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uniQure NV

16.37

-0.7500-4.38%

Volume:1.99M

Turnover:32.52M

Market Cap:1.02B

PE:-3.77

High:17.28

Open:17.07

Low:15.90

Close:17.12

52wk High:71.50

52wk Low:7.76

Shares:62.29M

Float Shares:40.64M

Volume Ratio:1.25

T/O Rate:4.90%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-4.3443

EPS(LYR):-4.9242

ROE:-165.27%

ROA:-13.89%

PB:4.46

PE(LYR):-3.32

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Overview Company News Filings

Uniqure NV expected to post a loss of 95 cents a share - Earnings Preview

RBC Capital says Makary comments on uniQure gene therapy approach disappointing

Analysts Offer Insights on Healthcare Companies: Butterfly Network (BFLY) and uniQure (QURE)

Stifel says uniQure ‘understandably’ under pressure on Makary comments

Class Action Lawsuit Targets uniQure NV Investors

Rosen Law Firm Sets April 13 Lead Plaintiff Deadline in uniQure Securities Class Action

Rosen Law Firm urges uniQure investors to act before April 13 lead plaintiff deadline

uniQure Initiated at Peer Perform by Wolfe Research

uniQure initiated with a Peer Perform at Wolfe Research

uniQure NV updated its financial calendar

uniQure to Announce 2025 Financial Results

Class Action Lawsuit Targets uniQure NV Over Alleged Securities Fraud

Investors Sue uniQure NV Over Alleged Misleading Disclosures

uniQure Faces Class Action Over Alleged Misleading Statements on Drug Approval

Assessing uniQure (QURE) Valuation After New Securities Fraud Lawsuit On AMT-130 Disclosures

Simply Wall St.

uniQure Price Target Maintained With a $70.00/Share by HC Wainwright & Co.

How Early AMT-191 Gene Therapy Signals Will Impact uniQure (QURE) Investors

Simply Wall St.

Early uniQure Fabry Trial Shows Lasting Enzyme Boost, Safety Watch

Benzinga_recent_news

uniQure präsentiert neue Phase-I/IIa-Daten zur Gentherapie AMT-191 bei Fabry-Krankheit

uniQure Reports Sustained Enzyme Increases in Phase I/IIa Fabry Disease Gene Therapy Trial

