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PTC Therapeutics

44.23

+1.724.05%

Post-market: 44.400.1700+0.38%18:23 EDT

Volume:1.54M

Turnover:68.48M

Market Cap:3.51B

PE:5.89

High:46.03

Open:44.29

Low:43.95

Close:42.51

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Overview Company News Filings

PTC Therapeutics Inc - Novartis to Assume Global Development and Commercial Responsibilities

THOMSON REUTERS

PTC Therapeutics to sell Priority Review Voucher for $150M

RBC Capital Remains a Hold on PTC Therapeutics (PTCT)

BUZZ-PTC Therapeutics falls after scrapping development of ALS drug

PTC Therapeutics Ends Utreloxastat Development After Rare Neurodegenerative Disease Trial Misses Goal, Analyst Maintains Outperform With Focus On Sepiapterin, Huntington's Programs

TD Cowen Remains a Hold on PTC Therapeutics (PTCT)

PTC Therapeutics Sells Priority Review Voucher for $150M

PTC Therapeutics to Sell Rare Pediatric Disease Voucher for $150 Million

MT Newswires Live

PTC Therapeutics price target raised to $52 from $48 at Baird

BRIEF-PTC Therapeutics Enters Into Agreement To Sell Priority Review Voucher For $150 Mln

PTC Therapeutics Inc - to Sell Priority Review Voucher for $150 Million

THOMSON REUTERS

PTC Therapeutics: Sell Rating Due to Unmet Trial Goals and Overvaluation Concerns

PTC Therapeutics: Growth Potential Amid Strategic Shifts and Upcoming Catalysts

BRIEF-Ptc Therapeutics Announces Topline Results Of Cardinals Trial Of Utreloxastat In ALS Patients

PTC Therapeutics' Amyotrophic Lateral Sclerosis Trial Fails to Meet Endpoints; Shares Fall After Hours

MT Newswires Live

PTC Therapeutics to End Development of ALS Treatment

UPDATE 1-PTC Therapeutics discontinues development of ALS drug after trial failure

PTC Therapeutics' ALS drug fails mid-stage trial

PTC Therapeutics: Phase 2 CardinALS study did not meet its primary endpoint

PTC Therapeutics Inc - Study Failed to Meet Primary and Secondary Efficacy Endpoints

