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Castle Biosciences, Inc.

20.05

+0.20001.01%

Post-market: 20.050.00000.00%19:35 EDT

Volume:394.18K

Turnover:7.83M

Market Cap:578.34M

PE:32.34

High:20.12

Open:19.78

Low:19.35

Close:19.85

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Overview Company News Filings

BRIEF-Castle Biosciences Q4 Revenue USD 86.311 Million Vs. IBES Estimate USD 81.9 Million

Castle Biosciences Inc - Expects 2025 Revenue Between $280-295 Million

THOMSON REUTERS

Castle Biosciences Inc FY2025 REV View $274.1 Mln -- Lseg Ibes Data

THOMSON REUTERS

Castle Biosciences Reports Fourth Quarter and Full-Year 2024 Results

Castle Biosciences to Participate in Upcoming Investor Conferences

CSTL Gears Up to Report Q4 Earnings: Here's What You Should Know

Surging Earnings Estimates Signal Upside for Castle Biosciences (CSTL) Stock

Are Medical Stocks Lagging Adaptive Biotechnologies (ADPT) This Year?

IMVT Q3 Loss Wider Than Expected, Stock Down, Pipeline in Focus

DNLI Reports Upbeat Longer-Term Data From Hunter Syndrome Study

Insmed's NDA for Lung Disease Drug Gets FDA's Priority Review

RZLT Shares Rise 30.8% in 6 Months: What's Driving the Rally?

GHRS Stock Rallies 55% in a Week: Here's What You Should Know

VKTX's Q4 Loss Wider Than Expected, Sales Nil, Stock Down 10%

PFE's Colorectal Cancer Drug Meets Other Dual Primary Goal of PFS

Biogen Stock Down on Regulatory Update in the EU for Alzheimer's Drug

Strong week for Castle Biosciences (NASDAQ:CSTL) shareholders doesn't alleviate pain of three-year loss

Simply Wall St.

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FDA Clears Allogene's IND for CAR T Therapy in Autoimmune Diseases

