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Lyell Immunopharma, Inc.

22.39

-1.4600-6.12%

Post-market: 22.390.00000.00%16:10 EDT

Volume:108.47K

Turnover:2.51M

Market Cap:521.85M

PE:-1.39

High:24.23

Open:24.00

Low:22.37

Close:23.85

52wk High:45.00

52wk Low:7.65

Shares:23.31M

Float Shares:14.16M

Volume Ratio:1.22

T/O Rate:0.77%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-16.0600

EPS(LYR):-26.2348

ROE:-86.98%

ROA:-29.83%

PB:2.10

PE(LYR):-0.85

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Overview Company News Filings

NASDAQ TRADE HALT VOLATILITY TRADING PAUSE AT 12:04 PM

Lyell Immunopharma Shares Rise After HC Wainwright Upgrade

MT Newswires Live

BUZZ-H.C. Wainwright upgrades Lyell to 'buy' on cell therapy progression

Lyell Immunopharma Raised to Buy From Neutral by HC Wainwright & Co.

HC Wainwright Upgrades Lyell Immunopharma to Buy From Neutral, Adjusts PT to $45 From $20

MT Newswires Live

Lyell Immunopharma Inc : H.c. Wainwright Raises to Buy From Neutral; Raises Target Price to $45 From $20

THOMSON REUTERS

Lyell Immunopharma Reports High Response Rates for Ronde-Cel in Large B-Cell Lymphoma Trial

Lyell Immunopharma Presents New Clinical Data From Ongoing Trial of Ronde-Cel Showing High Rates of Durable Complete Responses in Patients With Large B-Cell Lymphoma at the 67TH Ash Annual Meeting and Exposition

THOMSON REUTERS

Lyell Immunopharma Files for Proposed Resale From Time to Time by Innovative Cellular Therapeutics Holdings Limited of up to 1.9 Mln Shares

THOMSON REUTERS

Lyell Immunopharma Updates Bylaws on Stockholder Proposals and Voting Standards

Lyell Immunopharma Is Maintained at Neutral by HC Wainwright & Co.

Lyell Immunopharma, Inc.'s (NASDAQ:LYEL) one-year returns climbed after last week's 13% gain, institutional investors must be happy

Simply Wall St.

Lyell Immunopharma Q3 Sales $15.000K Down From $34.000K YoY

Lyell Immunopharma Q3 adjusted net loss beats estimates

Lyell Immunopharma reports Q3 revenue $15k vs $34k last year

Lyell Immunopharma Launches Phase 3 Head-to-Head CAR T-Cell Therapy Trial in Large B-Cell Lymphoma

Press Release: Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2025

Lyell Immunopharma Files Initial Beneficial Ownership Statement for VP, Corporate Controller Veronica Sanchez Bulis

Lyell Immunopharma Acquires Global Rights to Next-Generation CAR T-Cell Therapy for Colorectal Cancer

