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Rhythm Pharmaceuticals Inc.

76.90

-5.0000-6.11%

Volume:683.63K

Turnover:53.81M

Market Cap:5.25B

PE:-24.76

High:83.65

Open:81.00

Low:76.51

Close:81.90

52wk High:122.20

52wk Low:45.91

Shares:68.29M

Float Shares:55.48M

Volume Ratio:0.53

T/O Rate:1.23%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.1057

EPS(LYR):-3.1100

ROE:-90.45%

ROA:-27.51%

PB:37.76

PE(LYR):-24.73

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Overview Company News Filings

Rhythm Pharma's obesity drug fails to meet main goal in late-stage trial

Rhythm Pharmaceuticals Shares Fall About 13% to $78.58 After the Bell Following Announcement That Emanate Phase 3 Trial Didn't Meet Primary Endpoints

THOMSON REUTERS

Rhythm Pharmaceuticals reports Phase 3 EMANATE trial misses primary endpoints for setmelanotide across four genetic substudies

Rhythm Pharmaceuticals Inc: Plans to Continue Analysis of Emanate Dataset & Evaluate Potential Clinical Development Paths Forward

THOMSON REUTERS

Rhythm Pharmaceuticals Inc - No New Safety Signals Observed With Setmelanotide in Emanate Trial

THOMSON REUTERS

Rhythm Pharmaceuticals price target raised to $143 from $136 at Wells Fargo

A Look At Rhythm Pharmaceuticals (RYTM) Valuation After New Trial Data Earnings And Financing Updates

Simply Wall St.

Rhythm Pharmaceuticals Corporate Controller and CAO Christopher Paul German Disposes of Common Shares

Analysts’ Opinions Are Mixed on These Healthcare Stocks: Altimmune (ALT), Rhythm Pharmaceuticals (RYTM) and Cormedix (CRMD)

Rhythm Pharmaceuticals Is Maintained at Buy by HC Wainwright & Co.

Rhythm Says New Late-Stage Data for Obesity Drug Shows Strong Weight Loss, Hunger Reduction

MT Newswires Live

Rhythm Pharmaceuticals price target lowered to $140 from $141 at Canaccord

Rhythm Pharmaceuticals Nears Key FDA Calls With Global Growth Potential

Simply Wall St.

Rhythm announces additional data from Phase 3 trial of setmelanotide

BRIEF-Rhythm Pharmaceuticals Says PDUFA Goal Date For Setmelanotide Is March 20, 2026

Rhythm Pharmaceuticals reports positive Phase 3 TRANSCEND data for setmelanotide in acquired hypothalamic obesity

Rhythm Pharmaceuticals Announces Additional Positive Data From Phase 3 Transcend Trial of Setmelanotide in Patients With Acquired Hypothalamic Obesity

