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Renaissance Technologies Holdings

1,955.18

+5.240.27%

Number of Gainers:56

Number of Losers:39

Number of Flat:1

PE:- -

High:1,962.02

Open:1,950.49

Low:1,950.49

Close:1,950.37

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Incyte to Pay Novartis $280 Million to Resolve Jakafi Royalties Dispute

MT Newswires Live

Top Midday Stories: Qatar Orders 160 Boeing Jets for Over $200 Billion; Super Micro, DataVolt Form $20 Billion Partnership

MT Newswires Live

Why Exelixis Stock Is Skyrocketing Today

Cboe Could Face Limited Index Options Upside on Tariff Shift, Morgan Stanley Says

MT Newswires Live

Dow's 115-Point Drop Led By Losses For Amgen, 3M Stocks

Target Q1 Likely to Miss Estimates Amid Top-line Headwinds, Oppenheimer Says

MT Newswires Live

Novo Nordisk Rises on Weight-Loss News. It's a Huge Deal for This Stock. -- Barrons.com

Unusually active option classes on open May 14th

These Analysts Slash Their Forecasts On UnitedHealth

CBOE Global Markets Shares Down 1.7% After Morgan Stanley Cuts to Underweight From Overweight

THOMSON REUTERS

Nvidia, Advanced Micro Devices Shares up After Cos Announce AI Deals in the Middle East

THOMSON REUTERS

UnitedHealth Group Shares up 2.2% After 17.8% Slump in Prior Session

THOMSON REUTERS

AMD Stock Rises. Buyback News, and More, Boosts AI Chip Maker. -- Barrons.com

Sector Update: Health Care Stocks Rise Premarket Wednesday

MT Newswires Live

J.P. Morgan Remains a Sell on GlaxoSmithKline (GSK)

BUZZ-Advanced Micro Devices jumps, announces new $6 billion share buyback plan

Caterpillar Showcases Machinery That Has Built America for 100 Years in Celebration of Construction

