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Rezolute, Inc.

3.28

-0.3350-9.27%

Post-market: 3.320.0400+1.22%17:12 EST

Volume:2.06M

Turnover:6.91M

Market Cap:313.89M

PE:-3.58

High:3.63

Open:3.61

Low:3.16

Close:3.62

52wk High:11.46

52wk Low:1.07

Shares:95.70M

Float Shares:72.51M

Volume Ratio:0.54

T/O Rate:2.85%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.9151

EPS(LYR):-0.9791

ROE:-74.02%

ROA:-44.09%

PB:2.45

PE(LYR):-3.35

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Overview Company News Filings

Faruqi & Faruqi Probes Investor Claims Against Rezolute Inc

Rezolute Publishes Corporate Presentation on Ersodetug for Hyperinsulinism-Related Hypoglycemia

Rezolute Q2 EPS $(0.22) Misses $(0.20) Estimate

Rare disease firm Rezolute's Q2 net loss widens

BRIEF-Rezolute Q2 EPS USD -0.22

Press Release: Rezolute Reports Second Quarter Fiscal 2026 Financial Results and Provides Business Update

Rezolute Inc. to Participate in Guggenheim Emerging Outlook Biotech Summit

Wedbush Doubles Price Target on Rezolute to $2 From $1, Keeps Neutral Rating

MT Newswires Live

Rezolute Price Target Maintained With a $5.00/Share by BTIG

BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe's

Rezolute Shares Gain on Positive Ersodetug Indicators Despite Failure to Meet Trial Goals

BUZZ-U.S. STOCKS ON THE MOVE-Hershey, Praxis Precision, Cal-Maine Foods

BUZZ-Rezolute rises as drug shows promise for rare low blood sugar disorders

Rezolute Inc. unveils presentation on late-stage therapies for hyperinsulinism and hypoglycemia

Rezolute Provides Insights From Its Phase 3 Sunrize Study in Congenital Hyperinsulinism and Shares Findings From Its Expanded Access Program in Tumor Hyperinsulinism

THOMSON REUTERS

Rezolute Reports Phase 3 sunRIZE Study Results for Ersodetug in Congenital Hyperinsulinism

Rezolute (RZLT) Valuation Revisited After Phase 3 sunRIZE Trial Misses Primary and Key Secondary Endpoints

Simply Wall St.

Rezolute Inc. Chief Medical Officer Brian Kenneth Roberts Acquires Common Shares

Rezolute Inc. CFO Daron Evans Reports Acquisition of Common Shares

Rezolute Inc. Chief Commercial Officer Sunil Ratilal Karnawat Acquires Common Shares