Lyell Immunopharma Inc - Ict to Receive $40 Mln and 1.9 Mln Lyell Shares

THOMSON REUTERS

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rose 2.6% in recent Tuesday trading after HC Wainwright upgraded the stock to buy from neutral and raised its price target to $45 from $20.Trading volume stood at over 61,000 shares compared with a daily average of about 46,000.Price: 29.11, Change: +0.75, Percent Change: +2.64","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2590347763","title":"BUZZ-H.C. Wainwright upgrades Lyell to 'buy' on cell therapy progression","url":"https://stock-news.laohu8.com/highlight/detail?id=2590347763","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590347763?lang=en_us&edition=fundamental","pubTime":"2025-12-09 23:18","pubTimestamp":1765293481,"startTime":"0","endTime":"0","summary":"BUZZ-H.C. Wainwright upgrades Lyell to 'buy' on cell therapy progression** Brokerage H.C. Wainwright upgrades cancer therapy developer Lyell Immunopharma's LYEL.O rating to \"buy\" from \"neutral\"; raises PT to $45 from $20** New PT represents a 45.3% upside to the stock's Monday close** Brokerage says Lyell's Ronde-cel \"has established itself as the durability leader\" among rival cell therapies for large B-cell lymphoma, an aggressive type of blood cancer** Ronde-cel is the only therapy to report an 18-month median progression-free survival, a key measure of how long patients live without their disease worsening, H.C. Wainwright notes ** Brokerage also sees big potential in Lyell's LYL273 therapy for colorectal cancer, saying its 25-month survival data more than doubles the benchmark and its 67% response rate far surpasses current standard-of-care options that offer \"response rates below 6%\"** Market is \"severely underestimating\" LYL273's chance to become a standard-of-care option in a m","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nL6N3XF0PP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","LYEL","BK4139","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2590134822","title":"Lyell Immunopharma Raised to Buy From Neutral by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2590134822","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590134822?lang=en_us&edition=fundamental","pubTime":"2025-12-09 19:39","pubTimestamp":1765280340,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/LYEL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 09, 2025 06:39 ET (11:39 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2590634855","title":"HC Wainwright Upgrades Lyell Immunopharma to Buy From Neutral, Adjusts PT to $45 From $20","url":"https://stock-news.laohu8.com/highlight/detail?id=2590634855","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590634855?lang=en_us&edition=fundamental","pubTime":"2025-12-09 19:25","pubTimestamp":1765279516,"startTime":"0","endTime":"0","summary":"HC Wainwright Upgrades Lyell Immunopharma to Buy From Neutral, Adjusts PT to $45 From $20","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PT","LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2590100653","title":"Lyell Immunopharma Inc : H.c. Wainwright Raises to Buy From Neutral; Raises Target Price to $45 From $20","url":"https://stock-news.laohu8.com/highlight/detail?id=2590100653","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590100653?lang=en_us&edition=fundamental","pubTime":"2025-12-09 19:16","pubTimestamp":1765278968,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nFWN3XF092:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4505","BK4539","LYEL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2589806988","title":"Lyell Immunopharma Reports High Response Rates for Ronde-Cel in Large B-Cell Lymphoma Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2589806988","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589806988?lang=en_us&edition=fundamental","pubTime":"2025-12-08 05:30","pubTimestamp":1765143014,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Inc. has announced new clinical and translational data from its ongoing trial of rondecabtagene autoleucel  in patients with large B-cell lymphoma. The results were presented at the 67th American Society of Hematology  Annual Meeting and Exposition. As of the September 5, 2025, data cutoff, ronde-cel demonstrated a 93% overall response rate and a 76% complete response rate in the third- or later-line setting, with a median progression-free survival of 18 months. In the second-line setting, patients achieved an 83% overall response rate and a 61% complete response rate. The safety profile was reported as manageable, with no high-grade cytokine release syndrome and 5% or fewer patients experiencing Grade 3 or higher ICANS following dexamethasone prophylaxis. Presentation materials and a webcast replay will be available on the Lyell website.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to pro","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251207:nNDL98NtBk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3QW5Z07.USD","SG9999014013.SGD","LU2095319765.USD","LYEL","BK4585","LU2210149790.SGD","SG9999014005.SGD","BK4112","BK4505","BK4588","NDAQ","BK4539","IE00BGHQF748.EUR","BK4139","LU2210150020.SGD","IE00B64PRP62.GBP","SG9999014021.USD","IE00BKPKM429.USD","LU0314104364.