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Park Hotels & Resorts Inc.

10.15

-0.1100-1.07%

Post-market: 10.150.00000.00%16:20 EDT

Volume:5.68M

Turnover:58.04M

Market Cap:2.05B

PE:10.05

High:10.43

Open:10.05

Low:10.05

Close:10.26

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Overview Company News Filings

Park Hotels & Resorts Inc reports results for the quarter ended March 31 - Earnings Summary

Spyre Therapeutics Announces Poster Presentations at Digestive Disease Week (DDW) 2025 Including Up to Eight months of Follow-up from an Ongoing Phase 1 Trial of SPY001

Park Hotels & Resorts (PK) Surpasses Q1 FFO and Revenue Estimates

Park Hotels & Resorts Q1 Adjusted FFO, Revenue Decline; Lowers 2025 Outlook

MT Newswires Live

Park Hotels & Resorts: Q1 Earnings Snapshot

Associated Press Finance

Park Hotels & Resorts Q1 FFO $0.46 Beats $0.42 Estimate, Sales $630.00M Beat $610.89M Estimate

BRIEF-Park Hotels & Resorts Q1 Adjusted FFO Per Share USD 0.46

Park Hotels & Resorts Q1 Adjusted Ffo per Share USD 0.46

THOMSON REUTERS

Calendar of U.S. Earnings Expected in the Week Ahead

Preliminary Phase 1b/2 Data for REC-4881 in Familial Adenomatous Polyposis (FAP) Demonstrates Reduced Polyp Burden

Park Hotels & Resorts Inc expected to post earnings of 6 cents a share - Earnings Preview

Agios to Present at the BofA Securities 2025 Health Care Conference on May 14, 2025

EXCLUSIVE: Adial Pharmaceuticals Expands Patent Portfolio With New US Patent For Lead Drug For Alcohol And Opioid Use Disorders

Design Therapeutics Announces Favorable Phase 1 Data for DT-168 Supporting Advancement into Phase 2 Biomarker Trial for Patients with Fuchs Endothelial Corneal Dystrophy

Agios Reports First Quarter 2025 Financial Results and Recent Business Highlights

Park Hotels & Resorts Inc : Bofa Global Research Cuts to Underperform From Neutral; Cuts Price Objective to $11 From $11.50

THOMSON REUTERS

CERo Therapeutics Holdings, Inc. Announces TriStar Centennial Medical Center as a Clinical Trial Site for its Phase 1 Clinical Trial of CER-1236 in Acute Myeloid Leukemia

BofA Securities Downgrades Park Hotels & Resorts to Underperform From Neutral

MT Newswires Live

Larimar Therapeutics Reports First Quarter 2025 Financial Results

Affimed Shows Higher Exposure of AFM24 is Associated with Significantly Higher Response Rates and Progression-Free Survival in Refractory NSCLC Patients at AACR Annual Meeting

