7.563354,"twenty":-11.062218,"median":-8.539877,"eighty":-6.794481,"marketCap":4969690968},{"date":"2023-09-08","current":-7.703118,"twenty":-11.003445,"median":-8.503462,"eighty":-6.794481,"marketCap":5061526054},{"date":"2023-09-15","current":-7.760457,"twenty":-10.966303,"median":-8.462809,"eighty":-6.794481,"marketCap":5099201986},{"date":"2023-09-22","current":-8.421645,"twenty":-10.942445,"median":-8.454045,"eighty":-6.794481,"marketCap":5533652583},{"date":"2023-09-29","current":-7.108227,"twenty":-10.855132,"median":-8.432644,"eighty":-6.793476,"marketCap":4670638254},{"date":"2023-10-06","current":-7.102851,"twenty":-10.831374,"median":-8.421645,"eighty":-6.775329,"marketCap":4667106135},{"date":"2023-10-13","current":-7.866175,"twenty":-10.834815,"median":-8.410664,"eighty":-6.771926,"marketCap":5168666987},{"date":"2023-10-20","current":-8.274714,"twenty":-10.818871,"median":-8.382225,"eighty":-6.768524,"marketCap":5437108006},{"date":"2023-10-27","current":-8.681462,"twenty":-10.82265,"median":-8.374619,"eighty":-6.762784,"marketCap":5704371652},{"date":"2023-11-03","current":-9.643569,"twenty":-10.82265,"median":-8.374619,"eighty":-6.762784,"marketCap":5844417287},{"date":"2023-11-10","current":-9.064798,"twenty":-10.82265,"median":-8.374619,"eighty":-6.762784,"marketCap":5493657450},{"date":"2023-11-17","current":-9.36396,"twenty":-10.82265,"median":-8.4065,"eighty":-6.762784,"marketCap":5674962366},{"date":"2023-11-24","current":-9.463681,"twenty":-10.82265,"median":-8.420288,"eighty":-6.762784,"marketCap":5735397338},{"date":"2023-12-01","current":-10.533233,"twenty":-10.82265,"median":-8.427015,"eighty":-6.762784,"marketCap":6383592037},{"date":"2023-12-08","current":-12.521779,"twenty":-10.847977,"median":-8.425608,"eighty":-6.761615,"marketCap":7588736477},{"date":"2023-12-14","current":-12.294963,"twenty":-10.912621,"median":-8.425608,"eighty":-6.761615,"marketCap":7451276541},{"date":"2023-12-22","current":-10.644685,"twenty":-10.944944,"median":-8.443261,"eighty":-6.760446,"marketCap":6451137005},{"date":"2023-12-29","current":-12.285187,"twenty":-10.954119,"median":-8.454884,"eighty":-6.765122,"marketCap":7445351544},{"date":"2024-01-05","current":-11.874573,"twenty":-10.978879,"median":-8.474975,"eighty":-6.763953,"marketCap":7196501659},{"date":"2024-01-12","current":-12.922617,"twenty":-11.057819,"median":-8.524217,"eighty":-6.763953,"marketCap":7831661365},{"date":"2024-01-19","current":-12.490494,"twenty":-11.090969,"median":-8.544458,"eighty":-6.762784,"marketCap":7569776486},{"date":"2024-01-26","current":-12.953902,"twenty":-11.142923,"median":-8.563011,"eighty":-6.778731,"marketCap":7850621356},{"date":"2024-02-02","current":-12.148316,"twenty":-11.179629,"median":-8.57847,"eighty":-6.788795,"marketCap":7362401582},{"date":"2024-02-09","current":-13.319544,"twenty":-11.236222,"median":-8.606774,"eighty":-6.794481,"marketCap":8072216253},{"date":"2024-02-16","current":-13.213957,"twenty":-11.274745,"median":-8.63052,"eighty":-6.794481,"marketCap":8008226283},{"date":"2024-02-23","current":-13.215913,"twenty":-11.313053,"median":-8.6487,"eighty":-6.794481,"marketCap":8009411282},{"date":"2024-03-01","current":-14.135557,"twenty":-11.369478,"median":-8.655341,"eighty":-6.805226,"marketCap":7472450985},{"date":"2024-03-08","current":-14.242765,"twenty":-11.43369,"median":-8.676801,"eighty":-6.805226,"marketCap":7529124407},{"date":"2024-03-15","current":-12.88327,"twenty":-11.482244,"median":-8.676801,"eighty":-6.805226,"marketCap":6810457183},{"date":"2024-03-22","current":-12.912923,"twenty":-11.565043,"median":-8.676801,"eighty":-6.805226,"marketCap":6826132810},{"date":"2024-03-28","current":-13.341757,"twenty":-11.577504,"median":-8.676801,"eighty":-6.805226,"marketCap":7052826499},{"date":"2024-04-05","current":-12.785185,"twenty":-11.634815,"median":-8.674561,"eighty":-6.804796,"marketCap":6758607031},{"date":"2024-04-12","current":-12.712192,"twenty":-11.661184,"median":-8.674561,"eighty":-6.804796,"marketCap":6720020871},{"date":"2024-04-19","current":-10.837184,"twenty":-11.67511,"median":-8.674561,"eighty":-6.804796,"marketCap":5728838894},{"date":"2024-04-26","current":-10.932987,"twenty":-11.672576,"median":-8.676801,"eighty":-6.805226,"marketCap":5779483229},{"date":"2024-05-03","current":-10.896587,"twenty":-11.672576,"median":-8.676801,"eighty":-6.805226,"marketCap":5760241042},{"date":"2024-05-10","current":-12.367116,"twenty":-11.705027,"median":-8.683652,"eighty":-6.805226,"marketCap":5160463398},{"date":"2024-05-17","current":-12.215871,"twenty":-11.747316,"median":-8.706695,"eighty":-6.805226,"marketCap":5097353310},{"date":"2024-05-24","current":-11.54109,"twenty":-11.772709,"median":-8.732851,"eighty":-6.805226,"marketCap":4815785222},{"date":"2024-05-31","current":-11.852304,"twenty":-11.811584,"median":-8.748853,"eighty":-6.805226,"marketCap":4945646366},{"date":"2024-06-07","current":-11.93