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PepGen Inc.

1.59

+0.12008.16%

Post-market: 1.610.0200+1.26%18:56 EDT

Volume:294.22K

Turnover:451.50K

Market Cap:51.98M

PE:-0.56

High:1.60

Open:1.52

Low:1.48

Close:1.47

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Overview Company News Filings

PepGen announces CONNECT program updates

PepGen Announces CONNECT Program Updates

All You Need to Know About PepGen (PEPG) Rating Upgrade to Buy

Wedbush Cuts Price Target on PepGen to $8 From $12, Maintains Outperform Rating

MT Newswires Live

PepGen clinical hold likely to be resolved quickly, says Leerink

BofA Securities Downgrades PepGen to Underperform

MT Newswires Live

BofA downgrades PepGen to Underperform after clinical hold

PepGen downgraded to Underperform from Neutral at BofA

PepGen Shares Fall 37.2% on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Trial

THOMSON REUTERS

BUZZ-PepGen falls on clinical hold notice from FDA for mid-stage muscle disorder trial

Corrected-PepGen Shares Fall 18.8% Premarket on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Study (Adds Dropped Word "Premarket")

THOMSON REUTERS

PepGen Receives FDA Clinical Hold in Trial of Potential Duchenne Muscular Dystrophy Treatment; Shares Fall

MT Newswires Live

PepGen Shares Fall 18.8% on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Study

THOMSON REUTERS

BRIEF-Pepgen Announces Clinical Hold In The U.S. On Ind Application To Initiate Connect2-Edo51 Phase 2 Study

PepGen Shares Tumble Premarket as FDA Puts Study on Clinical Hold

FDA issues clinical hold notice to PepGen on IND app for CONNECT2-EDO51 trial

PepGen Inc: Continues to Advance Pgn-Edo51 in Connect1-Edo51, With 10 Mg/Kg Cohort NOW Fully Enrolled

THOMSON REUTERS

PepGen Announces Clinical Hold in the U.S. on Ind Application to Initiate Connect2-Edo51 Phase 2 Study of Pgn-Edo51 for Duchenne Muscular Dystrophy

THOMSON REUTERS

PepGen Announces Clinical Hold in the U.S. on IND Application to Initiate CONNECT2-EDO51 Phase 2 Study of PGN-EDO51 for Duchenne Muscular Dystrophy

PepGen Reports Inducement Grant Under Nasdaq Listing Rule 5635(C)(4) to Newly Appointed Senior Vice President, Clinical Development

