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Mirum Pharmaceuticals, Inc.

96.92

+0.61000.63%

成交量：12.03萬

成交額：1,161.08萬

市值：62.93億

市盈率：-6.88

高：97.35

開：96.31

低：95.49

收：96.31

52周最高：130.00

52周最低：63.23

股本：6,493.22萬

流通股本：5,641.51萬

量比：0.38

換手率：0.21%

股息：- -

股息率：- -

每股收益(TTM):-14.0800

每股收益(LYR):-0.4700

淨資產收益率：-702.97%

總資產收益率：-6.79%

市淨率：-603.84

市盈率(LYR):-206.21

資料載入中...

總覽公司新聞資訊公告

美國研究綜述-Adobe、耐克、Watts Water Technologies

Mirum製藥與因塞特醫療公布Zilurgisertib治療進行性骨化性纖維發育不良的關鍵2期研究積極結果

Mirum Pharmaceuticals在歐洲肝病研究學會國際肝病大會上公布罕見肝病項目新數據

美國研究綜述-CAVA集團、Eagle Materials、Vertiv控股

美國研究綜述-CAVA集團、Eagle Materials、Vertiv控股

美國研究綜述-思科、DTE能源、美滿科技

異動解讀 | 藥物研究進展獲分析師看好，Mirum Pharmaceuticals盤中大漲5.26%

Mirum Pharmaceuticals完成6億美元可轉換優先票據定價並部分贖回2029年到期票據

熱門話題-Mirum Pharma股價下跌，因宣佈達成6億美元可轉換債券交易

熱門話題-Mirum Pharma股價上漲，因其肝病藥物在臨床試驗中達到主要目標

Mirum公司治療罕見肝病的藥物在中期研究中達到主要目標

Mirum製藥Volixibat安全性特徵與IBAT抑制作用一致主要表現為胃腸道事件及肝酶升高

Mirum Pharmaceuticals預計2027年第一季度公布Volixibat治療PBC的Vantage二期B階段研究頂線數據

Mirum製藥公司計劃2026年夏季與FDA召開Volixibat治療PSC的新藥申請前會議擬於2026年下半年提交NDA

Mirum製藥Volixibt實現瘙癢評分降低2.72分較安慰劑組優勢達1.64分（P<0.0001）

Mirum Pharmaceuticals宣佈Volixibat治療原發性硬化性膽管炎的Vistas研究達到主要終點

Mirum製藥宣佈Brelovitug治療慢性丁型肝炎的Azure-1研究2B階段達成主要終點

熱門話題-Mirum Pharma股價上漲，因其丁型肝炎藥物達成主要目標

Mirum製藥完成Livmarli®治療罕見膽汁淤積性肝病三期擴展研究患者招募

Mirum製藥公司：Azure-1與Azure-4預計將於2027年在美國提交BLA申請並上市

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Cowen将目标价从275美元上调至320美元以下是路透周四报导的针对美国公司的研究行动摘要。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260702:nL4T4340IC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B5TLWC47.USD","LU0965509101.SGD","LU1430594728.SGD","LU1720051017.SGD","BK4547","BK4548","LU0240877869.USD","LU0868494708.USD","LU2236285917.USD","LU0006306889.USD","WTS","LU0787776722.HKD","LU0128525689.USD","LU0323240290.USD","LU0289739343.SGD","SGXZ81514606.USD","LU1084165304.USD","LU0082616367.USD","LU1267930227.SGD","LU0788109394.HKD","PEG","LU0052756011.USD","BK4566","LU0345774631.USD","LU1267930730.SGD","LU0234572021.USD","LU0792757196.USD","LU0122376428.USD","LU0300736062.USD","LU1303367103.USD","LU0957791311.USD","BK4527","LU1119994496.HKD","LU0708994859.HKD","BK4146","LU0081259029.USD","LU0130102774.USD","SG9999000418.SGD","SG9999001424.SGD","BK4184","IE00BMG7P694.USD","LU0348723411.USD","LU0256331488.USD","IE0009356076.USD","LU1267930813.SGD","BK4533","BK4178","LU0889565833.HKD","IE00B3CCJ963.GBP","SGXZ51526630.SGD","LU2098885051.SGD","BK4554","LU2500361329.USD","BK4161","LU2458330243.SGD","BK4561","LU0823411888.USD","LU0300736492.USD","LU1878469433.USD","IE00BYQQ9H92.USD","LU0157215616.USD","LU0061475181.USD","LU0289961442.SGD","BK4543","BK4592","LU0472753341.HKD","LU2023251221.USD","LU2210149790.SGD","LU2089284900.SGD","LU0240878834.USD","LU0070302665.USD","BK4581","BK4528","LU0109392836.USD","LU1712237335.SGD","LU1778281490.HKD","LU0965509283.SGD","BK4534","IE00BGHQF524.EUR","LU0208291251.USD","LU0128525929.USD","IE00BQXX3F31.USD","LU1674673428.USD","MIRM","LU0069063385.USD","BK4588","BK4558","LU2360032135.SGD","BK4139","LU0198837287.USD","LU0511384066.AUD","BK4213","LU0965509010.AUD","LU0266512127.USD","LU0345774391.USD","LU1803068979.SGD","LU2265009873.SGD","LU0889566641.SGD","BK4212","ONON","LU1815333072.USD","LU0053666078.USD","BK4208","VOYA","LU2357305700.SGD","LU0557290698.USD","LU2125154935.USD","LU0314104364.USD","LU1674673691.USD","ADBG","BK4567","LU0323239441.USD","