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IBES Estimate USD 81.9 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2514301833","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514301833?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:05","pubTimestamp":1740690346,"startTime":"0","endTime":"0","summary":"Feb 27  - Castle Biosciences Q4 operating income USD 4.05 million.Q4 net income USD 9.59 million vs. IBES estimate USD 1.18 million. Q4 pretax profit USD 7.885 million vs. IBES estimate USD 2.92 million","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nPLXA53D68:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CSTL"],"gpt_icon":0},{"id":"2514358158","title":"Castle Biosciences Inc - Expects 2025 Revenue Between $280-295 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2514358158","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514358158?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:05","pubTimestamp":1740690301,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nPLXA53D68:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["CSTL","BK4196"],"gpt_icon":0},{"id":"2514358132","title":"Castle Biosciences Inc  FY2025 REV View $274.1 Mln -- Lseg Ibes Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2514358132","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514358132?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:05","pubTimestamp":1740690301,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nPLXA53D68:7","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["CSTL","BK4196"],"gpt_icon":0},{"id":"2514581253","title":"Castle Biosciences Reports Fourth Quarter and Full-Year 2024 Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2514581253","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514581253?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:05","pubTimestamp":1740690300,"startTime":"0","endTime":"0","summary":"Full-year 2024 revenue of $332 million, an increase of 51% compared to 2023 and above previously reported guidance. Delivered 96,071 total test reports in 2024, an increase of 36% compared to 2023. Year-end 2024 cash, cash equivalents and marketable investment securities of $293 million, a $50 million increase compared to 2023. Anticipate generating between $280-295 million in total revenue in 2025. FRIENDSWOOD, Texas, February 27, 2025----Castle Biosciences, Inc. , a company improving health through innovative tests that guide patient care, today announced its financial results for the fourth quarter and year ended December 31, 2024.\"Castle delivered an outstanding fourth quarter that rounded out an exceptional 2024, including 51% revenue growth and 36% test report volume growth compared to 2023,\" said Derek Maetzold, president and chief executive officer of Castle Biosciences. \"I am incredibly proud of our team's hard work in achieving these results, including achieving our previousl","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/castle-biosciences-reports-fourth-quarter-210500778.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BE","LU0476273544.USD","BK4588","LU1642822529.SGD","LU0823414551.USD","LU0444973449.USD","LU2294711713.HKD","BK4196","BK4207","CM","LU0823414478.USD","SCC","LU2506951792.HKD","LU2249611893.SGD","CSTL","LU0444971666.USD","LU0957808578.USD","BK4182","BK4541","LU1815336760.USD","LU2357125470.USD","BK4585"],"gpt_icon":0},{"id":"2514822047","title":"Castle Biosciences to Participate in Upcoming Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2514822047","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514822047?lang=en_us&edition=fundamental","pubTime":"2025-02-26 05:30","pubTimestamp":1740519000,"startTime":"0","endTime":"0","summary":"FRIENDSWOOD, Texas, February 25, 2025----Castle Biosciences, Inc. , a company improving health through innovative tests that guide patient care, today announced that its executive management is scheduled to present a company overview at the following investor conferences next month:. Leerink Partners Global Healthcare Conference on March 10, 2025, at 1:40 p.m. Eastern time.KeyBanc Capital Markets Healthcare Forum, occurring virtually on March 18, 2025, at 11:15 a.m. Eastern time.Castle Biosciences  is a leading diagnostics company improving health through innovative tests that guide patient care. The Company aims to transform disease management by keeping people first: patients, clinicians, employees and investors.DecisionDx-Melanoma, DecisionDx-CMSeq, i31-SLNB, i31-ROR, DecisionDx-SCC, MyPath Melanoma, DiffDx-Melanoma, TissueCypher, IDgenetix, DecisionDx-UM, DecisionDx-PRAME and DecisionDx-UMSeq are trademarks of Castle Biosciences, Inc.