THOMSON REUTERS

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In December, the Company announced that it had received a clinical hold notice from the US Food and Drug Administration  regarding its Investigational New Drug application to initiate the CONNECT2 clinical trial in the US, which was previously authorized to proceed by the UK’s Medicines and Healthcare products Regulatory Agency . The Company is working with the FDA to address its questions regarding","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pepgen-announces-connect-program-updates-210500294.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2502238704","title":"All You Need to Know About PepGen (PEPG) Rating Upgrade to Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2502238704","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502238704?lang=en_us&edition=fundamental","pubTime":"2025-01-09 01:00","pubTimestamp":1736355610,"startTime":"0","endTime":"0","summary":"PepGen, Inc.  could be a solid choice for investors given its recent upgrade to a Zacks Rank #2 . This rating change essentially reflects an upward trend in earnings estimates -- one of the most powerful forces impacting stock prices.A company's changing earnings picture is at the core of the Zacks rating. The system tracks the Zacks Consensus Estimate -- the consensus measure of EPS estimates from the sell-side analysts covering the stock -- for the current and following years.Individual investors often find it hard to make decisions based on rating upgrades by Wall Street analysts, since these are mostly driven by subjective factors that are hard to see and measure in real time. In these situations, the Zacks rating system comes in handy because of the power of a changing earnings picture in determining near-term stock price movements.As such, the Zacks rating upgrade for PepGen is essentially a positive comment on its earnings outlook that could have a favorable impact on its stock ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/know-pepgen-pepg-rating-upgrade-170010304.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PEPG"],"gpt_icon":0},{"id":"2492164318","title":"Wedbush Cuts Price Target on PepGen to $8 From $12, Maintains Outperform 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dystrophy, wh...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/pepgen-clinical-hold-likely-to-be-resolved-quickly-says-leerink?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/pepgen-clinical-hold-likely-to-be-resolved-quickly-says-leerink?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2492617568","title":"BofA Securities Downgrades PepGen to Underperform","url":"https://stock-news.laohu8.com/highlight/detail?id=2492617568","media":"MT Newswires 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BofA","url":"https://stock-news.laohu8.com/highlight/detail?id=2492125486","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492125486?lang=en_us&edition=fundamental","pubTime":"2024-12-17 01:05","pubTimestamp":1734368716,"startTime":"0","endTime":"0","summary":"BofA downgraded PepGen (PEPG) to Underperform from Neutral with a $3 price target Published first on TheFly – the ultimate source for real-time, ma...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/pepgen-downgraded-to-underperform-from-neutral-at-bofa?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/pepgen-downgraded-to-underperform-from-neutral-at-bofa?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491694140","title":"PepGen Shares Fall 37.2% on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2491694140","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491694140?lang=en_us&edition=fundamental","pubTime":"2024-12-16 22:32","pubTimestamp":1734359568,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nFWN3NH0GD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491369142","title":"BUZZ-PepGen falls on clinical hold notice from FDA for mid-stage muscle disorder trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2491369142","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491369142?lang=en_us&edition=fundamental","pubTime":"2024-12-16 22:16","pubTimestamp":1734358595,"startTime":"0","endTime":"0","summary":"BUZZ-PepGen falls on clinical hold notice from FDA for mid-stage muscle disorder trial ** Shares of drug developer PepGen PEPG.O fall 27.4% to $3.40 premarket  ** Co receives clinical hold notice from the US FDA regarding its mid-stage muscle disorder trial ** The FDA indicated they will provide an official clinical hold letter to the company within 30 days- PEPG** The study was testing co's experimental drug, PGN-EDO51, in a 25-week clinical trial in patients with Duchenne muscular dystrophy** Duchenne muscular dystrophy is a condition that causes skeletal and heart muscle weakness that quickly gets worse with time** \"We intend to work closely with the FDA to address their questions on our application to initiate CONNECT2 as expeditiously as possible,\" - PEPG ** Co says it continues to test PGN-EDO51 in the mid-stage trial in the 10 mg/kg group ** Up to last close, stock 31.2% YTD    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nL4N3NH10I:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2491713699","title":"Corrected-PepGen Shares Fall 18.8% Premarket on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Study (Adds Dropped Word \"Premarket\")","url":"https://stock-news.laohu8.com/highlight/detail?id=2491713699","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491713699?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:59","pubTimestamp":1734357562,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nL8N3NH0Y3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491699934","title":"PepGen Receives FDA Clinical Hold in Trial of Potential Duchenne Muscular Dystrophy Treatment; Shares Fall","url":"https://stock-news.laohu8.com/highlight/detail?id=2491699934","media":"MT Newswires Live","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491699934?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:53","pubTimestamp":1734357225,"startTime":"0","endTime":"0","summary":"PepGen  said Monday it has received a Food and Drug Administration clinical hold notice for its investigational new drug application to initiate a phase 2 trial of PGN-EDO51, a potential treatment for Duchenne muscular dystrophy.The regulator will send an official clinical hold letter within 30 days, the company said.