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Celcuity Inc

102.25

-0.3600-0.35%

Post-market: 102.250.00000.00%19:06 EST

Volume:351.02K

Turnover:35.81M

Market Cap:4.73B

PE:-27.85

High:103.09

Open:102.27

Low:101.47

Close:102.61

52wk High:112.64

52wk Low:7.58

Shares:46.27M

Float Shares:22.54M

Volume Ratio:0.32

T/O Rate:1.56%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.6721

EPS(LYR):-2.8335

ROE:-122.04%

ROA:-26.60%

PB:40.45

PE(LYR):-36.09

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Overview Company News Filings

Did Gedatolisib’s Phase 3 PFS and Tolerability Data Just Shift Celcuity’s (CELC) Investment Narrative?

Simply Wall St.

Celcuity Reports Positive Phase 3 Results for Gedatolisib in Advanced Breast Cancer Trial

Celcuity Presents Updated Results From the Pik3CA Wild-Type Cohort of the Phase 3 Viktoria-1 Trial at the 2025 San Antonio Breast Cancer Symposium

THOMSON REUTERS

Is Celcuity’s Huge 2025 Rally Justified by Its Long Term Cash Flow Potential?

Simply Wall St.

Celcuity Inc. Director Richard E. Buller Reports Sale of Common Shares

Muling, Heilongjiang: Flax Weaving a Prosperous Industry

Celcuity Is Maintained at Buy by Jefferies

U.S. RESEARCH ROUNDUP- Green Brick Partners, Pultegroup, Toll Brothers

Celcuity Announces Updated Phase 3 VIKTORIA-1 Trial Results for Gedatolisib in HR+/HER2- Advanced Breast Cancer

Celcuity Inc. to Present at Evercore Healthcare Conference

Celcuity Inc. Director David Dalvey Reports Sale of Common Shares

Celcuity Director Richard E. Buller Reports Disposal of Common Shares

Biotech Reawakens: Policy Clarity, Breakthrough Data and a Surge in M&A

Celcuity Q3 Adjusted EPS USD -0.78 Vs. IBES Estimate USD -1.02

Celcuity Initiated at Outperform by Wolfe Research

Celcuity initiated with an Outperform at Wolfe Research

Celcuity Announces Completion of Submission of Its New Drug Application to the U.S. FDA for Gedatolisib in Hr+/Her2-/Pik3CA Wild-Type Advanced Breast Cancer

THOMSON REUTERS

Celcuity Submits New Drug Application to FDA for Gedatolisib in Advanced Breast Cancer

Celcuity Shares Fall After HC Wainwright Downgrade

MT Newswires Live

BUZZ-Celcuity dips as H.C. Wainwright downgrades to 'neutral'

