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Aptevo Therapeutics

1.07

+0.03002.88%

Post-market: 1.04-0.0285-2.66%19:45 EST

Volume:1.05M

Turnover:1.12M

Market Cap:18.03M

PE:-0.01

High:1.11

Open:1.03

Low:1.03

Close:1.04

52wk High:109.80

52wk Low:1.00

Shares:16.85M

Float Shares:13.51M

Volume Ratio:1.59

T/O Rate:7.81%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-110.7786

EPS(LYR):-1,747.6642

ROE:-242.74%

ROA:-79.19%

PB:1.04

PE(LYR):0.00

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News

Aptevo Therapeutics Reports Strong Remission Rates and Safety for Mipletamig in Frontline AML Trial

Aptevo Therapeutics Director Grady Grant III Acquires Common Shares

Aptevo Therapeutics Unveils Preclinical Data for Trispecific Antibody APVO451 in Solid Tumors

Aptevo Therapeutics management to meet virtually with Roth Capital

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Therapeutics Reports Strong Remission Rates and Safety for Mipletamig in Frontline AML Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2590349514","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590349514?lang=en_us&edition=fundamental","pubTime":"2025-12-09 21:05","pubTimestamp":1765285520,"startTime":"0","endTime":"0","summary":"Aptevo Therapeutics Inc. has announced preliminary results from its ongoing Phase 1b/2 RAINIER clinical study evaluating mipletamig, a CD123 x CD3 bispecific molecule, in combination with azacitidine and venetoclax for newly diagnosed acute myeloid leukemia  patients unfit for intensive chemotherapy. The data, presented on December 8, 2025, at the American Society of Hematology  Annual Meeting, showed that across dose-optimization cohorts 1-3, 100% of patients remained free of cytokine release syndrome. The overall response rate among evaluable patients was 93%, with 87% achieving complete remission or complete remission with incomplete hematologic recovery, and 73% achieving complete remission. Additionally, 60% of MRD-evaluable patients who achieved remission were negative for minimal residual disease. The study is ongoing, with continued patient enrollment at additional dose levels.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligen","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nNDL4HxSrD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["APVO","BK4139"],"gpt_icon":0},{"id":"2583358535","title":"Aptevo Therapeutics Director Grady Grant III Acquires Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2583358535","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583358535?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:33","pubTimestamp":1762983215,"startTime":"0","endTime":"0","summary":"Grady Grant III, a director of Aptevo Therapeutics Inc., has reported the acquisition of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Aptevo Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on November 12, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251112:nNDL3QbFQN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["EBS","BK4139","BK4583","APVO"],"gpt_icon":0},{"id":"2582287188","title":"Aptevo Therapeutics Unveils Preclinical Data for Trispecific Antibody APVO451 in Solid Tumors","url":"https://stock-news.laohu8.com/highlight/detail?id=2582287188","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582287188?lang=en_us&edition=fundamental","pubTime":"2025-11-10 21:09","pubTimestamp":1762780170,"startTime":"0","endTime":"0","summary":"Aptevo Therapeutics Inc. has announced the first presentation of preclinical data for its new trispecific antibody candidate, APVO451. The data were presented at the Society for Immunotherapy of Cancer  Annual Meeting on November 8, 2025. APVO451 is designed to address immune suppression in the tumor microenvironment of hard-to-treat solid tumors, including urothelial, breast, and pancreatic cancers. The molecule targets nectin-4 on tumor cells and incorporates Aptevo's proprietary CRIS-7-derived CD3 binding domain to activate T cells, as well as engaging CD40 to restore the function of antigen-presenting cells. The company reported that APVO451 is advancing through ongoing preclinical studies with the goal of supporting future clinical development.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL9Bx6PL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["EBS","BK4139","BK4583","APVO"],"gpt_icon":0},{"id":"2581196470","title":"Aptevo Therapeutics management to meet virtually with Roth Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2581196470","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581196470?lang=en_us&edition=fundamental","pubTime":"2025-11-07 02:25","pubTimestamp":1762453523,"startTime":"0","endTime":"0","summary":"Virtual Meeting to be held on November 13-14 hosted by Roth Capital. Published first on TheFly – the ultimate source for real-time, market-moving b...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/aptevo-therapeutics-management-to-meet-virtually-with-roth-capital-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/aptevo-therapeutics-management-to-meet-virtually-with-roth-capital-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["APVO","BK4139"],"gpt_icon":0}],"pageSize":4,"totalPage":11,"pageCount":1,"totalSize":43,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/APVO\",params:#limit:6,delay:false,,,undefined,":[]}}