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PTC Therapeutics

40.76

+4.5712.63%

Post-market: 40.00-0.7600-1.86%19:12 EDT

Volume:3.23M

Turnover:129.69M

Market Cap:3.21B

PE:-8.62

High:40.92

Open:39.40

Low:37.94

Close:36.19

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Overview Company News Filings

PTC Therapeutics Inc : Jefferies Raises Target Price to $62 From $55

THOMSON REUTERS

Sector Update: Health Care Stocks Slipping Late Afternoon

MT Newswires Live

Sector Update: Health Care Stocks Softer Monday Afternoon

MT Newswires Live

PTC Therapeutics Inks Licensing Pact With Novartis Worth Up To ~$3 Billion For Huntington's Program

PTC Therapeutics Strikes Up to $2.9 Billion Licensing Deal With Novartis for Huntington's Disease Drug Candidate

PTC Therapeutics Shares up 15.4% After Co Signs up to $2.9 Billion Licensing Deal With Novartis

THOMSON REUTERS

Sector Update: Health Care Stocks Mixed Pre-Bell Monday

MT Newswires Live

BUZZ-PTC Therapeutics rises on signing up to $2.9 billion licensing deal with Novartis

PTC Therapeutics Signs Exclusive Global License Deal With Novartis Unit for PTC518 Huntington's Disease Program; Shares Rise Premarket

MT Newswires Live

PTC Therapeutics signs up to $1.9 billion licensing deal with Novartis

BRIEF-PTC Therapeutics Enters Into A Global License And Collaboration Agreement With Novartis For PTC518 Huntington's Disease Program

PTC Therapeutics Shares Jump 14.1% Premarket After Agreement With Novartis for Huntington's Disease Program

THOMSON REUTERS

PTC Therapeutics Inc - to Receive $1 Billion in Cash at Closing

THOMSON REUTERS

PTC Therapeutics Enters Into a Global License and Collaboration Agreement With Novartis for PTC518 Huntington's Disease Program

THOMSON REUTERS

PTC Therapeutics Inc - Novartis to Assume Global Development and Commercial Responsibilities

THOMSON REUTERS

PTC Therapeutics to sell Priority Review Voucher for $150M

RBC Capital Remains a Hold on PTC Therapeutics (PTCT)

BUZZ-PTC Therapeutics falls after scrapping development of ALS drug

PTC Therapeutics Ends Utreloxastat Development After Rare Neurodegenerative Disease Trial Misses Goal, Analyst Maintains Outperform With Focus On Sepiapterin, Huntington's Programs

TD Cowen Remains a Hold on PTC Therapeutics (PTCT)