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/castle-biosciences-participate-upcoming-investor-213000895.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4196","CSTL"],"gpt_icon":0},{"id":"2514772352","title":"CSTL Gears Up to Report Q4 Earnings: Here's What You Should Know","url":"https://stock-news.laohu8.com/highlight/detail?id=2514772352","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514772352?lang=en_us&edition=fundamental","pubTime":"2025-02-25 00:42","pubTimestamp":1740415320,"startTime":"0","endTime":"0","summary":"Castle Biosciences, Inc. CSTL is scheduled to report fourth-quarter and full-year 2024 results on Feb. 27, after market close. The Zacks Consensus Estimate for the to-be-reported quarter’s revenues is pegged at $85.7 million, while the same for earnings is pinned at 11 cents per share.Find the latest EPS estimates and surprises on ZacksEarnings Calendar.In the past year, shares of Castle Biosciences have increased 5.1% against the industry’s decline of 8.7%.Castle Biosciences offers innovative test solutions to help clinicians diagnose and treat dermatologic cancers, Barrett’s esophagus , uveal melanoma  and mental health conditions.Last month, Castle Biosciences reported preliminary results for the fourth quarter of 2024. The company delivered 24,071 total test reports in the fourth quarter of 2024.Castle Biosciences has an excellent history of earnings surprises. The company beat on earnings in each of the trailing four quarters, delivering an average surprise of 172.72%. In the last","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cstl-gears-report-q4-earnings-164200241.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL"],"gpt_icon":0},{"id":"2511585484","title":"Surging Earnings Estimates Signal Upside for Castle Biosciences (CSTL) Stock","url":"https://stock-news.laohu8.com/highlight/detail?id=2511585484","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511585484?lang=en_us&edition=fundamental","pubTime":"2025-02-13 01:20","pubTimestamp":1739380805,"startTime":"0","endTime":"0","summary":"Castle Biosciences, Inc.  appears an attractive pick given a noticeable improvement in the company's earnings outlook. The stock has been a strong performer lately, and the momentum might continue with analysts still raising their earnings estimates for the company.Analysts' growing optimism on the earnings prospects of this company is driving estimates higher, which should get reflected in its stock price. After all, empirical research shows a strong correlation between trends in earnings estimate revisions and near-term stock price movements. This insight is at the core of our stock rating tool -- the Zacks Rank.The five-grade Zacks Rank system, which ranges from a Zacks Rank #1  to a Zacks Rank #5 , has an impressive externally-audited track record of outperformance, with Zacks #1 Ranked stocks generating an average annual return of +25% since 2008.For Castle Biosciences, there has been strong agreement among the covering analysts in raising earnings estimates, which has helped push","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/surging-earnings-estimates-signal-upside-172005769.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL"],"gpt_icon":0},{"id":"2511028313","title":"Are Medical Stocks Lagging  Adaptive Biotechnologies (ADPT) This Year?","url":"https://stock-news.laohu8.com/highlight/detail?id=2511028313","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511028313?lang=en_us&edition=fundamental","pubTime":"2025-02-12 22:40","pubTimestamp":1739371210,"startTime":"0","endTime":"0","summary":"For those looking to find strong Medical stocks, it is prudent to search for companies in the group that are outperforming their peers. Adaptive Biotechnologies  is a stock that can certainly grab the attention of many investors, but do its recent returns compare favorably to the sector as a whole?A quick glance at the company's year-to-date performance in comparison to the rest of the Medical sector should help us answer this question.Adaptive Biotechnologies is one of 1011 companies in the Medical group. The Medical group currently sits at #3 within the Zacks Sector Rank. The Zacks Sector Rank considers 16 different sector groups. The average Zacks Rank of the individual stocks within the groups is measured, and the sectors are listed from best to worst.The Zacks Rank is a proven model that highlights a variety of stocks with the right characteristics to outperform the market over the next one to three months. The system emphasizes earnings estimate revisions and favors companies wit","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/medical-stocks-lagging-adaptive-biotechnologies-144010220.