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Biohaven Pharmaceutical Holding Co Ltd.

21.98

-0.6400-2.83%

Volume:112.95K

Turnover:2.48M

Market Cap:2.24B

PE:-2.37

High:22.22

Open:22.00

Low:21.74

Close:22.62

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Overview Company News Filings

Merus, Biohaven Partner to Develop Bispecific Therapies for Cancers

MT Newswires Live

BRIEF-Merus And Biohaven Announce Collaboration To Co-Develop Three Novel Bispecific ADC Programs

Biohaven - Agreement Includes Two Merus Bispecific Programs Generated Using Biclonics Platform

THOMSON REUTERS

Biohaven Ltd - Co Is Responsible for Preclinical ADC Generation of Three Merus Bispecific Antibodies Under Mutually Agreed Research Plans

THOMSON REUTERS

Biohaven Ltd - Merus Will Receive an Upfront Payment and License Fee at ADC Candidate Nomination of First Program

THOMSON REUTERS

Merus and Biohaven Announce Collaboration to Co-Develop Three Novel Bispecific ADC Programs

Insider Buying: Biohaven Independent Director Bought US$1.0m Of Shares

Simply Wall St.

Company News for Jan 2, 2025

Biohaven rises 6.1%

Biohaven Advances in Immunotherapy: Significant IgG Reduction Achieved with BHV-1300, Gains Analyst Approval

Biohaven Price Target Maintained With a $59.00/Share by HC Wainwright & Co.

Is Biohaven Ltd. (BHVN) the Best Weight Loss Stock to Buy Now According to Hedge Funds?

Bernstein Reaffirms Their Buy Rating on Biohaven Ltd. (BHVN)

BRIEF-Biohaven Reports Phase 1 Degrader Data; Announces NDA Submission For Troriluzole In SCA

BUZZ-Biohaven rises on positive early-stage antibody drug trial results

Biohaven Says BHV-1300 Achieves 'Deep Lowering' of Targeted IgG During Early-Stage Trial

MT Newswires Live

Biohaven reports clinical, regulatory milestones across MoDE platform

Biohaven Ltd - Bhv-1300 Safe and Well Tolerated in Phase 1

THOMSON REUTERS

Biohaven Reports Positive Phase 1 Degrader Data, Achieving Deep Targeted Igg Reductions in the Lowest Subcutaneous Dose Tested; Announces Nda Submission for Troriluzole in SCA and Provides Other Key Program Updates

THOMSON REUTERS

Biohaven Reports Positive Phase 1 Degrader Data, Achieving Deep Targeted IgG Reductions in the Lowest Subcutaneous Dose Tested; Announces NDA Submission for Troriluzole in SCA and Provides Other Key Program Updates

