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Nuvation Bio, Inc.

5.68

-0.0250-0.44%

Volume:3.39M

Turnover:19.15M

Market Cap:1.95B

PE:-8.87

High:5.92

Open:5.82

Low:5.31

Close:5.70

52wk High:9.75

52wk Low:1.54

Shares:342.83M

Float Shares:231.05M

Volume Ratio:0.65

T/O Rate:1.47%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.6400

EPS(LYR):-2.1131

ROE:-52.49%

ROA:-24.82%

PB:5.97

PE(LYR):-2.69

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News

Nuvation Bio Finalizes Protocol Amendment to Change Safusidenib Study From Mid-Stage to Late-Stage Trial

MT Newswires Live

Nuvation Bio Launches Phase 3 SIGMA Trial of Safusidenib for IDH1-Mutant Glioma

Nuvation Bio Announces Pivotal Global Phase 3 Sigma Trial (G203) for Safusidenib in Idh1-Mutant Glioma

THOMSON REUTERS

Assessing Nuvation Bio (NUVB) Valuation After The Eisai Taletrectinib Partnership Announcement

Simply Wall St.

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Bio Finalizes Protocol Amendment to Change Safusidenib Study From Mid-Stage to Late-Stage Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2610656513","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610656513?lang=en_us&edition=fundamental","pubTime":"2026-02-09 22:04","pubTimestamp":1770645869,"startTime":"0","endTime":"0","summary":"Nuvation Bio  said Monday that it has finalized a protocol amendment to upgrade an ongoing study of its cancer drug, safusidenib, from a mid-stage to a late-stage trial.The expanded registrational study now includes patients with high-risk or high-grade IDH1-mutant astrocytoma who have completed standard care, the company said.Participant enrollment for the trial will increase from 100 to 300 patients across the US, China, and Australia, Nuvation Bio said.The updated protocol also introduces a new group to evaluate the treatment in patients with grade 3 IDH1-mutant oligodendroglioma who have not received chemotherapy or radiation, the company said.Shares of the company were up less than 1% in recent Monday premarket activity.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NUVB","BK4007","SSI"],"gpt_icon":0},{"id":"2610658107","title":"Nuvation Bio Launches Phase 3 SIGMA Trial of Safusidenib for IDH1-Mutant Glioma","url":"https://stock-news.laohu8.com/highlight/detail?id=2610658107","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610658107?lang=en_us&edition=fundamental","pubTime":"2026-02-09 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The SIGMA trial will evaluate the efficacy and safety of safusidenib compared to placebo as maintenance treatment for patients with high-risk or high-grade IDH1-mutant astrocytoma following standard-of-care therapies. The protocol amendment increases enrollment from 100 to 300 patients across the U.S., Australia, and China and broadens eligibility criteria to include grades 2 and 3 IDH1-mutant astrocytoma with high-risk features and grade 4 IDH1-mutant astrocytoma. The study will also include a non-pivotal single-arm cohort for chemotherapy- and radiotherapy-nave patients with grade 3 IDH1-mutant oligodendroglioma. Initial data for the oligodendroglioma cohort are expected in 2027. 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