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4121","BK4196","CSTL","ADPT"],"gpt_icon":0},{"id":"2509725357","title":"IMVT Q3 Loss Wider Than Expected, Stock Down, Pipeline in Focus","url":"https://stock-news.laohu8.com/highlight/detail?id=2509725357","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509725357?lang=en_us&edition=fundamental","pubTime":"2025-02-07 23:09","pubTimestamp":1738940940,"startTime":"0","endTime":"0","summary":"Immunovant, Inc.IMVT reported third-quarter fiscal 2025 net loss of 76 cents per share, wider than the Zacks Consensus Estimate of a loss of 73 cents. The reported figure is also wider than the year-ago quarter's loss of 36 cents per share.See the ZacksEarnings Calendar to stay ahead of market-making news.Currently, Immunovant does not have any approved product in its portfolio. As a result, it is yet to generate revenues.The stock declined 9.6% following the lower-than-expected earnings results.Research and development (R&D) expenses totaled $94.5 million, up 96% from the year-ago quarter’s figure. The massive uptick can be attributed to activities in preparation for potential future clinical studies of IMVT-1402, including contract manufacturing costs for drug substance, higher overall clinical study costs related to batoclimab development programs and increased personnel-related expenses.The broad set of late-stage studies expected to be initiated for IMVT-1402 will include several ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/imvt-q3-loss-wider-expected-150900575.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","LU0170899867.USD","BK4548","IE00B7SZL793.SGD","BK4139","IE00B66KJ199.SGD","GD","ALNY","BMRN","IE00B19Z3581.USD","CSTL","IE00B7SZLL34.SGD","BK4123","IE00B19Z4B17.USD","IE00B19Z3B42.SGD","BK4566","BK4196","IE0031619046.USD","MG","IE0002270589.USD","IMVT","BK4516","BK4550","BK4187","BK4588"],"gpt_icon":0},{"id":"2509801725","title":"DNLI Reports Upbeat Longer-Term Data From Hunter Syndrome Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2509801725","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509801725?lang=en_us&edition=fundamental","pubTime":"2025-02-07 22:54","pubTimestamp":1738940040,"startTime":"0","endTime":"0","summary":"Denali TherapeuticsDNLI reported primary analysis data from an early to mid-stage study of its pipeline candidate, tividenofusp alfa , in 47 patients with Hunter syndrome  over a 24-week treatment period, along with additional long-term follow-up data. DNLI’s wholly-owned program, tividenofusp alfa, is an Enzyme Transport Vehicle-enabled iduronate-2-sulfatase replacement therapy in development for MPS II.Per the additional long-term data readout from the phase I/II study, treatment with tividenofusp alfa resulted in significant and substantial reductions in key disease biomarkers within the central nervous system and peripheral system, bringing them to normal or near-normal levels. Such biomarkers included cerebrospinal fluid and urine heparan sulfate, as well as neurofilament light, a recognized marker of neurodegeneration.Per Denali, such efficacy data suggests the pervasive nature of treatment effects in MPS II patients over the longer term.Shares of DNLI have plunged 28.1% in the p","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/dnli-reports-upbeat-longer-term-145400778.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00B19Z3B42.SGD","IE00B19Z3581.USD","BK4585","BK4566","DNLI","IE00B7SZLL34.SGD","BK4588","ALNY","BMRN","BK4535","BK4139","CSTL","IE0002270589.USD","BK4548","BK4196"],"gpt_icon":0},{"id":"2509747047","title":"Insmed's NDA for Lung Disease Drug Gets FDA's Priority Review","url":"https://stock-news.laohu8.com/highlight/detail?id=2509747047","media":"Zacks","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509747047?lang=en_us&edition=fundamental","pubTime":"2025-02-07 21:53","pubTimestamp":1738936380,"startTime":"0","endTime":"0","summary":"Insmed Incorporated INSM announced that the FDA has accepted its new drug application  seeking