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Alterity Therapeutics Limited

3.44

-0.0100-0.29%

Pre-market: 3.600.2100+6.19%06:28 EDT

Volume:1.37K

Turnover:4.60K

Market Cap:52.33M

PE:-2.34

High:3.44

Open:3.39

Low:3.33

Close:3.45

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Overview Company News Filings

Appendix 4C – Q3 FY25 Quarterly Cash Flow Report

Alterity Therapeutics Presents ATH434-201 Phase 2 Clinical Trial Results at European MSA Symposium

Alterity Therapeutics reports new data from ATH434 Phase 2 trial at AAN meeting

Alterity Therapeutics Presents Encouraging New Data from its ATH434 Phase 2 Trial in Multiple System Atrophy at the American Academy of Neurology Annual Meeting

3 Promising ASX Penny Stocks With Market Caps Over A$20M

Simply Wall St.

Alterity Therapeutics raises A$40M in placement

Alterity Therapeutics Raises A$40.0 million in Placement

Alterity Therapeutics Ltd (ADR) trading halted, news pending

Benchmark Downgrades Alterity Therapeutics to Hold From Speculative Buy

MT Newswires Live

Alterity Therapeutics Is Maintained at Buy by Maxim Group

Alterity Therapeutics (ASX:ATH) shareholder returns have been stellar, earning 260% in 1 year

Simply Wall St.

Sector Update: Health Care Stocks Gain in Afternoon Trading

MT Newswires Live

Top Midday Gainers

Nasdaq Moves Lower; Meta Platforms Posts Strong Sales

Dow Jumps Over 100 Points; Tesla Earnings Miss Views

Alterity Therapeutics Says ATH434 Showed Slowing of Clinical Progression in Phase 2 Multiple System Atrophy Study; Shares Up

MT Newswires Live

Alterity Therapeutics Announces Positive ATH434 Phase 2 Trial Results in Multiple System Atrophy Led By Robust Clinical Efficacy

Alterity Therapeutics Ltd (ADR) trading halted, news pending

Appendix 4C – Q2 FY25 Quarterly Cash Flow Report

Alterity CEO says ‘filled with optimism for 2025’

