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Septerna, Inc.

6.45

-0.7100-9.92%

Pre-market: 6.550.1000+1.55%08:23 EDT

Volume:223.18K

Turnover:1.47M

Market Cap:286.65M

PE:-0.89

High:7.04

Open:7.04

Low:6.42

Close:7.16

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Overview Company News Filings

Septerna Insiders Placed Bullish Bets Worth US$934.3k

Simply Wall St.

Septerna, Inc. Reports 2024 Financial Results and Strategic Progress

Septerna, Inc. (SEPN) Receives a Hold from Wells Fargo

U.S. RESEARCH ROUNDUP-Applied Materials, KLA, Oxford Industries

BRIEF-Septerna Provides Corporate Overview And Reports Fourth Quarter And Full Year 2024 Financial Results

Septerna reports Q4 EPS (64c), consensus (69c)

Septerna sees cash runway into early 2028

Septerna Q4 EPS $(0.64) Beats $(0.69) Estimate, Sales $212.00K Beat $150.00K Estimate

Septerna Inc: Qtrly Shr Loss $0.64

THOMSON REUTERS

Septerna Provides Corporate Overview and Reports Fourth Quarter and Full Year 2024 Financial Results

THOMSON REUTERS

Press Release: Septerna Provides Corporate Overview and Reports Fourth Quarter and Full Year 2024 Financial Results

Septerna, Inc. (SEPN): Among Top Insider Purchases Last Month

Septerna, Inc. Shifts Focus to Next-Gen PTH1R Agonist

Major Investment Alert: Third Rock Ventures Boosts Stake in Septerna, Inc.

Major Investment Alert: Septerna, Inc. Gains a Boost from Third Rock Ventures!