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(NYSE: BHVN) andMerus N.V. 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While that only increased their holding size by 0.4%, it is still a big swing by our standards.The Last 12 Months Of Insider Transactions At Biohaven. While Biohaven insiders bought shares during the last year, they didn't sell. You can see a visual depiction of insider transactions  over the last 12 months, below. By clicking on the graph below, you can see the precise details of each insider transaction!For the purposes of this article, insiders are those individuals who report their t","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/insider-buying-biohaven-independent-director-100429662.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","LU1093756325.SGD","BHVN","LU1093756168.USD"],"gpt_icon":0},{"id":"2500946915","title":"Company News for Jan 2, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2500946915","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2500946915?lang=en_us&edition=fundamental","pubTime":"2025-01-02 16:39","pubTimestamp":1735807140,"startTime":"0","endTime":"0","summary":"United States Steel Corp.’s  shares jumped 9.5% following the news that Nippon Steel submitted a new acquisition proposal to the U.S. government to acquire the company.Shares of Biohaven Ltd.  advanced 4.4% after the company’s director John Childs disclosed a purchase of 29,000 shares.Sangamo Therapeutics Inc.’s  shares plummeted 56.4% after Pfizer Inc.  terminated the agreement with the company for co-developing hemophilia A gene therapy.Shares of Builders FirstSource Inc.  fell 0.3% as the housing market is facing weak supply trend in 2025.Want the latest recommendations from Zacks Investment Research?Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report. Sangamo Therapeutics, Inc.  : Free Stock Analysis Report. To read this article on Zacks.com click here.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/company-news-jan-2-2025-083900222.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0225284248.USD","LU0456855351.SGD","LU0306806265.USD","SG9999011175.SGD","IE00BBT3K403.USD","SG9999013999.USD","SGXZ57979304.SGD","SG9999003800.SGD","LU1883839398.USD","LU1894683264.USD","BK4516","LU0289739699.SGD","LU0234572021.USD","BK4568","SG9999002232.USD","IE00BLSP4239.USD","BK4588","PFE","BK4592","LU1093756168.USD","SG9999001176.SGD","LU0321505439.SGD","BK4585","BK4006","SGMO","LU1894683348.USD","LU0170899867.USD","BK4599","X","BHVN","IE00B19Z3B42.SGD","LU0122379950.USD","SG9999001176.USD","SG9999002224.SGD","BLDR","LU1057294990.SGD","BK4139","LU0058720904.USD","BK4534","IE000M9KFDE8.USD","IE00B19Z3581.USD","LU1093756325.SGD","LU1066053197.SGD","BK4007","IE00BLSP4452.SGD","LU0868494617.USD","LU1066051498.USD","LU0985481810.HKD","LU0321505868.SGD","BK4581"],"gpt_icon":1},{"id":"2495161689","title":"Biohaven rises 6.1%","url":"https://stock-news.laohu8.com/highlight/detail?id=2495161689","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2495161689?lang=en_us&edition=fundamental","pubTime":"2024-12-31 22:50","pubTimestamp":1735656626,"startTime":"0","endTime":"0","summary":"Biohaven (BHVN) is up 6.1%, or $2.17 to $37.95. Published first on TheFly – the ultimate source for real-time, market-moving breaking financial new...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/biohaven-rises-6-1?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/biohaven-rises-6-1?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU1093756168.USD","BK4139","BHVN","LU1093756325.SGD"],"gpt_icon":0},{"id":"2492921992","title":"Biohaven Advances in Immunotherapy: Significant IgG Reduction Achieved with BHV-1300, Gains Analyst Approval","url":"https://stock-news.laohu8.com/highlight/detail?id=2492921992","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492921992?lang=en_us&edition=fundamental","pubTime":"2024-12-18 03:23","pubTimestamp":1734463411,"startTime":"0","endTime":"0","summary":"On Monday, Biohaven Ltd.  revealed clinical and regulatory milestones across its proprietary Molecular Degrader of Extracellular Proteins  platform and its glutamate modulation and ion channel programs.Immunoglobulin G  isa protein that helps prevent infections and is the most common type of antibody in the body. Elevated IgG levels can be seen in chronic active infection or inflammation.Subcutaneously administered BHV-1300 achieved deep lowering of targeted IgG, with reductions >60% in the lowest subcutaneous dose tested in the ongoing multiple ascending dose  study.William Blair highlights that greater than 60% was the minimum efficacy bar for IgG reductions based on comparable data from argenx Inc's  subcutaneous efgartigimod, which showed a mean total IgG reduction of 66.4% from baseline at day 29 but is not currently available in an autoinjector formulation.Also Read: Biohaven Stock Spikes After Drug Candidate To Treat Rare Neurodegenerative Disease Shows Promise. Escalating dose ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/jixIN0XKvSsaFCN7J9kiYA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/88d1bb1cedb1cd4380fbdf7d29775094","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/jixIN0XKvSsaFCN7J9kiYA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/88d1bb1cedb1cd4380fbdf7d29775094"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biohaven-advances-immunotherapy-significant-igg-192331593.