approval of its reversible inhibitor of dipeptidyl peptidase 1 , brensocatib, for treating patients with non-cystic fibrosis bronchiectasis.With the FDA granting a priority review to the NDA, a decision from the regulatory body is expected on Aug. 12, 2025.If approved, brensocatib will become the first and only approved treatment for bronchiectasis, a chronic lung disease with no approved treatments. It would also become the first DPP1 inhibitor to be approved for the treatment of neutrophil-mediated diseases.Last month, the company outlined key pipeline goals for 2025. At the time, management stated that upon approval, it expects to launch brensocatib in the United States in the third quarter of 2025.In the past year, shares of Insmed have skyrocketed 182.7% against the industry’s decline of 6.5%.INSM's Brensocatib NDA Based on Data from ASPEN Study. The latest NDA was based on data from the","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/insmeds-nda-lung-disease-drug-135300938.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL","ARGX","LU0320765992.SGD","BK4007","HRMY","LU0109394709.USD","BK4505","LU0889565916.HKD","BK4588","LU0053671581.USD","INSM","BK4139","BK4196","BK4585"],"gpt_icon":0},{"id":"2509209101","title":"RZLT Shares Rise 30.8% in 6 Months: What's Driving the Rally?","url":"https://stock-news.laohu8.com/highlight/detail?id=2509209101","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509209101?lang=en_us&edition=fundamental","pubTime":"2025-02-06 23:35","pubTimestamp":1738856100,"startTime":"0","endTime":"0","summary":"Shares of Rezolute RZLT have rallied 30.8% in the past six months against the industry’s decline of 4.1%, driven by investor enthusiasm about the company’s encouraging progress with the development activities for its lead pipeline candidate, ersodetug .Rezolute is a late-stage clinical biotech focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism .The company is evaluating ersodetug in the phase III sunRIZE study for treating patients with congenital HI, an ultra-rare pediatric genetic disorder.An independent Data Monitoring Committee  reviewed the OLA of the sunRIZE study, which evaluated ersodetug in eight infants aged between three months to one year for treating congenital HI. Per the DMC review, treatment with ersodetug was generally safe and well-tolerated in the given patient population. The DMC also approved the enrollment of subsequent infants into the double-blind portion of the study.Some better-ranked stocks in the biotech sector are Harm","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/rzlt-shares-rise-30-8-153500425.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BMRN","IE00B19Z3581.USD","LU2360032135.SGD","IE0002270589.USD","BK4139","LU0128526141.USD","BK4161","IE00B19Z3B42.SGD","HRMY","LU2125154935.USD","HI","IE00B7SZLL34.SGD","LU2125154778.USD","LU0029874061.USD","BK4566","RZLT","BK4196","BK4007","CSTL"],"gpt_icon":0},{"id":"2509209176","title":"GHRS Stock Rallies 55% in a Week: Here's What You Should Know","url":"https://stock-news.laohu8.com/highlight/detail?id=2509209176","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509209176?lang=en_us&edition=fundamental","pubTime":"2025-02-06 23:25","pubTimestamp":1738855500,"startTime":"0","endTime":"0","summary":"Shares of GH Research PLC GHRS have rallied 54.8% in a week after the company, on Feb. 3, 2025, announced that it has met the primary goal in a mid-stage study of its investigational, inhalable mebufotenin product candidate, GH001, to treat patients with treatment-resistant depression .Per the data readout from the phase IIb TRD study, 40 patients treated with GH001 achieved a significant 15.2-point reduction in Montgomery-sberg Depression Rating Scale  score by Day 8, while the placebo group, comprising 41 patients, showed a slight increase of 0.3 points. Please note that MADRS is a metric showing the improvement of depressive symptoms in patients compared with placebo after the treatment period.It was observed that most patients receiving GH001 achieved remission with a 57.5% remission rate on Day 8 compared with 0% in the placebo group. Furthermore, in the open-label extension  portion of the phase IIb study, TRD patients who had remission on Day 8 after their first dosage had a 91.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ghrs-stock-rallies-55-week-152500374.