956,"twenty":-11.813466,"median":-8.804346,"eighty":-6.805226,"marketCap":4982056032},{"date":"2024-06-14","current":-12.37875,"twenty":-11.83963,"median":-8.820411,"eighty":-6.804796,"marketCap":5165318020},{"date":"2024-06-21","current":-11.555633,"twenty":-11.860927,"median":-8.821347,"eighty":-6.804366,"marketCap":4821853500},{"date":"2024-06-28","current":-12.076261,"twenty":-11.927867,"median":-8.818627,"eighty":-6.803077,"marketCap":5039097843},{"date":"2024-07-05","current":-10.299143,"twenty":-11.927867,"median":-8.818627,"eighty":-6.803077,"marketCap":4297554302},{"date":"2024-07-12","current":-11.311315,"twenty":-11.927867,"median":-8.818627,"eighty":-6.803077,"marketCap":4719906433},{"date":"2024-07-15","current":-11.497462,"twenty":-11.927867,"median":-8.818627,"eighty":-6.803077,"marketCap":4797580389},{"date":"2024-08-02","current":-13.124818,"twenty":-11.9709,"median":-8.781677,"eighty":-6.79247,"marketCap":4369159980},{"date":"2024-08-09","current":-13.775357,"twenty":-12.073934,"median":-8.804346,"eighty":-6.79247,"marketCap":4585719912},{"date":"2024-08-16","current":-13.760726,"twenty":-12.130246,"median":-8.804346,"eighty":-6.79247,"marketCap":4580849259},{"date":"2024-08-23","current":-14.316715,"twenty":-12.215871,"median":-8.804346,"eighty":-6.79247,"marketCap":4765934077},{"date":"2024-08-30","current":-14.163086,"twenty":-12.280806,"median":-8.804346,"eighty":-6.79247,"marketCap":4714792220},{"date":"2024-09-06","current":-14.371582,"twenty":-12.309961,"median":-8.804346,"eighty":-6.79247,"marketCap":4784199027},{"date":"2024-09-13","current":-13.453469,"twenty":-12.365801,"median":-8.804346,"eighty":-6.79247,"marketCap":4478565543},{"date":"2024-09-20","current":-13.43518,"twenty":-12.426742,"median":-8.821347,"eighty":-6.79247,"marketCap":4472477227},{"date":"2024-09-27","current":-10.918598,"twenty":-12.426742,"median":-8.841103,"eighty":-6.79247,"marketCap":3634724890},{"date":"2024-10-04","current":-10.263848,"twenty":-12.426742,"median":-8.868866,"eighty":-6.79247,"marketCap":3416763163},{"date":"2024-10-11","current":-9.755411,"twenty":-12.426742,"median":-8.922924,"eighty":-6.79247,"marketCap":3247507967},{"date":"2024-10-18","current":-10.212639,"twenty":-12.426742,"median":-8.943569,"eighty":-6.79247,"marketCap":3399715877},{"date":"2024-10-25","current":-10.088273,"twenty":-12.426742,"median":-8.943569,"eighty":-6.79247,"marketCap":3358315326},{"date":"2024-10-31","current":-10.135824,"twenty":-12.426742,"median":-8.943569,"eighty":-6.79247,"marketCap":3374144948},{"date":"2024-11-08","current":-14.294446,"twenty":-12.505806,"median":-8.962122,"eighty":-6.791465,"marketCap":3575055308},{"date":"2024-11-15","current":-13.956234,"twenty":-12.563882,"median":-8.987814,"eighty":-6.791465,"marketCap":3490468057},{"date":"2024-11-22","current":-13.802049,"twenty":-12.65836,"median":-9.017088,"eighty":-6.791465,"marketCap":3451906221},{"date":"2024-11-29","current":-16.875802,"twenty":-12.710823,"median":-9.057031,"eighty":-6.791465,"marketCap":4220655066},{"date":"2024-12-06","current":-16.637064,"twenty":-12.776871,"median":-9.077248,"eighty":-6.791465,"marketCap":4160946418},{"date":"2024-12-13","current":-16.283931,"twenty":-12.840707,"median":-9.131914,"eighty":-6.797004,"marketCap":4072627376},{"date":"2024-12-20","current":-16.482879,"twenty":-12.920678,"median":-9.184491,"eighty":-6.797004,"marketCap":4122384583},{"date":"2024-12-27","current":-16.390866,"twenty":-12.951637,"median":-9.195825,"eighty":-6.797004,"marketCap":4099371875},{"date":"2025-01-03","current":-16.492827,"twenty":-12.982777,"median":-9.205416,"eighty":-6.797004,"marketCap":4124872443},{"date":"2025-01-10","current":-16.413247,"twenty":-13.006695,"median":-9.217622,"eighty":-6.795486,"marketCap":4104969561},{"date":"2025-01-17","current":-14.786844,"twenty":-13.021176,"median":-9.217622,"eighty":-6.795486,"marketCap":3698204395},{"date":"2025-01-24","current":-15.299136,"twenty":-13.021176,"median":-9.217622,"eighty":-6.795486,"marketCap":3826329202},{"date":"2025-01-31","current":-15.115109,"twenty":-13.021176,"median":-9.217622,"eighty":-6.795486,"marketCap":3780303786},{"date":"2025-02-07","current":-15.020608,"twenty":-13.021176,"median":-9.217622,"eighty":-6.795486,"marketCap":3756669113},{"date":"2025-02-14","current":-13.657811,"twenty":-13.021176,"median":-9.217622,"eighty":-6.795486,"marketCap":3415832246},{"date":"2025-02-21","current":-14.100472,"twenty":-13.032819,"median":-9.217622,"eighty":-6.795486,"marketCap":3526542031},{"date":"2025-02-28","current":-12.931649,"twenty":-13.079041,"median":-9.221223,"eighty":-6.795486,"marketCap":3234218442},{"date":"2025-03-07","current":-16.060706,"twenty":-13.157138,"median":-9.330898,"eighty":-6.794481,"marketCap":3178060385},{"date":"2025-03-14","current":-15.458112,"twenty":-13.218067,"median":-9.463681,"eighty":-6.805292,"marketCap":3058820362},{"date":"2025-03-21","current":-15