THOMSON REUTERS

AMD announces new $6 billion share buyback plan

AMD Approves $6 Billion Share Repurchase Plan

MT Newswires Live

AMD Announces New $6 Billion Share Repurchase Authorization

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The company expects to report results from pivotal clinical studies evaluating zanzalintinib in treating colorectal cancer and non-clear cell renal cell carcinoma in the second half of 2025. With these near-term potential positive catalysts and continued strength for Cabometyx, I think Exelixis remains a good biotech stock for aggressive investors to buy.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/investing/2025/05/14/why-exelixis-stock-is-skyrocketing-today/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":["BK4548","EXEL","BK4532","BK4585","BK4116","BK4588","BK4139","BK4560","LU2286300806.USD","BK4613","BK4554","BK4607"],"gpt_icon":1},{"id":"2535007978","title":"Cboe Could Face Limited Index Options Upside on Tariff Shift, Morgan Stanley Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2535007978","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535007978?lang=en_us&edition=fundamental","pubTime":"2025-05-14 23:07","pubTimestamp":1747235247,"startTime":"0","endTime":"0","summary":"Cboe Global Markets  could see limited upside to index options volumes following a \"greater than expected\" de-escalation of China tariffs, Morgan Stanley said in a note Wednesday.The investment bank said it had upgraded Cboe earlier amid uncertainty following the \"Liberation Day\" tariff announcement in April, expecting the exchange to benefit from heightened volatility and tail risks.However, Morgan Stanley said the lower tariffs announced over the weekend prompted a shift in view, citing \"lower recession risk\" and fading tail risks tied to extreme trade outcomes. The firm also noted that improving macro conditions could lead to better opportunities elsewhere in capital markets, prompting a shift toward more risk-on investments.It now sees less upside bias to index options volumes and believes there are better opportunities in capital markets names as macro confidence improves.Morgan Stanley double-downgraded Cboe to underweight from overweight and cut its price target to $215 from $25","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0320765646.SGD","LU0971096721.USD","LU2133065610.SGD","BK4504","LU1074936037.SGD","LU1989772840.SGD","BK4588","LU0795875169.SGD","LU1363072403.SGD","LU2347655156.SGD","BK4534","LU2028103732.USD","LU0158827781.USD","BK4112","BK4532","CBOE","LU0106831901.USD","LU0106261372.USD","LU0795875086.SGD","LU1720051108.HKD","LU2023251221.USD","LU0314104364.USD","LU2089284900.SGD","LU1989772923.USD","LU2357305700.SGD","BK4581","LU1162221912.USD","LU1720051017.SGD","IE00BKVL7J92.USD","LU2089283258.USD","LU0098860793.USD","BK4585","LU0158827948.USD","IE00BZ1G4Q59.USD","LU0225283273.USD","LU0912757837.SGD","LU1732800096.USD","LU2111349929.HKD","LU0267386448.USD","LU2271345857.HKD","LU1548497426.USD","LU1732799900.SGD","LU0006306889.USD","BK4127","LU1668664300.SGD","BK4516"],"gpt_icon":0},{"id":"2535204079","title":"Dow's 115-Point Drop Led By Losses For Amgen, 3M Stocks","url":"https://stock-news.laohu8.com/highlight/detail?id=2535204079","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535204079?lang=en_us&edition=fundamental","pubTime":"2025-05-14 23:05","pubTimestamp":1747235100,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.The Dow Jones Industrial Average is falling Wednesday morning with shares of Amgen and 3M delivering the stiffest headwinds for the blue-chip average.The Dow  was most recently trading 115 points lower , as shares of Amgen  and 3M  have contributed to the index's intraday decline.Amgen's shares have declined $7.10, or 2.6%, while those of 3M have fallen $3.56, or 2.4%, combining for an approximately 66-point drag on the Dow.Merck , Johnson & Johnson , and Sherwin-Williams Co.  are also contributing significantly to the decline.A $1 move in any of the Dow's 30 components results in a 6.15-point swing.Data source: Dow Jones Market Data, FactSet. Data compiled May 14, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DOG","IE00BJT1NW94.SGD","DJX","LU2430703095.HKD","BK4550","MYMmain","LU1506573853.SGD","LU1929549753.HKD","BK4532","BK4206","DXD","JNJ","IE00BBT3K403.USD","LU0345769128.USD","UDOW","LU0320765992.SGD","LU1718418525.SGD","SHW","LU1778281490.HKD","LU0912757837.SGD","LU0795875086.SGD","LU1291159041.SGD","LU1983299246.USD","LU0234572021.USD","AMGN","BK4599","LU0006306889.USD","BK4559","LU0266013472.USD","LU0861579265.USD","IE00BSNM7G36.USD","MMM","IE00B4R5TH58.HKD","LU0122379950.USD","LU1023059063.AUD","LU2129689514.USD","LU1585245621.USD",".DJI","LU1894683348.USD","SG9999014567.USD","SDOW","LU1674673691.USD","LU2505996681.GBP","LU0965509010.AUD","LU2133065610.SGD","DDM","SG9999001176.SGD","SG9999001176.USD","LU1934455194.USD"],"gpt_icon":1},{"id":"2535607668","title":"Target Q1 Likely to Miss Estimates Amid Top-line Headwinds, Oppenheimer Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2535607668","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535607668?lang=en_us&edition=fundamental","pubTime":"2025-05-14 22:40","pubTimestamp":1747233656,"startTime":"0","endTime":"0","summary":"Target (TGT) Q1 results are likely to miss consensus estimates amid top-line headwinds and expense pressures, Oppenheimer said in a Wednesday research report.The brokerage lowered its 2025 