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SPY001 pharmacokinetic  data up to eight months continues to support a potential best-in-class profile, including a half-life more than three times that of vedolizumab. SPY001 pharmacodynamic  data up to eight months showed that a single dose of SPY001 resulted in rapid and sustained saturation of α4β7 receptors at expected Phase 2 trough concentrations. Spyre presented results out to eight months of follow up from its SPY001 Phase 1 program.Updated results from our ongoing Phase 1 trial of SPY001, our novel half-life extended α4β7 antibody for the treatment of IBD, continues to show that SPY001 is well tolerated, has a half-life of more than three-fold compared to vedolizumab based on population PK modeling, and sustains target engagement at expected Phase 2 trough concentrations. This longer follow-up data strengthens the potential for SPY001 to demonstrate improved in","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-poster-presentations-120000455.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/spyre-therapeutics-announces-poster-presentations-120000455.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4023","IBD","BK4181","BK4139","PK","PD","LU1169590202.USD","LENZ","BK4007","BK4218","SYRE","LU1169589451.USD"],"gpt_icon":0},{"id":"2533536732","title":"Park Hotels & Resorts (PK) Surpasses Q1 FFO and Revenue Estimates","url":"https://stock-news.laohu8.com/highlight/detail?id=2533536732","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533536732?lang=en_us&edition=fundamental","pubTime":"2025-05-05 19:40","pubTimestamp":1746445203,"startTime":"0","endTime":"0","summary":"Park Hotels & Resorts  came out with quarterly funds from operations  of $0.46 per share, beating the Zacks Consensus Estimate of $0.41 per share. This compares to FFO of $0.52 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an FFO surprise of 12.20%. A quarter ago, it was expected that this company would post FFO of $0.40 per share when it actually produced FFO of $0.39, delivering a surprise of -2.50%.Park Hotels & Resorts , which belongs to the Zacks REIT and Equity Trust - Other industry, posted revenues of $630 million for the quarter ended March 2025, surpassing the Zacks Consensus Estimate by 2.49%. This compares to year-ago revenues of $639 million. The company has topped consensus revenue estimates two times over the last four quarters.Park Hotels & Resorts shares have lost about 27.1% since the beginning of the year versus the S&P 500's decline of -3.3%.While Park Hotels & Resorts has underperformed the market so far t","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/park-hotels-resorts-pk-surpasses-114003996.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PK"],"gpt_icon":0},{"id":"2533583946","title":"Park Hotels & Resorts Q1 Adjusted FFO, Revenue Decline; Lowers 2025 Outlook","url":"https://stock-news.laohu8.com/highlight/detail?id=2533583946","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533583946?lang=en_us&edition=fundamental","pubTime":"2025-05-05 19:32","pubTimestamp":1746444724,"startTime":"0","endTime":"0","summary":"Park Hotels & Resorts  reported Q1 adjusted funds from operations Monday of $0.46 per diluted share, down from $0.52 a year earlier.Analysts polled by FactSet expected Q1 AFFO of $0.22 and Q1 core FFO of $0.42.Revenue for the quarter ended March 31 was $630 million, down from $639 million a year earlier.Analysts surveyed by FactSet expected $614.2 million.For 2025, the real estate investment trust lowered its projection for adjusted  FFO per diluted share to $1.79 to $2.09, from a previous range of $1.90 to $2.20.Analysts polled by FactSet expect 2025 AFFO of $1.13 and and 2025 core FFO of $1.95.Shares of the company were down 0.1% in recent premarket activity.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PK"],"gpt_icon":0},{"id":"2533588036","title":"Park Hotels & Resorts: Q1 Earnings Snapshot","url":"https://stock-news.laohu8.com/highlight/detail?id=2533588036","media":"Associated Press Finance","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533588036?lang=en_us&edition=fundamental","pubTime":"2025-05-05 18:38","pubTimestamp":1746441496,"startTime":"0","endTime":"0","summary":"TYSONS, Va.  — TYSONS, Va.  — Park Hotels & Resorts Inc.  on Monday reported a key measure of profitability in its first quarter. The results surpassed Wall Street expectations.The real estate investment trust, based in Tysons, Virginia, said it had funds from operations of $92 million, or 46 cents per share, in the period.The average estimate of six analysts surveyed by Zacks Investment Research was for funds from operations of 41 cents per share.Funds from operations is a closely watched measure in the REIT industry. It takes net income and adds back items such as depreciation and amortization.The company said it had a loss of $57 million, or 29 cents per share.Park Hotels & Resorts, based in Tysons, Virginia, posted revenue of $630 million in the period, which also topped Street forecasts. Five analysts surveyed by Zacks expected $614.7 million.Park Hotels & Resorts expects full-year funds from operations in the range of $1.79 to $2.09 per share.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/park-hotels-resorts-q1-earnings-103816156.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PK"],"gpt_icon":0},{"id":"2533307301","title":"Park Hotels & Resorts Q1 FFO $0.46 Beats $0.42 Estimate, Sales $630.00M Beat $610.89M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2533307301","media":"Benzinga","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533307301?lang=en_us&edition=fundamental","pubTime":"2025-05-05 18:32","pubTimestamp":1746441147,"startTime":"0","endTime":"0","summary":"Park Hotels &amp; Resorts (NYSE:PK) reported quarterly earnings of $0.46 per share which beat the analyst consensus estimate of $0.42 by 9.52 percent. This is a 11.54 percent decrease over earnings of $0.52 per share from","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/25/05/45189906/park-hotels-resorts-q1-ffo-0-46-beats-0-42-estimate-sales-630-00m-beat-610-89m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PK"],"gpt_icon":0},{"id":"2533130735","title":"BRIEF-Park Hotels & Resorts Q1 Adjusted FFO Per Share USD 0.46","url":"https://stock-news.laohu8.com/highlight/detail?id=2533130735","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533130735?lang=en_us&edition=fundamental","pubTime":"2025-05-05 18:30","pubTimestamp":1746441046,"startTime":"0","endTime":"0","summary":"BRIEF-Park Hotels & Resorts Q1 Adjusted FFO Per Share USD 0.46\n\n\nMay 05 (Reuters) - Park Hotels & Resorts Q1 adjusted EBITDA USD 151 million vs. IBES estimate USD 134 million.\n\nQ1 adjusted revpar USD 177.67\nQ1 EPS USD -0.29 vs. IBES estimate USD 0.06","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250505:nPLX6B8B29:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4181","BK4218","PK"],"gpt_icon":0},{"id":"2533530731","title":"Park Hotels & Resorts Q1 Adjusted Ffo per Share USD 0.46","url":"https://stock-news.laohu8.com/highlight/detail?id=2533530731","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533530731?lang=en_us&edition=fundamental","pubTime":"2025-05-05 18:30","pubTimestamp":1746441001,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250505:nPLX6B8B29:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4181","PK","BK4218"],"gpt_icon":0},{"id":"2533883307","title":"Calendar of U.S. Earnings Expected in the Week Ahead","url":"https://stock-news.laohu8.com/highlight/detail?id=2533883307","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533883307?lang=en_us&edition=fundamental","pubTime":"2025-05-05 18:30","pubTimestamp":1746441000,"startTime":"0","endTime":"0","summary":"Major companies tentatively scheduled to report quarterly earnings in the week ahead, with earnings estimates provided by FactSet Research Systems Inc.·Air Lease Corp                                     1Q       .87    4:05 PM. ·Angel Oak Mtge                                   1Q       .29    7:00 AM. ·Bain Cap Spec Fin                                1Q       .47        AMC. ·BRC Inc Class A                                  1Q      (.02)       AMC. ·Crawford & Co                                   1Q       .18    4:15 PM","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CERT","BRK.A","OCUL","TRUE","CE","VVX","CRGY","BRBR","RLAY","ON","ACEL","AMRC","INSP","CLX","TGTX","CORT","TDUP","EVER","FRPT","PK","TTAM","VNO","NMFC","RLJ","PRAA","ADUS","ACM","IPAR","TBI","ADEA","SIBN","KRC","OGS","UPWK","VTS","MYPS","BSM","BCSF","SNDX","TIMB","MATX","GBDC","VMEO","TCMD","HSIC","GECC","AESI","OPAD","TDW"],"gpt_icon":1},{"id":"2533334128","title":"Preliminary Phase 1b/2 Data for REC-4881 in Familial Adenomatous Polyposis (FAP) Demonstrates Reduced Polyp Burden","url":"https://stock-news.laohu8.com/highlight/detail?id=2533334128","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2533334128?lang=en_us&edition=fundamental","pubTime":"2025-05-05 