LU0170899867.USD","LU2346227817.USD","LU0708995401.HKD","LU1823568750.SGD","IE00BFXG0V08.USD","LU1261432733.SGD","LU1633808545.USD","LU1235294995.USD","BK4135","IE00BQXX3C00.GBP","LU0868494617.USD","LU2095319765.USD","LU1720051108.HKD","LU0158827948.USD","LU0648001328.SGD","BK4122","GIS","IE00BMG7P587.USD","NKE","LU0786609619.USD","LU0456854461.SGD","IE00BMG7P926.USD","SGXZ99366536.SGD","LU2125154778.USD","LU1366333091.USD","IE00B2Q91V27.USD","LU0109391861.USD","LU0234570918.USD","LU0683600562.USD","BK4585","LU2237438978.USD","LU0861579265.USD","BK4023","LU0672654240.SGD","LU0320765059.SGD","IE00BD4GTT62.SGD","LU1548497426.USD","LU2317271919.USD","LU0942090050.USD","LU0130517989.USD","LU0980610538.SGD","LU2458330169.SGD","LU1691799644.USD","LU1267930573.SGD","IE00BQXX3D17.EUR","BK4524","LU0061474960.USD","LU0368265418.SGD","LU1201861249.SGD","ADBE","EOG","LU1804176565.USD","LU0211331839.USD","IE00BD4GTV84.USD","IE00BMG7P819.SGD","LU0320765489.SGD","IE00B19Z9505.USD","LU1046421795.USD","LU2210150020.SGD","BK4532","LU1585245621.USD","LU0477156953.USD","LU0057025933.USD","W","LU0719512351.SGD","LU1074936037.SGD","LU0029864427.USD","LU2089283258.USD","LU1623119135.USD","AAMI","LU0106261372.USD","IE00BD4GTW91.USD","LU0310800379.SGD","LU1989763690.USD","LU0342679015.USD","LU1989763427.SGD","LU0310800965.SGD","LU0266512473.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1174266617","title":"Mirum製藥與因塞特醫療公布Zilurgisertib治療進行性骨化性纖維發育不良的關鍵2期研究積極結果","url":"https://stock-news.laohu8.com/highlight/detail?id=1174266617","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1174266617?lang=zh_tw&edition=fundamental","pubTime":"2026-06-15 04:36","pubTimestamp":1781469383,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc. 与因塞特医疗联合宣布，其候选药物Zilurgisertib在治疗进行性骨化性纤维发育不良的关键性2期PROGRESS研究中，取得了积极的顶线结果。与安慰剂相比，接受Zilurgisertib治疗的患者在关键疾病活动指标上表现出显著改善。安全性方面，Zilurgisertib的耐受性普遍良好，观察到的不良事件与先前研究数据一致。此次积极数据标志着在治疗这种罕见、致残性遗传疾病方面的一个重要进展。两家公司正与监管机构讨论下一步开发计划。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4550","BK4532","INCY","BK4588","BK4139","BK4585","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1105034196","title":"Mirum 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(MIRM) 宣布，其针对罕见肝病的研究项目所取得的最新数据，已在2026年欧洲肝病研究学会（EASL）国际肝病大会上正式公布。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636816228","title":"美國研究綜述-CAVA集團、Eagle Materials、Vertiv控股","url":"https://stock-news.laohu8.com/highlight/detail?id=2636816228","media":"路透中文","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636816228?lang=zh_tw&edition=fundamental","pubTime":"2026-05-20 15:08","pubTimestamp":1779260900,"startTime":"0","endTime":"0","summary":"美国研究综述-CAVA集团、Eagle Materials、Vertiv控股路透5月20日 - 周三，华尔街的证券分析师们修订了多家在美国上市公司的评级和目标股价，其中包括CAVA集团、Eagle Materials和Vertiv控股。股票条目按字母顺序排列。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260520:nL4T41X0MS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["EXP","IE0002270589.USD","CAVA","LU2290526834.HKD","LU1035775433.USD","IE00BKPKM429.USD","LU2543165471.USD","JAZZ","VRTL","THC","IONS","IE00B7SZLL34.SGD","LU2108987350.USD","CHRW","LU0098860793.USD","MRNY","UHS","INSM","BRO","LU2249611893.SGD","INCY","BK4585","ALNY","LU0882574055.USD","HALO","BK4139","MIRM","IE00B1XK9C88.USD","BMRN","IE00BN0W2V16.EUR","VRT","LU0868494708.USD","BK4534","LU0417517546.SGD","LU0943347566.SGD","LU0130103400.USD","LU2462157665.USD","IE00BMPRXR70.SGD","HD","MRNX","MRNA","BK4548","DRUG","LU1989772840.SGD","LU0878866978.SGD","VRTX","UTHR","LU2065731478.USD","RLAY","LU2720916845.