.318564,"twenty":-13.321108,"median":-9.534479,"eighty":-6.836195,"marketCap":3031206883},{"date":"2025-03-28","current":-15.401025,"twenty":-13.365846,"median":-9.597416,"eighty":-6.856263,"marketCap":3047523939},{"date":"2025-04-04","current":-14.284641,"twenty":-13.406043,"median":-9.653474,"eighty":-6.876693,"marketCap":2826616108},{"date":"2025-04-11","current":-11.918668,"twenty":-13.405577,"median":-9.683526,"eighty":-6.899334,"marketCap":2358442126},{"date":"2025-04-17","current":-11.519053,"twenty":-13.405577,"median":-9.756976,"eighty":-6.899334,"marketCap":2279367164},{"date":"2025-04-25","current":-11.125781,"twenty":-13.406043,"median":-9.825054,"eighty":-6.898908,"marketCap":2201547360},{"date":"2025-05-02","current":-12.753817,"twenty":-13.406043,"median":-9.856569,"eighty":-6.898908,"marketCap":2523699780},{"date":"2025-05-09","current":-10.007158,"twenty":-13.406043,"median":-9.927613,"eighty":-6.898908,"marketCap":2238401050},{"date":"2025-05-16","current":-9.192426,"twenty":-13.406043,"median":-9.927613,"eighty":-6.898908,"marketCap":2056161773},{"date":"2025-05-23","current":-9.990301,"twenty":-13.406043,"median":-9.947126,"eighty":-6.898908,"marketCap":2234630582},{"date":"2025-05-30","current":-9.782404,"twenty":-13.406043,"median":-9.947126,"eighty":-6.898908,"marketCap":2188128146},{"date":"2025-06-06","current":-10.731988,"twenty":-13.406043,"median":-9.986635,"eighty":-6.898908,"marketCap":2400531166},{"date":"2025-06-13","current":-10.82189,"twenty":-13.406043,"median":-10.007317,"eighty":-6.898908,"marketCap":2420640327},{"date":"2025-06-20","current":-9.979064,"twenty":-13.406509,"median":-10.020828,"eighty":-6.898482,"marketCap":2232116937},{"date":"2025-06-27","current":-10.338669,"twenty":-13.406509,"median":-10.02609,"eighty":-6.898482,"marketCap":2312553584},{"date":"2025-07-03","current":-10.260006,"twenty":-13.406509,"median":-10.040721,"eighty":-6.898482,"marketCap":2294958067},{"date":"2025-07-11","current":-10.973599,"twenty":-13.406509,"median":-10.052109,"eighty":-6.898482,"marketCap":2454574537},{"date":"2025-07-18","current":-11.26016,"twenty":-13.406509,"median":-10.095588,"eighty":-6.898482,"marketCap":2518672490},{"date":"2025-07-25","current":-11.288254,"twenty":-13.406509,"median":-10.135824,"eighty":-6.898482,"marketCap":2524956603},{"date":"2025-08-01","current":-12.364759,"twenty":-13.406509,"median":-10.153337,"eighty":-6.922181,"marketCap":2821316589},{"date":"2025-08-08","current":-13.466186,"twenty":-13.430537,"median":-10.206685,"eighty":-6.953032,"marketCap":3072633510},{"date":"2025-08-15","current":-15.287138,"twenty":-13.452301,"median":-10.234585,"eighty":-6.989708,"marketCap":3488127314},{"date":"2025-08-22","current":-15.287138,"twenty":-13.545116,"median":-10.260006,"eighty":-7.043117,"marketCap":3488127314},{"date":"2025-08-29","current":-15.525134,"twenty":-13.626419,"median":-10.299143,"eighty":-7.064249,"marketCap":3542431975},{"date":"2025-09-05","current":-15.857223,"twenty":-13.653832,"median":-10.333541,"eighty":-7.105001,"marketCap":3618205921},{"date":"2025-09-12","current":-14.05841,"twenty":-13.743558,"median":-10.400477,"eighty":-7.186209,"marketCap":3207763714},{"date":"2025-09-19","current":-12.940379,"twenty":-13.756688,"median":-10.417477,"eighty":-7.251209,"marketCap":2952658095},{"date":"2025-09-26","current":-12.298342,"twenty":-13.756688,"median":-10.439007,"eighty":-7.289813,"marketCap":2806161800},{"date":"2025-10-03","current":-12.790939,"twenty":-13.756688,"median":-10.505757,"eighty":-7.31776,"marketCap":2918559820},{"date":"2025-10-10","current":-14.241059,"twenty":-13.773467,"median":-10.533322,"eighty":-7.390167,"marketCap":3249439384},{"date":"2025-10-17","current":-13.366559,"twenty":-13.792099,"median":-10.549158,"eighty":-7.435651,"marketCap":3049901326},{"date":"2025-10-24","current":-15.835083,"twenty":-13.828984,"median":-10.58028,"eighty":-7.456534,"marketCap":3613154325},{"date":"2025-10-31","current":58.304089,"twenty":-13.888954,"median":-10.608763,"eighty":-7.509671,"marketCap":2622867769}],"updateTime":1762136949216},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"APLS\",pageSize:20,pageCount:15,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"8932953","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519245912-APLS","pdf_url":null,"pub_time":1568563200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 1.01, 2.03, 3.02, 8.01, and 9.01","symbol":"APLS","title":"Current report, items 1.01, 2.03, 3.02, 8.01, and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/0001193125-19-245912-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 1.01, 2.03, 3.02, 8.01, and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-4.