THOMSON REUTERS

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PTC was granted the PRV on November 13 along with the U.S. FDA approval of KEBILIDI for the treatment of children and adults with AADC deficiency, including the full spectrum of disease severity. The transaction is subject to customary closing conditions, including expiration of the applicable waiting period under the Hart-Scott Rodino Antitrust Improvements Act.Unlock your investing potential with TipRanks Premium - Now At 40% OFF!Make smarter investments with weekly expert stock picks from the Smart Investor Newsletter. PTC Therapeutics: Phase 2 CardinALS study did not meet its primary endpoint. PTC Therapeutics price target raised to $62 from $51 at JPMorgan. PTC Therapeutics price target raised to $45 from $43 at Barclays. PTC Therapeutics’ AADC deficiency gene therapy granted FDA approval. 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PTCT   ** \"While this outcome is unfortunate, expectations were low given that drug development in ALS has been difficult and supporting evidence for utreloxastat in ALS was limited\" - TD Cowen analysts** ALS is a rare neurological disease that can break down nerve cells, in the brain and spinal cord, responsible for muscle movements** Including session moves, stock up about 64% YTD   ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nL3N3MY0U9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0109394709.USD","LU0320765992.SGD","PTCT","LU0889565916.HKD","BK4139"],"gpt_icon":0},{"id":"2486822810","title":"PTC Therapeutics Ends Utreloxastat Development After Rare Neurodegenerative Disease Trial Misses Goal, Analyst Maintains Outperform With Focus On Sepiapterin, Huntington's Programs","url":"https://stock-news.laohu8.com/highlight/detail?id=2486822810","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486822810?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:51","pubTimestamp":1732711909,"startTime":"0","endTime":"0","summary":"On Tuesday, PTC Therapeutics Inc  revealed data from the global Phase 2 placebo-controlled CardinALS study of Utreloxastat in amyotrophic lateral sclerosis patients.The study did not meet its primary endpoint of slowing disease progression on the composite ALSFRS-R and mortality analysis.Also Read: FDA Grants Conditional Approval For PTC Therapeutics’ Gene Therapy As First Ever With Direct Administration In Brain. While modest numerical benefit was recorded on the primary endpoint, and a favorable clinical effect was correlated with lowering plasma neurofilament light chain , a biomarker of neuronal damage, statistical significance was not achieved . In addition, significance was not achieved on the secondary efficacy endpoints.Amyotrophic lateral sclerosis , sometimes referred to as motor neuron disease orLou Gehrig’sdisease, is a rare neurodegenerative disease that affects motor neurons in the brain and spinal cord.William Blair notes that while the CardinALS trial results were disap","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/FnJ.mFfpCKSrtOcSH4laOw--~B/aD01NzQ7dz0xMDIwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/82f86e39bff97a0491140bfd0b706ed3","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/FnJ.mFfpCKSrtOcSH4laOw--~B/aD01NzQ7dz0xMDIwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/82f86e39bff97a0491140bfd0b706ed3"],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ptc-therapeutics-ends-utreloxastat-development-125149426.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PTC","PTCT"],"gpt_icon":0},{"id":"2486825771","title":"TD Cowen Remains a Hold on PTC Therapeutics (PTCT)","url":"https://stock-news.laohu8.com/highlight/detail?id=2486825771","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486825771?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:35","pubTimestamp":1732710940,"startTime":"0","endTime":"0","summary":"In a report released today, Joseph Thome from TD Cowen maintained a Hold rating on PTC Therapeutics (PTCT – Research Report), with a price target o...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/td-cowen-remains-a-hold-on-ptc-therapeutics-ptct?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/td-cowen-remains-a-hold-on-ptc-therapeutics-ptct?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0320765992.SGD","LU1721428347.USD","BK4127","BK4554","LU2362541273.HKD","BK4207","LU2362540622.SGD","LU2506952337.HKD","LU2506952410.USD","LU2477742899.HKD","LU2362541513.USD","BK4139","BK4585","BK4566","LU1951200564.SGD","LU1951198990.SGD","PTCT","COWN","TD","LU0889565916.HKD","BK4023","LU0109394709.USD","PTC","LU1923623000.USD","BK4588","BK4576"],"gpt_icon":0},{"id":"2486449825","title":"PTC Therapeutics Sells Priority Review Voucher for $150M","url":"https://stock-news.laohu8.com/highlight/detail?id=2486449825","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486449825?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:32","pubTimestamp":1732710749,"startTime":"0","endTime":"0","summary":"PTC Therapeutics ( ($PTCT) ) just unveiled an update. PTC Therapeutics has struck a $150 million deal to sell its Rare Pediatric Disease Priority R...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/ptc-therapeutics-sells-priority-review-voucher-for-150m?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/ptc-therapeutics-sells-priority-review-voucher-for-150m?