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2589806984","title":"Lyell Immunopharma Presents New Clinical Data From Ongoing Trial of Ronde-Cel Showing High Rates of Durable Complete Responses in Patients With Large B-Cell Lymphoma at the 67TH Ash Annual Meeting and Exposition","url":"https://stock-news.laohu8.com/highlight/detail?id=2589806984","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589806984?lang=en_us&edition=fundamental","pubTime":"2025-12-08 05:30","pubTimestamp":1765143000,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251207:nTUAB7YHSR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4539","BK4139","LYEL","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2589481048","title":"Lyell Immunopharma Files for Proposed Resale From Time to Time by Innovative Cellular Therapeutics Holdings Limited of up to 1.9 Mln Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2589481048","media":"THOMSON REUTERS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589481048?lang=en_us&edition=fundamental","pubTime":"2025-12-06 05:39","pubTimestamp":1764970768,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251205:nFWN3XB0IP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LYEL","BK4505","BK4539","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2589749817","title":"Lyell Immunopharma Updates Bylaws on Stockholder Proposals and Voting Standards","url":"https://stock-news.laohu8.com/highlight/detail?id=2589749817","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589749817?lang=en_us&edition=fundamental","pubTime":"2025-12-06 05:05","pubTimestamp":1764968755,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Inc. has amended and restated its bylaws, introducing changes to modernize stockholder proposal procedures and disclosure requirements, clarify rules for updating previously submitted proposals, conform notice provisions to Delaware law, simplify voting standards for director elections and proposals, and align stockholder list requirements with Delaware regulations. The amendments are effective immediately.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Lyell Immunopharma Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 05, 2025, and is solely responsible f","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251205:nNDL7SDMqF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","LYEL","BK4139","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2585462942","title":"Lyell Immunopharma Is Maintained at Neutral by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2585462942","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2585462942?lang=en_us&edition=fundamental","pubTime":"2025-11-24 21:02","pubTimestamp":1763989320,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/LYEL/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 24, 2025 08:02 ET (13:02 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2585172490","title":"Lyell Immunopharma, Inc.'s (NASDAQ:LYEL) one-year returns climbed after last week's 13% gain, institutional investors must be happy","url":"https://stock-news.laohu8.com/highlight/detail?id=2585172490","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2585172490?lang=en_us&edition=fundamental","pubTime":"2025-11-22 20:19","pubTimestamp":1763813950,"startTime":"0","endTime":"0","summary":"Key Insights Significantly high institutional ownership implies Lyell Immunopharma's stock price is sensitive to their...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-lyel/lyell-immunopharma/news/lyell-immunopharma-incs-nasdaqlyel-one-year-returns-climbed","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-lyel/lyell-immunopharma/news/lyell-immunopharma-incs-nasdaqlyel-one-year-returns-climbed","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","BK4505","QID",".IXIC","USJW.SI","MNQmain","BK4539","NQmain","LYEL","QLD","PSQ","NVIW.SI","SQQQ","USAW.SI","TQQQ","TSYW.SI"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2583658524","title":"Lyell Immunopharma Q3 Sales $15.000K Down From $34.000K YoY","url":"https://stock-news.laohu8.com/highlight/detail?id=2583658524","media":"Benzinga","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583658524?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:47","pubTimestamp":1762984068,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Q3 Sales $15.000K Down From $34.000K YoY","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/25/11/48820751/lyell-immunopharma-q3-sales-15-000k-down-from-34-000k-yoy","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Lyell Immunopharma Q3 Sales $15.000K Down From $34.000K YoY","news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2583858905","title":"Lyell Immunopharma Q3 adjusted net loss beats estimates","url":"https://stock-news.laohu8.com/highlight/detail?id=2583858905","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583858905?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:33","pubTimestamp":1762983230,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Q3 adjusted net loss beats estimatesOverviewLyell Q3 adjusted net loss beats analyst expectationsCompany acquired global rights to LYL273, a GCC-targeted CAR T-cell productInitiated","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251112:nL1N3WO13Y:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LYEL","BK4505","BK4139","BK4539"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2583585188","title":"Lyell Immunopharma reports Q3 revenue $15k vs $34k last year","url":"https://stock-news.laohu8.com/highlight/detail?id=2583585188","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583585188?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:32","pubTimestamp":1762983137,"startTime":"0","endTime":"0","summary":"“Lyell is well positioned with two next-generation CAR T-cell product candidates, each with promising clinical data. We look forward to effectively...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/lyell-immunopharma-reports-q3-revenue-15k-vs-34k-last-year-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/lyell-immunopharma-reports-q3-revenue-15k-vs-34k-last-year-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2583588391","title":"Lyell Immunopharma Launches Phase 3 Head-to-Head CAR T-Cell Therapy Trial in Large B-Cell Lymphoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2583588391","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583588391?