THOMSON REUTERS

Rhythm Pharmaceuticals Inc - Primary Endpoint Achieved With 16.4% Bmi Reduction

THOMSON REUTERS

Rhythm Pharmaceuticals Inc - Pdufa Goal Date for Setmelanotide Is March 20, 2026

THOMSON REUTERS

Rhythm Pharmaceuticals (RYTM) Receives a Buy from Jefferies

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Rhythm reported topline results from the global Phase 3 EMANATE trial of setmelanotide in four genetic substudies of MC4R-pathway obesity, and all four substudies did not meet their pre-specified primary endpoints at Week 52. In the prespecified modified ITT analysis, placebo-adjusted BMI reductions at Week 52 were 0% or greater in POMC/PCSK1 heterozygous patients  and SRC1  patients (-4%). Post hoc analyses using last observation carried forward found statistically significant BMI reductions at Week 52 in POMC/PCSK1 heterozygous patients  and SRC1  patients . The company said the safety profile was consistent with prior studies, with common adverse events including skin hyperpigmentation and injection-site reactions. The results were announced with a conference call scheduled for later the same day, and no separate future scientific presentation was specified","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nNDL7fQJvC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0314104364.USD","IE00BN0W2T93.GBP","BK4585","NDAQ","LU2210150020.SGD","LU2095319765.USD","RYTM","IE00B3QW5Z07.USD","IE00BN0W2W23.USD","SG9999014039.USD","BK4139","IE00B64PRP62.GBP","BK4588","SG9999014005.SGD","IE00BKPKM429.USD","SG9999014021.USD","SG9999014013.SGD","IE00BN0W2V16.EUR","IE00BGHQF748.EUR","BK4112","LU2210149790.SGD"],"gpt_icon":0},{"id":"2620960714","title":"Rhythm Pharmaceuticals Inc: Plans to Continue Analysis of Emanate Dataset & Evaluate Potential Clinical Development Paths Forward","url":"https://stock-news.laohu8.com/highlight/detail?id=2620960714","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620960714?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:01","pubTimestamp":1773691260,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nTUA1NY8SX:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4585","RYTM","BK4588","BK4139"],"gpt_icon":0},{"id":"2620249600","title":"Rhythm Pharmaceuticals Inc - No New Safety Signals Observed With Setmelanotide in Emanate Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2620249600","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620249600?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:01","pubTimestamp":1773691260,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nTUA1NY8SX:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4588","BK4585","RYTM"],"gpt_icon":0},{"id":"2618135828","title":"Rhythm Pharmaceuticals price target raised to $143 from $136 at Wells Fargo","url":"https://stock-news.laohu8.com/highlight/detail?id=2618135828","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618135828?lang=en_us&edition=fundamental","pubTime":"2026-03-12 18:37","pubTimestamp":1773311850,"startTime":"0","endTime":"0","summary":"Wells Fargo raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $143 from $136 and keeps an Overweight rating on the shares. The fir...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/rhythm-pharmaceuticals-price-target-raised-to-143-from-136-at-wells-fargo-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/rhythm-pharmaceuticals-price-target-raised-to-143-from-136-at-wells-fargo-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0310800965.SGD","LU0980610538.SGD","LU1267930573.SGD","LU0128525689.USD","LU0256863811.USD","LU0320765489.SGD","LU0477156953.USD","LU1814569148.SGD","LU0310799852.SGD","LU0149725797.USD","LU0708994859.HKD","LU0648001328.SGD","BK4139","BK4585","LU0130102774.USD","LU0251131958.USD","LU1668664300.SGD","IE000M9KFDE8.USD","IE00B7SZLL34.SGD","LU0314106906.USD","BK4588","LU0154236417.USD","LU1074936037.SGD","LU0417517546.SGD","LU0130517989.USD","LU1035773651.USD","LU1201861249.SGD","LU2361044949.HKD","LU0683600562.USD","BK4501","LU0868494617.USD","IE0002270589.USD","BK4559","BK4207","LU0289960550.SGD","LU2361045086.USD","LU1267930227.SGD","LU0052756011.USD","LU0072461881.USD","LU0175139822.USD","LU0310800379.SGD","LU1363072403.SGD","LU0742534661.SGD","RYTM","IE00B19Z3B42.SGD","LU0162691827.USD","LU0208291251.USD","LU0048573561.USD","LU0868494708.USD","LU0640476718.USD"],"gpt_icon":0},{"id":"2618418670","title":"A Look At Rhythm Pharmaceuticals (RYTM) Valuation After New Trial Data Earnings And Financing Updates","url":"https://stock-news.laohu8.com/highlight/detail?id=2618418670","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2618418670?lang=en_us&edition=fundamental","pubTime":"2026-03-10 05:21","pubTimestamp":1773091290,"startTime":"0","endTime":"0","summary":"Why Rhythm Pharmaceuticals is back in focus after fresh trial data\nRhythm Pharmaceuticals (RYTM) is back on investors’ radar after new positive Phase 3 TRANSCEND data for setmelanotide in acquired hypothalamic obesity, alongside advancing US and Japan regulatory filings and fresh financing moves.\nSee our latest analysis for Rhythm Pharmaceuticals.\nAt a share price of $93.52, Rhythm’s 1-day share price return of 2.25% and recent product and financing announcements sit against a softer 30-day...