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uniQu...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-butterfly-network-bfly-and-uniqure-qure-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-butterfly-network-bfly-and-uniqure-qure-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0029874061.USD","LU0109394709.USD","BK4585","QURE","BK4139","XBI","BK4082","BK4581","BFLY","LABU","LU0889565916.HKD","BK4137","HCSG","LU0320765992.SGD","LU0128526141.USD","XLV","BK4588"],"gpt_icon":0},{"id":"2614024172","title":"Stifel says uniQure ‘understandably’ under pressure on Makary comments","url":"https://stock-news.laohu8.com/highlight/detail?id=2614024172","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614024172?lang=en_us&edition=fundamental","pubTime":"2026-02-27 01:05","pubTimestamp":1772125515,"startTime":"0","endTime":"0","summary":"Stifel says that it can see why uniQure’s (QURE) shares are lower on CNBC comments from FDA commissioner Marty Makary, where he was interviewed abo...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/stifel-says-uniqure-understandably-under-pressure-on-makary-comments-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/stifel-says-uniqure-understandably-under-pressure-on-makary-comments-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0109394709.USD","BK4139","LU0320765992.SGD","BK4127","SF","LU0889565916.HKD","QURE"],"gpt_icon":0},{"id":"2614028394","title":"Class Action Lawsuit Targets uniQure NV Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2614028394","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614028394?lang=en_us&edition=fundamental","pubTime":"2026-02-26 22:22","pubTimestamp":1772115731,"startTime":"0","endTime":"0","summary":"A class action lawsuit has been filed against uniQure NV on behalf of investors who bought or acquired its securities between September 24, 2025 and October 31, 2025. The complaint alleges the company misled investors about the effectiveness of its AMT-130 gene therapy candidate and the likelihood of accelerated FDA approval, and says later disclosures about unresolved FDA agreement and an uncertain BLA timeline contributed to a sharp share-price decline. Investors have until April 13, 2026 to seek appointment as lead plaintiff.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260226:nNDLRV97h:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0109394709.USD","QURE","LU0320765992.SGD","BK4139","LU0889565916.HKD"],"gpt_icon":0},{"id":"2614062661","title":"Rosen Law Firm Sets April 13 Lead Plaintiff Deadline in uniQure Securities Class Action","url":"https://stock-news.laohu8.com/highlight/detail?id=2614062661","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614062661?lang=en_us&edition=fundamental","pubTime":"2026-02-26 10:50","pubTimestamp":1772074205,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against uniQure NV on behalf of investors who bought its ordinary shares between September 24, 2025 and October 31, 2025. The suit alleges the company misrepresented or failed to disclose that aspects of its Huntington’s disease pivotal study design and comparison to external ENROLL-HD data were not fully approved by the FDA, and that it downplayed the likelihood it would need to delay its biologics license application timeline to conduct additional studies. An April 13, 2026 deadline has been set for investors to seek appointment as lead plaintiff.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260226:nNDL9Xdk03:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0109394709.USD","BK4139","LU0320765992.SGD","LU0889565916.HKD"],"gpt_icon":0},{"id":"2614849724","title":"Rosen Law Firm urges uniQure investors to act before April 13 lead plaintiff deadline","url":"https://stock-news.laohu8.com/highlight/detail?id=2614849724","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2614849724?lang=en_us&edition=fundamental","pubTime":"2026-02-25 07:47","pubTimestamp":1771976879,"startTime":"0","endTime":"0","summary":"A securities class action has been filed against uniQure NV on behalf of investors who bought shares between Sept. 24, 2025 and Oct. 31, 2025. The suit alleges the company misrepresented or omitted key information about FDA approval of its Huntington’s disease pivotal study design and the likelihood of delays to its biologics license application timeline, causing investor losses when details emerged. The deadline to seek appointment as lead plaintiff is April 13, 2026.