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/d802733dex41.htm","primary":true,"translateUrl":null,"linkName":"d802733dex41.htm","type":"EX-4.1","id":"NTFILE7fqugb6eqApKP6Fm","market":"us","size":592931},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/d802733d8k.htm","primary":false,"translateUrl":null,"linkName":"d802733d8k.htm","type":"8-K","id":"NTFILEAWT591JPYZjymHjd","market":"us","size":47316},{"description":"EX-10.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/d802733dex101.htm","primary":false,"translateUrl":null,"linkName":"d802733dex101.htm","type":"EX-10.1","id":"NTFILE7S31C13BibkBAQGE","market":"us","size":205378},{"description":"EX-99.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/d802733dex991.htm","primary":false,"translateUrl":null,"linkName":"d802733dex991.htm","type":"EX-99.1","id":"NTFILEBz5wSHVcdGkSbvRD","market":"us","size":14294},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/apls-20190911.xsd","primary":false,"translateUrl":null,"linkName":"apls-20190911.xsd","type":"EX-101.SCH","id":"NTFILE5aRgeNJjyrFAnYHA","market":"us","size":3067},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/apls-20190911_lab.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_lab.xml","type":"EX-101.LAB","id":"NTFILEFufKQLidvefYcwHQ","market":"us","size":18139},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/apls-20190911_pre.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_pre.xml","type":"EX-101.PRE","id":"NTFILEDTUj9Zz9aAxkDDzV","market":"us","size":11406},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp74.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp74.jpg","type":"GRAPHIC","id":"NTFILEC4E42kDtezqWmYxJ","market":"us","size":2783},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp75.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp75.jpg","type":"GRAPHIC","id":"NTFILE2PAJdRcc2wVNF2o1","market":"us","size":3424},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp76.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp76.jpg","type":"GRAPHIC","id":"NTFILE8uM58fW4dhk2pbWF","market":"us","size":3392},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp77.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp77.jpg","type":"GRAPHIC","id":"NTFILE3mhjhgArH9xcwhjU","market":"us","size":3766},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp79.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp79.jpg","type":"GRAPHIC","id":"NTFILEFT8HNVW7ANmbdbzR","market":"us","size":2323},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733dsp80.jpg","primary":false,"translateUrl":null,"linkName":"g802733dsp80.jpg","type":"GRAPHIC","id":"NTFILE3oc9ytAhnSgGX3rF","market":"us","size":4445},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/g802733g0916221244810.jpg","primary":false,"translateUrl":null,"linkName":"g802733g0916221244810.jpg","type":"GRAPHIC","id":"NTFILE7Ls13pSP5kECYZ8o","market":"us","size":2579},{"description":"EXTRACTED XBRL INSTANCE DOCUMENT","seq":22,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519245912/d802733d8k_htm.xml","primary":false,"translateUrl":null,"linkName":"d802733d8k_htm.xml","type":"XML","id":"NTFILEDkSGjKeFGqsDYWrQ","market":"us","size":3333}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-09-16 00:00","pubTimestamp":1568563200,"title_zh":"Current report, items 1.01, 2.03, 3.02, 8.01, and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932954","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519243453-APLS","pdf_url":null,"pub_time":1568217600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 8.01 and 9.01","symbol":"APLS","title":"Current report, items 8.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/0001193125-19-243453-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 8.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/d801818dex991.htm","primary":true,"translateUrl":null,"linkName":"d801818dex991.htm","type":"EX-99.1","id":"NTFILE82dSmygZdjFUsxD1","market":"us","size":14857},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/d801818d8k.htm","primary":false,"translateUrl":null,"linkName":"d801818d8k.htm","type":"8-K","id":"NTFILEBaJ2hLPfMy8d7R3x","market":"us","size":32502},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/apls-20190911.xsd","primary":false,"translateUrl":null,"linkName":"apls-20190911.xsd","type":"EX-101.SCH","id":"NTFILEDjibQapLMaepraAJ","market":"us","size":3066},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/apls-20190911_lab.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_lab.xml","type":"EX-101.LAB","id":"NTFILEDseqcDWUFNgHE1Fo","market":"us","size":18138},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/apls-20190911_pre.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_pre.xml","type":"EX-101.PRE","id":"NTFILEHwzU5tCE8rwT1nv7","market":"us","size":11405},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/g801818g0912093308189.jpg","primary":false,"translateUrl":null,"linkName":"g801818g0912093308189.jpg","type":"GRAPHIC","id":"NTFILED93zJ5Wu9E1TLeMh","market":"us","size":2579},{"description":"EXTRACTED XBRL INSTANCE DOCUMENT","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243453/d801818d8k_htm.xml","primary":false,"translateUrl":null,"linkName":"d801818d8k_htm.xml","type":"XML","id":"NTFILECpLcEVAsjkqUtoR2","market":"us","size":3333}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-09-12 00:00","pubTimestamp":1568217600,"title_zh":"Current report, items 8.