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2111349929.HKD","LU0106261372.USD","LU1668664300.SGD","LU0098860793.USD","BK4139","LU1074936037.SGD","LU1989772840.SGD","BK4505","LU0320765646.SGD","BK4127","ARGX","LU1989772923.USD","LU2089284900.SGD","LU0225283273.USD","LU0889565916.HKD","BK4581","LU0971096721.USD","LU1093756168.USD","LU0106831901.USD","LU0267386448.USD","LU1093756325.SGD","LU0158827948.USD","LU1162221912.USD","LU1363072403.SGD","LU2357305700.SGD","BK4534","LU0006306889.USD","LU1720051108.HKD","LU1548497426.USD","BK4516","IE00BZ1G4Q59.USD","LU2023251221.USD","BK4585","LU0158827781.USD","BHV","IE00BKVL7J92.USD","LU2089283258.USD","LU2271345857.HKD","LU0320765992.SGD","LU1720051017.SGD","LU0109394709.USD","BK4588","LU0314104364.USD","BHVN","LU2028103732.USD","BK4504"],"gpt_icon":0},{"id":"2492293007","title":"Biohaven Price Target Maintained With a $59.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2492293007","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492293007?lang=en_us&edition=fundamental","pubTime":"2024-12-17 19:31","pubTimestamp":1734435060,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BHVN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 17, 2024 06:31 ET (11:31 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BHVN"],"gpt_icon":0},{"id":"2492930108","title":"Is Biohaven Ltd. (BHVN) the Best Weight Loss Stock to Buy Now According to Hedge Funds?","url":"https://stock-news.laohu8.com/highlight/detail?id=2492930108","media":"Insider Monkey","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492930108?lang=en_us&edition=fundamental","pubTime":"2024-12-17 19:06","pubTimestamp":1734433613,"startTime":"0","endTime":"0","summary":"We recently compiled a list of the 12 Best Weight Loss Stocks to Buy According to Hedge Funds.In this article, we are going to take a look at where Biohaven Ltd.  stands against the other weight loss stocks.The Revolution in Obesity Treatment: Opportunities and Challenges of GLP-1 Medications. Given this increase in demand, Morgan Stanley Research has raised its forecast for the worldwide obesity medication market from $77 billion to $105 billion by 2030. Branded obesity medications brought approximately $6 billion in 2023.By 2030, the GLP-1 market is expected to grow to $100 billion, driven equally by obesity and diabetes, according to JP Morgan Research. Thirty million GLP-1 users, or around 9% of the population, may be in the US by 2030. The rising demand for obesity drugs will have a broad effect, helping industries like biotech but creating challenges for others like the food and beverage industry.According to Chris Schott, a Senior Analyst specializing in the U.S. Diversified Bio","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/gUz9HDzH4plaJj0_SE7bmQ--~B/aD04MTY7dz0xNDU2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/insidermonkey.com/2d1436f3ebd76fdb45ce5da9242e82b8","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/gUz9HDzH4plaJj0_SE7bmQ--~B/aD04MTY7dz0xNDU2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/insidermonkey.com/2d1436f3ebd76fdb45ce5da9242e82b8"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biohaven-ltd-bhvn-best-weight-110653262.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4504","LU1074936037.SGD","LU0158827781.USD","LU1720051108.HKD","LU2089283258.USD","LU1363072403.SGD","BK4139","IE00BKVL7J92.USD","LU2028103732.USD","LU0098860793.USD","LU0106261372.USD","LU1093756168.USD","LU0267386448.USD","LU1548497426.USD","LU2271345857.HKD","BK4585","LU0314104364.USD","LU0158827948.USD","BK4588","BK4127","IE00BZ1G4Q59.USD","LU1668664300.SGD","BK4534","LU2357305700.SGD","LU1720051017.SGD","LU0106831901.USD","BK4516","LU2111349929.HKD","BHVN","BK4581","LU0006306889.USD","LU1989772923.USD","LU1989772840.SGD","LU2023251221.USD","LU0971096721.USD","LU0225283273.USD","LU2089284900.SGD","LU0320765646.SGD","LU1162221912.USD","LU1093756325.SGD"],"gpt_icon":0},{"id":"2492793436","title":"Bernstein Reaffirms Their Buy Rating on Biohaven Ltd. (BHVN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2492793436","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492793436?lang=en_us&edition=fundamental","pubTime":"2024-12-17 08:59","pubTimestamp":1734397165,"startTime":"0","endTime":"0","summary":"Bernstein analyst William Pickering maintained a Buy rating on Biohaven Ltd. (BHVN – Research Report) yesterday and set a price target of $63.00. T...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/bernstein-reaffirms-their-buy-rating-on-biohaven-ltd-bhvn?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/bernstein-reaffirms-their-buy-rating-on-biohaven-ltd-bhvn?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BHVN"],"gpt_icon":0},{"id":"2491696699","title":"BRIEF-Biohaven Reports Phase 1 Degrader Data; Announces NDA Submission For Troriluzole In SCA","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696699","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696699?