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4539","ALNY","IE00B19Z3581.USD","BK4548","IE00B19Z3B42.SGD","BK4566","BK4585","GHRS","BK4588","IE00B7SZLL34.SGD","IE0002270589.USD","BK4139","CSTL","BK4007","BMRN","BK4196"],"gpt_icon":0},{"id":"2509127762","title":"VKTX's Q4 Loss Wider Than Expected, Sales Nil, Stock Down 10%","url":"https://stock-news.laohu8.com/highlight/detail?id=2509127762","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509127762?lang=en_us&edition=fundamental","pubTime":"2025-02-06 21:25","pubTimestamp":1738848300,"startTime":"0","endTime":"0","summary":"Viking Therapeutics VKTX reported a fourth-quarter 2024 loss per share of 32 cents, wider than the Zacks Consensus Estimate of a loss of 27 cents. The company had incurred a loss of 25 cents per share in the year-ago quarter.See the Zacks Earnings Calendar to stay ahead of market-making news.Currently, Viking Therapeutics does not have any approved products in its portfolio. Hence, it is yet to generate revenues.Research and development expenses surged 51% year over year to $31 million. This uptick was mainly due to increased manufacturing expenses for the company’s drug candidates, along with higher employee-related costs.As of Dec. 31, 2024, Viking Therapeutics had cash, cash equivalents and short-term investments worth $903 million compared with $930 million as of Sept. 30, 2024.VKTX is currently evaluating the potential next steps for VK2809, which completed the phase IIb VOYAGE study last year. Overall data from the study showed that 40-50% of patients who received the drug achiev","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/vktxs-q4-loss-wider-expected-132500799.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL","VKTX"],"gpt_icon":1},{"id":"2509466090","title":"PFE's Colorectal Cancer Drug Meets Other Dual Primary Goal of PFS","url":"https://stock-news.laohu8.com/highlight/detail?id=2509466090","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509466090?lang=en_us&edition=fundamental","pubTime":"2025-02-04 22:26","pubTimestamp":1738679160,"startTime":"0","endTime":"0","summary":"PfizerPFE announced positive top-line results from the progression-free survival  analysis of a late-stage study of its oncology drug, Braftovi , for treating patients with metastatic colorectal cancer  harboring a BRAF V600E mutation. Braftovi is an oral small-molecule kinase inhibitor that targetsBRAF V600E.The phase III BREAKWATER study is evaluating the candidate's safety and efficacy in combination with Eli Lilly’s LLY Erbitux  and chemotherapy  in mCRC patients harboring a BRAF V600E mutation.BRAF mutations are found in 8-12% of mCRC cases and are linked to a poorer prognosis. The BRAF V600E mutation is the most common and more than doubles the risk of death compared to patients without any mutation. Despite the high unmet need, no biomarker-driven therapies were approved for previously untreated BRAF V600E-mutant mCRC until December 2024. Thus, Pfizer has the first-mover advantage in t","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pfes-colorectal-cancer-drug-meets-142600063.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0640476718.USD","LU1093756325.SGD","LLY","LU1066053197.SGD","IE00BBT3K403.USD","LU1868836757.USD","LU1023059063.AUD","LU0868494617.USD","LU2361044949.HKD","PFS","LU0097036916.USD","LU0354030438.USD","LU2361045086.USD","LU1291159041.SGD","ALNY","CSTL","IE00BK4W5M84.HKD","PFE","BK4581","IE00B19Z3B42.SGD","BK4516","LU0170899867.USD","LU0238689110.USD","LU0882574055.USD","LU1623119135.USD","LU1127390331.HKD","LU2491050154.USD","LU0114720955.EUR","LU1064131342.USD","LU1720051017.SGD","BK4007","LU1066051498.USD","LU1894683264.USD","LU2491049909.HKD","LU2237443895.HKD","BK4534","BK4588","LU2361044865.SGD","LU0079474960.USD","LU0306806265.USD","LU0471298694.HKD","SG9999002232.USD","LU0823416689.USD","ORR","IE0002141913.USD","LU2106854487.HKD","LU2324357040.USD","LU2237438978.USD","LU1280957306.USD","SGXZ99366536.SGD"],"gpt_icon":1},{"id":"2508746140","title":"Biogen Stock Down on Regulatory Update in the EU for Alzheimer's Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2508746140","media":"Zacks","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508746140?lang=en_us&edition=fundamental","pubTime":"2025-02-03 22:31","pubTimestamp":1738593060,"startTime":"0","endTime":"0","summary":"BiogenBIIB and Japan-based partner, Eisai, announced an update regarding the regulatory review of an application seeking the approval of Leqembi  for mild cognitive impairment due to Alzheimer’s disease  