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Gedatolisib’s Phase 3 PFS and Tolerability Data Just Shift Celcuity’s (CELC) Investment Narrative?","url":"https://stock-news.laohu8.com/highlight/detail?id=2591262060","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591262060?lang=en_us&edition=fundamental","pubTime":"2025-12-16 03:24","pubTimestamp":1765826696,"startTime":"0","endTime":"0","summary":"Celcuity Inc. recently reported updated Phase 3 VIKTORIA-1 results for its PAM inhibitor gedatolisib in HR+/HER2-, PIK3CA wild-type advanced breast cancer, highlighting substantial progression-free survival benefits over fulvestrant in multiple patient sub-groups and geographies.\nAn interesting feature of the data is the combination of extended progression-free survival with stable glucose levels and manageable stomatitis, underscoring a differentiated tolerability profile versus many...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-celc/celcuity/news/did-gedatolisibs-phase-3-pfs-and-tolerability-data-just-shif","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-celc/celcuity/news/did-gedatolisibs-phase-3-pfs-and-tolerability-data-just-shif","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["CELC","BK4211","BK4139","BK4195","PFS"],"gpt_icon":0},{"id":"2590546894","title":"Celcuity Reports Positive Phase 3 Results for Gedatolisib in Advanced Breast Cancer Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2590546894","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590546894?lang=en_us&edition=fundamental","pubTime":"2025-12-12 03:35","pubTimestamp":1765481714,"startTime":"0","endTime":"0","summary":"Celcuity Inc., a clinical-stage biotechnology company, announced updated results from the randomized, Phase 3 VIKTORIA-1 trial evaluating gedatolisib, a pan-PI3K and mTORC1/2 inhibitor, in adults with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative , PIK3CA wild-type advanced breast cancer. The data were presented at the 2025 San Antonio Breast Cancer Symposium. Results showed that, for patients whose time to progression on prior therapy exceeded 18 months, the median progression-free survival  was 12.4 months for the gedatolisib triplet , 10.0 months for the gedatolisib doublet , and 1.9 months for fulvestrant alone. Among patients in the U.S., Canada, Western Europe, and Asia Pacific, the median PFS was 16.6 months with the triplet regimen and 7.1 months with the doublet, compared to 1.9 months for fulvestrant. Measures to mitigate stomatitis were generally effective, with most patients experiencing resolution to a lower grade within two weeks.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251211:nNDL25pc6L:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210149790.SGD","SG9999014039.USD","LU0314104364.USD","NDAQ","BK4588","BK4139","CELC","BK4112","LU2210150020.SGD","IE00B3QW5Z07.USD","SG9999014005.SGD","SG9999014021.USD","IE00BGHQF748.EUR","IE00BKPKM429.USD","IE00B64PRP62.GBP","SG9999014013.SGD","BK4585","LU2095319765.USD"],"gpt_icon":0},{"id":"2590546882","title":"Celcuity Presents Updated Results From the Pik3CA Wild-Type Cohort of the Phase 3 Viktoria-1 Trial at the 2025 San Antonio Breast Cancer Symposium","url":"https://stock-news.laohu8.com/highlight/detail?id=2590546882","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590546882?lang=en_us&edition=fundamental","pubTime":"2025-12-12 03:35","pubTimestamp":1765481700,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251211:nTUA6FRZ0N:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2590627195","title":"Is Celcuity’s Huge 2025 Rally Justified by Its Long Term Cash Flow Potential?","url":"https://stock-news.laohu8.com/highlight/detail?id=2590627195","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590627195?lang=en_us&edition=fundamental","pubTime":"2025-12-11 12:50","pubTimestamp":1765428638,"startTime":"0","endTime":"0","summary":"Wondering if Celcuity at around $101 a share is still a smart buy after its huge run, or if you are late to the party? This breakdown will help you decide whether the current price matches the underlying value.\nThe stock has climbed 1.8% over the last week, 32.8% in the last month, and an eye catching 675.6% year to date. Its 1 year gain of 692.5% and 3 year return of 881.0% show just how dramatically market expectations have shifted.\nRecent news flow around Celcuity has centered on growing...