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260224:nNDL9XTN29:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0320765992.SGD","QURE","LU0109394709.USD","LU0889565916.HKD","BK4139"],"gpt_icon":0},{"id":"2613071984","title":"uniQure Initiated at Peer Perform by Wolfe Research","url":"https://stock-news.laohu8.com/highlight/detail?id=2613071984","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613071984?lang=en_us&edition=fundamental","pubTime":"2026-02-24 20:29","pubTimestamp":1771936140,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/QURE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 24, 2026 07:29 ET (12:29 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0320765992.SGD","LU0109394709.USD","LU0889565916.HKD","BK4139"],"gpt_icon":0},{"id":"2613730575","title":"uniQure initiated with a Peer Perform at Wolfe Research","url":"https://stock-news.laohu8.com/highlight/detail?id=2613730575","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613730575?lang=en_us&edition=fundamental","pubTime":"2026-02-24 05:18","pubTimestamp":1771881523,"startTime":"0","endTime":"0","summary":"Wolfe Research initiated coverage of uniQure (QURE) with a Peer Perform rating and no price target The firm launched coverage of the neuroscience b...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/uniqure-initiated-with-a-peer-perform-at-wolfe-research-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/uniqure-initiated-with-a-peer-perform-at-wolfe-research-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["QURE","LU0109394709.USD","LU0320765992.SGD","LU0889565916.HKD","BK4139"],"gpt_icon":0},{"id":"2613781586","title":"uniQure NV updated its financial calendar","url":"https://stock-news.laohu8.com/highlight/detail?id=2613781586","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613781586?lang=en_us&edition=fundamental","pubTime":"2026-02-23 20:05","pubTimestamp":1771848313,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. uniQure NV published the original content used to generate this news brief via GlobeNewswire  on February 23, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260223:nNDL306pRS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","SG9999014021.USD","BK4139","QURE","IE00B3QW5Z07.USD","IE00B64PRP62.GBP","LU0889565916.HKD","NDAQ","BK4112","BK4585","LU2210150020.SGD","LU0109394709.USD","LU0320765992.SGD","SG9999014013.SGD","IE00BKPKM429.USD","SG9999014039.USD","LU2095319765.USD","IE00BGHQF748.EUR","LU2210149790.SGD","LU0314104364.USD","SG9999014005.SGD"],"gpt_icon":0},{"id":"2613781519","title":"uniQure to Announce 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2613781519","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2613781519?lang=en_us&edition=fundamental","pubTime":"2026-02-23 20:05","pubTimestamp":1771848300,"startTime":"0","endTime":"0","summary":"~ uniQure to host earnings call on Monday, March 2, 2026 at 8:00 a.m. ET ~LEXINGTON, Mass. and AMSTERDAM, Feb.  23, 2026  (GLOBE NEWSWIRE) -- uniQure N.V. (NASDAQ: QURE), a leading gene therapy compan","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/02/23/3242490/0/en/uniQure-to-Announce-2025-Financial-Results.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0109394709.USD","LU0889565916.HKD","LU0320765992.SGD","BK4139"],"gpt_icon":0},{"id":"2612644467","title":"Class Action Lawsuit Targets uniQure NV Over Alleged Securities Fraud","url":"https://stock-news.laohu8.com/highlight/detail?id=2612644467","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612644467?lang=en_us&edition=fundamental","pubTime":"2026-02-18 23:07","pubTimestamp":1771427220,"startTime":"0","endTime":"0","summary":"A securities fraud class action lawsuit has been filed against uniQure NV on behalf of investors who bought or acquired the company’s securities between Sept. 24, 2025 and Oct. 31, 2025. The suit alleges the company misled investors about the design and progress of its AMT-130 Huntington’s disease pivotal study and the likelihood of accelerated approval, and points to a sharp share-price drop after disclosures that the FDA did not accept certain study data as sufficient for a BLA submission. Investors seeking to be appointed lead plaintiff must file by April 13, 2026.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260218:nNDL5P9rZj:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0889565916.HKD","LU0320765992.SGD","BK4139","LU0109394709.USD"],"gpt_icon":0},{"id":"2612331944","title":"Investors Sue uniQure NV Over Alleged Misleading Disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2612331944","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612331944?lang=en_us&edition=fundamental","pubTime":"2026-02-17 08:15","pubTimestamp":1771287358,"startTime":"0","endTime":"0","summary":"A class action lawsuit has been filed against uniQure NV on behalf of investors who purchased shares between September 24, 2025, and October 31, 2025. The lawsuit alleges that the company misrepresented or failed to disclose that the design of its pivotal study for a Huntington's Disease drug was not fully approved by the FDA, and that additional studies might be required, potentially delaying its biologics license application. Investors claim they suffered damages when the true details became public. Those wishing to serve as lead plaintiff must act by April 13, 2026.