and mild AD, collectively known as early AD, in the EU.Please note that, in November 2024, the European Medicines Agency’s  Committee for Medicinal Products for Human Use  rendered a positive opinion recommending marketing approval for Leqembi for early AD.Biogen and Eisai announced that the European Commission  has requested the CHMP to reassess new safety data that emerged after the positive opinion and determine if any updates are needed. Additionally, the CHMP will review the clarity of risk minimization measures in its opinion to ensure proper implementation. These discussions are scheduled for an upcoming CHMP meeting later this month.BIIB stock lost 1.6% on Friday following the news. Shares of Biogen have plunged 17.1% in the past three months compared with theindustry’s decline","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biogen-stock-down-regulatory-eu-143100317.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BFTCPJ56.SGD","LU0820561818.USD","SG9999014898.SGD","LU0943347566.SGD","LU2211815571.USD","LU1366192091.USD","LU1720051108.HKD","LLY","LU1623119135.USD","IE0009355771.USD","CHMP","BK4201","LU1061106388.HKD","LU0471298777.SGD","LU2237443382.USD","LU1093756325.SGD","LU1069344957.HKD","LU0354030438.USD","LU1548497426.USD","LU2265009873.SGD","LU0689472784.USD","LU2361044865.SGD","BK4139","LU1280957306.USD","BK4533","LU2357305700.SGD","BIIB","GB00BDT5M118.USD","LU0061475181.USD","LU0466842654.USD","LU2237443622.USD","SG9999018865.SGD","LU2106854487.HKD","LU0203201768.USD","LU1023059063.AUD","SG9999014880.SGD","LU0079474960.USD","LU2491050071.SGD","LU1868836591.USD","LU0289739699.SGD","PRTA","LU1983299246.USD","SG9999014914.USD","LU0198837287.USD","CSTL","EC","IE00BJT1NW94.SGD","LU0114720955.EUR","LU0456855351.SGD"],"gpt_icon":1},{"id":"2508248669","title":"Strong week for Castle Biosciences (NASDAQ:CSTL) shareholders doesn't alleviate pain of three-year loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2508248669","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508248669?lang=en_us&edition=fundamental","pubTime":"2025-02-01 20:17","pubTimestamp":1738412243,"startTime":"0","endTime":"0","summary":"Many investors define successful investing as beating the market average over the long term. But its virtually certain that sometimes you will buy stocks that fall short of the market average returns. Unfortunately, that's been the case for longer term Castle Biosciences, Inc.  shareholders, since the share price is down 34% in the last three years, falling well short of the market return of around 36%. Furthermore, it's down 15% in about a quarter. That's not much fun for holders.Although the past week has been more reassuring for shareholders, they're still in the red over the last three years, so let's see if the underlying business has been responsible for the decline.Given that Castle Biosciences only made minimal earnings in the last twelve months, we'll focus on revenue to gauge its business development. As a general rule, we think this kind of company is more comparable to loss-making stocks, since the actual profit is so low. For shareholders to have confidence a company will ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/strong-week-castle-biosciences-nasdaq-121723277.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BKPKM429.USD","LU2095319765.USD","IE00BGHQF748.EUR","NDAQ","USJW.SI","QID","USAW.SI","SQQQ","LU2210150020.SGD","BK4585","BK4588","QLD","IE00B64PRP62.GBP","CSTL","NVIW.SI","IE00B3QW5Z07.USD","BK4196","PSQ","LU2210149790.SGD","BK4112","TQQQ","NQmain","TSYW.SI","MNQmain",".IXIC"],"gpt_icon":1},{"id":"2508998150","title":"VRTX Gets FDA Nod for Non-Opioid Pain Drug Journavx, Shares Up","url":"https://stock-news.laohu8.com/highlight/detail?id=2508998150","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508998150?lang=en_us&edition=fundamental","pubTime":"2025-01-31 23:56","pubTimestamp":1738338960,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals Incorporated VRTX announced that the FDA has approved its oral, non-opioid, highly selective NaV1.8 pain signal inhibitor, suzetrigine, for the treatment of adults with moderate-to-severe acute pain. The pain drug will be marketed by the name of Journavx.Following the nod, Journavx has become the first and only non-opioid oral pain signal inhibitor and the first new class of pain medicine to be approved by the FDA in more than 20 years.Per the company, Journavx has the potential to transform the treatment paradigm of acute pain. Pain is an area with limited treatment options, mostly highly addictive opioid-based medications.Vertex believes Journavx, a non-opioid drug, is an effective and well-tolerated medicine for use in all types of moderate-to-severe acute pain.Shares of VRTX were up more than 8% in after-hours trading on Jan. 30 following the news announcement. The stock was also up in pre-market trading on Jan. 31.Besides acute pain, suzetrigine is also bein","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/vrtx-gets-fda-nod-non-155600022.