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SPYRE THERAPEUTICS INC

24.26

+0.43001.80%

Post-market: 24.260.00000.00%16:29 EDT

Volume:488.41K

Turnover:11.88M

Market Cap:1.88B

PE:-8.51

High:24.68

Open:23.79

Low:23.78

Close:23.83

52wk High:40.26

52wk Low:10.91

Shares:77.50M

Float Shares:63.83M

Volume Ratio:0.55

T/O Rate:0.77%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.8512

EPS(LYR):-3.1802

ROE:-49.83%

ROA:-28.48%

PB:6.27

PE(LYR):-7.63

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News

Spyre Therapeutics to Participate in Upcoming November Investor Conferences

Spyre Therapeutics (SYRE): Valuation Spotlight After New Clinical Data for Lead Anti-TL1A Therapy SPY072

Simply Wall St.

Spyre Therapeutics Reports Positive Six-Month Phase 1 Data for Anti-TL1A Antibody SPY072 in Rheumatic Diseases

Spyre Therapeutics Announces Poster Presentations at American College of Rheumatology (ACR) Convergence 2025

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(NASDAQ: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redef","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/10/29/3176866/0/en/Spyre-Therapeutics-to-Participate-in-Upcoming-November-Investor-Conferences.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4581","BK4585","BK4539","SYRE","LENZ","XBI","BK4007","XLV","LABU","BK4588"],"gpt_icon":0},{"id":"2578689361","title":"Spyre Therapeutics (SYRE): Valuation Spotlight After New Clinical Data for Lead Anti-TL1A Therapy SPY072","url":"https://stock-news.laohu8.com/highlight/detail?id=2578689361","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578689361?lang=en_us&edition=fundamental","pubTime":"2025-10-26 04:22","pubTimestamp":1761423754,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics has just presented new data on its lead anti-TL1A therapy, SPY072, at the ACR Convergence Congress. The updates show the drug’s unique dosing profile, safety, and early support for ongoing development in rheumatic diseases.\nSee our latest analysis for Spyre Therapeutics.\nSparking investor attention, Spyre Therapeutics recently raised $275 million via a follow-on equity offering and has enjoyed a strong rebound. Its 30-day share price return is up 37.5%, marking a sharp turn...","market":"us","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-valuation-spotlight-after-new-clinic","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-valuation-spotlight-after-new-clinic","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SYRE","BK4139"],"gpt_icon":0},{"id":"2577137245","title":"Spyre Therapeutics Reports Positive Six-Month Phase 1 Data for Anti-TL1A Antibody SPY072 in Rheumatic Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2577137245","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2577137245?lang=en_us&edition=fundamental","pubTime":"2025-10-24 20:00","pubTimestamp":1761307226,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc. announced new scientific presentations at the upcoming American College of Rheumatology  Convergence Congress. The company will present follow-up data from its Phase 1 study of SPY072, an investigational anti-TL1A monoclonal antibody being developed for rheumatic diseases. Interim results indicate that SPY072 is well tolerated and exhibits a pharmacokinetic profile that may support maintenance dosing every three or six months. In addition, new preclinical data will be presented showing that anti-TL1A antibody treatment demonstrated efficacy comparable to or exceeding etanercept in a rodent model of collagen-induced arthritis. These data provide further support for the ongoing SKYWAY Phase 2 study evaluating SPY072 in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis. The posters will be available for viewing during the ACR Convergence Congress.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelli","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251024:nNDLmMH4j:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"gpt_icon":0},{"id":"2577351598","title":"Spyre Therapeutics Announces Poster Presentations at American College of Rheumatology (ACR) Convergence 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2577351598","media":"GlobeNewswire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2577351598?lang=en_us&edition=fundamental","pubTime":"2025-10-24 20:00","pubTimestamp":1761307200,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., Oct.  24, 2025  (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. 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