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260217:nNDL1XJ0Zl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0109394709.USD","LU0320765992.SGD","LU0889565916.HKD","BK4139"],"gpt_icon":0},{"id":"2611919611","title":"uniQure Faces Class Action Over Alleged Misleading Statements on Drug Approval","url":"https://stock-news.laohu8.com/highlight/detail?id=2611919611","media":"Reuters","labels":["policyRegulatory","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2611919611?lang=en_us&edition=fundamental","pubTime":"2026-02-14 06:36","pubTimestamp":1771022178,"startTime":"0","endTime":"0","summary":"A class action lawsuit has been filed against uniQure NV on behalf of investors who purchased the company’s ordinary shares between September 24, 2025, and October 31, 2025. The litigation alleges that uniQure misled investors regarding the likelihood of FDA approval for its leading drug candidate, AMT-130. According to the complaint, the company failed to disclose that the design of its pivotal study was not fully approved by the FDA and that additional studies might be required, potentially delaying its biologics license application. On November 3, 2025, uniQure announced the FDA no longer agreed that the data from its Phase I/II studies would be adequate for primary evidence in a BLA submission, leading to a sharp drop in the company’s stock price. Investors wishing to serve as lead plaintiff must submit court papers by April 13, 2026. All representation is on a contingency fee basis, and shareholders pay no fees or expenses.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260213:nNDL34vqSy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0109394709.USD","BK4139","LU0889565916.HKD","LU0320765992.SGD"],"gpt_icon":0},{"id":"2610365964","title":"Assessing uniQure (QURE) Valuation After New Securities Fraud Lawsuit On AMT-130 Disclosures","url":"https://stock-news.laohu8.com/highlight/detail?id=2610365964","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610365964?lang=en_us&edition=fundamental","pubTime":"2026-02-12 04:28","pubTimestamp":1770841688,"startTime":"0","endTime":"0","summary":"Why the new lawsuit matters for uniQure stock\nA fresh securities fraud class action against uniQure (NasdaqGS:QURE) is putting a spotlight on how the company previously described AMT-130’s pivotal Huntington’s disease data and its interactions with the FDA.\nThe complaint challenges earlier messaging around biomarker results, comparisons with the ENROLL HD dataset, and the timeline for a potential Biologics License Application, which together influence how investors assess uniQure’s regulatory...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-qure/uniqure/news/assessing-uniqure-qure-valuation-after-new-securities-fraud","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-qure/uniqure/news/assessing-uniqure-qure-valuation-after-new-securities-fraud","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","LU0109394709.USD","QURE","LU0320765992.SGD","BK4219","BK4588","AMT","BK4084","LU0889565916.HKD","BK4581","BK4585","BK4554","BK4534"],"gpt_icon":0},{"id":"2610429086","title":"uniQure Price Target Maintained With a $70.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2610429086","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610429086?lang=en_us&edition=fundamental","pubTime":"2026-02-10 20:03","pubTimestamp":1770724980,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/QURE/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 10, 2026 07:03 ET (12:03 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QURE","LU0109394709.USD","BK4139","LU0889565916.HKD","LU0320765992.SGD"],"gpt_icon":0},{"id":"2610633391","title":"How Early AMT-191 Gene Therapy Signals Will Impact uniQure (QURE) Investors","url":"https://stock-news.laohu8.com/highlight/detail?id=2610633391","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610633391?lang=en_us&edition=fundamental","pubTime":"2026-02-09 14:08","pubTimestamp":1770617282,"startTime":"0","endTime":"0","summary":"uniQure N.V. recently reported updated preliminary safety and exploratory efficacy data from 11 patients in its ongoing Phase I/IIa trial of AMT-191, an investigational AAV gene therapy for Fabry disease, showing elevated α-galactosidase A activity across all three dose cohorts and a manageable safety profile.