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932969","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519243049-APLS","pdf_url":null,"pub_time":1568131200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 7.01 and 9.01","symbol":"APLS","title":"Current report, items 7.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/0001193125-19-243049-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 7.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/d643067dex991.htm","primary":true,"translateUrl":null,"linkName":"d643067dex991.htm","type":"EX-99.1","id":"NTFILE4PKodDzKuTUdpoNS","market":"us","size":12409},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/d643067d8k.htm","primary":false,"translateUrl":null,"linkName":"d643067d8k.htm","type":"8-K","id":"NTFILEHe5bQRYR1MpWwWv4","market":"us","size":32505},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/apls-20190911.xsd","primary":false,"translateUrl":null,"linkName":"apls-20190911.xsd","type":"EX-101.SCH","id":"NTFILE5AmRMVqTzow4BQg5","market":"us","size":3067},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/apls-20190911_lab.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_lab.xml","type":"EX-101.LAB","id":"NTFILEH8aQtjfD5Qjdbyrx","market":"us","size":18139},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/apls-20190911_pre.xml","primary":false,"translateUrl":null,"linkName":"apls-20190911_pre.xml","type":"EX-101.PRE","id":"NTFILEGAhZz5Xstsypzw95","market":"us","size":11406},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/g643067g64t64.jpg","primary":false,"translateUrl":null,"linkName":"g643067g64t64.jpg","type":"GRAPHIC","id":"NTFILEunrWxwtEVYGZHHTy","market":"us","size":7606},{"description":"EXTRACTED XBRL INSTANCE DOCUMENT","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519243049/d643067d8k_htm.xml","primary":false,"translateUrl":null,"linkName":"d643067d8k_htm.xml","type":"XML","id":"NTFILEHFG51NpE3LghNVLN","market":"us","size":3333}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-09-11 00:00","pubTimestamp":1568131200,"title_zh":"Current report, items 7.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932984","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019027462-APLS","pdf_url":null,"pub_time":1564502400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"APLS","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/0001564590-19-027462-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-10q_20190630.htm","primary":true,"translateUrl":null,"linkName":"apls-10q_20190630.htm","type":"10-Q","id":"NTFILED1zJ5tn9JqM9YK6Y","market":"us","size":1948600},{"description":"EXHIBIT 10.1.DOCX","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex101_11.htm","primary":false,"translateUrl":null,"linkName":"apls-ex101_11.htm","type":"EX-10.1","id":"NTFILE2V2jAfZ8Xw8KpJmk","market":"us","size":117088},{"description":"EX-10.2 SECOND AMENDMENT","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex102_184.htm","primary":false,"translateUrl":null,"linkName":"apls-ex102_184.htm","type":"EX-10.2","id":"NTFILEH2FR2s7WdR3KgjBp","market":"us","size":49589},{"description":"EX-31.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex311_10.htm","primary":false,"translateUrl":null,"linkName":"apls-ex311_10.htm","type":"EX-31.1","id":"NTFILE5cfPrZjQ4aNYcXk8","market":"us","size":18215},{"description":"EX-31.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex312_6.htm","primary":false,"translateUrl":null,"linkName":"apls-ex312_6.htm","type":"EX-31.2","id":"NTFILEGxcREYZSZ3JTvC5L","market":"us","size":17557},{"description":"EX-32.1","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex321_9.htm","primary":false,"translateUrl":null,"linkName":"apls-ex321_9.htm","type":"EX-32.1","id":"NTFILEC2RBjJZ6J7doef4e","market":"us","size":8568},{"description":"EX-32.2","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-ex322_7.htm","primary":false,"translateUrl":null,"linkName":"apls-ex322_7.htm","type":"EX-32.2","id":"NTFILEH96W5PEpqN4jALF9","market":"us","size":8577},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/gdmlkae0ztv5000001.jpg","primary":false,"translateUrl":null,"linkName":"gdmlkae0ztv5000001.jpg","type":"GRAPHIC","id":"NTFILE5ZUbeHsjK82xbQCq","market":"us","size":24927},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-20190630.xsd","primary":false,"translateUrl":null,"linkName":"apls-20190630.xsd","type":"EX-101.SCH","id":"NTFILE4mEtAEiZwAJuQq4H","market":"us","size":34185},{"description":"XBRL TAXONOMY EXTENSION CALCULATION