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636162238","title":"美國研究綜述-CAVA集團、Eagle 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Materials和Vertiv控股。股票条目按字母顺序排列。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260520:nL4S41X0MS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4534","MRNY","THC","LU0942090050.USD","UTHR","LU1303367103.USD","VRT","IE00B19Z9P08.USD","JAZZ","INSM","UHS","IE0002270589.USD","BK4083","IE00B1XK9C88.USD","LU1551013342.USD","HD","IE00BZ1G4Q59.USD","VRTL","MRNA","MIRM","LU2125909916.SGD","DRUG","HALO","LU0061475181.USD","SG9999001440.SGD","LU1929549753.HKD","RLAY","BMRN","IE00B7SZLL34.SGD","VRTX","BK4568","BRO","LU1035775433.USD","EXP","LU0868494617.USD","ALNY","MRNX","BK4209","LU0238689110.USD","IONS","BK4501","LU2362541513.USD","CAVA","CHRW","LU0079474960.USD","LU2456880835.USD","INCY","LU0823414551.USD","LU0878866978.SGD","IE0009355771.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635995937","title":"美國研究綜述-思科、DTE能源、美滿科技","url":"https://stock-news.laohu8.com/highlight/detail?id=2635995937","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635995937?lang=zh_tw&edition=fundamental","pubTime":"2026-05-14 15:25","pubTimestamp":1778743532,"startTime":"0","endTime":"0","summary":"美国研究综述-思科、DTE能源、美满科技路透5月14日 - 周四，华尔街证券分析师调整了多家在美国上市公司的评级和目标股价，其中包括思科、DTE能源和美满科技。股票条目按字母顺序排列。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260514:nL4S41R0NW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["JACK","DT","MAIN","MRVU","AEE","CMP","VSH","ABBV","LU2023251221.USD","MVLL","LU1074936037.SGD","GSHD","CSCO","MRVL","MIRM","NHI","IE00BSNM7G36.USD","HLIO","DOCS","IE00BFTCPJ56.SGD","WEC","KRMN","LU1244550221.USD","LU1084165304.USD","CMS","CAKE","LU0868494708.USD","MOH","LU0054578231.USD","LU1093756168.USD","CSCL","ARMK","LU0234570918.USD","TNGX","XEL","LU0661504455.SGD","DMRA","LU1989764748.USD","USFD","BK4606","LU0444971666.USD","CSCS","WY","EYE","TXRH","DTE","USPH","AMGN","ARVN","STAA"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1104283418","title":"異動解讀 | 藥物研究進展獲分析師看好，Mirum Pharmaceuticals盤中大漲5.26%","url":"https://stock-news.laohu8.com/highlight/detail?id=1104283418","media":"异动解读","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1104283418?lang=zh_tw&edition=fundamental","pubTime":"2026-05-13 21:54","pubTimestamp":1778680466,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.今日盘中股价大涨5.26%，引起了市场的广泛关注。消息面上，该公司近期宣布其用于治疗罕见肝病的药物volixibat在一项中期研究中达到了主要目标，这一积极的临床进展增强了市场对公司研发管线的信心。与此同时，公司也完成了总额6亿美元的可转换优先票据的定价工作，并计划将部分募集资金用于赎回2029年到期的部分票据，以优化其债务结构。这一系列的公司动态共同构成了推动股价上涨的重要因素。","market":"nz","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_cn","symbols":["MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1177923329","title":"Mirum Pharmaceuticals完成6億美元可轉換優先票據定價 並部分贖回2029年到期票據","url":"https://stock-news.laohu8.com/highlight/detail?id=1177923329","media":"美股速递","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1177923329?lang=zh_tw&edition=fundamental","pubTime":"2026-05-13 11:56","pubTimestamp":1778644574,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals宣布完成总额6亿美元的可转换优先票据发行的定价工作。与此同时，公司计划将此次发行所得款项的一部分，用于赎回其2029年到期的部分可转换票据，以实现债务结构的优化。