Biotech Stock Roundup: MRNA's Q4 Results, GILD's Update & Other News

Septerna Cut to Equal-Weight From Overweight by Wells Fargo

Top Midday Decliners

MT Newswires Live

Septerna Stock Plummets to New Low After Ending Trial

BRIEF-Septerna Announces Discontinuation of SEP-786 Phase 1 Clinical Trial

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Septerna (SEPN) expects its current cash position...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-sees-cash-runway-into-early-2028?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-sees-cash-runway-into-early-2028?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","SEPN"],"gpt_icon":0},{"id":"2522724823","title":"Septerna Q4 EPS $(0.64) Beats $(0.69) Estimate, Sales $212.00K Beat $150.00K Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2522724823","media":"Benzinga","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2522724823?lang=en_us&edition=fundamental","pubTime":"2025-03-27 20:04","pubTimestamp":1743077064,"startTime":"0","endTime":"0","summary":"Septerna (NASDAQ:SEPN) reported quarterly losses of $(0.64) per share which beat the analyst consensus estimate of $(0.69) by 7.25 percent. 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Phase 1 Trial for SEP-631, MRGPRX2 NAM Program for Mast Cell Diseases, Expected to Initiate in 2025. Well-Capitalized with $420.8M Balance Sheet as of YE 2024 to Support Operating Runway into Early 2028. SOUTH SAN FRANCISCO, Calif., March 27, 2025  -- Septerna, Inc. , a biotechnology company pioneering a new era of G protein-coupled receptor  drug discovery, today provided a corporate overview complete with upcoming milestones and reported fourth quarter and full year 2024 financial results.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["TM","BK4585","BK4599","03160","GPCR","BK4007","BK4588","BK4604","BK4555","SEPN","BK4099"],"gpt_icon":0},{"id":"2519819833","title":"Septerna, Inc. (SEPN): Among Top Insider Purchases Last Month","url":"https://stock-news.laohu8.com/highlight/detail?id=2519819833","media":"Insider Monkey","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2519819833?lang=en_us&edition=fundamental","pubTime":"2025-03-14 23:26","pubTimestamp":1741965998,"startTime":"0","endTime":"0","summary":"We recently published a list of Top 10 Insider Purchases Last Month. In this article, we are going to take a look at where Septerna, Inc.  stands against other top insider purchases last month.How will new tariffs impact the U.S. economy?What’s next on President Trump’s geopolitical agenda?These are some of the concerning questions influencing market conditions.According to J.P. Morgan’s chief global economist, Bruce Kasman, there is about a 40% chance of a U.S. recession and a risk of lasting damage to the country’s reputation as an investment destination, writes Reuters.“Where we stand now is with a heightened concern about the U.S. economy,” Kasman said to reporters in Singapore on Wednesday.Additionally, Goldman Sachs lowered its 2025-end target for the broader market. “The proximate causes of the market decline are the jump in policy uncertainty largely related to tariffs, concerns about the economic growth outlook, and a positioning unwind, especially among hedge funds,” analysts","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/septerna-inc-sepn-among-top-152638628.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0061475181.USD","LU2237443549.SGD","IE00B19Z3581.USD","BK4585","BK4007","LU1868837136.USD","BK4550","IE00B19Z3B42.SGD","LU0106831901.USD","LU1868836914.USD","IE0004091025.USD","IE00BSNM7G36.USD","LU2471134796.USD","LU2237443465.HKD","BK4504","LU1868837300.USD","LU2471134952.CNY","LU2471134523.USD","IE00BFXG1179.USD","LU2237438978.USD","LU2471134879.HKD","LU1868836757.USD","LU2237443895.HKD","BK4552","LU0096364046.USD","BK4127","GPCR","LU2237443978.SGD","BK4599","IE0004086264.USD","IE0002270589.USD","IE0034235188.USD","LU2750360997.AUD","LU1868836591.USD","LU2237443622.USD","BK4516","LU2237443382.USD","LU1668664300.SGD","BK4533","BK4588","LU2750360641.GBP","LU1791807156.HKD","SEPN"],"gpt_icon":0},{"id":"2516646336","title":"Septerna, Inc. Shifts Focus to Next-Gen PTH1R Agonist","url":"https://stock-news.laohu8.com/highlight/detail?id=2516646336","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516646336?lang=en_us&edition=fundamental","pubTime":"2025-03-04 06:18","pubTimestamp":1741040316,"startTime":"0","endTime":"0","summary":"An announcement from Septerna, Inc. ( ($SEPN) ) is now available. Septerna, Inc. announced its participation in the TD Cowen 45th Annual Health Car...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/septerna-inc-shifts-focus-to-next-gen-pth1r-agonist?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/septerna-inc-shifts-focus-to-next-gen-pth1r-agonist?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4588","BK4007","BK4097","LU2286300806.USD","BK4585","SEPN","GEN"],"gpt_icon":0},{"id":"2514281485","title":"Major Investment Alert: Third Rock Ventures Boosts Stake in Septerna, Inc.","url":"https://stock-news.laohu8.com/highlight/detail?id=2514281485","media":"TIPRANKS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514281485?lang=en_us&edition=fundamental","pubTime":"2025-02-27 10:16","pubTimestamp":1740622593,"startTime":"0","endTime":"0","summary":"New insider activity at Septerna, Inc. ( ($SEPN) ) has taken place on February 27, 2025. Significant shareholder Third Rock Ventures VI, L.P. has m...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/insider-trading/major-investment-alert-third-rock-ventures-boosts-stake-in-septerna-inc?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/insider-trading/major-investment-alert-third-rock-ventures-boosts-stake-in-septerna-inc?