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BFTCPJ56.SGD","BK4196","BMRN","CSTL","HRMY","VERX","BK4585","IE00B7SZLL34.SGD","BK4139","BK4007","LU0058720904.USD","LU1585245621.USD","LU2236285917.USD","LU2462157665.USD","LU0417517546.SGD","LU0256863811.USD","LU1093756168.USD","IE00B19Z9Z06.USD","LU0109394709.USD","LU1815336091.USD","LU0823416689.USD","LU2362541513.USD","BK4533","LU1430594728.SGD","IE0009355771.USD","VRTX","IE00B19Z9P08.USD","LU0889565916.HKD","BK4532","LU1559883803.SGD","BK4566","IE00BJT1NW94.SGD","LU0061475181.USD","LU0289739699.SGD","LU1093756325.SGD","LU0320765992.SGD","LU2237438978.USD","LU0757428866.USD","IE00B4R5TH58.HKD","LU1035775433.USD","LU2362540622.SGD","IE00B19Z3B42.SGD","LU2456880835.USD","LU0234570918.USD","BK4567","IE00B894F039.SGD","LU1069344957.HKD","LU2362541273.HKD","BK4023","BK4588"],"gpt_icon":0},{"id":"2508499339","title":"CMRX Stock Skyrockets in 3 Months: Here's What You Should Know","url":"https://stock-news.laohu8.com/highlight/detail?id=2508499339","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508499339?lang=en_us&edition=fundamental","pubTime":"2025-01-31 23:43","pubTimestamp":1738338180,"startTime":"0","endTime":"0","summary":"Shares of Chimerix CMRX have skyrocketed 323.7% in the past three months following the company’s submission of a new drug application  to the FDA, seeking accelerated approval for its lead candidate, dordaviprone, to treat patients with recurrent H3 K27M-mutant diffuse glioma. CMRX’s dordaviprone is a first-in-class small molecule imipridone with a novel mechanism of action.Chimerix has also requested the FDA to grant the Priority Review status to the dordaviprone NDA filing for the glioma indication. A filing accepted under the regulatory body’s Priority Review pathway reduces the review period to six months from the standard 10 months. This status is given to treatments that the FDA believes, could significantly improve existing options or provide solutions where no approved therapy exists. Subject to a grant from the FDA, a final decision is expected in the third quarter of 2025.Please note that CMRX’s dordaviprone already enjoys the Rare Pediatric Disease Designation for H3 K27M-mu","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cmrx-stock-skyrockets-3-months-154300643.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4566","BMRN","BK4585","BK4583","IE00B19Z3581.USD","BK4139","CSTL","IE00B19Z3B42.SGD","BK4548","IE0002270589.USD","CMRX","ALNY","IE00B7SZLL34.SGD","BK4196","BK4588"],"gpt_icon":0},{"id":"2507487654","title":"FDA Clears Allogene's IND for CAR T Therapy in Autoimmune Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2507487654","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507487654?lang=en_us&edition=fundamental","pubTime":"2025-01-30 00:34","pubTimestamp":1738168440,"startTime":"0","endTime":"0","summary":"Allogene Therapeutics, Inc. ALLO announced that the FDA has cleared its investigational new drug  application to begin clinical studies on its investigational CRISPR-based allogenic CAR-T therapy, ALLO-329, for the treatment of various autoimmune diseases.The phase I RESOLUTION basket study will evaluate the safety and preliminary efficacy of ALLO-329 in patients with systemic lupus erythematosus, including lupus nephritis, idiopathic inflammatory myopathies and systemic sclerosis.The study, which aims to offer a key understanding of ALLO-329's potential to transform the treatment paradigm across a range of autoimmune diseases, is expected to begin in mid-2025. The company expects to have proof-of-concept from the basket study by the end of 2025.A next-generation allogeneic CAR T-cell therapy, ALLO-329, works by targeting both CD19+ B-cells and CD70+ activated T-cells. Additionally, the candidate incorporates ALLO’s proprietary Dagger technology, which is designed to reduce or 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