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU2506952337.HKD","LU2477742899.HKD","LU0320765992.SGD","LU2506952410.USD","LU1721428347.USD","LU0109394709.USD","BK4554","LU2362541273.HKD","BK4023","LU1951200564.SGD","BK4588","PTC","LU2362540622.SGD","BK4576","LU1923623000.USD","LU0889565916.HKD","BK4139","LU1951198990.SGD","LU2362541513.USD","BK4585","PTCT"],"gpt_icon":0},{"id":"2486823039","title":"PTC Therapeutics to Sell Rare Pediatric Disease Voucher for $150 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2486823039","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486823039?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:26","pubTimestamp":1732710415,"startTime":"0","endTime":"0","summary":"PTC Therapeutics (PTCT) said Wednesday it agreed to sell its Rare Pediatric Disease Priority Review Voucher for $150 million, upon completion of the transaction.The voucher was granted on Nov. 13 alon","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","LU1923623000.USD","LU2506952410.USD","LU2362540622.SGD","LU0109394709.USD","BK4576","LU2362541273.HKD","BK4588","LU0320765992.SGD","BK4554","LU2362541513.USD","BK4023","BK4585","PTCT","LU1721428347.USD","LU2477742899.HKD","LU0889565916.HKD","LU1951198990.SGD","LU2506952337.HKD","LU1951200564.SGD","PTC"],"gpt_icon":0},{"id":"2486825711","title":"PTC Therapeutics price target raised to $52 from $48 at Baird","url":"https://stock-news.laohu8.com/highlight/detail?id=2486825711","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486825711?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:25","pubTimestamp":1732710347,"startTime":"0","endTime":"0","summary":"Baird analyst Joel Beatty raised the firm’s price target on PTC Therapeutics (PTCT) to $52 from $48 and keeps an Outperform rating on the shares. T...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ptc-therapeutics-price-target-raised-to-52-from-48-at-baird?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ptc-therapeutics-price-target-raised-to-52-from-48-at-baird?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PTC","PTCT"],"gpt_icon":0},{"id":"2486289848","title":"BRIEF-PTC Therapeutics Enters Into Agreement To Sell Priority Review Voucher For $150 Mln","url":"https://stock-news.laohu8.com/highlight/detail?id=2486289848","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486289848?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:01","pubTimestamp":1732708901,"startTime":"0","endTime":"0","summary":"Nov 27 (Reuters) - PTC Therapeutics Inc   :   * PTC THERAPEUTICS ENTERS INTO AGREEMENT TO SELL PRIORITY REVIEW VOUCHER FOR $150 MILLION   * PTC THERAPEUTICS INC - TO SELL PRIORITY REVIEW VOUCHER FOR $150 MILLIONSource text:    Further company coverage:    ((Reuters.Briefs@thomsonreuters.com;))","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LU1951200564.SGD","LU2362541513.USD","PTC","BK4139","LU1721428347.USD","LU1923623000.USD","LU2506952410.USD","LU2362540622.SGD","BK4023","LU2506952337.HKD","PTCT","BK4576","LU0109394709.USD","LU1951198990.SGD","LU0889565916.HKD","BK4554","LU0320765992.SGD","LU2477742899.HKD","LU2362541273.HKD","BK4588"],"gpt_icon":0},{"id":"2486009840","title":"PTC Therapeutics Inc - to Sell Priority Review Voucher for $150 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2486009840","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486009840?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:00","pubTimestamp":1732708804,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA7GVQJJ:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0109394709.USD","PTCT","BK4139","LU0320765992.SGD","LU0889565916.HKD"],"gpt_icon":0},{"id":"2486841946","title":"PTC Therapeutics: Sell Rating Due to Unmet Trial Goals and Overvaluation Concerns","url":"https://stock-news.laohu8.com/highlight/detail?id=2486841946","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486841946?lang=en_us&edition=fundamental","pubTime":"2024-11-27 18:35","pubTimestamp":1732703752,"startTime":"0","endTime":"0","summary":"Bank of America Securities analyst Tazeen Ahmad maintained a Sell rating on PTC Therapeutics (PTCT – Research Report) yesterday and set a price tar...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ptc-therapeutics-sell-rating-due-to-unmet-trial-goals-and-overvaluation-concerns?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ptc-therapeutics-sell-rating-due-to-unmet-trial-goals-and-overvaluation-concerns?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PTC","PTCT"],"gpt_icon":0},{"id":"2486210855","title":"PTC Therapeutics: Growth Potential Amid Strategic Shifts and Upcoming Catalysts","url":"https://stock-news.laohu8.com/highlight/detail?id=2486210855","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486210855?lang=en_us&edition=fundamental","pubTime":"2024-11-27 06:55","pubTimestamp":1732661710,"startTime":"0","endTime":"0","summary":"William Blair analyst Sami Corwin has maintained their bullish stance on PTCT stock, giving a Buy rating today. Sami Corwin’s rating is based on se...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/ptc-therapeutics-growth-potential-amid-strategic-shifts-and-upcoming-catalysts?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/ptc-therapeutics-growth-potential-amid-strategic-shifts-and-upcoming-catalysts?