LINKBASE","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-20190630_cal.xml","primary":false,"translateUrl":null,"linkName":"apls-20190630_cal.xml","type":"EX-101.CAL","id":"NTFILE2B2udPimTVuE8iUS","market":"us","size":42596},{"description":"XBRL TAXONOMY EXTENSION DEFINITION LINKBASE","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-20190630_def.xml","primary":false,"translateUrl":null,"linkName":"apls-20190630_def.xml","type":"EX-101.DEF","id":"NTFILEHkyJ5kyGLTuErmyW","market":"us","size":88264},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-20190630_lab.xml","primary":false,"translateUrl":null,"linkName":"apls-20190630_lab.xml","type":"EX-101.LAB","id":"NTFILE8qWuzzRPSTRNVJbM","market":"us","size":269785},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-20190630_pre.xml","primary":false,"translateUrl":null,"linkName":"apls-20190630_pre.xml","type":"EX-101.PRE","id":"NTFILE69TgtGaqhKTDe3KZ","market":"us","size":195815},{"description":"EXTRACTED XBRL INSTANCE DOCUMENT","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019027462/apls-10q_20190630_htm.xml","primary":false,"translateUrl":null,"linkName":"apls-10q_20190630_htm.xml","type":"XML","id":"NTFILE3AERN1pufhTqaLvZ","market":"us","size":396002}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2019-07-31 00:00","pubTimestamp":1564502400,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932983","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519178796-APLS","pdf_url":null,"pub_time":1561046400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 5.07","symbol":"APLS","title":"Current report, item 5.07","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519178796/0001193125-19-178796-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, item 5.07","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519178796/d766897d8k.htm","primary":true,"translateUrl":null,"linkName":"d766897d8k.htm","type":"8-K","id":"NTFILE2bk5ejBtg4oSkeRi","market":"us","size":28893}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-06-21 00:00","pubTimestamp":1561046400,"title_zh":"Current report, item 5.07","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932955","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519168507-APLS","pdf_url":null,"pub_time":1560096000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 1.01","symbol":"APLS","title":"Current report, item 1.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519168507/0001193125-19-168507-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, item 1.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519168507/d763096d8k.htm","primary":true,"translateUrl":null,"linkName":"d763096d8k.htm","type":"8-K","id":"NTFILE68marfbwkeU21ZNq","market":"us","size":18824}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-06-10 00:00","pubTimestamp":1560096000,"title_zh":"Current report, item 1.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932973","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465919031738-APLS","pdf_url":null,"pub_time":1558627200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"APLS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919031738/0001104659-19-031738-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919031738/a19-10613_3sc13ga.htm","primary":true,"translateUrl":null,"linkName":"a19-10613_3sc13ga.htm","type":"SC 13G/A","id":"NTFILEAnU4ifJ7C6VjECfM","market":"us","size":142680},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919031738/a19-10613_3ex99d1.htm","primary":false,"translateUrl":null,"linkName":"a19-10613_3ex99d1.htm","type":"EX-99.1","id":"NTFILE8Jx45zk37xyN6mia","market":"us","size":11886}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2019-05-24 00:00","pubTimestamp":1558627200,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932958","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019016638-APLS","pdf_url":null,"pub_time":1557158400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"APLS","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/0001564590-19-016638-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-10q_20190331.htm","primary":true,"translateUrl":null,"linkName":"apls-10q_20190331.htm","type":"10-Q","id":"NTFILE9Ma42wUBHZhtaXEW","market":"us","size":1470863},{"description":"EX-10.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex101_221.htm","primary":false,"translateUrl":null,"linkName":"apls-ex101_221.htm","type":"EX-10.1","id":"NTFILEHcBnc3SvYxS9g3NG","market":"us","size":583329},{"description":"EX-10.