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635840240","title":"熱門話題-Mirum Pharma股價下跌，因宣佈達成6億美元可轉換債券交易","url":"https://stock-news.laohu8.com/highlight/detail?id=2635840240","media":"路透中文","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635840240?lang=zh_tw&edition=fundamental","pubTime":"2026-05-13 04:17","pubTimestamp":1778617058,"startTime":"0","endTime":"0","summary":"由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nL4T41P26H:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632295116","title":"熱門話題-Mirum Pharma股價上漲，因其肝病藥物在臨床試驗中達到主要目標","url":"https://stock-news.laohu8.com/highlight/detail?id=2632295116","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632295116?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 22:54","pubTimestamp":1777906448,"startTime":"0","endTime":"0","summary":"由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260504:nL4T41H15P:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632955455","title":"Mirum公司治療罕見肝病的藥物在中期研究中達到主要目標","url":"https://stock-news.laohu8.com/highlight/detail?id=2632955455","media":"路透中文","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632955455?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 21:08","pubTimestamp":1777900119,"startTime":"0","endTime":"0","summary":"Mirum公司治疗罕见肝病的药物在中期研究中达到主要目标路透5月4日 - Mirum Pharmaceuticals MIRM.O 周一表示，其试验性药物伏利西巴在一项中期研究中达到了主要目标，成功缓解了某类罕见肝病患者的严重瘙痒症状。在主要研究组中，伏利西巴使瘙痒评分较基线降低了2.72分，而安慰剂组仅降低1.08分，由此得出的安慰剂校正获益为1.64分。Mirum公司表示，该结果具有统计学意义。该公司表示，这些结果支持伏利西巴有望成为首款用于治疗PSC患者胆汁淤积性瘙痒的药物。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260504:nL4T41H0Y9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1193143463","title":"Mirum製藥Volixibat安全性特徵與IBAT抑制作用一致 主要表現為胃腸道事件及肝酶升高","url":"https://stock-news.laohu8.com/highlight/detail?id=1193143463","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1193143463?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 20:10","pubTimestamp":1777896611,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals公司公布的研究数据显示，其核心候选药物volixibat的安全性特征与回肠胆汁酸转运蛋白（IBAT）抑制机制高度吻合。临床观察发现，该药物引发的不良反应主要集中于胃肠道范畴，同时伴有肝脏生化参数的可逆性升高。\n值得注意的是，这类安全性表现完全符合IBAT抑制剂类药物已知的作用机理预期。研究人员强调，胃肠道反应与肝酶指标变化均属可控范围，为后续临床开发提供了重要安全性依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1186217776","title":"Mirum Pharmaceuticals預計2027年第一季度公布Volixibat治療PBC的Vantage二期B階段研究頂線數據","url":"https://stock-news.laohu8.com/highlight/detail?id=1186217776","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1186217776?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 20:05","pubTimestamp":1777896314,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals宣布，针对原发性胆汁性胆管炎（PBC）的Volixibat药物Vantage二期B阶段临床研究，预计将于2027年第一季度获得顶线数据结果。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1156368450","title":"Mirum製藥公司計劃2026年夏季與FDA召開Volixibat治療PSC的新藥申請前會議 擬於2026年下半年提交NDA","url":"https://stock-news.laohu8.com/highlight/detail?id=1156368450","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1156368450?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 20:03","pubTimestamp":1777896229,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.宣布，针对Volixibat用于原发性硬化性胆管炎治疗的研发取得重要进展。公司已安排于2026年夏季与美国食品药品监督管理局举行新药申请前会议，此举标志着该药物研发进入关键阶段。根据公司规划，在完成Pre-NDA会议并获取监管机构反馈后，Mirum拟于2026年下半年正式提交Volixibat治疗PSC的新药申请。此次披露的监管时间节点，不仅体现了公司对研发进程的精准把控，也预示着该药物向商业化迈出了实质性步伐。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1101296019","title":"Mirum製藥Volixibt實現瘙癢評分降低2.72分 較安慰劑組優勢達1.64分（P<0.0001）","url":"https://stock-news.laohu8.com/highlight/detail?id=1101296019","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1101296019?