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& Faruqi Probes Investor Claims Against Rezolute Inc","url":"https://stock-news.laohu8.com/highlight/detail?id=2612285515","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612285515?lang=en_us&edition=fundamental","pubTime":"2026-02-19 22:51","pubTimestamp":1771512672,"startTime":"0","endTime":"0","summary":"Faruqi & Faruqi said it is investigating potential securities claims on behalf of investors in Rezolute Inc. following a sharp selloff in the company’s shares after disappointing topline results from its Phase 3 sunRIZE trial of ersodetug for congenital hyperinsulinism. The firm alleges investors who suffered significant losses in Rezolute stock or options may have legal rights and is seeking to speak with affected shareholders.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260219:nNDLbz49WW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210149790.SGD","LU0314104364.USD","SG9999014039.USD","BK4112","SG9999014005.SGD","SG9999014013.SGD","BK4585","IE00BKPKM429.USD","LU2095319765.USD","BK4139","IE00B3QW5Z07.USD","IE00BGHQF748.EUR","BK4588","RZLT","LU2210150020.SGD","SG9999014021.USD","IE00B64PRP62.GBP","NDAQ"],"gpt_icon":0},{"id":"2612207924","title":"Rezolute Publishes Corporate Presentation on Ersodetug for Hyperinsulinism-Related Hypoglycemia","url":"https://stock-news.laohu8.com/highlight/detail?id=2612207924","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2612207924?lang=en_us&edition=fundamental","pubTime":"2026-02-19 07:48","pubTimestamp":1771458484,"startTime":"0","endTime":"0","summary":"Rezolute Inc. highlighted its lead program, RZ358 , a fully human monoclonal antibody designed to treat hypoglycemia caused by hyperinsulinism by allosterically modulating the insulin receptor. The company discussed development across two indications—congenital hyperinsulinism and tumor hyperinsulinism—including Phase 2b RIZE data and Phase 3 sunRIZE study design and outcomes, and noted ongoing clinical and expanded access experience. Rezolute also referenced its cash position of $133 million with runway to mid-2027 and outlined upcoming milestones, including planned FDA engagement for congenital hyperinsulinism in Q1 2026 and expected topline data for tumor hyperinsulinism in the second half of 2026. You can access the full presentation through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260218:nNDL2rDLwn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2611903556","title":"Rezolute Q2 EPS $(0.22) Misses $(0.20) Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2611903556","media":"Benzinga","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2611903556?lang=en_us&edition=fundamental","pubTime":"2026-02-13 05:50","pubTimestamp":1770933002,"startTime":"0","endTime":"0","summary":"Rezolute (NASDAQ:RZLT) reported quarterly losses of $(0.22) per share which missed the analyst consensus estimate of $(0.20) by 12.82 percent. This is unchanged from the same period last year.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/02/50598563/rezolute-q2-eps-0-22-misses-0-20-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Rezolute Q2 EPS $(0.22) Misses $(0.20) Estimate","news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["JEPQ","QYLG","BK4139","NVIW.SI",".IXIC","QQQY","QQQJ","QQQE","USAW.SI","USJW.SI","MNQmain","QLD","RZLT","SQQQ","NQmain","QYLD","QID","TSYW.SI","GPIQ","TQQQ","PSQ"],"gpt_icon":0},{"id":"2611563908","title":"Rare disease firm Rezolute's Q2 net loss widens","url":"https://stock-news.laohu8.com/highlight/detail?id=2611563908","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2611563908?lang=en_us&edition=fundamental","pubTime":"2026-02-13 05:28","pubTimestamp":1770931713,"startTime":"0","endTime":"0","summary":"Rare disease firm Rezolute's Q2 net loss widensOverviewRare disease company reported Q2 fiscal 2026 net loss of $22.8 mln, up from last yearR&D expenses rose to $14.3 mln due to increased clinical tri","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260212:nL1N3Z81G5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2611497779","title":"BRIEF-Rezolute Q2 EPS USD -0.22","url":"https://stock-news.laohu8.com/highlight/detail?id=2611497779","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2611497779?lang=en_us&edition=fundamental","pubTime":"2026-02-13 05:05","pubTimestamp":1770930346,"startTime":"0","endTime":"0","summary":"BRIEF-Rezolute Q2 EPS USD -0.22\n\n\nFeb 12 (Reuters) - Rezolute Q2 income from operations USD -24.221 million.\n\nQ2 operating expenses USD 24.221 million\nQ2 net income USD -22.774 million","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260212:nPLXB6E4BF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2611297770","title":"Press Release: Rezolute Reports Second Quarter Fiscal 2026 Financial Results and Provides Business Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2611297770","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2611297770?lang=en_us&edition=fundamental","pubTime":"2026-02-13 05:05","pubTimestamp":1770930300,"startTime":"0","endTime":"0","summary":"REDWOOD CITY, Calif., Feb. 12, 2026  -- Rezolute, Inc.  , a late-stage rare disease company focused on treating hypoglycemia caused by all forms of hyperinsulinism , today reported financial results and provided a business update for the three months ended December 31, 2025.-- In December 2025, Rezolute reported topline results from sunRIZE, a Phase. efficacy study of ersodetug for the treatment of congenital HI. The study. did not meet its primary or key secondary endpoints.-- The study demonstrated reductions from baseline in hypoglycemia. events by self-monitored blood glucose at both ersodetug dose. levels, but reductions were not statistically significant compared. to placebo, due to a pronounced study effect. was also demonstrated with both dose levels of ersodetug,which was statistically significant compared to placebo at the. Week 16 timepoint, but did not meet significance at the Week 24. therapeutic drug concentrations achieved in both treatment groups,into the ongoing open-l","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2360032135.SGD","BK4161","HI","LU0128526141.USD","LU0029874061.USD","LU2125154935.USD","RZLT","LU2125154778.USD","BK4139"],"gpt_icon":0},{"id":"2608366867","title":"Rezolute Inc. to Participate in Guggenheim Emerging Outlook Biotech Summit","url":"https://stock-news.laohu8.com/highlight/detail?id=2608366867","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2608366867?lang=en_us&edition=fundamental","pubTime":"2026-02-04 20:00","pubTimestamp":1770206418,"startTime":"0","endTime":"0","summary":"Rezolute Inc., a late-stage rare disease company focused on treating hypoglycemia caused by hyperinsulinism, will participate in the Guggenheim Emerging Outlook: Biotech Summit 2026, which takes place on February 11-12, 2026, in New York. The company’s management team will hold one-on-one investor meetings throughout the conference.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Rezolute Inc. published the original content used to generate this news brief via GlobeNewswire  on February 04, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260204:nNDL45Yz5k:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","SG9999014039.USD","IE00BKPKM429.USD","LU2210149790.SGD","IE00BGHQF748.EUR","SG9999014013.SGD","SG9999014005.SGD","BK4139","LU2095319765.USD","NDAQ","IE00B3QW5Z07.USD","IE00B64PRP62.GBP","LU0314104364.USD","LU2210150020.SGD","SG9999014021.USD","RZLT","BK4112","BK4588"],"gpt_icon":0},{"id":"2601610293","title":"Wedbush Doubles Price Target on Rezolute to $2 From $1, Keeps Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2601610293","media":"MT Newswires Live","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601610293?lang=en_us&edition=fundamental","pubTime":"2026-01-08 20:58","pubTimestamp":1767877130,"startTime":"0","endTime":"0","summary":"Rezolute (RZLT) has an average rating of overweight and mean price target of $4.25, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major bank","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","RZLT"],"gpt_icon":0},{"id":"2601350035","title":"Rezolute Price Target Maintained With a $5.00/Share by BTIG","url":"https://stock-news.laohu8.com/highlight/detail?id=2601350035","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601350035?lang=en_us&edition=fundamental","pubTime":"2026-01-08 18:25","pubTimestamp":1767867900,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/RZLT/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  January 08, 2026 05:25 ET (10:25 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2601383269","title":"BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe's","url":"https://stock-news.laohu8.com/highlight/detail?id=2601383269","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601383269?lang=en_us&edition=fundamental","pubTime":"2026-01-08 02:51","pubTimestamp":1767811889,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Nvidia, Boeing, Lowe'sEikon search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call newsletter: https://ref","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL6N3Y80LY:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GE","RTX","CL","CALM","VTYX","COMP","LOW","ACI","UNP","IONS","EXE","CDE","AIR","UNF","PENG","PRAX","HUM","HSY","GLUE","MTYY","DECK","RZLT","NEM","W","BKR","CRNX","SLB","TXR","VERA","FSLR","ARWR","AJG","APOG","LNG","LBRT","NVDA","BA","HAL","HL","LMT","MTB"],"gpt_icon":1},{"id":"2601807662","title":"Rezolute Shares Gain on Positive Ersodetug Indicators Despite Failure to Meet Trial Goals","url":"https://stock-news.laohu8.com/highlight/detail?id=2601807662","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601807662?lang=en_us&edition=fundamental","pubTime":"2026-01-08 00:30","pubTimestamp":1767803400,"startTime":"0","endTime":"0","summary":"Rezolute shares climbed after the pharmaceutical company said data from a Phase 3 trial of  ersodetug for congenital hyperinsulinism supported evidence that the drug is active against hypoglycemia, despite failing to meet the trial's primary or key secondary endpoints.Shares were up 16% to $2.22 late Wednesday morning. The stock is down 56% in the past year.Shares plummeted last month after Rezolute said ersodetug failed to meet its goals in the sunRIZE trial of reducing and shortening hypoglycemia events. But the company said Wednesday that the drug did demonstrate reductions in the frequency and time of hypoglycemia events, though not to the level of statistical significance.