00:45","pubTimestamp":1746377100,"startTime":"0","endTime":"0","summary":"In the Phase 2 open-label study, REC-4881  led to a median 43% reduction  in polyp burden at the Week 13 assessment at time of data cutoff.Five of six patients (83%) experienced reductions in polyp burden ranging from 31% to 82%, however, one patient showed a substantial increase from baseline.The early safety profile of REC-4881 was generally consistent with that of prior MEK1/2 inhibitors; among 19 patients across Phase 1b and 2, most treatment-related adverse events were Grade 1 or 2, with Grade 3 events in 16% of patients and no Grade ≥4 TRAEs reported to date.Across the combined Phase 1b and ongoing Phase 2 cohorts , REC-4881 demonstrated an early safety profile generally consistent with that of prior MEK1/2 inhibitors. Seventy-nine percent  of patients experienced at least one treatment-related adverse event , the majority of which were Grade 1 or 2 in severity. Grade 3 TRAEs occurred in 16% of patients, with no Grade ≥4 events reported to date. In Phase 1b, the","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/preliminary-phase-1b-2-data-164500686.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4548","BK4181","CPK","REC","BK4539","BK4218","BK4611","BK4197","TRAE","PK","RXRX","BK4609","BK4139"],"gpt_icon":1},{"id":"2532306844","title":"Park Hotels & Resorts Inc  expected to post earnings of 6 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2532306844","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532306844?lang=en_us&edition=fundamental","pubTime":"2025-05-02 21:45","pubTimestamp":1746193506,"startTime":"0","endTime":"0","summary":"Park Hotels & Resorts Inc  expected to post earnings of6cents a share - Earnings Preview Park Hotels & Resorts Inc PK.N, PK is expected to show a fall in quarterly revenue when it reports  results on ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250502:nL8N3RA23V:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PK"],"gpt_icon":0},{"id":"2532106128","title":"Agios to Present at the BofA Securities 2025 Health Care Conference on May 14, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2532106128","media":"GlobeNewswire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532106128?lang=en_us&edition=fundamental","pubTime":"2025-05-02 19:00","pubTimestamp":1746183600,"startTime":"0","endTime":"0","summary":"CAMBRIDGE, Mass., May 02, 2025  -- Agios Pharmaceuticals, Inc. , a leader in cellular metabolism and PK activation pioneering therapies for rare diseases, today announced that its management team is scheduled to present at the BofA Securities 2025 Health Care Conference on Wednesday, May 14, 2025, at 8:00 am PT/11:00 am ET.About AgiosAgios is the pioneering leader in PK activation and is dedicated to developing and delivering transformative therapies for patients living with rare diseases. In theU.S., Agios markets a first-in-class pyruvate kinase  activator for adults with PK deficiency, the first disease-modifying therapy for this rare, lifelong, debilitating hemolytic anemia. Building on the company's deep scientific expertise in classical hematology and leadership in the field of cellular metabolism and rare hematologic diseases, Agios is advancing a robust clinical pipeline of investigational medicines with programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/agios-present-bofa-securities-2025-110000898.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PK","BK4139","BK4218","BK4181","AGIO"],"gpt_icon":0},{"id":"2532074710","title":"EXCLUSIVE: Adial Pharmaceuticals Expands Patent Portfolio With New US Patent For Lead Drug For Alcohol And Opioid Use Disorders","url":"https://stock-news.laohu8.com/highlight/detail?id=2532074710","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532074710?lang=en_us&edition=fundamental","pubTime":"2025-05-01 20:02","pubTimestamp":1746100961,"startTime":"0","endTime":"0","summary":"The United States Patent and Trademark Office  issued patent number 12,274,692 to Adial Pharmaceuticals, Inc.’s  AD04 on Thursday.The patent covers a method of treating alcohol-related diseases and opioid-related disorders using AD04 in genetically identified patients.This newly issued patent strengthens Adial’s intellectual property portfolio by covering the administration of AD04, the company’s investigational drug.Also Read: EXCLUSIVE: After FDA Response, Adial Starts Manufacturing Clinical Supplies For Upcoming Phase 3 Program Of Lead Candidate For Alcohol Use Disorder. The patent claims a method of treating addiction by administering a therapeutically effective amount of AD04 to patients with serotonin-related gene variations.The granted claims include specific genetic profiles associated with treatment efficacy and the corresponding dosing regimens.Specifically for AUD, the patent claims cover a method of treatment for a broad definition of alcohol-related disorders, includingdis","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/exclusive-adial-pharmaceuticals-expands-patent-120241165.