\nAn interesting early signal is that several participants have been able to discontinue enzyme replacement therapy, hinting at the potential real-world impact of a one-time gene therapy...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-qure/uniqure/news/how-early-amt-191-gene-therapy-signals-will-impact-uniqure-q","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-qure/uniqure/news/how-early-amt-191-gene-therapy-signals-will-impact-uniqure-q","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4585","BK4554","AMT","QURE","BK4581","LU0320765992.SGD","BK4534","LU0109394709.USD","BK4588","BK4219","LU0889565916.HKD","BK4211","BK4084","BK4139","ISBC"],"gpt_icon":0},{"id":"2609252515","title":"Early uniQure Fabry Trial Shows Lasting Enzyme Boost, Safety Watch","url":"https://stock-news.laohu8.com/highlight/detail?id=2609252515","media":"Benzinga_recent_news","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609252515?lang=en_us&edition=fundamental","pubTime":"2026-02-07 02:58","pubTimestamp":1770404280,"startTime":"0","endTime":"0","summary":"uniQure shares early trial data showing strong enzyme increases in Fabry patients, manageable safety results, and paused higher dosing after liver enzyme findings.","market":"sh","thumbnail":"https://cdn.benzinga.com/files/images/story/2026/02/06/Medicine-And-Health-Concept--On-A-White-.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2026/02/06/Medicine-And-Health-Concept--On-A-White-.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/news/health-care/26/02/50458873/early-uniqure-fabry-trial-shows-lasting-enzyme-boost-safety-watch","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/health-care/26/02/50458873/early-uniqure-fabry-trial-shows-lasting-enzyme-boost-safety-watch","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["LU0109394709.USD","LU0889565916.HKD","QURE","BK4139","LU0320765992.SGD"],"gpt_icon":0},{"id":"2609959857","title":"uniQure präsentiert neue Phase-I/IIa-Daten zur Gentherapie AMT-191 bei Fabry-Krankheit","url":"https://stock-news.laohu8.com/highlight/detail?id=2609959857","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609959857?lang=en_us&edition=fundamental","pubTime":"2026-02-06 20:05","pubTimestamp":1770379516,"startTime":"0","endTime":"0","summary":"Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. uniQure NV published the original content used to generate this news brief via GlobeNewswire  on February 06, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260206:nNDLbCktM9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","LU0314104364.USD","BK4112","LU0109394709.USD","NDAQ","IE00BKPKM429.USD","LU0889565916.HKD","QURE","LU2210149790.SGD","LU0320765992.SGD","LU2210150020.SGD","IE00B64PRP62.GBP","IE00BGHQF748.EUR","SG9999014013.SGD","SG9999014021.USD","BK4588","IE00B3QW5Z07.USD","SG9999014039.USD","BK4139","LU2095319765.USD","SG9999014005.SGD"],"gpt_icon":0},{"id":"2609598571","title":"uniQure Reports Sustained Enzyme Increases in Phase I/IIa Fabry Disease Gene Therapy Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2609598571","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609598571?lang=en_us&edition=fundamental","pubTime":"2026-02-06 20:05","pubTimestamp":1770379516,"startTime":"0","endTime":"0","summary":"uniQure NV has announced updated preliminary data from its Phase I/IIa clinical trial of AMT-191, an investigational AAV gene therapy for Fabry disease. The data, presented at the 22nd Annual WORLDSymposium on February 3, 2026, showed sustained and dose-dependent increases in α-Gal A enzyme activity across all dose cohorts, with supraphysiological expression maintained for over a year in the longest treated patient. Six out of eleven patients met criteria to discontinue enzyme replacement therapy, and stable plasma lyso-Gb3 levels were observed post-dosing, regardless of enzyme replacement therapy status. The safety profile remains manageable, with no serious adverse events related to AMT-191 at lower doses, though dosing in the mid- and high-dose cohorts has been paused following asymptomatic liver enzyme elevations in two patients. An oral presentation of the results is scheduled for February 6, 2026, and the presentation will be available on uniQure's website following the event.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260206:nNDLMPT6D:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0889565916.HKD","IE00BGHQF748.EUR","LU0109394709.USD","BK4585","LU0320765992.SGD","LU2095319765.USD","LU0314104364.USD","LU2210150020.SGD","SG9999014039.USD","BK4112","SG9999014021.USD","SG9999014013.SGD","SG9999014005.SGD","IE00BKPKM429.USD","NDAQ","LU2210149790.SGD","BK4588","BK4139","IE00B3QW5Z07.USD","QURE","IE00B64PRP62.GBP"],"gpt_icon":0}],"pageSize":20,"totalPage":8,"pageCount":1,"totalSize":142,"code":"91000000","status":"200"}]}}