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU2477742899.HKD","BK4139","LU2506952337.HKD","LU2362540622.SGD","LU2506952410.USD","LU0109394709.USD","BK4023","LU1951200564.SGD","PTC","LU2362541513.USD","LU1721428347.USD","BK4554","BK4588","BK4585","LU0889565916.HKD","BK4576","LU1923623000.USD","PTCT","LU2362541273.HKD","LU1951198990.SGD","LU0320765992.SGD"],"gpt_icon":0},{"id":"2486853231","title":"BRIEF-Ptc Therapeutics Announces Topline Results Of Cardinals Trial Of Utreloxastat In ALS Patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2486853231","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486853231?lang=en_us&edition=fundamental","pubTime":"2024-11-27 06:41","pubTimestamp":1732660873,"startTime":"0","endTime":"0","summary":"Nov 26  - PTC Therapeutics Inc   :   * PTC THERAPEUTICS ANNOUNCES TOPLINE RESULTS OF CARDINALS TRIAL OF UTRELOXASTAT IN ALS PATIENTS   * PTC THERAPEUTICS INC - STUDY FAILED TO MEET PRIMARY AND SECONDARY EFFICACY ENDPOINTS   * PTC THERAPEUTICS INC - UTRELOXASTAT WAS DEMONSTRATED TO BE SAFE AND WELL TOLERATED IN CARDINALS TRIAL   * PTC THERAPEUTICS INC - FURTHER DEVELOPMENT OF UTRELOXASTAT NOT PLANNEDSource text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PTCT","LENZ","BK4139","LU0889565916.HKD","LU0109394709.USD","LU0320765992.SGD"],"gpt_icon":0},{"id":"2486858154","title":"PTC Therapeutics' Amyotrophic Lateral Sclerosis Trial Fails to Meet Endpoints; Shares Fall After Hours","url":"https://stock-news.laohu8.com/highlight/detail?id=2486858154","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486858154?lang=en_us&edition=fundamental","pubTime":"2024-11-27 06:23","pubTimestamp":1732659790,"startTime":"0","endTime":"0","summary":"PTC Therapeutics  said late Tuesday that a global phase 2 trial of Utreloxastat in patients with amyotrophic lateral sclerosis failed to meet its primary and secondary efficacy endpoints.The study didn't meet its primary endpoint of slowing disease progression on the composite ALSFRS-R and mortality analysis, while significance wasn't achieved on the secondary efficacy endpoints, the company said.Although Utreloxastat was safe and well tolerated in the trial, further development is currently not planned due to the lack of efficacy and biomarker signal, PTC said.Amyotrophic lateral sclerosis is a rare and fatal neurodegenerative disease that affects motor neurons in the brain and spinal cord.The company's shares were down 5.5% in after-hours activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PTC","LU1923623000.USD","LU2506952337.HKD","LU2506952410.USD","LU2477742899.HKD","LU1951200564.SGD","BK4585","LU2362541513.USD","BK4023","PTCT","LU1721428347.USD","BK4554","LU0109394709.USD","BK4576","BK4139","LU0889565916.HKD","LU1951198990.SGD","LU2362540622.SGD","BK4588","LU0320765992.SGD","LU2362541273.HKD"],"gpt_icon":0},{"id":"2486830143","title":"PTC Therapeutics to End Development of ALS Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2486830143","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486830143?lang=en_us&edition=fundamental","pubTime":"2024-11-27 06:06","pubTimestamp":1732658760,"startTime":"0","endTime":"0","summary":"PTC Therapeutics will scrap development of its treatment for amyotrophic lateral sclerosis after it failed to meet a primary endpoint in a Phase 2 trial.The Warren, N.J., biopharmaceutical company said Tuesday that the treatment, called utreloxastat, didn't meet the goal of slowing disease progression, despite having demonstrated to be safe and well tolerated.\"We are of course disappointed that we were not able to demonstrate treatment efficacy and provide a potential therapy that could address the significant unmet medical need of ALS patients,\" Chief Executive Matthew Klein said.Shares fell 2.7%, to $44.75, in post-market trading after ending the regular session 7% higher, at $46.01.ALS, sometimes referred to as Lou Gehrig's disease, is a rare, progressive and fatal neurodegenerative disease that affects motor neurons in the brain and spinal cord.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4023","PTC","LU1923623000.USD","LU1951200564.SGD","BK4588","LU0320765992.SGD","LU1721428347.USD","LU1951198990.SGD","LU2506952410.USD","LU2362541273.HKD","BK4585","LU2506952337.HKD","BK4576","LU2362540622.SGD","LU0889565916.HKD","LU2362541513.USD","BK4139","PTCT","BK4554","LU2477742899.HKD","LU0109394709.USD"],"gpt_icon":0},{"id":"2486837400","title":"UPDATE 1-PTC Therapeutics discontinues development of ALS drug after trial failure","url":"https://stock-news.laohu8.com/highlight/detail?id=2486837400","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486837400?lang=en_us&edition=fundamental","pubTime":"2024-11-27 05:53","pubTimestamp":1732658006,"startTime":"0","endTime":"0","summary":"(Adds trial details in paragraph 2, background in paragraph 3 and share move in paragraph 4)      Nov 26 (Reuters) - PTC Therapeutics    said on Tuesday it is discontinuing the development of its 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trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2486324808","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486324808?lang=en_us&edition=fundamental","pubTime":"2024-11-27 05:37","pubTimestamp":1732657028,"startTime":"0","endTime":"0","summary":"PTC Therapeutics' ALS drug fails mid-stage trialNov 26  - PTC Therapeutics PTCT.O said on Tuesday its drug did not meet the main goal in a mid-stage trial evaluating it in patients with a type of fatal neurodegenerative disease called amyotrophic lateral sclerosis.  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(PTCT) announced that the global Phase 2 placebo-controlled CardinALS study did not meet its primary endpoint of slowing disease 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