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Denali Therapeutics Inc.

16.09

-0.5600-3.36%

Volume:657.81K

Turnover:10.68M

Market Cap:2.34B

PE:-6.26

High:16.64

Open:16.53

Low:15.74

Close:16.65

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Overview Company News Filings

Denali Therapeutics price target lowered to $42 from $50 at Oppenheimer

Is Denali Therapeutics Inc. (DNLI) Among Jeff Bezos’ Investments in 2025?

Denali Therapeutics : Oppenheimer Cuts Target Price to $42 From $50

THOMSON REUTERS

Denali Q4 Earnings Beat Estimates, Hunter Syndrome Drug in Focus

Denali Therapeutics (DNLI) Receives a Buy from Stifel Nicolaus

Denali: Entered Equity Distribution Agreement, Pursuant to Which Co May Offer, Sell Shares of Co Common Stock of up to $400 Mln From Time to Time

THOMSON REUTERS

BRIEF-Denali Therapeutics Files For Mixed Shelf Size Not Disclosed - SEC Filing

Denali Therapeutics Inc reports results for the quarter ended December 31 - Earnings Summary

Denali Therapeutics Inc Files for Mixed Shelf; Size Not Disclosed - SEC Filing

THOMSON REUTERS

BRIEF-Denali Therapeutics Q4 Operating Income USD -129.846 Million

Denali Therapeutics Inc - Expects 10%-15% Increase in Cash Operating Expenses for 2025

THOMSON REUTERS

Denali Therapeutics (DNLI) Gets a Buy from Stifel Nicolaus

DNLI Reports Upbeat Longer-Term Data From Hunter Syndrome Study

Denali Therapeutics announces primary analysis of Phase 1/2 study in MPS II

BRIEF-Denali Therapeutics Announces Primary Analysis & Long-Term Follow-Up Of Phase 1/2 Study In Hunter Syndrome With Tividenofusp Alfa

Denali Therapeutics Inc: Long-Term Safety Data Demonstrate That Tividenofusp Alfa Was Generally Well Tolerated

THOMSON REUTERS

Denali Therapeutics: Tividenofusp Alfa U.S. Launch Preparation Ongoing to Deliver Tividenofusp Alfa to Families With Mps Ii in Late 2025 or Early 2026

THOMSON REUTERS

Denali Therapeutics Announces Primary Analysis and Long-Term Follow-up of Phase 1/2 Study in Hunter Syndrome (Mps Ii) With Tividenofusp Alfa

THOMSON REUTERS

Denali Therapeutics Announces Primary Analysis and Long-Term Follow-Up of Phase 1/2 Study in Hunter Syndrome (MPS II) with Tividenofusp Alfa

Denali Therapeutics Announces Upcoming Presentations on Hunter Syndrome (Mps Ii) and Transportvehicle™ Enabled Investigational Therapeutic Tividenofusp Alfa at the 2025 Worldsymposium™