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex102_113.htm","primary":false,"translateUrl":null,"linkName":"apls-ex102_113.htm","type":"EX-10.2","id":"NTFILEB68ZwFvDMpJumbu5","market":"us","size":690388},{"description":"EX-10.3","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex103_168.htm","primary":false,"translateUrl":null,"linkName":"apls-ex103_168.htm","type":"EX-10.3","id":"NTFILE8yQvt9yTQeEdcuue","market":"us","size":26216},{"description":"EX-31.1","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex311_8.htm","primary":false,"translateUrl":null,"linkName":"apls-ex311_8.htm","type":"EX-31.1","id":"NTFILEFeJuef8XEik7yLAU","market":"us","size":18211},{"description":"EX-31.2","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex312_7.htm","primary":false,"translateUrl":null,"linkName":"apls-ex312_7.htm","type":"EX-31.2","id":"NTFILE8QS9gBUyBjvnP771","market":"us","size":17555},{"description":"EX-32.1","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex321_9.htm","primary":false,"translateUrl":null,"linkName":"apls-ex321_9.htm","type":"EX-32.1","id":"NTFILEBdmgdz4jjokAEkH3","market":"us","size":8567},{"description":"EX-32.2","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-ex322_6.htm","primary":false,"translateUrl":null,"linkName":"apls-ex322_6.htm","type":"EX-32.2","id":"NTFILE63zDkDffaFn4GBc7","market":"us","size":8576},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/gkurtgndusz3000001.jpg","primary":false,"translateUrl":null,"linkName":"gkurtgndusz3000001.jpg","type":"GRAPHIC","id":"NTFILEAj7jzdhbDAhVvV7y","market":"us","size":98445},{"description":"XBRL INSTANCE DOCUMENT","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331.xml","primary":false,"translateUrl":null,"linkName":"apls-20190331.xml","type":"EX-101.INS","id":"NTFILEGt5ydDzKG9oSA3FS","market":"us","size":306704},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331.xsd","primary":false,"translateUrl":null,"linkName":"apls-20190331.xsd","type":"EX-101.SCH","id":"NTFILEHXHZmpDyAuFkn7RM","market":"us","size":33322},{"description":"XBRL TAXONOMY EXTENSION CALCULATION LINKBASE","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331_cal.xml","primary":false,"translateUrl":null,"linkName":"apls-20190331_cal.xml","type":"EX-101.CAL","id":"NTFILE6o49Sjh83dhmNRzt","market":"us","size":42569},{"description":"XBRL TAXONOMY EXTENSION DEFINITION LINKBASE","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331_def.xml","primary":false,"translateUrl":null,"linkName":"apls-20190331_def.xml","type":"EX-101.DEF","id":"NTFILE8St14fzyXUGgimzC","market":"us","size":83766},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331_lab.xml","primary":false,"translateUrl":null,"linkName":"apls-20190331_lab.xml","type":"EX-101.LAB","id":"NTFILECb2oDJkZr6nasQiy","market":"us","size":257216},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000156459019016638/apls-20190331_pre.xml","primary":false,"translateUrl":null,"linkName":"apls-20190331_pre.xml","type":"EX-101.PRE","id":"NTFILE12hwCxMrMPnBBdAm","market":"us","size":185493}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2019-05-07 00:00","pubTimestamp":1557158400,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932967","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519104692-APLS","pdf_url":null,"pub_time":1554998400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 4.01 and 9.01","symbol":"APLS","title":"Current report, items 4.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519104692/0001193125-19-104692-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 4.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-16.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519104692/d733958dex161.htm","primary":true,"translateUrl":null,"linkName":"d733958dex161.htm","type":"EX-16.1","id":"NTFILEHmx7Nf59C58gyqy5","market":"us","size":3323},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519104692/d733958d8k.htm","primary":false,"translateUrl":null,"linkName":"d733958d8k.htm","type":"8-K","id":"NTFILEB32pmXoknzyjK6PM","market":"us","size":18220},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519104692/g733958g51l13.jpg","primary":false,"translateUrl":null,"linkName":"g733958g51l13.jpg","type":"GRAPHIC","id":"NTFILEEDMKUdxbHaigDDGw","market":"us","size":6902},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519104692/g733958g75g46.jpg","primary":false,"translateUrl":null,"linkName":"g733958g75g46.jpg","type":"GRAPHIC","id":"NTFILEBhWhB7SRGFNPMmeo","market":"us","size":6771}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-04-12 00:00","pubTimestamp":1554998400,"title_zh":"Current report, items 4.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932972","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465919016797-APLS","pdf_url":null,"pub_time":1553184000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"APLS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919016797/0001104659-19-016797-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919016797/a19-6990_3sc13ga.htm","primary":true,"translateUrl":null,"linkName":"a19-6990_3sc13ga.htm","type":"SC 13G/A","id":"NTFILEHhcoU9iR78241gSd","market":"us","size":148067},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919016797/a19-6990_3ex99d1.htm","primary":false,"translateUrl":null,"linkName":"a19-6990_3ex99d1.htm","type":"EX-99.1","id":"NTFILEAMvoD787zNSK93JZ","market":"us","size":11883}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2019-03-22 