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:05","pubTimestamp":1762981539,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Inc. announced updates on its next-generation CAR T-cell therapy programs, including new developments in its clinical pipeline. The company reported that it will present new clinical and translational data from its Phase 1/2 clinical trial of ronde-cel for the treatment of aggressive large B-cell lymphoma at the upcoming ASH 67th Annual Meeting and Exposition in December. Additionally, Lyell has initiated the PiNACLE - H2H, a Phase 3 head-to-head CAR T-cell therapy clinical trial in the second-line  setting for aggressive large B-cell lymphoma, with enrollment expected to begin by early 2026. The company also acquired exclusive global rights to LYL273, a novel GCC-targeted CAR T-cell product candidate, which has shown a 67% overall response rate and an 83% disease control rate with a manageable safety profile in an ongoing U.S. Phase 1 clinical trial in patients with refractory metastatic colorectal cancer. The next data update from this trial is anticipated in the f","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251112:nNDL55qMWt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","LU2210150020.SGD","BK4588","NDAQ","BK4539","BK4139","LU2210149790.SGD","LU2095319765.USD","IE00B64PRP62.GBP","IE00BKPKM429.USD","LU0314104364.USD","BK4112","BK4585","LYEL","IE00B3QW5Z07.USD","IE00BGHQF748.EUR"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2583588639","title":"Press Release: Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2583588639","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583588639?lang=en_us&edition=fundamental","pubTime":"2025-11-13 05:05","pubTimestamp":1762981500,"startTime":"0","endTime":"0","summary":"-- Acquired exclusive global rights to LYL273, a novel GCC-targeted CAR. T-cell product candidate that has demonstrated a 67% overall response. rate, an 83% disease control rate and a manageable safety profile at the. highest dose level studied to date in patients with refractory metastatic. colorectal cancer in an ongoing U.S. Phase 1 clinical trial. -- Received RMAT designation from the U.S. FDA for ronde-cel for the. treatment of patients with relapsed or refractory LBCL receiving. data from the Phase 1/2 clinical trial of ronde--cel for the treatment of. -- Announced the initiation of PiNACLE - H2H, a Phase 3 head-to-head CAR. SOUTH SAN FRANCISCO, Calif., Nov. 12, 2025  -- Lyell Immunopharma, Inc. , a late-stage clinical company advancing next-generation chimeric antigen receptor  T-cell therapies for patients with cancer, today reported financial results and business highlights for the third quarter ended September 30, 2025.Lyell recently acquired exclusive global rights  to LYL27","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LYEL","GCC","ORR","BK4505","BK4230","CAR","BK4022","BK4139","BK4539"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2582338578","title":"Lyell Immunopharma Files Initial Beneficial Ownership Statement for VP, Corporate Controller Veronica Sanchez Bulis","url":"https://stock-news.laohu8.com/highlight/detail?id=2582338578","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582338578?lang=en_us&edition=fundamental","pubTime":"2025-11-11 10:08","pubTimestamp":1762826911,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma Inc. has filed an initial statement of beneficial ownership with the U.S. Securities and Exchange Commission. The filing names Veronica Sanchez Bulis, who serves as Vice President, Corporate Controller, as the beneficial owner. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Lyell Immunopharma Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on November 10, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251111:nNDL75kr9W:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","BK4139","BK4539","LYEL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2582875777","title":"Lyell Immunopharma Acquires Global Rights to Next-Generation CAR T-Cell Therapy for Colorectal Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2582875777","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582875777?lang=en_us&edition=fundamental","pubTime":"2025-11-10 20:30","pubTimestamp":1762777830,"startTime":"0","endTime":"0","summary":"Lyell Immunopharma has acquired exclusive global rights, outside of mainland China, Hong Kong, Macau, and Taiwan, to LYL273, a next-generation CAR T-cell product candidate targeting metastatic colorectal cancer. LYL273, which is currently in a U.S. Phase 1 clinical trial, has shown a 67% overall response rate and an 83% disease control rate at its highest dose, along with a manageable safety profile in patients with refractory metastatic colorectal cancer. Under the agreement, Lyell will make a $40 million upfront payment and issue 1.9 million shares of its common stock to ICT, the original developer. ICT is also eligible for additional milestone payments, further equity, and tiered royalties on future sales. Lyell expects the transaction to have a modest impact on 2025 operating expenses and projects cash reserves to fund operations into 2027.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL9xF0Sj:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IE00B64PRP62.GBP","IE00BGHQF748.EUR","LU2210149790.SGD","LU0314104364.USD","LU2210150020.SGD","LYEL","BK4539","BK4588","IE00BKPKM429.USD","NDAQ","BK4585","BK4112","LU2095319765.USD","BK4505","IE00B3QW5Z07.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2582876882","title":"Lyell Immunopharma Inc - Ict to Receive $40 Mln and 1.9 Mln Lyell Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2582876882","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582876882?lang=en_us&edition=fundamental","pubTime":"2025-11-10 20:30","pubTimestamp":1762777800,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nTUA3CSC9F:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4539","LYEL","BK4505","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":2,"totalSize":49,"code":"91000000","status":"200"}]}}