THOMSON REUTERS

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Oppenheimer remains optimistic about the multiple opportunities ahead. Near term, it anticipates imminent filing for DNL310 in Hunter syndrome and suspect a high likelihood for priority review; additional regulatory and clinical updates should further boost investor confidence in the iterability of Denali’s ETV platform as the company is expanding the franchise to address more common diseases. The firm updated its model, lowering the probability of success for DNL343 for ALS while adding DNL126.Discover the Best Stocks and Maximize Your Portfolio:. See what stocks are receiving Strong Buy ratings from top-rated analysts.Filter, analyze, and streamline your search for investment opportunities with  TipRanks’ Stock Screener.Denali Ther","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/denali-therapeutics-price-target-lowered-130044393.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/denali-therapeutics-price-target-lowered-130044393.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["DNLI","OPY","LENZ"],"gpt_icon":0},{"id":"2516651983","title":"Is Denali Therapeutics Inc. 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He has been investing in real estate and companies, staying involved with Amazon and Blue Origin, and becoming close to President-elect Trump. “I’ve actually never worked harder,” he told the New York Times last December.Jeff Bezos has directly invested in at least 108 startups across all industries since 1998, when he was reported to have invested $250,000 into Google. Although he does not publish his returns nor do the firms in which he invests, he has made early bets on several companies that have gone on to launch some of the most high-profile tech IPOs in the recent decade.However, the chances may be in Bezos’ favor, in part because he can combine his economic ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/denali-therapeutics-inc-dnli-among-174915058.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","PSQ","USAW.SI","TQQQ","BK4548","BK4535","QID","SQQQ","QLD","USJW.SI","NVIW.SI","NQmain","DNLI","MNQmain","TSYW.SI",".IXIC"],"gpt_icon":1},{"id":"2516356236","title":"Denali Therapeutics : Oppenheimer Cuts Target Price to $42 From $50","url":"https://stock-news.laohu8.com/highlight/detail?id=2516356236","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516356236?lang=en_us&edition=fundamental","pubTime":"2025-03-03 21:17","pubTimestamp":1741007857,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nAZN3HAGDK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4548","BK4535","DNLI"],"gpt_icon":0},{"id":"2516230551","title":"Denali Q4 Earnings Beat Estimates, Hunter Syndrome Drug in Focus","url":"https://stock-news.laohu8.com/highlight/detail?id=2516230551","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516230551?lang=en_us&edition=fundamental","pubTime":"2025-03-01 02:14","pubTimestamp":1740766440,"startTime":"0","endTime":"0","summary":"Denali Therapeutics DNLI reported a fourth-quarter 2024 loss of 67 cents per share, narrower than the Zacks Consensus Estimate of a loss of 83 cents. 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It plans to engage with the FDA to align on a pathway for accelerated approval of DNL126 based on initial positive phase I/II results demonstrating proof of concep","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/denali-q4-earnings-beat-estimates-181400387.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Denali Q4 Earnings Beat Estimates, Hunter Syndrome Drug in Focus","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["DNLI"],"gpt_icon":0},{"id":"2514214573","title":"Denali Therapeutics (DNLI) Receives a Buy from Stifel Nicolaus","url":"https://stock-news.laohu8.com/highlight/detail?id=2514214573","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514214573?lang=en_us&edition=fundamental","pubTime":"2025-02-28 21:16","pubTimestamp":1740748569,"startTime":"0","endTime":"0","summary":"Stifel Nicolaus analyst Paul Matteis reiterated a Buy rating on Denali Therapeutics (DNLI – Research Report) today and set a price target of $37.00...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/denali-therapeutics-dnli-receives-a-buy-from-stifel-nicolaus?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/denali-therapeutics-dnli-receives-a-buy-from-stifel-nicolaus?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4535","BK4127","BK4548","DNLI","SF"],"gpt_icon":0},{"id":"2514351315","title":"Denali: Entered Equity Distribution Agreement, Pursuant to Which Co May Offer, Sell Shares of Co Common Stock of up to $400 Mln From Time to Time","url":"https://stock-news.laohu8.com/highlight/detail?id=2514351315","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514351315?lang=en_us&edition=fundamental","pubTime":"2025-02-28 06:49","pubTimestamp":1740696561,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nFWN3PI2ED:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4535","DNLI","BK4548","BK4139"],"gpt_icon":0},{"id":"2514482356","title":"BRIEF-Denali Therapeutics Files For Mixed Shelf Size Not Disclosed - 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Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2514735358","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514735358?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:31","pubTimestamp":1740691875,"startTime":"0","endTime":"0","summary":"Denali Therapeutics Inc reports results for the quarter ended December 31 - Earnings SummaryDenali Therapeutics Inc DNLI.OQ reported a quarterly adjusted loss of 67 cents per share for the quarter end","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nL5N3PI387:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DNLI"],"gpt_icon":0},{"id":"2514330740","title":"Denali Therapeutics Inc Files for Mixed Shelf; Size Not Disclosed - 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Denali Therapeutics Q4 basic EPS USD -0.67.\n\nQ4 net income USD -114.753 million\nQ4 operating expenses USD 129.846 million\nQ4 pretax profit USD -114.685 million","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nPLX5C03D4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["DNLI"],"gpt_icon":0},{"id":"2514353805","title":"Denali Therapeutics Inc - Expects 10%-15% Increase in Cash Operating Expenses for 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2514353805","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514353805?lang=en_us&edition=fundamental","pubTime":"2025-02-28 05:01","pubTimestamp":1740690061,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250227:nPLX5C03D4:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4535","DNLI","BK4548"],"gpt_icon":0},{"id":"2510511768","title":"Denali Therapeutics (DNLI) Gets a Buy from Stifel Nicolaus","url":"https://stock-news.laohu8.com/highlight/detail?id=2510511768","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510511768?lang=en_us&edition=fundamental","pubTime":"2025-02-10 20:45","pubTimestamp":1739191527,"startTime":"0","endTime":"0","summary":"Stifel Nicolaus analyst Paul Matteis maintained a Buy rating on Denali Therapeutics (DNLI – Research Report) today and set a price target of $37.00...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/denali-therapeutics-dnli-gets-a-buy-from-stifel-nicolaus?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/denali-therapeutics-dnli-gets-a-buy-from-stifel-nicolaus?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4127","BK4535","BK4548","BK4139","DNLI","SF"],"gpt_icon":0},{"id":"2509801725","title":"DNLI Reports Upbeat Longer-Term Data From Hunter Syndrome Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2509801725","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509801725?lang=en_us&edition=fundamental","pubTime":"2025-02-07 22:54","pubTimestamp":1738940040,"startTime":"0","endTime":"0","summary":"Denali TherapeuticsDNLI reported primary analysis data from an early to mid-stage study of its pipeline candidate, tividenofusp alfa , in 47 patients with Hunter syndrome  over a 24-week treatment period, along with additional long-term follow-up data. DNLI’s wholly-owned program, tividenofusp alfa, is an Enzyme Transport Vehicle-enabled iduronate-2-sulfatase replacement therapy in development for MPS II.Per the additional long-term data readout from the phase I/II study, treatment with tividenofusp alfa resulted in significant and substantial reductions in key disease biomarkers within the central nervous system and peripheral system, bringing them to normal or near-normal levels. Such biomarkers included cerebrospinal fluid and urine heparan sulfate, as well as neurofilament light, a recognized marker of neurodegeneration.Per Denali, such efficacy data suggests the pervasive nature of treatment effects in MPS II patients over the longer term.Shares of DNLI have plunged 28.1% in the 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