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Grifols shares rose 1.5%.PTC Therapeutics  signed a licensing deal with Novartis  unit Novartis Pharmaceuticals worth up to $2.9 billion for PTC518, its candidate treatment for Huntington's disease. PTC shares jumped 19% and Novartis was down 0.9%.Senti Biosciences  shares soared 377%. The company said Monday that two of three acute myeloid leukemia patients treated with its Senti-202 investigational cell therapy fo","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0211331839.USD","IE0002141913.USD","IE00B2B36J28.USD","BK4578","XLV","BK4581","LU0320765992.SGD","IE0009355771.USD","IE00BFTCPJ56.SGD","NVS","IE00BJT1NW94.SGD","RVMD","BK4139","LU0109394709.USD","IE00B4R5TH58.HKD","GRFS","BK4007","BK4532","PTCT","BK4539","BK4588","SNTI","IBB","IE00BJJMRZ35.SGD","LU0889565916.HKD","BK4585"],"gpt_icon":1},{"id":"2488602911","title":"Sector Update: Health Care Stocks Softer Monday Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2488602911","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488602911?lang=en_us&edition=fundamental","pubTime":"2024-12-03 02:42","pubTimestamp":1733164925,"startTime":"0","endTime":"0","summary":"Health care stocks were easing Monday afternoon, with the NYSE Health Care Index down 0.2% and the Health Care Select Sector SPDR Fund  shedding 0.3%.The iShares Biotechnology ETF  rose 0.1%.In corporate news, PTC Therapeutics  signed a licensing deal with Novartis  unit Novartis Pharmaceuticals worth up to $2.9 billion for PTC518, its candidate treatment for Huntington's disease. PTC shares jumped 18% and Novartis was down 0.9%.Senti Biosciences  shares soared 469%. The company said Monday that two of three acute myeloid leukemia patients treated with its Senti-202 investigational cell therapy for blood cancers achieved complete remission in a phase 1 trial.Gelteq  shares surged 28% after it said Monday its largest client in the US, Healthy Extracts, has increased its order of the company's collagen and Mynus sugar blocker gels by 50%.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IE00BJT1NW94.SGD","IE00BFTCPJ56.SGD","LU0109394709.USD","NVS","IE00B4R5TH58.HKD","GELS","BK4585","BK4139","BK4581","BK4588","BK4539","LU0320765992.SGD","BK4578","SNTI","IE00B2B36J28.USD","IE0009355771.USD","BK4007","LU0211331839.USD","PTCT","IE0002141913.USD","BK4532","LU0889565916.HKD","XLV","IBB","IE00BJJMRZ35.SGD"],"gpt_icon":1},{"id":"2488996872","title":"PTC Therapeutics Inks Licensing Pact With Novartis Worth Up To ~$3 Billion For Huntington's Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2488996872","media":"Benzinga","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488996872?lang=en_us&edition=fundamental","pubTime":"2024-12-03 01:58","pubTimestamp":1733162329,"startTime":"0","endTime":"0","summary":"On Monday, PTC Therapeutics, Inc. signed an exclusive global license and collaboration agreement with Novartis AG  for its PTC518 Huntington’s disease program, which includes related molecules.Under the agreement, PTC will receive an upfront payment of$1.0 billion, up to$1.9 billionin development, regulatory and sales milestones, a profit share in the U.S., and double-digit tiered royalties on ex-U.S. sales.Also Read: FDA Grants Conditional Approval For PTC Therapeutics’ Gene Therapy As First Ever With Direct Administration In Brain. PTC518 was discovered from PTC’s validated splicing platform and is currently being studied in the ongoing Phase 2 PIVOT-HD trial.Interim results reported inJune 2024showed that PTC518 treatment resulted in durable, dose-dependent reduction in blood and cerebrospinal fluid mutant Huntingtin protein levels as well as early signals of dose-dependent benefit on key clinical measurements at 12 months.PTC518 continues to demonstrate a favorable safety and toler","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/JnDcuNAm9P98YupVsAeQlA--~B/aD01NzY7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/0963d36c2ae7928ef1350222f2ef605d","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/JnDcuNAm9P98YupVsAeQlA--~B/aD01NzY7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/0963d36c2ae7928ef1350222f2ef605d"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ptc-therapeutics-inks-licensing-pact-175849656.