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rytm/rhythm-pharmaceuticals/news/a-look-at-rhythm-pharmaceuticals-rytm-valuation-after-new-tr","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rytm/rhythm-pharmaceuticals/news/a-look-at-rhythm-pharmaceuticals-rytm-valuation-after-new-tr","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["RYTM"],"gpt_icon":0},{"id":"2617076658","title":"Rhythm Pharmaceuticals Corporate Controller and CAO Christopher Paul German Disposes of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2617076658","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617076658?lang=en_us&edition=fundamental","pubTime":"2026-03-07 05:51","pubTimestamp":1772833906,"startTime":"0","endTime":"0","summary":"Christopher Paul German, Corporate Controller and CAO of Rhythm Pharmaceuticals Inc., reported a disposal of common shares. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Rhythm Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on March 06, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260306:nNDL2yPhJp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Rhythm Pharmaceuticals Corporate Controller and CAO Christopher Paul German Disposes of Common Shares","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","RYTM","BK4588","BK4139"],"gpt_icon":0},{"id":"2617524542","title":"Analysts’ Opinions Are Mixed on These Healthcare Stocks: Altimmune (ALT), Rhythm Pharmaceuticals (RYTM) and Cormedix (CRMD)","url":"https://stock-news.laohu8.com/highlight/detail?id=2617524542","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617524542?lang=en_us&edition=fundamental","pubTime":"2026-03-06 00:30","pubTimestamp":1772728250,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Altimmune (ALT – Research Report), Rhythm Pharmaceuticals (RYTM –...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-altimmune-alt-rhythm-pharmaceuticals-rytm-and-cormedix-crmd-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-altimmune-alt-rhythm-pharmaceuticals-rytm-and-cormedix-crmd-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4588","BK4137","BK4585","LU0029874061.USD","XBI","XLV","LU1878469433.USD","BK4139","HCSG","LU0128526141.USD","ALT","BK4581","BK4599","RYTM","BK4007","LABU","CRMD"],"gpt_icon":0},{"id":"2616539463","title":"Rhythm Pharmaceuticals Is Maintained at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2616539463","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616539463?lang=en_us&edition=fundamental","pubTime":"2026-03-02 22:25","pubTimestamp":1772461500,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/RYTM/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  March 02, 2026 09:25 ET (14:25 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RYTM","BK4585","BK4139","BK4588"],"gpt_icon":0},{"id":"2616339393","title":"Rhythm Says New Late-Stage Data for Obesity Drug Shows Strong Weight Loss, Hunger Reduction","url":"https://stock-news.laohu8.com/highlight/detail?id=2616339393","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616339393?lang=en_us&edition=fundamental","pubTime":"2026-03-02 19:44","pubTimestamp":1772451899,"startTime":"0","endTime":"0","summary":"Rhythm Pharmaceuticals  on Sunday shared new results from a late-stage trial of its drug setmelanotide for acquired hypothalamic obesity, a rare condition that causes extreme weight gain and hunger.The data showed that after 52 weeks, patients taking the drug saw their body mass index  drop by 16.4% on average. At the same time, patients on placebo saw their BMI rise by 2.4%.The drug also reduced hunger, the company said. Patients aged 12 and older reported a 2.5-point drop in weekly hunger scores, compared with a 1.3-point drop in the placebo group, it said.The new data includes additional patients from Japan, and others added beyond the main study group, according to the company.The US FDA is reviewing the drug, with a Prescription Drug User Fee Act decision expected by March 20, Rhythm said.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4588","SSI","BK4585","BK4157","BK4139","BMI","RYTM"],"gpt_icon":0},{"id":"2616336022","title":"Rhythm Pharmaceuticals price target lowered to $140 from $141 at Canaccord","url":"https://stock-news.laohu8.com/highlight/detail?id=2616336022","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616336022?lang=en_us&edition=fundamental","pubTime":"2026-03-02 19:37","pubTimestamp":1772451463,"startTime":"0","endTime":"0","summary":"Canaccord lowered the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $140 from $141 and keeps a Buy rating on the shares. The firm said it...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/rhythm-pharmaceuticals-price-target-lowered-to-140-from-141-at-canaccord-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/rhythm-pharmaceuticals-price-target-lowered-to-140-from-141-at-canaccord-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4585","BK4588","RYTM"],"gpt_icon":0},{"id":"2616066228","title":"Rhythm Pharmaceuticals Nears Key FDA Calls With Global Growth Potential","url":"https://stock-news.laohu8.com/highlight/detail?id=2616066228","media":"Simply Wall St.","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616066228?lang=en_us&edition=fundamental","pubTime":"2026-03-02 09:24","pubTimestamp":1772414695,"startTime":"0","endTime":"0","summary":"Rhythm Pharmaceuticals is moving toward a key FDA decision for IMCIVREE in acquired hypothalamic obesity, with preparations underway for a potential U.S. approval and commercial launch.\nThe company has received constructive FDA feedback at its end of Phase 2 meeting for oral candidate bivamelagon, supporting plans to progress into Phase 3.