00:00","pubTimestamp":1553184000,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932975","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465919014546-APLS","pdf_url":null,"pub_time":1552406400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"APLS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919014546/0001104659-19-014546-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919014546/a19-6305_1sc13ga.htm","primary":true,"translateUrl":null,"linkName":"a19-6305_1sc13ga.htm","type":"SC 13G/A","id":"NTFILE9Bmng7PhvwHWg7wH","market":"us","size":142479},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000110465919014546/a19-6305_1ex99d1.htm","primary":false,"translateUrl":null,"linkName":"a19-6305_1ex99d1.htm","type":"EX-99.1","id":"NTFILECbQsdVmxVAHQUDc1","market":"us","size":11821}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2019-03-13 00:00","pubTimestamp":1552406400,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932952","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519067216-APLS","pdf_url":null,"pub_time":1551888000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 1.01, 8.01, and 9.01","symbol":"APLS","title":"Current report, items 1.01, 8.01, and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/0001193125-19-067216-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 1.01, 8.01, and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-1.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/d714508dex11.htm","primary":true,"translateUrl":null,"linkName":"d714508dex11.htm","type":"EX-1.1","id":"NTFILEPM7BNdpykMRBHSE7","market":"us","size":166581},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/d714508d8k.htm","primary":false,"translateUrl":null,"linkName":"d714508d8k.htm","type":"8-K","id":"NTFILE3RePPKpmVQ7qdLBr","market":"us","size":22637},{"description":"EX-5.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/d714508dex51.htm","primary":false,"translateUrl":null,"linkName":"d714508dex51.htm","type":"EX-5.1","id":"NTFILE2s7k5NyprBbT2G4o","market":"us","size":10161},{"description":"EX-99.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/d714508dex991.htm","primary":false,"translateUrl":null,"linkName":"d714508dex991.htm","type":"EX-99.1","id":"NTFILE9mvsJv1j2V7BL2M6","market":"us","size":8189},{"description":"GRAPHIC","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/g714508dsp46.jpg","primary":false,"translateUrl":null,"linkName":"g714508dsp46.jpg","type":"GRAPHIC","id":"NTFILEFPpB6FrjkzvsnHC1","market":"us","size":10938},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/g714508g0307211833650.jpg","primary":false,"translateUrl":null,"linkName":"g714508g0307211833650.jpg","type":"GRAPHIC","id":"NTFILE8Dg1NsW8AUtrtT9s","market":"us","size":1649},{"description":"GRAPHIC","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519067216/g714508g0307212322163.jpg","primary":false,"translateUrl":null,"linkName":"g714508g0307212322163.jpg","type":"GRAPHIC","id":"NTFILEBGXeZo7s73eA9w17","market":"us","size":3627}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-03-07 00:00","pubTimestamp":1551888000,"title_zh":"Current report, items 1.01, 8.01, and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932946","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519061627-APLS","pdf_url":null,"pub_time":1551628800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 8.01","symbol":"APLS","title":"Current report, item 8.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519061627/0001193125-19-061627-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, item 8.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519061627/d715878d8k.htm","primary":true,"translateUrl":null,"linkName":"d715878d8k.htm","type":"8-K","id":"NTFILEB82zxe2ZVrNeqeNF","market":"us","size":19031}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-03-04 00:00","pubTimestamp":1551628800,"title_zh":"Current report, item 8.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8932968","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519056171-APLS","pdf_url":null,"pub_time":1551283200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 1.01","symbol":"APLS","title":"Current report, item 1.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519056171/0001193125-19-056171-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, item 1.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1492422/000119312519056171/d693707d8k.htm","primary":true,"translateUrl":null,"linkName":"d693707d8k.htm","type":"8-K","id":"NTFILEB4yoJrCRd1RicjBY","market":"us","size":27845}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-02-28 00:00","pubTimestamp":1551283200,"title_zh":"Current report, item 1.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":15,"pageCount":15,"totalSize":294,"code":"91000000","status":"200"}]}}