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Phase 2 data featured in an oral presentation at the American Academy of Neurology Annual Meeting. ATH434-202 open-label trial in advanced MSA completed in March 2025. Cash balance on 31 March 2025 of A$17.96M with an additional A$27.1M raised subsequent to the end of the quarter. David Stamler, M.D., Chief Executive Officer of Alterity, commented, “The third fiscal quarter of 2025 was one of our most successful periods to date for Alterity Therapeutics. The outstanding results from our ATH434 Phase 2 double-blind trial continue to demonstrate the tremendous potential for ATH434 as a disease modifying treatment for MSA and are resonating throughout the medical community. For individuals living with MSA, there is currently no approved therapy to help stabilize or improve their condition, and we believe that ATH434 may be able to chang","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/appendix-4c-q3-fy25-quarterly-113500491.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4178","LU0053671581.USD","LU2125909759.SGD","LU0728928796.USD","LU2125909916.SGD","BK4143","BK4139","LU1815336091.USD","LU2211815571.USD","LU0757428866.USD","ATH.AU","AAN","ATHE","MSA","LU1923622291.USD"],"gpt_icon":0},{"id":"2530470894","title":"Alterity Therapeutics Presents ATH434-201 Phase 2 Clinical Trial Results at European MSA Symposium","url":"https://stock-news.laohu8.com/highlight/detail?id=2530470894","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530470894?lang=en_us&edition=fundamental","pubTime":"2025-04-28 19:35","pubTimestamp":1745840100,"startTime":"0","endTime":"0","summary":"MELBOURNE, Australia and SAN FRANCISCO, April 28, 2025  -- Alterity Therapeutics  , a biotechnology company dedicated to developing disease modifying treatments for neurodegenerative diseases, today announced that David Stamler, M.D., Chief Executive Officer presented the ATH434-201 Phase 2 clinical trial results at the annual MSA Research Symposium hosted by University College London, Institute of Neurology in partnership with the MSA Trust of the U.K.“We were honoured to be selected to present the recent data from our double-blind Phase 2 trial,” said, Dr. Stamler. “The Symposium brought together prominent clinicians and researchers from both Europe and the US along with industry scientists, all of whom are focused on increasing their understanding of MSA and advancing new therapies for this aggressive disorder. The strong clinical efficacy data and novel mechanism of ATH434 was well received by this esteemed group of clinicians and academics, as we collectively seek solutions to imp","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/alterity-therapeutics-presents-ath434-201-113500444.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance_au","symbols":["LU1923622291.USD","LU2211815571.USD","LU0728928796.USD","ATHE","BK4139","LU0053671581.USD","LU0757428866.USD","LU1815336091.USD","LU2125909759.SGD","LU2125909916.SGD","ATH.AU","LENZ","BK4143","BK4007","BK7067","MSA"],"gpt_icon":0},{"id":"2526568284","title":"Alterity Therapeutics reports new data from ATH434 Phase 2 trial at AAN meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2526568284","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526568284?lang=en_us&edition=fundamental","pubTime":"2025-04-10 19:45","pubTimestamp":1744285557,"startTime":"0","endTime":"0","summary":"Alterity Therapeutics (ATHE) announced that new presentations related to its Multiple System Atrophy program were delivered at the American Academy...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-reports-new-data-from-ath434-phase-2-trial-at-aan-meeting?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-reports-new-data-from-ath434-phase-2-trial-at-aan-meeting?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4178","BK4007","BK4139","AAN","ATHE","LENZ"],"gpt_icon":0},{"id":"2526550996","title":"Alterity Therapeutics Presents Encouraging New Data from its ATH434 Phase 2 Trial in Multiple System Atrophy at the American Academy of Neurology Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2526550996","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2526550996?lang=en_us&edition=fundamental","pubTime":"2025-04-10 19:35","pubTimestamp":1744284900,"startTime":"0","endTime":"0","summary":"– Clinically Meaningful Efficacy Observed on Multiple Assessments –。– Confirmed Target Engagement with Reduced Iron Signal in MSA Affected Brain Regions –。Type: Oral Presentation Title: Topline Data from a Randomized, Double Blind, Placebo Controlled Phase 2 Study of ATH434 in Multiple System AtrophyPresenter: Daniel Claassen, M.D., M.S., Professor of Neurology at Vanderbilt University Medical CenterSummary: The oral presentation produced additional data on Alterity’s ATH434-201 Phase 2 clinical trial. Overall, the study results support continued advancement of ATH434 for the treatment of MSA. The imaging outcomes in n=61 participants indicate a heterogeneous localization of pathology and evidence that ATH434 reduces the iron signal in MSA affected brain regions. The clinical analysis included 71 patients who had at least one-post baseline UMSARS I assessment. The data showed that on the modified UMSARS I rating scale, ATH434 demonstrated a clinically significant treatment effect versu","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/alterity-therapeutics-presents-encouraging-data-113500434.