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-celc/celcuity/news/is-celcuitys-huge-2025-rally-justified-by-its-long-term-cash","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-celc/celcuity/news/is-celcuitys-huge-2025-rally-justified-by-its-long-term-cash","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["DCF","BK4139","CELC"],"gpt_icon":0},{"id":"2590324550","title":"Celcuity Inc. Director Richard E. Buller Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2590324550","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2590324550?lang=en_us&edition=fundamental","pubTime":"2025-12-10 05:24","pubTimestamp":1765315447,"startTime":"0","endTime":"0","summary":"Richard E. Buller, Director of Celcuity Inc., reported a disposal of common shares of Celcuity Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Celcuity Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 09, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nNDLb7Pvlq:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Celcuity Inc. Director Richard E. Buller Reports Sale of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"1119526407","title":"Muling, Heilongjiang: Flax Weaving a Prosperous Industry","url":"https://stock-news.laohu8.com/highlight/detail?id=1119526407","media":"Deep News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1119526407?lang=en_us&edition=fundamental","pubTime":"2025-12-08 07:30","pubTimestamp":1765150245,"startTime":"0","endTime":"0","summary":"Workers at a flax textile company in Muling City, Heilongjiang Province, are busy with production. Since October, Heilongjiang Hongdoushan Flax Textile Co., Ltd. in Muling has been operating at full...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","CELC"],"gpt_icon":0},{"id":"2588370470","title":"Celcuity Is Maintained at Buy by Jefferies","url":"https://stock-news.laohu8.com/highlight/detail?id=2588370470","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588370470?lang=en_us&edition=fundamental","pubTime":"2025-12-02 19:52","pubTimestamp":1764676320,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/CELC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 02, 2025 06:52 ET (11:52 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2588708783","title":"U.S. RESEARCH ROUNDUP- Green Brick Partners, Pultegroup, Toll Brothers","url":"https://stock-news.laohu8.com/highlight/detail?id=2588708783","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2588708783?lang=en_us&edition=fundamental","pubTime":"2025-12-02 15:06","pubTimestamp":1764659172,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP- Green Brick Partners, Pultegroup, Toll BrothersDec 2 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, includ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251202:nL8N3X8089:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MRP","BK4096","CRL","LU1868837300.USD","DFH","MDB","SDHC","LU1064131342.USD","GRBK","TKO","LU0432979614.USD","LU0757428866.USD","KBH","DE","ICFI","LU0456855351.SGD","LU2112291526.USD","ROK","LU1917777945.USD","LU2211817866.USD","LU0345770308.USD","ACAD","NVR","TOL","ULTA","LU2108987350.USD","LU1057294990.SGD","LU0079474960.USD","CF","PHM","FWONA","LU0980610538.SGD","FTRE","BV","LU1988902786.USD","LU0211331839.USD","BK4120","DHI","EPR","LU0823417737.USD","IE0004445239.USD","LEN","LU2211815571.USD","IQV","FWONK","EOLS","BK4123","CELC","LU0882574139.USD"],"gpt_icon":1},{"id":"2586260920","title":"Celcuity Announces Updated Phase 3 VIKTORIA-1 Trial Results for Gedatolisib in HR+/HER2- Advanced Breast Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2586260920","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2586260920?lang=en_us&edition=fundamental","pubTime":"2025-11-27 05:05","pubTimestamp":1764191120,"startTime":"0","endTime":"0","summary":"Celcuity Inc. announced that updated data from the PIK3CA wild-type cohort of its Phase 3 VIKTORIA-1 clinical trial will be presented at the 2025 San Antonio Breast Cancer Symposium , scheduled for December 9-12, 2025. The presentation will cover additional sub-group efficacy analyses and safety data regarding gedatolisib, a multi-target PI3K/AKT/mTOR inhibitor, in combination with fulvestrant with or without palbociclib for the second-line treatment of patients with HR+/HER2-/PIK3CA-wild type advanced breast cancer. The abstract is currently available on the SABCS website.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Celcuity Inc. published the original content used to generate this news brief via GlobeNewswire  on November 26, 2025","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251126:nNDL5psnbD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210149790.SGD","IE00B64PRP62.GBP","LU0314104364.USD","CELC","LU2210150020.SGD","NDAQ","IE00BKPKM429.USD","IE00B3QW5Z07.USD","LU2095319765.USD","IE00BGHQF748.EUR","BK4139","BK4585","BK4112","BK4588"],"gpt_icon":0},{"id":"2586251908","title":"Celcuity Inc. to Present at Evercore Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2586251908","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2586251908?lang=en_us&edition=fundamental","pubTime":"2025-11-26 20:05","pubTimestamp":1764158709,"startTime":"0","endTime":"0","summary":"Celcuity Inc. will participate in the 8th Annual Evercore Healthcare Conference in Miami, Florida, taking place from December 2-4, 2025. Brian Sullivan, Chief Executive Officer and Co-founder of Celcuity, is scheduled for a fireside chat at 7:30 a.m. ET on Wednesday, December 3, 2025. A live webcast of the event will be available online.