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["NVS","LU1951200564.SGD","LU0889565916.HKD","PTC","BK4532","IE00B2B36J28.USD","BK4139","LU2362541273.HKD","LU2362541513.USD","PTCT","IE00BFTCPJ56.SGD","IE0002141913.USD","BK4585","LU0109394709.USD","BK4007","BK4578","LU2506952337.HKD","BK4588","IE00BJT1NW94.SGD","LU2477742899.HKD","BK4576","IE00BJJMRZ35.SGD","LU0211331839.USD","LU2362540622.SGD","IE0009355771.USD","BK4554","LU1721428347.USD","LU1923623000.USD","BK4023","IE00B4R5TH58.HKD","LU1951198990.SGD","LU2506952410.USD","LU0320765992.SGD"],"gpt_icon":0},{"id":"2488968773","title":"PTC Therapeutics Strikes Up to $2.9 Billion Licensing Deal With Novartis for Huntington's Disease Drug Candidate","url":"https://stock-news.laohu8.com/highlight/detail?id=2488968773","media":"MT Newswires","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488968773?lang=en_us&edition=fundamental","pubTime":"2024-12-02 23:41","pubTimestamp":1733154110,"startTime":"0","endTime":"0","summary":"PTC Therapeutics  signed a licensing deal with Novartis  unit Novartis Pharmaceuticals worth up to $2.9 billion for PTC518, its candidate treatment for Huntington's disease, the companies said in separate Monday statements.The Swiss pharmaceutical giant will pay PTC $1 billion upfront under the terms of the license and collaboration agreement, and up to $1.9 billion in development, regulatory and sales milestones. PTC will receive double-digit tiered royalties on sales outside the US.PTC and Novartis will share US profits and losses on a 40%-60% basis, respectively.\"This collaboration combines PTC's expertise in developing small molecule splicing therapies with Novartis's expertise in global development and commercialization of neuroscience therapies,\" PTC Chief Executive Matthew Klein said in a statement. \"We are excited to collaborate with Novartis to accelerate the potential of PTC518 for the hundreds of thousands of  patients worldwide.\". \"We look forward to building on our experti","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/B2FxTy3svxnvP3is5bzX7A--~B/aD03NTA7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/mt_newswires_premium_news_706/e00feef7b004d131e9dcd887c232b6b1","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/B2FxTy3svxnvP3is5bzX7A--~B/aD03NTA7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/mt_newswires_premium_news_706/e00feef7b004d131e9dcd887c232b6b1"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ptc-therapeutics-strikes-2-9-154150306.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0320765992.SGD","IE00B2B36J28.USD","LU0211331839.USD","LU2362541513.USD","BK4588","IE00BJT1NW94.SGD","LU0109394709.USD","BK4139","LU2362540622.SGD","BK4578","PTC","IE0009355771.USD","PTCT","LU2506952410.USD","LU2362541273.HKD","IE0002141913.USD","LU1951198990.SGD","BK4585","IE00B4R5TH58.HKD","LU2477742899.HKD","BK4532","LU1951200564.SGD","IE00BJJMRZ35.SGD","LU0889565916.HKD","LU2506952337.HKD","BK4554","NVS","BK4023","LU1721428347.USD","BK4576","LU1923623000.USD","BK4007","IE00BFTCPJ56.SGD"],"gpt_icon":0},{"id":"2488672301","title":"PTC Therapeutics Shares up 15.4% After Co Signs up to $2.9 Billion Licensing Deal With Novartis","url":"https://stock-news.laohu8.com/highlight/detail?id=2488672301","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488672301?lang=en_us&edition=fundamental","pubTime":"2024-12-02 22:36","pubTimestamp":1733150171,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nFWN3N30VR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0320765992.SGD","BK4139","PTCT","LU0109394709.USD","LU0889565916.HKD"],"gpt_icon":0},{"id":"2488674756","title":"Sector Update: Health Care Stocks Mixed Pre-Bell Monday","url":"https://stock-news.laohu8.com/highlight/detail?id=2488674756","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488674756?lang=en_us&edition=fundamental","pubTime":"2024-12-02 22:14","pubTimestamp":1733148871,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed pre-bell Monday as the iShares Biotechnology ETF  was up 0.2% and the Health Care Select Sector SPDR Fund  was 0.1% lower recently.PTC Therapeutics  shares advanced by over 17% after the company said it signed an exclusive global license and collaboration agreement for its PTC518 Huntington's disease program with a subsidiary of Novartis , and will receive a $1 billion upfront payment.Zai Lab  and NovoCure  said their phase 3 trial evaluating TTFields along with gemcitabine and nab-paclitaxel as a treatment for unresectable, locally advanced pancreatic adenocarcinoma achieved its primary endpoint, demonstrating a \"statistically significant\" improvement in median overall survival. NovoCure shares rose past 45% premarket.Olema Pharmaceuticals  shares were nearly 9% higher after the company said it has launched a clinical trial collaboration and supply agreement with Novartis  for a frontline metastatic breast cancer treatment.