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4218","BK4181","BK4007","ADIL","PK"],"gpt_icon":0},{"id":"2532018074","title":"Design Therapeutics Announces Favorable Phase 1 Data for DT-168 Supporting Advancement into Phase 2 Biomarker Trial for Patients with Fuchs Endothelial Corneal Dystrophy","url":"https://stock-news.laohu8.com/highlight/detail?id=2532018074","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532018074?lang=en_us&edition=fundamental","pubTime":"2025-05-01 20:00","pubTimestamp":1746100800,"startTime":"0","endTime":"0","summary":"Phase 2 biomarker trial in FECD patients anticipated to begin in the second half of 2025. CARLSBAD, Calif., May 01, 2025  -- Design Therapeutics, Inc. , a clinical-stage biotechnology company developing treatments for serious degenerative genetic diseases, today announced favorable data from a Phase 1 single- and multiple-ascending dose  trial of DT-168 in healthy volunteers, which will be presented on May 2, 2025 at Eyecelerator @ Park City 2025, an event backed by the American Academy of Ophthalmology highlighting industry advancements and innovative new products disrupting eye care.Based on these findings, Design plans to conduct a Phase 2 biomarker trial of DT-168 to evaluate safety, tolerability, and corneal endothelium biomarkers in patients with FECD. The trial will enroll FECD patients with the TCF4 mutation who are sc","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/design-therapeutics-announces-favorable-phase-120000674.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","LENZ","PK","BK4505","DSGN","BK4007","BK4181","BK4539","BK4218"],"gpt_icon":0},{"id":"2532020582","title":"Agios Reports First Quarter 2025 Financial Results and Recent Business Highlights","url":"https://stock-news.laohu8.com/highlight/detail?id=2532020582","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2532020582?lang=en_us&edition=fundamental","pubTime":"2025-05-01 18:30","pubTimestamp":1746095400,"startTime":"0","endTime":"0","summary":"– U.S. Regulatory Filing Under Active Review for Approval of PYRUKYND  in Thalassemia,with PDUFA Goal Date ofSeptember 7, 2025 –。– Phase 3 RISE UP Study of Mitapivat in Sickle Cell Disease On Track, with Topline Results Expected in Late 2025; Potential U.S. Commercial Launch in 2026 –。– Tebapivat Advancing in Clinical Trials for Lower-Risk Myelodysplastic Syndromes  and Sickle Cell Disease –。– PYRUKYND Net Revenue of $8.7 Million in Q1; Cash, Cash Equivalents and Marketable Securities of $1.4 Billion as of March 31, 2025 –。ThePhase 3 RISE UP studyevaluating mitapivat for the treatment of sickle cell disease patients who are 16 years of age or older continued to progress as anticipated. This 52-week Phase 3 study completed enrollment in October 2024, enrolling more than 200 pat","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/agios-reports-first-quarter-2025-103000986.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["AGIO","PK","BK4139","BK4181","BK4218"],"gpt_icon":0},{"id":"2531092058","title":"Park Hotels & Resorts Inc : Bofa Global Research Cuts to Underperform From Neutral; Cuts Price Objective to $11 From $11.50","url":"https://stock-news.laohu8.com/highlight/detail?id=2531092058","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531092058?lang=en_us&edition=fundamental","pubTime":"2025-04-30 21:44","pubTimestamp":1746020682,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250430:nFWN3R82ZO:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4181","PK","BK4218"],"gpt_icon":0},{"id":"2531203126","title":"CERo Therapeutics Holdings, Inc. Announces TriStar Centennial Medical Center as a Clinical Trial Site for its Phase 1 Clinical Trial of CER-1236 in Acute Myeloid Leukemia","url":"https://stock-news.laohu8.com/highlight/detail?id=2531203126","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531203126?lang=en_us&edition=fundamental","pubTime":"2025-04-30 20:15","pubTimestamp":1746015300,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif., April 30, 2025  -- CERo Therapeutics