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Celcuity Inc. published the original content used to generate this news brief via GlobeNewswire  on November 26, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251126:nNDL2L0RpG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NDAQ","CELC","IE00B64PRP62.GBP","LU2210150020.SGD","LU2210149790.SGD","LU0314104364.USD","BK4585","IE00BGHQF748.EUR","BK4588","BK4139","BK4112","IE00BKPKM429.USD","LU2095319765.USD","IE00B3QW5Z07.USD"],"gpt_icon":0},{"id":"2586490666","title":"Celcuity Inc. Director David Dalvey Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2586490666","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2586490666?lang=en_us&edition=fundamental","pubTime":"2025-11-25 05:07","pubTimestamp":1764018451,"startTime":"0","endTime":"0","summary":"David Dalvey, Director, reported a disposal of common shares of Celcuity Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Celcuity Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on November 24, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251124:nNDL8vqYNr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Celcuity Inc. Director David Dalvey Reports Sale of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","CELC"],"gpt_icon":0},{"id":"2585912501","title":"Celcuity Director Richard E. Buller Reports Disposal of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2585912501","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2585912501?lang=en_us&edition=fundamental","pubTime":"2025-11-22 05:14","pubTimestamp":1763759698,"startTime":"0","endTime":"0","summary":"Richard E. Buller, Director, reported a disposal of common shares of Celcuity Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Celcuity Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on November 21, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251121:nNDL5XrFnM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Celcuity Director Richard E. Buller Reports Disposal of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2585167595","title":"Biotech Reawakens: Policy Clarity, Breakthrough Data and a Surge in M&A","url":"https://stock-news.laohu8.com/highlight/detail?id=2585167595","media":"LiveWire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2585167595?lang=en_us&edition=fundamental","pubTime":"2025-11-21 10:52","pubTimestamp":1763693545,"startTime":"0","endTime":"0","summary":"Sentiment toward pharmaceuticals—both emerging biotech and large-cap pharma—has shifted meaningfully since we last wrote at the end of FY25. Concerns around US tariff risk and “Most Favoured Nation”  pricing dominated headlines in April, but these issues have since been largely neutralised. As policy uncertainty has cleared, investors have returned their focus to fundamentals.From 30 June to 31 October 2025, the S&P Biotech Index rose more than 30%. Over the same period, HB Biotechnology portfolios delivered a 63% return, driven by multiple outstanding clinical readouts and two strategic takeovers of portfolio companies.Despite this global strength, the ASX healthcare sector has lagged , led by the ongoing weakness in ASX: CSL—once again underscoring the need for a global, diversified approach to healthcare investing.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"livewire_stock","url":"https://www.livewiremarkets.com/wires/biotech-reawakens-policy-clarity-breakthrough-data-and-a-surge-in-m-a","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.livewiremarkets.com/wires/biotech-reawakens-policy-clarity-breakthrough-data-and-a-surge-in-m-a","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"livewire_stock","symbols":["MNQmain","SQQQ","IE00B19Z3B42.SGD","LU0985320562.USD","LU1116320901.HKD","NVS","QID","SG9999014559.SGD","LU0098860793.USD","NVIW.SI","SGXZ57979304.SGD","LU2023250504.SGD","REPL","VRNA","BK4559","BK4532","LU0265550359.USD","PSQ","IE000M9KFDE8.USD","LU1037948897.HKD","LU1934455194.USD","USAW.SI","LU2324357040.USD","LU1934455277.USD","LU0861579265.USD","VIGL","TQQQ","RNA","MRK","LU0289739699.SGD","PFE","TSYW.SI","LU1929549753.HKD","IE00BN8TJ469.HKD","LU0238689110.USD","IE00BSNM7G36.USD","BK7067","LU1057294990.SGD","NQmain","CSL.AU","LU2089984988.USD","QLD",".IXIC","LU0265550946.USD","LU1430594728.SGD","USJW.SI","CELC","BK4505","QURE"],"gpt_icon":1},{"id":"2584924129","title":"Celcuity Q3 Adjusted EPS USD -0.78 Vs. IBES Estimate USD -1.02","url":"https://stock-news.laohu8.com/highlight/detail?id=2584924129","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584924129?lang=en_us&edition=fundamental","pubTime":"2025-11-20 01:28","pubTimestamp":1763573294,"startTime":"0","endTime":"0","summary":"Nov 12 (Reuters) - Celcuity Q3 net income USD -43.8 million.:  ((Reuters Investor Briefs; email: reutersinvestor.briefs@thomsonreuters.com))  Source Date/Time = 12-NOV-202521:00:00.403 GMT","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251119:nRSD5Cn4Jv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2584549349","title":"Celcuity Initiated at Outperform by Wolfe Research","url":"https://stock-news.laohu8.com/highlight/detail?id=2584549349","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584549349?lang=en_us&edition=fundamental","pubTime":"2025-11-19 00:53","pubTimestamp":1763484780,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/CELC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 18, 2025 11:53 ET (16:53 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2584560674","title":"Celcuity initiated with an Outperform at Wolfe Research","url":"https://stock-news.laohu8.com/highlight/detail?id=2584560674","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584560674?lang=en_us&edition=fundamental","pubTime":"2025-11-18 05:15","pubTimestamp":1763414115,"startTime":"0","endTime":"0","summary":"Wolfe Research initiated coverage of Celcuity (CELC) with an Outperform rating and $110 price target Fresh off a Phase 3 win for gedatolisib in sec...