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2211815571.USD","BK4143","MSA","LENZ","LU2125909759.SGD","AFG","LU2125909916.SGD","BK4107","LU1815336091.USD","BK4117","TUG","LU0728928796.USD","ATHE","BK4139","LU0053671581.USD","BK4007","BK4178","LU0757428866.USD","ATH.AU","LU1923622291.USD","AAN"],"gpt_icon":0},{"id":"2518081994","title":"3 Promising ASX Penny Stocks With Market Caps Over A$20M","url":"https://stock-news.laohu8.com/highlight/detail?id=2518081994","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518081994?lang=en_us&edition=fundamental","pubTime":"2025-03-12 10:05","pubTimestamp":1741745113,"startTime":"0","endTime":"0","summary":"As Australian shares brace for a potential downturn, with the ASX 200 futures indicating a significant drop, investors are keenly observing market movements and their implications. In such volatile times, penny stocks—though an older term—remain relevant as they often represent smaller or emerging companies that could offer value. By focusing on those with strong financials and growth potential, investors might uncover opportunities in these lesser-known stocks.Overview: Alterity Therapeutics Limited is an Australian company focused on researching and developing therapeutic drugs for neurological disorders such as Alzheimer’s, Huntington’s, and Parkinson’s diseases, with a market cap of A$54.91 million.Overview: Magmatic Resources Limited is involved in the development and exploration of mineral properties in Australia, with a market cap of A$21.27 million.Operations: Magmatic Resources Limited has not reported any specific revenue segments.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/3-promising-asx-penny-stocks-020513943.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance_au","symbols":["BK7058","GNG.AU","BK7055","CLX.AU","VMT.AU","EZZ.AU","BK7129","BK7095","BK7506","ATH.AU","BK7021","BK7018","IGL.AU","BK7062","BK7104","XJO.AU","GTN.AU","BK7067","SHA.AU","WAF.AU","BK7045","XKO.AU","ATHE","BK7048","RPL.AU","XAO.AU","BIS.AU","MAG.AU","AX1.AU"],"gpt_icon":0},{"id":"2510785913","title":"Alterity Therapeutics raises A$40M in placement","url":"https://stock-news.laohu8.com/highlight/detail?id=2510785913","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510785913?lang=en_us&edition=fundamental","pubTime":"2025-02-10 20:31","pubTimestamp":1739190660,"startTime":"0","endTime":"0","summary":"Alterity Therapeutics (ATHE) has received binding commitments for a capital raising of A$40M via a two tranche placement of fully paid ordinary sha...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-raises-a40m-in-placement?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-raises-a40m-in-placement?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ATHE","BK4139","LENZ"],"gpt_icon":0},{"id":"2510859697","title":"Alterity Therapeutics Raises A$40.0 million in Placement","url":"https://stock-news.laohu8.com/highlight/detail?id=2510859697","media":"GlobeNewswire","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510859697?lang=en_us&edition=fundamental","pubTime":"2025-02-10 20:25","pubTimestamp":1739190300,"startTime":"0","endTime":"0","summary":"– Funds to be used primarily to advance development of ATH434 in Parkinsonian Disorders – – Capital raising was strongly supported by domestic and international institutional investors – MELBOURNE, Au","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/10/3023336/0/en/Alterity-Therapeutics-Raises-A-40-0-million-in-Placement.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ATHE","LENZ","LU1815336091.USD","LU1923622291.USD","BK4139","BK4143","LU0728928796.USD","LU2125909759.SGD","LU0757428866.USD","LU2125909916.SGD","LU2211815571.USD","MSA","LU0053671581.USD"],"gpt_icon":0},{"id":"2509250420","title":"Alterity Therapeutics Ltd (ADR) trading halted, news pending","url":"https://stock-news.laohu8.com/highlight/detail?id=2509250420","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509250420?lang=en_us&edition=fundamental","pubTime":"2025-02-06 06:35","pubTimestamp":1738794924,"startTime":"0","endTime":"0","summary":"17:30 EST Alterity Therapeutics (ATHE) Ltd (ADR) trading halted, news pending Published first on TheFly – the ultimate source for real-time, market...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-ltd-adr-trading-halted-news-pending-3?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/alterity-therapeutics-ltd-adr-trading-halted-news-pending-3?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","ATHE","LENZ"],"gpt_icon":0},{"id":"2508112043","title":"Benchmark Downgrades Alterity Therapeutics to Hold From Speculative Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2508112043","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508112043?lang=en_us&edition=fundamental","pubTime":"2025-02-03 20:26","pubTimestamp":1738585603,"startTime":"0","endTime":"0","summary":"Benchmark Downgrades Alterity Therapeutics to Hold From Speculative Buy","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ATHE","LENZ"],"gpt_icon":0},{"id":"2507604350","title":"Alterity Therapeutics Is Maintained at Buy by Maxim Group","url":"https://stock-news.laohu8.com/highlight/detail?id=2507604350","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507604350?lang=en_us&edition=fundamental","pubTime":"2025-01-31 07:00","pubTimestamp":1738278000,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ATHE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  January 30, 2025 18:00 ET (23:00 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ATH.AU","ATHE","LENZ"],"gpt_icon":0},{"id":"2507609958","title":"Alterity Therapeutics (ASX:ATH) shareholder returns have been stellar, earning 260% in 1 year","url":"https://stock-news.laohu8.com/highlight/detail?id=2507609958","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507609958?lang=en_us&edition=fundamental","pubTime":"2025-01-31 05:58","pubTimestamp":1738274326,"startTime":"0","endTime":"0","summary":"The most you can lose on any stock  is 100% of your money. But when you pick a company that is really flourishing, you can make more than 100%. For example, the Alterity Therapeutics Limited  share price had more than doubled in just one year - up 260%. Shareholders are also celebrating an even better 500% rise, over the last three months. In contrast, the longer term returns are negative, since the share price is 14% lower than it was three years ago.Since the stock has added AU$48m to its market cap in the past week alone, let's see if underlying performance has been driving long-term returns.We think companies that have neither significant revenues nor profits are pretty high risk. You should be aware that the company needed to issue more shares recently so that it could raise enough money to continue pursuing its business plan. While some such companies do very well over the long term, others become hyped up by promoters before eventually falling back down to earth, and going bankr","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/alterity-therapeutics-asx-ath-shareholder-215846964.