\nRhythm is also working on broader commercial access, reimbursement, and geographic expansion in Europe and Japan for its rare neuroendocrine disease...","market":"us","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rytm/rhythm-pharmaceuticals/news/rhythm-pharmaceuticals-nears-key-fda-calls-with-global-growt","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rytm/rhythm-pharmaceuticals/news/rhythm-pharmaceuticals-nears-key-fda-calls-with-global-growt","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4585","BK4588","BK4139","RYTM"],"gpt_icon":0},{"id":"2616711398","title":"Rhythm announces additional data from Phase 3 trial of setmelanotide","url":"https://stock-news.laohu8.com/highlight/detail?id=2616711398","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616711398?lang=en_us&edition=fundamental","pubTime":"2026-03-02 05:10","pubTimestamp":1772399436,"startTime":"0","endTime":"0","summary":"Rhythm Pharmaceuticals (RYTM) announced additional data from its global Phase 3 TRANSCEND trial of setmelanotide in patients with acquired hypothal...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/rhythm-announces-additional-data-from-phase-3-trial-of-setmelanotide-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/rhythm-announces-additional-data-from-phase-3-trial-of-setmelanotide-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4588","BK4139","RYTM","BK4585"],"gpt_icon":0},{"id":"2616873406","title":"BRIEF-Rhythm Pharmaceuticals Says PDUFA Goal Date For Setmelanotide Is March 20, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2616873406","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616873406?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:31","pubTimestamp":1772386289,"startTime":"0","endTime":"0","summary":"BRIEF-Rhythm Pharmaceuticals Says PDUFA Goal Date For Setmelanotide Is March 20, 2026March 1 (Reuters) - Rhythm Pharmaceuticals Inc RYTM.O:RHYTHM PHARMACEUTICALS ANNOUNCES ADDITIONAL POSITIVE DATA FRO","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABW78M:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","BK4139","BK4588","RYTM"],"gpt_icon":0},{"id":"2616873448","title":"Rhythm Pharmaceuticals reports positive Phase 3 TRANSCEND data for setmelanotide in acquired hypothalamic obesity","url":"https://stock-news.laohu8.com/highlight/detail?id=2616873448","media":"Reuters","labels":["dataReport","merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616873448?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:30","pubTimestamp":1772386216,"startTime":"0","endTime":"0","summary":"Rhythm Pharmaceuticals reported additional 52-week data from its global Phase 3 TRANSCEND trial of setmelanotide in patients with acquired hypothalamic obesity, including 12 patients from Japan and 10 supplemental patients beyond the primary pivotal cohort. Across all patients , the company reported a -18.8% placebo-adjusted difference in BMI reduction at 52 weeks; mean BMI change was -16.4% with setmelanotide  versus +2.4% with placebo , and in patients aged 12 and older, weekly average most hunger scores decreased by 2.5 points with setmelanotide versus 1.3 points with placebo. The company said topline results from the pre-specified 120-patient pivotal cohort were previously disclosed in April 2025, and that its U.S. sNDA for this indication is under FDA review with a March 20, 2026 PDUFA goal date.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nNDL10scDQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,merge","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014005.SGD","IE00B3QW5Z07.USD","IE00BGHQF748.EUR","LU0314104364.USD","IE00B64PRP62.GBP","LU2210150020.SGD","BK4585","BK4588","BK4112","LU2095319765.USD","LU2210149790.SGD","RYTM","NDAQ","IE00BKPKM429.USD","SG9999014021.USD","BK4139","SG9999014039.USD","SG9999014013.SGD"],"gpt_icon":0},{"id":"2616887341","title":"Rhythm Pharmaceuticals Announces Additional Positive Data From Phase 3 Transcend Trial of Setmelanotide in Patients With Acquired Hypothalamic Obesity","url":"https://stock-news.laohu8.com/highlight/detail?id=2616887341","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616887341?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:30","pubTimestamp":1772386200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABW78M:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4585","BK4588","RYTM","BK4139"],"gpt_icon":0},{"id":"2616873415","title":"Rhythm Pharmaceuticals Inc - Primary Endpoint Achieved With 16.4% Bmi Reduction","url":"https://stock-news.laohu8.com/highlight/detail?id=2616873415","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616873415?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:30","pubTimestamp":1772386200,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABW78M:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RYTM","BK4588","BK4585","BK4139"],"gpt_icon":0},{"id":"2616873413","title":"Rhythm Pharmaceuticals Inc - Pdufa Goal Date for Setmelanotide Is March 20, 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2616873413","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616873413?lang=en_us&edition=fundamental","pubTime":"2026-03-02 01:30","pubTimestamp":1772386200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260301:nTUABW78M:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RYTM","BK4585","BK4139","BK4588"],"gpt_icon":0},{"id":"2614865803","title":"Rhythm Pharmaceuticals (RYTM) Receives a Buy from Jefferies","url":"https://stock-news.laohu8.com/highlight/detail?id=2614865803","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614865803?lang=en_us&edition=fundamental","pubTime":"2026-02-28 00:56","pubTimestamp":1772211368,"startTime":"0","endTime":"0","summary":"Jefferies analyst Dennis Ding maintained a Buy rating on Rhythm Pharmaceuticals today and set a price target of $125.00. 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