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0320765992.SGD","IE00B2B36J28.USD","LU0211331839.USD","BK4588","BK4534","IE00BJT1NW94.SGD","BK4505","LU0109394709.USD","BK4139","BK4578","BK4082","IE0009355771.USD","PTCT","BK4548","BK4581","IE0002141913.USD","BK4585","IE00B4R5TH58.HKD","ZLAB","BK4532","XLV","IE00BJJMRZ35.SGD","BK4531","LU0889565916.HKD","OLMA","IBB","NVS","BK4526","NVCR","BK4007","IE00BFTCPJ56.SGD"],"gpt_icon":0},{"id":"2488635675","title":"BUZZ-PTC Therapeutics rises on signing up to $2.9 billion licensing deal with Novartis","url":"https://stock-news.laohu8.com/highlight/detail?id=2488635675","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488635675?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:40","pubTimestamp":1733143208,"startTime":"0","endTime":"0","summary":"** Shares of PTC Therapeutics    rise 20.5% to $52.89 premarket       ** Co says drugmaker Novartis    will pay $1 billion upfront and up to $1.9 billion in milestone payments for PTCT's drug candidate, PTC518, which is being developed to treat Huntington's disease   ** NOVN will be responsible for the development, manufacturing and commercialization of the drug   ** PTCT and NOVN will share U.S. profits and losses for the drug on a 40/60 basis, respectively   ** Up to last close, stock was up 59.2% YTD ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1951198990.SGD","LU1951200564.SGD","PTCT","LU1923623000.USD","LU0889565916.HKD","LU2477742899.HKD","LU0109394709.USD","LU0320765992.SGD","LU2362541273.HKD","BK4576","BK4554","BK4139","LU1721428347.USD","LU2362541513.USD","LU2506952410.USD","LU2506952337.HKD","BK4023","BK4585","PTC","LU2362540622.SGD","BK4588"],"gpt_icon":0},{"id":"2488675119","title":"PTC Therapeutics Signs Exclusive Global License Deal With Novartis Unit for PTC518 Huntington's Disease Program; Shares Rise Premarket","url":"https://stock-news.laohu8.com/highlight/detail?id=2488675119","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488675119?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:31","pubTimestamp":1733142684,"startTime":"0","endTime":"0","summary":"PTC Therapeutics  said Monday that it signed an exclusive global license and collaboration agreement for its PTC518 Huntington's disease program with a subsidiary of Novartis , and will receive a $1 billion upfront payment.The company said it will also be entitled to additional payments of up to $1.9 billion based on development, regulatory and sales milestones, plus a profit share in the US and double-digit tiered royalties on international sales.As part for the deal, PTC Therapeutics said Novartis will be in charge of PTC518's development, manufacturing and commercialization after the completion of the ongoing placebo-controlled portion of a phase 2 trial on PTC518, which is expected in the first half of 2025.The transaction is expected to close in Q1 2025, said PTC Therapeutics.PTC Therapeutics shares were up over 20% in recent premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU1951198990.SGD","NVS","LU1951200564.SGD","PTCT","LU1923623000.USD","LU0889565916.HKD","LU2477742899.HKD","LU0109394709.USD","IE00B4R5TH58.HKD","LU0320765992.SGD","IE00BJT1NW94.SGD","IE00B2B36J28.USD","BK4578","LU2362541273.HKD","BK4576","BK4554","BK4139","IE0002141913.USD","LU1721428347.USD","LU2362541513.USD","LU2506952410.USD","LU2506952337.HKD","BK4023","BK4585","IE0009355771.USD","BK4007","PTC","LU2362540622.SGD","BK4532","BK4588","LU0211331839.USD","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD"],"gpt_icon":0},{"id":"2488673304","title":"PTC Therapeutics signs up to $1.9 billion licensing deal with Novartis","url":"https://stock-news.laohu8.com/highlight/detail?id=2488673304","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488673304?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:10","pubTimestamp":1733141411,"startTime":"0","endTime":"0","summary":"Dec 2  - PTC Therapeutics    has entered into a licensing deal with a unit of Novartis AG    for up to $1.9 billion, the company said on Monday, for its experimental drug being developed for a rare neurological disorder.    