\"We intend to work closely with the FDA to address their questions on our application to initiate [the trial] as expeditiously as possible,\" said Paul Streck, head of R&D of PepGen.PepGen were down 23% in recent premarket trading.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2491696018","title":"PepGen Shares Fall 18.8% on Receiving Clinical Hold Notice From US FDA for Mid-Stage Muscle Disorder Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696018","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696018?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:45","pubTimestamp":1734356758,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nFWN3NH0G3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491769610","title":"BRIEF-Pepgen Announces Clinical Hold In The U.S. On Ind Application To Initiate Connect2-Edo51 Phase 2 Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2491769610","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491769610?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:38","pubTimestamp":1734356339,"startTime":"0","endTime":"0","summary":"BRIEF-Pepgen Announces Clinical Hold In The U.S. On Ind Application To Initiate Connect2-Edo51 Phase 2 Study Dec 16 (Reuters) - PepGen Inc PEPG.O:PEPGEN ANNOUNCES CLINICAL HOLD IN THE U.S. ON IND APPL","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nTUA6VVXTR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491696357","title":"PepGen Shares Tumble Premarket as FDA Puts Study on Clinical Hold","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696357","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696357?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:29","pubTimestamp":1734355740,"startTime":"0","endTime":"0","summary":"PepGen shares fell sharply in premarket trading Monday after the clinical-stage biotechnology company said the Food and Drug Administration placed a hold on a planned mid-stage study of its PGN-EDO51 drug candidate.PepGen said it has received a clinical-hold notice from the FDA related to the Phase 2 study the neuromuscular genetic disease Duchenne muscular dystrophy, adding that the agency indicated it will provide an official letter within 30 days.Shares of the Boston company, which closed Friday at $4.68, were recently down 25% at $3.53 in premarket trading.According to the FDA's website, subjects can't be given an investigational drug when a proposed study is placed on clinical hold. The agency lists several potential reasons for putting an investigational new drug application on hold, including the possibility that human subjects \"would be exposed to an unreasonable and significant risk of illness or injury,\" or that the application doesn't contain enough information to assess the","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PEPG","BK4139"],"gpt_icon":0},{"id":"2491966756","title":"FDA issues clinical hold notice to PepGen on IND app for CONNECT2-EDO51 trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2491966756","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491966756?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:20","pubTimestamp":1734355258,"startTime":"0","endTime":"0","summary":"PepGen (PEPG) announced that the Company received a clinical hold notice from the U.S. Food and Drug Administration FDA regarding its Investigation...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/fda-issues-clinical-hold-notice-to-pepgen-on-ind-app-for-connect2-edo51-trial?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/fda-issues-clinical-hold-notice-to-pepgen-on-ind-app-for-connect2-edo51-trial?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2491939056","title":"PepGen Inc: Continues to Advance Pgn-Edo51 in Connect1-Edo51, With 10 Mg/Kg Cohort NOW Fully Enrolled","url":"https://stock-news.laohu8.com/highlight/detail?id=2491939056","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491939056?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:00","pubTimestamp":1734354003,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nTUA6VVXTR:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2491469397","title":"PepGen Announces Clinical Hold in the U.S. on Ind Application to Initiate Connect2-Edo51 Phase 2 Study of Pgn-Edo51 for Duchenne Muscular Dystrophy","url":"https://stock-news.laohu8.com/highlight/detail?id=2491469397","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491469397?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:00","pubTimestamp":1734354003,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241216:nTUA6VVXTR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","PEPG"],"gpt_icon":0},{"id":"2491696822","title":"PepGen Announces Clinical Hold in the U.S. on IND Application to Initiate CONNECT2-EDO51 Phase 2 Study of PGN-EDO51 for Duchenne Muscular Dystrophy","url":"https://stock-news.laohu8.com/highlight/detail?id=2491696822","media":"Business Wire","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491696822?lang=en_us&edition=fundamental","pubTime":"2024-12-16 21:00","pubTimestamp":1734354000,"startTime":"0","endTime":"0","summary":"-Company continues to advance PGN-EDO51 in CONNECT1-EDO51, with the 10 mg/kg cohort now fully enrolled-. BOSTON, December 16, 2024----PepGen Inc. , a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurological diseases, today announced that the Company received a clinical hold notice from the U.S. Food and Drug Administration  regarding its Investigational New Drug  application to initiate the CONNECT2-EDO51 clinical trial in patients with Duchenne muscular dystrophy . The FDA indicated they will provide an official clinical hold letter to the Company within 30 days.CONNECT2 is PepGen’s Phase 2 multinational, double-blind placebo-controlled, multiple ascending dose, 25-week clinical trial of PGN-EDO51 in patients with DMD. The study is open in the United Kingdom.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/5CfX8677VEByr0PMNDQ2bA--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/c515608c3ecc07bb254c26ca19230358","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/5CfX8677VEByr0PMNDQ2bA--~B/aD01MTI7dz0xMDI0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/c515608c3ecc07bb254c26ca19230358"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pepgen-announces-clinical-hold-u-130000176.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PEPG","PMO","BK4139"],"gpt_icon":0},{"id":"2485428263","title":"PepGen Reports Inducement Grant Under Nasdaq Listing 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