\"While in the early stages of evaluating study data and understanding the results, learnings in the field of glycemic control and initial observations from sunRIZE inform the Company's belief that the pharmacologic response can translate to clinical efficacy,\" Rezolute said Wednesday.Rezolute said it looks forwar","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Rezolute Shares Gain on Positive Ersodetug Indicators Despite Failure to Meet Trial Goals","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2601809779","title":"BUZZ-U.S. STOCKS ON THE MOVE-Hershey, Praxis Precision, Cal-Maine Foods","url":"https://stock-news.laohu8.com/highlight/detail?id=2601809779","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601809779?lang=en_us&edition=fundamental","pubTime":"2026-01-07 22:26","pubTimestamp":1767795994,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-Hershey, Praxis Precision, Cal-Maine FoodsEikon search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call new","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL6N3Y80LX:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MST","SMI3.UK","PRAX","MTB","07399","HOUS","AIR","APOG","COMP","BAC","NEM","09799","HL","VERA","VTYX","TXR","GLUE","MSCI","MSTY.UK","DECK","HSY","IMST","CDE","HUM","CALM","LMI3.UK","ARWR","CRNX","RZLT","CL","UNP","MSST","LMT","MSTK","RTX","PENG","WNTR","MSTY","AJG","SMST","FSLR","MSII"],"gpt_icon":1},{"id":"2601808505","title":"BUZZ-Rezolute rises as drug shows promise for rare low blood sugar disorders","url":"https://stock-news.laohu8.com/highlight/detail?id=2601808505","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601808505?lang=en_us&edition=fundamental","pubTime":"2026-01-07 20:31","pubTimestamp":1767789091,"startTime":"0","endTime":"0","summary":"BUZZ-Rezolute rises as drug shows promise for rare low blood sugar disorders** Shares of drug developer Rezolute RZLT.O rise 2.1% to $1.95 premarket** Co says late-stage trial of ersodetug in congenital hyperinsulinism missed main goals but showed drug activity** Congenital HI causes frequent severe drops in blood sugar; all 59 patients opted for extension study, RZLT says** Some children stopped other treatments, relying only on ersodetug, co says** Expanded access program in tumor-related HI saw 75% patients stop hospital glucose infusions, RZLT says** Co plans FDA meeting early this year** Ersodetug aims to block excess insulin effects; drug generally well-tolerated so far, co says** As of last close, stock down ~19% over the past year   ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nL4N3Y80SR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2601830808","title":"Rezolute Inc. unveils presentation on late-stage therapies for hyperinsulinism and hypoglycemia","url":"https://stock-news.laohu8.com/highlight/detail?id=2601830808","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601830808?lang=en_us&edition=fundamental","pubTime":"2026-01-07 20:23","pubTimestamp":1767788585,"startTime":"0","endTime":"0","summary":"Rezolute Inc. has outlined progress in its late-stage rare disease programs targeting hyperinsulinism, a serious condition characterized by excessive insulin production leading to hypoglycemia. The company’s lead candidate, ersodetug , is an antibody therapy being evaluated for both congenital and tumor-induced hyperinsulinism. Ersodetug has received Breakthrough Therapy Designation from the US FDA, PRIME designation from the European Medicines Agency, and Orphan Drug Designation in both the US and EU. Data from clinical trials and real-world use suggest activity against hypoglycemia in patients with hyperinsulinism. Rezolute plans to report topline data from a Phase 3 trial in tumor hyperinsulinism in the second half of 2026, with ongoing regulatory engagement for congenital hyperinsulinism. Current standard of care remains inadequate, as a significant portion of patients do not respond to existing therapies such as diazoxide and may experience serious side effects. You can access the","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nNDL6rBdF5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RZLT"],"gpt_icon":0},{"id":"2601487053","title":"Rezolute Provides Insights From Its Phase 3 Sunrize Study in Congenital Hyperinsulinism and Shares Findings From Its Expanded Access Program in Tumor Hyperinsulinism","url":"https://stock-news.laohu8.com/highlight/detail?id=2601487053","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601487053?lang=en_us&edition=fundamental","pubTime":"2026-01-07 20:01","pubTimestamp":1767787271,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nFWN3Y7186:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2601532872","title":"Rezolute Reports Phase 3 sunRIZE Study