Holdings, Inc.,   an innovative immunotherapy company seeking to advance the next generation of engineered T cell therapeutics that employ phagocytic mechanisms, announces that TriStar Centennial Medical Center, through Sarah Cannon Research Institute , in Nashville, Tennessee, is a clinical trial site for the Company’s Phase 1 clinical of CER-1236. Collaborating with SCRI to advance cancer research, TriStar Centennial offers innovative clinical research trials for various disease indications. The trial is focused on patients with acute myeloid leukemia , and patient enrollment is underway, with expected dosing of the first patient during the first half of 2025.CERo is an innovative immunotherapy company advancing the development of next generation engineered T cell therapeutics for the treatment of cancer. Its proprietary approach to T cell engineering, which enables it to integrate certain desirable characteristics of ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cero-therapeutics-holdings-inc-announces-121500799.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4181","CERO","BK4218","BK4161","CEROW","CR","BK4139","PK","ORR"],"gpt_icon":0},{"id":"2531368490","title":"BofA Securities Downgrades Park Hotels & Resorts to Underperform From Neutral","url":"https://stock-news.laohu8.com/highlight/detail?id=2531368490","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531368490?lang=en_us&edition=fundamental","pubTime":"2025-04-30 19:39","pubTimestamp":1746013159,"startTime":"0","endTime":"0","summary":"Park Hotels & Resorts (PK) has an average rating of overweight and mean price target of $13.88, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research fro","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PK"],"gpt_icon":0},{"id":"2531039139","title":"Larimar Therapeutics Reports First Quarter 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2531039139","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531039139?lang=en_us&edition=fundamental","pubTime":"2025-04-30 19:00","pubTimestamp":1746010800,"startTime":"0","endTime":"0","summary":"FDA stated as part of a START pilot program meeting that it is open to considering skin FXN concentration as a reasonably likely surrogate endpoint in support of an accelerated approval. BLA seeking accelerated approval planned to be submitted by year-end 2025; global Phase 3 study planned to initiate in mid-2025. Completed dosing in adolescent PK run-in study; topline 50 mg dose data from the OLE study and data from adolescent cohort planned for program update in September 2025. Strong balance sheet of $157.5 million cash, cash equivalents and marketable securities as of March 31, 2025, with projected cash runway into second quarter of 2026. Potential for Accelerated Approval Pathway Based on Skin FXN Concentration","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/larimar-therapeutics-reports-first-quarter-110000276.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LRMR","PK","BK4007","BK4181","LENZ","BK4218","BK4139"],"gpt_icon":0},{"id":"2531759499","title":"Affimed Shows Higher Exposure of AFM24 is Associated with Significantly Higher Response Rates and Progression-Free Survival in Refractory NSCLC Patients at AACR Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2531759499","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2531759499?lang=en_us&edition=fundamental","pubTime":"2025-04-29 22:00","pubTimestamp":1745935200,"startTime":"0","endTime":"0","summary":"An exposure-outcome analysis in 72 patients with refractory non-small cell lung cancer  who received AFM24 at 480 mg weekly demonstrates that higher drug exposure  leads to improved objective response rate  and longer progression free survival   without a negative impact on safety. These findings will be incorporated in future AFM24 trials to further improve efficacy outcomes of patients treated with AFM24. MANNHEIM, Germany, April 29, 2025  -- Affimed N.V. , a clinical-stage immuno-oncology company committed to giving patients back their innate ability to fight cancer, today presented findings on an exposure-outcome analysis of its innate cell engager  AFM24, in patients with advanced or metastatic non-small cell lung cancer  in a poster session at the 2025 Annual Meeting of the American Association for Cancer Research .The analysis is based on post-hoc exposure-response data from 72 NSCLC patients treated with 480 mg of AFM24 monotherapy or a combination of AFM24 with atezolizumab. 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