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance_au","symbols":["BK7067","ATHE","ATH","ATH.AU","BK4139","LENZ","BK4162"],"gpt_icon":0},{"id":"2507282674","title":"Sector Update: Health Care Stocks Gain in Afternoon Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2507282674","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507282674?lang=en_us&edition=fundamental","pubTime":"2025-01-31 03:07","pubTimestamp":1738264069,"startTime":"0","endTime":"0","summary":"Health care stocks rose Thursday afternoon, with the NYSE Health Care Index adding 1.4% and the Health Care Select Sector SPDR Fund  climbing 1.3%.The iShares Biotechnology ETF  advanced 1.4%.In corporate news, Alterity Therapeutics  shares surged past 51% after the company said its ATH434 lead candidate demonstrated 48% slowing of clinical progression in a phase 2 trial in people with early-stage multiple system atrophy.Tectonic Therapeutic  shares soared 94% after it said a phase 1b trial showed that TX45 improved left ventricular function and pulmonary hemodynamics.Cigna  shares fell 8.1% after it reported a decline in Q4 adjusted earnings, which also missed market expectations.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","IE0002270589.USD","LU0868494617.USD","LU0058720904.USD","BK4585","BK4196","IE00B19Z3581.USD","LU1059921491.USD","IBB","ATHE","LU0289739699.SGD","BK4588","IE00BSNM7G36.USD","TECX","IE00B19Z3B42.SGD","LU1261432733.SGD","XLV","CI","BK4581"],"gpt_icon":0},{"id":"2507809672","title":"Top Midday Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2507809672","media":"MT Newswires","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507809672?lang=en_us&edition=fundamental","pubTime":"2025-01-31 02:45","pubTimestamp":1738262707,"startTime":"0","endTime":"0","summary":"Alpha Modus  Chief Executive William Alessi emphasized Thursday the company's \"strong\" fundamentals and an \"ongoing\" growth strategy amid \"uninformed speculation\" by certain market participants.\"The recent sell-side activity targeting AMOD stock appears to be driven by misconceptions and a lack of understanding about our business and long-term strategy coupled with the 'de-SPAC norm,'\" Alessi said in a company statement.Tectonic Therapeutic  shares surged 109% after the company said Thursday a phase 1b trial showed that a single intravenous dose of TX45 resulted in \"meaningful improvements\" in left ventricular function and pulmonary hemodynamics.Over 4.3 million shares traded intraday versus a daily average of nearly 144,000.Alterity Therapeutics  said Thursday its ATH434 lead candidate demonstrated 48% slowing of clinical progression in a phase 2 clinical trial in patients with early-stage multiple system atrophy.Shares jumped 50% as intraday trading volume catapulted to more than 20.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/top-midday-gainers-184507995.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TECX","ATHE","AMOD","BK4139","BK4023"],"gpt_icon":0},{"id":"2507676186","title":"Nasdaq Moves Lower; 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Shares Up","url":"https://stock-news.laohu8.com/highlight/detail?id=2507629003","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507629003?lang=en_us&edition=fundamental","pubTime":"2025-01-30 22:39","pubTimestamp":1738247954,"startTime":"0","endTime":"0","summary":"Alterity Therapeutics  shares were sharply higher Thursday morning after the company said that its ATH434 lead candidate demonstrated 48% slowing of clinical progression in a phase 2 clinical trial in patients with early-stage multiple system atrophy.The result was achieved at the 50 mg dose at week 52 when compared with placebo, Alterity said.The company also said that ATH434 was well-tolerated, with no reported serious adverse events.Price: 5.48, Change: +2.49, Percent Change: +83.28","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ATHE","BK4139","LENZ"],"gpt_icon":0},{"id":"2507647737","title":"Alterity Therapeutics Announces Positive ATH434 Phase 2 Trial Results in Multiple System Atrophy Led By Robust Clinical Efficacy","url":"https://stock-news.laohu8.com/highlight/detail?id=2507647737","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507647737?lang=en_us&edition=fundamental","pubTime":"2025-01-30 20:35","pubTimestamp":1738240500,"startTime":"0","endTime":"0","summary":"– Clinically Meaningful Benefit Observed at Both ATH434 Doses Studied –。– Achieved Statistical Significance with Up to 48% Slowing of Clinical Progression on UMSARS Rating Scale –。– Key MRI Biomarker Shows Iron Stabilization in MSA Affected Brain Regions –。– ATH434 Demonstrated a Favorable Safety Profile –。– Webcast Held Yesterday with Access to the Recording Below –。“We are thrilled that ATH434 has demonstrated significant slowing of clinical progression and an excellent safety profile in this rare, rapidly progressive disease,” said David Stamler, M.D., Chief Executive Officer of Alterity. “Currently, there are no approved treatments that slow the progression of MSA and these results show that ATH434’s targeted iron engagement may truly have a disease modifying effect. The fact that we achieved statistical significance on the UMSARS is extremely meaningful because it assesses the functional areas affected in MSA and is the endpoint needed to support drug approval by the U.S. Food 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