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Marlborough, Massachusetts-- - Phio Pharmaceuticals Corp.  is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL siRNA gene silencing technology to eliminate cancer. Phio announced today that the Safety Monitoring Committee  recommended dose escalation in Phio's Phase 1b clinical trial  for Phio's lead product candidate, PH-762.Phio's Phase 1b clinical trial is a multi-center, dose-escalating trial designed to evaluate the safety and tolerability of neoadjuvant use of intratumoral PH-762 in cutaneous squamous cell carcinoma, melanoma, or Merkel cell carcinoma. This trial assesses the tumor response and determines the recommended dose for further study of PH-762. In the third cohort of this trial, three patients with cutaneous squamous cell carcinoma were enrolled. 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