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/celcuity-initiated-with-an-outperform-at-wolfe-research-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/celcuity-initiated-with-an-outperform-at-wolfe-research-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2584712486","title":"Celcuity Announces Completion of Submission of Its New Drug Application to the U.S. FDA for Gedatolisib in Hr+/Her2-/Pik3CA Wild-Type Advanced Breast Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2584712486","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584712486?lang=en_us&edition=fundamental","pubTime":"2025-11-18 05:05","pubTimestamp":1763413539,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251117:nFWN3WT1UY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","CELC"],"gpt_icon":0},{"id":"2584717656","title":"Celcuity Submits New Drug Application to FDA for Gedatolisib in Advanced Breast Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2584717656","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584717656?lang=en_us&edition=fundamental","pubTime":"2025-11-18 05:05","pubTimestamp":1763413516,"startTime":"0","endTime":"0","summary":"Celcuity Inc. has announced the completion of its New Drug Application  submission to the U.S. Food and Drug Administration  for gedatolisib, a treatment for hormone receptor positive (HR+), HER2-negative, PIK3CA wild-type advanced breast cancer. The NDA was submitted under the FDA's Real-Time Oncology Review  program, which aims to expedite the review process. Gedatolisib previously received Breakthrough Therapy and Fast Track designations based on promising clinical data from the Phase 3 VIKTORIA-1 trial. The application is currently under regulatory review; no final approval has been granted yet. There is no indication that this submission involves funding or participation from organizations other than Celcuity Inc.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251117:nNDL73sFxQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LU2210150020.SGD","BK4112","CELC","LU2095319765.USD","IE00B3QW5Z07.USD","LU0314104364.USD","IE00BGHQF748.EUR","BK4585","IE00B64PRP62.GBP","LU2210149790.SGD","NDAQ","BK4588","IE00BKPKM429.USD"],"gpt_icon":0},{"id":"2584679361","title":"Celcuity Shares Fall After HC Wainwright Downgrade","url":"https://stock-news.laohu8.com/highlight/detail?id=2584679361","media":"MT Newswires Live","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584679361?lang=en_us&edition=fundamental","pubTime":"2025-11-18 03:53","pubTimestamp":1763409233,"startTime":"0","endTime":"0","summary":"Celcuity (CELC) shares fell 1.4% in Monday trading after HC Wainwright downgraded the stock to neutral from buy and raised its price target to $94 from $77.Trading volume was about 935,500 shares, compared with the daily average of 1.1 million.Price: 91.13, Change: -1.55, Percent Change: -1.67","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CELC","BK4139"],"gpt_icon":0},{"id":"2584067653","title":"BUZZ-Celcuity dips as H.C. Wainwright downgrades to 'neutral'","url":"https://stock-news.laohu8.com/highlight/detail?id=2584067653","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584067653?lang=en_us&edition=fundamental","pubTime":"2025-11-18 03:10","pubTimestamp":1763406631,"startTime":"0","endTime":"0","summary":"BUZZ-Celcuity dips as H.C. Wainwright downgrades to 'neutral'** H.C. Wainwright downgrades cancer diagnostics firm Celcuity CELC.O to \"neutral\" from \"buy\"; raises PT to $94 from $77** Brokerage sees the pre-revenue company with a single asset, gedatolisib, and a $4.3 billion valuation as a stock priced for perfection with more downside risk than upside  ** CELC's stock price has appreciated about 608% YTD   ** H.C. Wainwright notes that the FDA has accepted an NDA for gedatolisib in wild-type PIK3CA breast cancer, but risks remain around potential delays, strong competition from large pharma, and weaker-than-expected pricing or adoption **  Shares of Celcuity CELC.O down about 2.96% to $89.94 in afternoon trading** Eight of nine brokerages rate stock \"buy\" or higher, one \"hold\"; median PT is $96.50 — data compiled by LSEG** Including session's moves, CELC stock has risen ~587.1% YTD ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251117:nL6N3WT1EH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CELC","BK4139"],"gpt_icon":0}],"pageSize":20,"totalPage":8,"pageCount":1,"totalSize":144,"code":"91000000","status":"200"}]}}