projections","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["OPY","BK4504","LU1244550221.USD","LU2237443978.SGD","LU0310799852.SGD","LU0052756011.USD","LU1267930227.SGD","BK4155","BK4532","LU1267930490.SGD","LU1244550494.USD","BK4114","LU0211328371.USD","BK4597","BK4596","LU2237443622.USD","BK4585","LU0211327993.USD","LU0823411888.USD","LU2237443549.SGD","LU2237443382.USD","LU0128525689.USD","LU0310800965.SGD","BK4533","BK4588","BK4127","LU1244550577.SGD"],"gpt_icon":0},{"id":"2535075446","title":"Novo Nordisk Rises on Weight-Loss News. It's a Huge Deal for This Stock. -- Barrons.com","url":"https://stock-news.laohu8.com/highlight/detail?id=2535075446","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535075446?lang=en_us&edition=fundamental","pubTime":"2025-05-14 22:28","pubTimestamp":1747232880,"startTime":"0","endTime":"0","summary":"Septerna stock went through the roof after the biotech said it had landed a $2.2 billion deal to develop oral weight-loss treatments alongside Novo Nordisk.U.S.-listed shares of Novo Nordisk, the maker of Ozempic and Wegovy, climbed 1.7% to $66.51 in early trading. Septerna stock was 53% higher at $10.30. The benchmark S&P 500 was up 0.3%.Under the terms of the deal, Septerna is eligible to receive roughly $2.2 billion through a combination of upfront and milestone payments. The biotech is also entitled to royalties on global sales of marketed products.The partners aim to develop small-molecule therapies for G protein-coupled receptors, which sit on the surface of cells and transmit signals to intracellular proteins. These include GLP-1, GIP, and glucagon receptors, which are common targets of obesity drugs.Novo and Septerna said they plan to launch four development programs for potential small-molecule therapies directed at one or more GPCR targets.Novo and its peers are setting their","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014880.SGD","SG9999015986.USD","BK4588","LU0109394709.USD","LU0354030438.USD","LU1868837300.USD","LU2237443549.SGD","LU1720051017.SGD","BK4007","LU2461242641.AUD","SGXZ51526630.SGD","BK4581","LU2023250504.SGD","LU2237438978.USD","LU2112291526.USD","LU2491050154.USD","LU1720051108.HKD","SG9999014898.SGD","LU2471134952.CNY","IE00BJLML261.HKD","SG9999018857.SGD","LU1023059063.AUD","LU1989771016.USD","LU0786609619.USD","LU1127390331.HKD","LU1548497426.USD","LU1551013425.SGD","LU1917777945.USD","LU0256863902.USD","LU2357305700.SGD","NVO","LU0471298777.SGD","SEPN","LU2361044949.HKD","LU1868836914.USD","LU1069344957.HKD","LU2361045086.USD","LU1061106388.HKD","BK4516","IE0004445239.USD","LU1623119135.USD","SG9999001176.USD","LU2552382132.HKD","BK4532","LU0640476718.USD","LU0097036916.USD","LU1868836591.USD","LU0096364046.USD","SG9999014914.USD"],"gpt_icon":1},{"id":"2535208260","title":"Unusually active option classes on open May 14th","url":"https://stock-news.laohu8.com/highlight/detail?id=2535208260","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2535208260?lang=en_us&edition=fundamental","pubTime":"2025-05-14 21:40","pubTimestamp":1747230019,"startTime":"0","endTime":"0","summary":"Unusual total active option classes on open include: GRANITESHARES 2X LONG AMD DAILY ETF (AMDL), Foot Locker (FL), BigBearai Holdings (BBAI), 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Shares of Septerna were up past 68% while Novo Nordisk stock was over 2% higher pre-bell.GSK  has agreed to acquire Boston Pharmaceuticals' investigational steatotic liver disease treatment efimosfermin alfa for up to $2 billion in cash, the companies said. GSK shares were up over 1% premarket.Scholar Rock  shares were up 0.9% even after the company reported a wider Q1 net loss.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN","SRRK","GSK.UK","GSK","IBB","BK4139","BK4581","IE00BZ1G4Q59.USD","BK4007","BK4585","NVO","XLV","LU0154236417.USD","IE00BKVL7J92.USD","LU1093756168.USD","BK7104","NVO.AU","BK4599","LU1093756325.SGD","LU1829250122.USD","BK4588","BK4532"],"gpt_icon":1},{"id":"2535220460","title":"J.P. 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This new authorization adds to the remaining balance of approximately $4 billion from its existing share repurchase program, increasing the total current repurchase authority to approximately $10 billion.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. AMD - Advanced Micro Devices Inc. published the original content used to generate this news brief via GlobeNewswire  on May 14, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"1bf4ea3a348b5c26f9213b92224d1aa0","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250514:nNDL8FPnJk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1880398554.USD","BK4534","IE00BMPRXR70.SGD","LU0056508442.USD","LU0109392836.USD","LU1303367103.USD","LU0127658192.USD","BK4575","IE00B5949003.HKD","BK4566","LU1803068979.SGD","BK4614","LU2264538146.SGD","LU0642271901.SGD","BK4532","LU1852331112.SGD","LU1316542783.SGD","IE0004445239.USD","LU0823421333.USD","IE00BGHQF748.EUR","LU0719512351.SGD","LU1923623000.USD","NDAQ","LU1242518931.SGD","LU2458330243.SGD","LU0081259029.USD","BK4554","LU2360106780.USD","LU0979878070.USD","AMD","BK4588","LU1988902786.USD","BK4112","IE00BKPKM429.USD","BK4141","LU1951198990.SGD","IE0009356076.USD","BK4573","BK4512","LU0082616367.USD","LU0823434583.USD","LU1989764664.SGD","LU1242518857.USD","LU1880398471.USD","BK4605","IE00B64PRP62.GBP","LU0390134368.USD","LU0889565833.HKD","LU2458330169.SGD","BK4543"],"gpt_icon":1}],"pageSize":20,"totalPage":62,"pageCount":10,"totalSize":1221,"code":"91000000","status":"200"}]}}