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Novartis AG NOVN.S:PTC THERAPEUTICS ENTERS INTO A","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nTUA83VMQH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0320765992.SGD","PTCT","LU0889565916.HKD","BK4139","LU0109394709.USD"],"gpt_icon":0},{"id":"2488567809","title":"PTC Therapeutics Shares Jump 14.1% Premarket After Agreement With Novartis for Huntington's Disease Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2488567809","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488567809?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:05","pubTimestamp":1733141112,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nL3N3N30OF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0889565916.HKD","BK4139","LU0320765992.SGD","PTCT","LU0109394709.USD"],"gpt_icon":0},{"id":"2488784886","title":"PTC Therapeutics Inc - to Receive $1 Billion in Cash at Closing","url":"https://stock-news.laohu8.com/highlight/detail?id=2488784886","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488784886?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:00","pubTimestamp":1733140807,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nTUA83VMQH:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PTCT","LU0889565916.HKD","LU0109394709.USD","LU0320765992.SGD","BK4139"],"gpt_icon":0},{"id":"2488678174","title":"PTC Therapeutics Enters Into a Global License and Collaboration Agreement With Novartis for PTC518 Huntington's Disease Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2488678174","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488678174?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:00","pubTimestamp":1733140807,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nTUA83VMQH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0109394709.USD","PTCT","LU0320765992.SGD","BK4139","LU0889565916.HKD"],"gpt_icon":0},{"id":"2488267845","title":"PTC Therapeutics Inc - Novartis to Assume Global Development and Commercial Responsibilities","url":"https://stock-news.laohu8.com/highlight/detail?id=2488267845","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2488267845?lang=en_us&edition=fundamental","pubTime":"2024-12-02 20:00","pubTimestamp":1733140807,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241202:nTUA83VMQH:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0320765992.SGD","PTCT","LU0889565916.HKD","LU0109394709.USD","BK4139"],"gpt_icon":0},{"id":"2486931803","title":"PTC Therapeutics to sell Priority Review Voucher for $150M","url":"https://stock-news.laohu8.com/highlight/detail?id=2486931803","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486931803?lang=en_us&edition=fundamental","pubTime":"2024-11-28 20:11","pubTimestamp":1732795886,"startTime":"0","endTime":"0","summary":"PTC Therapeutics  announced that it has entered into an agreement to sell its Rare Pediatric Disease Priority Review Voucher for $150M upon the closing of the transaction. PTC was granted the PRV on November 13 along with the U.S. FDA approval of KEBILIDI for the treatment of children and adults with AADC deficiency, including the full spectrum of disease severity. The transaction is subject to customary closing conditions, including expiration of the applicable waiting period under the Hart-Scott Rodino Antitrust Improvements Act.Unlock your investing potential with TipRanks Premium - Now At 40% OFF!Make smarter investments with weekly expert stock picks from the Smart Investor Newsletter. PTC Therapeutics: Phase 2 CardinALS study did not meet its primary endpoint. PTC Therapeutics price target raised to $62 from $51 at JPMorgan. PTC Therapeutics price target raised to $45 from $43 at Barclays. PTC Therapeutics’ AADC deficiency gene therapy granted FDA approval. PTC Therapeutics price","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/6MInUe1T4fs5TaG11G3efw--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/87b9ff78d08b9d461f46ab67f57ff730","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/6MInUe1T4fs5TaG11G3efw--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/87b9ff78d08b9d461f46ab67f57ff730"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/ptc-therapeutics-sell-priority-review-121126641.