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:34","pubTimestamp":1734356082,"startTime":"0","endTime":"0","summary":"Dec 16  - Biohaven Ltd   :   * BIOHAVEN REPORTS POSITIVE PHASE 1 DEGRADER DATA, ACHIEVING DEEP TARGETED IGG REDUCTIONS IN THE LOWEST SUBCUTANEOUS DOSE TESTED; ANNOUNCES NDA SUBMISSION FOR TRORILUZOLE IN SCA AND PROVIDES OTHER KEY PROGRAM UPDATES   * BHV-1300 SAFE AND WELL TOLERATED IN PHASE 1Source text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SCA","BK4139","LU1093756168.USD","LU1093756325.SGD","BHVN"],"gpt_icon":0},{"id":"2491696342","title":"BUZZ-Biohaven rises on positive early-stage antibody drug trial results","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696342","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696342?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:33","pubTimestamp":1734356024,"startTime":"0","endTime":"0","summary":"** Shares of drug developer Biohaven    rise 2.7% to $39.5 premarket   ** BHVN says its experimental drug, BHV-1300, reduced targeted Immunoglobulin G, a type of antibody, by more than 60% in an early-stage clinical trial   ** BHVN partnered with Ypsomed to develop an autoinjector for BHV-1300, co says   ** All 15 brokerages rate the stock \"buy\" or higher; their median PT is $63 - LSEG   ** As of last close, stock has fallen ~10% YTD ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"BUZZ-Biohaven rises on positive early-stage antibody drug trial results","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BHVN","LU1093756168.USD","LU1093756325.SGD"],"gpt_icon":0},{"id":"2491696390","title":"Biohaven Says BHV-1300 Achieves 'Deep Lowering' of Targeted IgG During Early-Stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696390","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696390?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:32","pubTimestamp":1734355927,"startTime":"0","endTime":"0","summary":"Biohaven (BHVN) said Monday that its drug candidate BHV-1300 achieved \"deep lowering\" of targeted immunoglobulin G, or IgG, with reduction of more than 60% in the lowest subcutaneous dose tested durin","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU1093756325.SGD","BHV","BK4139","BHVN","SSI","LU1093756168.USD"],"gpt_icon":0},{"id":"2491938686","title":"Biohaven reports clinical, regulatory milestones across MoDE platform","url":"https://stock-news.laohu8.com/highlight/detail?id=2491938686","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491938686?lang=en_us&edition=fundamental","pubTime":"2024-12-16 20:45","pubTimestamp":1734353129,"startTime":"0","endTime":"0","summary":"Biohaven (BHVN) highlighted the achievement of several clinical and regulatory milestones across its proprietary Molecular Degrader of Extracellula...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/biohaven-reports-clinical-regulatory-milestones-across-mode-platform?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/biohaven-reports-clinical-regulatory-milestones-across-mode-platform?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU1093756325.SGD","BHVN","BK4139","LU1093756168.USD"],"gpt_icon":0},{"id":"2491866014","title":"Biohaven Ltd - Bhv-1300 Safe and Well Tolerated in Phase 1","url":"https://stock-news.laohu8.com/highlight/detail?id=2491866014","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491866014?lang=en_us&edition=fundamental","pubTime":"2024-12-16 20:30","pubTimestamp":1734352206,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nTUA89PDHK:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU1093756168.USD","BK4139","BHVN","LU1093756325.SGD"],"gpt_icon":0},{"id":"2491366011","title":"Biohaven Reports Positive Phase 1 Degrader Data, Achieving Deep Targeted Igg Reductions in the Lowest Subcutaneous Dose Tested; 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Announces NDA Submission for Troriluzole in SCA and Provides Other Key Program Updates","url":"https://stock-news.laohu8.com/highlight/detail?id=2491693118","media":"PR Newswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491693118?lang=en_us&edition=fundamental","pubTime":"2024-12-16 20:30","pubTimestamp":1734352200,"startTime":"0","endTime":"0","summary":"BHV-1300 achieved deep lowering of targeted IgG, with reductions > 60% in the lowest subcutaneous dose tested in the MAD.Subcutaneous BHV-1300 achieved rapid and progressive lowering ofIgG within hours of each weekly dose administration, and pharmacodynamic effects were sustained relative to baseline over the four-week period. The optimized subcutaneous formulation also showed substantially less inter-patient variability in the MAD compared to the previously reported intravenously administered BHV-1300.BHV-1300 has been safe and well tolerated across the ongoing Phase 1 without any dose limiting toxicity to date. AllAEs have been mild, with no SAEs or discontinuations related to study drug. Dose escalation continues with the optimized subcutaneous formulation to explore the full range of IgG reductions possible with BHV-1300. 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