Results for Ersodetug in Congenital Hyperinsulinism","url":"https://stock-news.laohu8.com/highlight/detail?id=2601532872","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2601532872?lang=en_us&edition=fundamental","pubTime":"2026-01-07 19:11","pubTimestamp":1767784305,"startTime":"0","endTime":"0","summary":"Rezolute Inc. announced insights from its Phase 3 sunRIZE study evaluating ersodetug in patients with congenital hyperinsulinism  and shared findings from its Expanded Access Program  in tumor-induced HI. According to the company, data from both the sunRIZE study and the EAP demonstrate evidence of activity of ersodetug in these indications. In the EAP, 75% of patients previously dependent on intravenous dextrose or total parenteral nutrition were able to completely discontinue these treatments. Additionally, more than a dozen patients with severe and refractory hypoglycemia due to tumor HI reportedly experienced substantial improvements, including reduced glucose infusion rates or complete discontinuation of infusion. The results from these studies have already been presented and discussed with the U.S. Food and Drug Administration. Rezolute plans to continue discussions with the FDA regarding the path forward for congenital HI.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260107:nNDL6tYdjM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2594250337","title":"Rezolute (RZLT) Valuation Revisited After Phase 3 sunRIZE Trial Misses Primary and Key Secondary Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2594250337","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2594250337?lang=en_us&edition=fundamental","pubTime":"2025-12-26 06:17","pubTimestamp":1766701047,"startTime":"0","endTime":"0","summary":"Rezolute (RZLT) just released topline data from its pivotal Phase 3 sunRIZE trial in congenital hyperinsulinism, and the drug missed both primary and key secondary endpoints, forcing investors to quickly reassess the story.\nSee our latest analysis for Rezolute.\nThe setback helps explain why Rezolute’s 30 day share price return sits at around negative 72 percent even after a sharp short term rebound. The share price closed at 2.74 dollars, and while the three year total shareholder return is...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rzlt/rezolute/news/rezolute-rzlt-valuation-revisited-after-phase-3-sunrize-tria","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-rzlt/rezolute/news/rezolute-rzlt-valuation-revisited-after-phase-3-sunrize-tria","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","RZLT","DCF"],"gpt_icon":0},{"id":"2592943123","title":"Rezolute Inc. Chief Medical Officer Brian Kenneth Roberts Acquires Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2592943123","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2592943123?lang=en_us&edition=fundamental","pubTime":"2025-12-18 05:14","pubTimestamp":1766006062,"startTime":"0","endTime":"0","summary":"Brian Kenneth Roberts, Chief Medical Officer, reported the acquisition of common shares of Rezolute Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Rezolute Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 17, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251217:nNDL31Xc07:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Rezolute Inc. Chief Medical Officer Brian Kenneth Roberts Acquires Common Shares","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2591167325","title":"Rezolute Inc. CFO Daron Evans Reports Acquisition of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2591167325","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591167325?lang=en_us&edition=fundamental","pubTime":"2025-12-16 08:36","pubTimestamp":1765845392,"startTime":"0","endTime":"0","summary":"Daron Evans, Chief Financial Officer of Rezolute Inc., has reported the acquisition of common shares of Rezolute Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Rezolute Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 15, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251216:nNDL6GK4V5:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RZLT","BK4139"],"gpt_icon":0},{"id":"2591673479","title":"Rezolute Inc. Chief Commercial Officer Sunil Ratilal Karnawat Acquires Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2591673479","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2591673479?lang=en_us&edition=fundamental","pubTime":"2025-12-16 08:35","pubTimestamp":1765845325,"startTime":"0","endTime":"0","summary":"Sunil Ratilal Karnawat, Chief Commercial Officer of Rezolute Inc., reported the acquisition of common shares of Rezolute Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Rezolute Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 15, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251216:nNDL4vNS0W:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Rezolute Inc. Chief Commercial Officer Sunil Ratilal Karnawat Acquires Common Shares","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","RZLT"],"gpt_icon":0}],"pageSize":20,"totalPage":5,"pageCount":1,"totalSize":92,"code":"91000000","status":"200"}]}}