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ptc-therapeutics-sell-priority-review-121126641.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0889565916.HKD","LU0320765992.SGD","LU2362541273.HKD","LU2362541513.USD","PTCT","LU2506952410.USD","LU2477742899.HKD","BK4554","BK4585","BK4576","BK4139","BK4588","LU1721428347.USD","BK4023","LU2506952337.HKD","LU2362540622.SGD","LU1951200564.SGD","LU0109394709.USD","LU1923623000.USD","PTC","LU1951198990.SGD"],"gpt_icon":0},{"id":"2486133935","title":"RBC Capital Remains a Hold on PTC Therapeutics (PTCT)","url":"https://stock-news.laohu8.com/highlight/detail?id=2486133935","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486133935?lang=en_us&edition=fundamental","pubTime":"2024-11-28 09:48","pubTimestamp":1732758483,"startTime":"0","endTime":"0","summary":"In a report released on November 25, Brian Abrahams from RBC Capital maintained a Hold rating on PTC Therapeutics (PTCT – Research Report), with a ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/rbc-capital-remains-a-hold-on-ptc-therapeutics-ptct-4?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/rbc-capital-remains-a-hold-on-ptc-therapeutics-ptct-4?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU1923623000.USD","BK4207","LU0109394709.USD","LU1951200564.SGD","BK4023","BK4588","LU1721428347.USD","LU0320765992.SGD","BK4585","LU2362541513.USD","LU2477742899.HKD","LU1951198990.SGD","LU2506952337.HKD","BK4554","LU0889565916.HKD","BK4139","PTC","LU2362541273.HKD","LU2506952410.USD","PTCT","BK4576","LU2362540622.SGD"],"gpt_icon":0},{"id":"2486874817","title":"BUZZ-PTC Therapeutics falls after scrapping development of ALS drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2486874817","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486874817?lang=en_us&edition=fundamental","pubTime":"2024-11-28 00:42","pubTimestamp":1732725727,"startTime":"0","endTime":"0","summary":"BUZZ-PTC Therapeutics falls after scrapping development of ALS drug ** Shares of PTC Therapeutics PTCT.O fall 1.3% to $45.43 in morning trade ** Company, late on Tuesday, said it has discontinued development of its experimental drug to treat amyotrophic lateral sclerosis ** The drug, utreloxastat, failed to slow disease progression, the main goal, in a mid-stage trial - PTCT   ** \"While this outcome is unfortunate, expectations were low given that drug development in ALS has been difficult and supporting evidence for utreloxastat in ALS was limited\" - TD Cowen analysts** ALS is a rare neurological disease that can break down nerve cells, in the brain and spinal cord, responsible for muscle movements** Including session moves, stock up about 64% YTD   ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nL3N3MY0U9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0889565916.HKD","LU0320765992.SGD","PTCT","LU0109394709.USD","BK4139"],"gpt_icon":0},{"id":"2486822810","title":"PTC Therapeutics Ends Utreloxastat Development After Rare Neurodegenerative Disease Trial Misses Goal, Analyst Maintains Outperform With Focus On Sepiapterin, Huntington's Programs","url":"https://stock-news.laohu8.com/highlight/detail?id=2486822810","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486822810?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:51","pubTimestamp":1732711909,"startTime":"0","endTime":"0","summary":"On Tuesday, PTC Therapeutics Inc  revealed data from the global Phase 2 placebo-controlled CardinALS study of Utreloxastat in amyotrophic lateral sclerosis patients.The study did not meet its primary endpoint of slowing disease progression on the composite ALSFRS-R and mortality analysis.Also Read: FDA Grants Conditional Approval For PTC Therapeutics’ Gene Therapy As First Ever With Direct Administration In Brain. While modest numerical benefit was recorded on the primary endpoint, and a favorable clinical effect was correlated with lowering plasma neurofilament light chain , a biomarker of neuronal damage, statistical significance was not achieved . In addition, significance was not achieved on the secondary efficacy endpoints.Amyotrophic lateral sclerosis , sometimes referred to as motor neuron disease orLou Gehrig’sdisease, is a rare neurodegenerative disease that affects motor neurons in the brain and spinal cord.William Blair notes that while the CardinALS trial results were 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