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","BK4007"],"gpt_icon":0},{"id":"2514708734","title":"Major Investment Alert: Septerna, Inc. Gains a Boost from Third Rock Ventures!","url":"https://stock-news.laohu8.com/highlight/detail?id=2514708734","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514708734?lang=en_us&edition=fundamental","pubTime":"2025-02-25 10:10","pubTimestamp":1740449457,"startTime":"0","endTime":"0","summary":"New insider activity at Septerna, Inc. ( ($SEPN) ) has taken place on February 25, 2025. Significant shareholder Third Rock Ventures VI, L.P. has m...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/insider-trading/major-investment-alert-septerna-inc-gains-a-boost-from-third-rock-ventures?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/insider-trading/major-investment-alert-septerna-inc-gains-a-boost-from-third-rock-ventures?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","SEPN"],"gpt_icon":0},{"id":"2512648441","title":"Biotech Stock Roundup: MRNA's Q4 Results, GILD's Update & Other News","url":"https://stock-news.laohu8.com/highlight/detail?id=2512648441","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512648441?lang=en_us&edition=fundamental","pubTime":"2025-02-19 22:39","pubTimestamp":1739975940,"startTime":"0","endTime":"0","summary":"It was a busy week for the biotech sector. While the fourth-quarter earnings season continues, other pipeline and regulatory updates were also in focus.Moderna MRNA reported a loss of $2.50 per share in the fourth quarter of 2024, narrower than the Zacks Consensus Estimate of a loss of $2.69. In the year-ago period, the company had reported earnings of 55 cents per share.Revenues declined 64% year over year to $966 million, primarily due to the declining sales of its COVID-19 vaccine and the soft sales performance of its recently launched RSV vaccine.MRNA recorded $923 million in Spikevax sales for the fourth quarter of 2024 compared with $2.8 billion in the year-ago quarter.Moderna reiterated its total revenue guidance for 2025, which was issued last month. It expects total revenues to be in the range of $1.5-$2.5 billion, mainly from product sales of its COVID-19 and RSV vaccines. Owing to the seasonality of its business, management expects to generate around $0.2 billion in revenues","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/biotech-stock-roundup-mrnas-q4-143900726.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1430594728.SGD","LU1066053197.SGD","LU1585245621.USD","LU1571399168.USD","BK4568","IE00B19Z3B42.SGD","IE00BSNM7G36.USD","LU0234570918.USD","BK4139","SEPN","LU1066051498.USD","BK4585","LU0109394709.USD","LU0320765992.SGD","LU2087621335.USD","BK4588","BK4501","IE00BZ1G4Q59.USD","BK4534","IE00B7SZLL34.SGD","GILD","BK4548","IE00BKVL7J92.USD","LU2468319806.SGD","BK4533","LU0289739699.SGD","BK4578","IE00B19Z3581.USD","IE0002270589.USD","BK4566","BK4007","BK4583","IE00B3T34201.USD","LU2089984988.USD","LU0058720904.USD","BK4550","LU1839511570.USD","LU0889565916.HKD","SLDB","MRNA","BK4551","BK4532"],"gpt_icon":1},{"id":"2512116601","title":"Septerna Cut to Equal-Weight From Overweight by Wells Fargo","url":"https://stock-news.laohu8.com/highlight/detail?id=2512116601","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512116601?lang=en_us&edition=fundamental","pubTime":"2025-02-19 07:12","pubTimestamp":1739920320,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 18, 2025 18:12 ET (23:12 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"gpt_icon":0},{"id":"2512874195","title":"Top Midday Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2512874195","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512874195?lang=en_us&edition=fundamental","pubTime":"2025-02-19 02:37","pubTimestamp":1739903829,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) shares sank 59% amid heavy trading after the company said Tuesday it discontinued a phase 1 clinical trial of SEP-786 to treat hypoparathyroidism in healthy volunteers.Intraday trading","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0320765489.SGD","LU0158827781.USD","IE00B3T34201.USD","LU0158827948.USD","LU2111349929.HKD","IE000M9KFDE8.USD","IE00BFXG1179.USD","LU1116320901.HKD","IE00BQXX3F31.USD","LU0211326839.USD","LU0265550946.USD","MDT","SEPN","LU0070302665.USD","LU0265550359.USD","BK4585","LU1989764748.USD","LU0208291251.USD","LU1291159041.SGD","LU2089284900.SGD","LU2468319806.SGD","LU0211331839.USD","LU0976567544.SGD","LU1983299246.USD","LU1116320737.USD","BK4588","BK4007","LU2089283258.USD","LU0162691827.USD","LU0072461881.USD","LU0496365809.HKD","LU1989764664.SGD","BK4566","BK4557","IE00BQXX3C00.GBP","LU1571399168.USD","LU2028103732.USD","BK4159","BK4082","LU2271345857.HKD","LU0211326755.USD","GNLN","LU1989771016.USD","IE00BQXX3D17.EUR","LU2023251221.USD","BK4533","LU2089984988.USD"],"gpt_icon":0},{"id":"2512161153","title":"Septerna Stock Plummets to New Low After Ending Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2512161153","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512161153?lang=en_us&edition=fundamental","pubTime":"2025-02-18 23:26","pubTimestamp":1739892360,"startTime":"0","endTime":"0","summary":"The stock fell 68% to a low of $4.17 in early trading. The stock just hit the market last fall.The clinical-stage biotech company said Tuesday that it would stop the trial based on two unanticipated and severe events that didn't cause liver injury or other serious adverse effects, but prompted the discontinuation of dosing for both study participants.The company said it would initiate non-clinical studies to investigate what was observed during phase 1.","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"gpt_icon":0},{"id":"2512544166","title":"BRIEF-Septerna Announces Discontinuation of SEP-786 Phase 1 Clinical Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2512544166","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512544166?lang=en_us&edition=fundamental","pubTime":"2025-02-18 22:55","pubTimestamp":1739890527,"startTime":"0","endTime":"0","summary":"BRIEF-Septerna Announces Discontinuation of SEP-786 Phase 1 Clinical TrialFeb 18 (Reuters) - Septerna Inc SEPN.O:SEPTERNA ANNOUNCES DISCONTINUATION OF SEP-786 PHASE 1 CLINICAL TRIAL AND PLANS TO 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