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 20:03","pubTimestamp":1777896199,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.旗下药物Volixibat在最新临床试验中展现出显著疗效。数据显示，该药物可使患者瘙痒评分平均降低2.72分，相较于安慰剂组取得的1.08分改善，治疗效果优势达到1.64分。这一差异具有高度统计学意义（P<0.0001），表明Volixibat在缓解瘙痒症状方面具有显著临床价值。\n研究结果进一步验证了Volixibat作为新型治疗方案的潜力。药物通过特异性作用机制靶向疾病根源，为相关患者群体提供了新的治疗选择。此次数据公布为Mirum Pharmaceuticals, Inc.后续的监管申报和商业化进程奠定了重要基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1197260913","title":"Mirum Pharmaceuticals宣佈Volixibat治療原發性硬化性膽管炎的Vistas研究達到主要終點","url":"https://stock-news.laohu8.com/highlight/detail?id=1197260913","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1197260913?lang=zh_tw&edition=fundamental","pubTime":"2026-05-04 20:02","pubTimestamp":1777896160,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals宣布，其药物Volixibat在针对原发性硬化性胆管炎（PSC）患者开展的Vistas研究中，成功达到了预设的主要疗效终点。该重要里程碑标志着公司在肝胆疾病治疗领域的研发取得关键进展。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1189451881","title":"Mirum製藥宣佈Brelovitug治療慢性丁型肝炎的Azure-1研究2B階段達成主要終點","url":"https://stock-news.laohu8.com/highlight/detail?id=1189451881","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1189451881?lang=zh_tw&edition=fundamental","pubTime":"2026-04-27 20:14","pubTimestamp":1777292063,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc. (MIRM) 今日宣布，其针对慢性丁型肝炎病毒（HDV）的创新药物Brelovitug在Azure-1临床研究的2B阶段取得了重大进展，成功达到了预设的主要疗效终点。\n这一关键性成果标志着Brelovitug在治疗这一难治性肝脏疾病的发展道路上迈出了坚实的一步。丁型肝炎是一种严重的病毒性肝炎，目前全球范围内的治疗选择极为有限。Azure-1研究2B阶段的成功，为饱受该疾病困扰的患者带来了新的希望。\n公司表示，将基于此次获得的积极数据，与监管机构进行沟通，并积极推进该药物的后续临床开发计划。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630739603","title":"熱門話題-Mirum Pharma股價上漲，因其丁型肝炎藥物達成主要目標","url":"https://stock-news.laohu8.com/highlight/detail?id=2630739603","media":"路透中文","labels":["shareholding","productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630739603?lang=zh_tw&edition=fundamental","pubTime":"2026-04-27 20:11","pubTimestamp":1777291871,"startTime":"0","endTime":"0","summary":"热门话题-Mirum Pharma股价上涨，因其丁型肝炎药物达成主要目标4月27日 - ** 生物科技公司Mirum Pharmaceuticals MIRM.O的股价在盘前交易中上涨2%，报92.99美元** 该公司表示，其实验性药物brelovitug在一项针对慢性丁型肝炎的中期研究中达到了主要目标。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260427:nL4S41A14O:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1121811592","title":"Mirum製藥完成Livmarli®治療罕見膽汁淤積性肝病三期擴展研究患者招募","url":"https://stock-news.laohu8.com/highlight/detail?id=1121811592","media":"投资观察","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1121811592?lang=zh_tw&edition=fundamental","pubTime":"2026-03-16 20:40","pubTimestamp":1773664821,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.宣布已完成Livmarli®（maralixibat）针对其他罕见胆汁淤积性肝病的三期扩展研究（EXPAND）患者招募工作。\n该研究的顶线数据预计将于2026年第四季度公布。这项进展标志着Mirum在拓展罕见肝病治疗领域迈出关键一步，为患者带来新的希望。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1124176149","title":"Mirum製藥公司：Azure-1與Azure-4預計將於2027年在美國提交BLA申請並上市","url":"https://stock-news.laohu8.com/highlight/detail?id=1124176149","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1124176149?lang=zh_tw&edition=fundamental","pubTime":"2026-03-05 21:04","pubTimestamp":1772715899,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc. 旗下药物Azure-1和Azure-4有望在2027年向美国监管机构提交生物制剂许可申请（BLA），并计划同期实现商业化上市。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":2,"pageCount":1,"totalSize":24,"code":"91000000","status":"200"}]}}