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Septerna, Inc.

22.02

-1.2450-5.35%

Volume:123.67K

Turnover:2.77M

Market Cap:985.93M

PE:-15.45

High:23.15

Open:22.68

Low:21.85

Close:23.27

52wk High:28.99

52wk Low:4.17

Shares:44.77M

Float Shares:18.20M

Volume Ratio:0.82

T/O Rate:0.68%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.4257

EPS(LYR):-7.2588

ROE:-22.38%

ROA:-14.32%

PB:2.54

PE(LYR):-3.03

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Overview Company News Filings

Septerna (SEPN) Is Up 25.7% After Turning Profitable on Strong Q3 Sales and Analyst Optimism Has The Bull Case Changed?

Simply Wall St.

Septerna Shares Rise After Wells Fargo Upgrade

MT Newswires Live

BUZZ-U.S. STOCKS ON THE MOVE-Molina Healthcare, Memory chip makers, Binah Capital

Stock Track | Septerna Soars 5.25% as Wells Fargo Upgrades to Overweight, Citing Promising Drug Pipeline

Septerna Raised to Overweight From Equal-Weight by Wells Fargo

BUZZ-Septerna rises after Wells Fargo upgrades to 'overweight'

Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN), Applied Materials (AMAT) and Nvidia (NVDA)

Shares of Septerna up 1.7% Premarket After Wells Fargo Raises to 'Overweight' From 'Equal Weight'

THOMSON REUTERS

GFL Environmental Inc. : Wells Fargo Initiates Coverage With Overweight Rating; Target Price C$68

THOMSON REUTERS

Septerna, Inc. : Wells Fargo Raises to Overweight From Equal Weight

THOMSON REUTERS

Wells Fargo Upgrades Septerna to Overweight From Equalweight, Adjusts Price Target to $28 From $18

MT Newswires Live

Septerna SVP Daniel D. Long Reports Sale of Common Shares

Stock Track | Septerna Soars 5.55% as HC Wainwright Raises Price Target

Stock Track | Septerna (SEPN) Soars 5.55% as HC Wainwright Maintains Buy Rating and Raises Price Target

Septerna Is Maintained at Buy by HC Wainwright & Co.

Analysts Offer Insights on Technology Companies: Lightpath Technologies (LPTH) and Septerna, Inc. (SEPN)

Septerna Swings to Q3 Earnings, Revenue Rises

MT Newswires Live

Septerna Reports Q3 Cash Position of $561.6 Million

Press Release: Septerna Highlights Company Progress and Reports Third Quarter 2025 Financial Results

Septerna to Participate in Upcoming Investor Conferences

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Soars 5.25% as Wells Fargo Upgrades to Overweight, Citing Promising Drug Pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=1172365512","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1172365512?lang=en_us&edition=fundamental","pubTime":"2025-11-14 22:32","pubTimestamp":1763130743,"startTime":"0","endTime":"0","summary":"Septerna, Inc. (SEPN) shares are soaring 5.25% in Friday's pre-market trading following a significant upgrade from Wells Fargo. The investment bank raised its rating on the drug developer from Equal...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SEPN"],"gpt_icon":0},{"id":"2583350119","title":"Septerna Raised to Overweight From Equal-Weight by Wells Fargo","url":"https://stock-news.laohu8.com/highlight/detail?id=2583350119","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583350119?lang=en_us&edition=fundamental","pubTime":"2025-11-14 21:59","pubTimestamp":1763128740,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 14, 2025 08:59 ET (13:59 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"gpt_icon":0},{"id":"2583509672","title":"BUZZ-Septerna rises after Wells Fargo upgrades to 'overweight'","url":"https://stock-news.laohu8.com/highlight/detail?id=2583509672","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583509672?lang=en_us&edition=fundamental","pubTime":"2025-11-14 21:19","pubTimestamp":1763126382,"startTime":"0","endTime":"0","summary":"BUZZ-Septerna rises after Wells Fargo upgrades to 'overweight'** Shares of drug developer Septerna  SEPN.O up ~2% at $19.55 premarket ** Wells Fargo upgrades stock to \"overweight\" from \"equal weight,\" PT to $28 from $18** Brokerage says it is confident on co's SEP-479's  safety profile, differentiation relative to co's prior program** SEPN's study conducted on cynomolgus monkeys  for compound called SEP-479 will prove it does not have bilirubin issues compared to previous drug SEP-786, which showed increase in bilirubin levels, brokerage says** Wells Fargo says phase 1 results for co's SEP-631 compound will be important near-term catalyst, alongside SEP-479 compound coming out in late 2026** As of last close, stock down ~16%, YTD   ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251114:nL6N3WQ0PS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"gpt_icon":0},{"id":"2583508770","title":"Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN), Applied Materials (AMAT) and Nvidia (NVDA)","url":"https://stock-news.laohu8.com/highlight/detail?id=2583508770","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583508770?lang=en_us&edition=fundamental","pubTime":"2025-11-14 19:50","pubTimestamp":1763121055,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Technology sector as 3 analysts just weighed in on Septerna, Inc. (SEPN – Research Report), Applied Mat...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-septerna-inc-sepn-applied-materials-amat-and-nvidia-nvda-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-septerna-inc-sepn-applied-materials-amat-and-nvidia-nvda-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["AMAT","LU0211327993.USD","SEPN","LU1821325948.USD","LU1551013425.SGD","ARKG","NVDY","LU1323610961.USD","NVDS","2NVD.UK","IE00BMPRXN33.USD","NVIW.SI","LU0048584097.USD","NVDA","LU1989763005.USD","IE0034235303.USD","LU1935043023.USD","IE00B4JS1V06.HKD","LU1989772923.USD","LU2860962120.EUR","3NVD.UK","LU0672654240.SGD","LU1244550577.SGD","NVD","NVDX","SNVD.UK","IE00BSNM7G36.USD","LU1989764748.USD","LU1917777945.USD","NVDS.UK","NVDU","IE00BWXC8680.SGD","LU0444973449.USD","BK4529","NVDD","NVD3.UK","LU1989764664.SGD","NVD2.UK","SGXZ81514606.USD","LU1551013342.USD","LU1992135399.USD","LU2271345857.HKD","LU0786609619.USD","LU0211328371.USD","LU1823568750.SGD","LU1084165304.USD","BK4567","BK4007","LU1242518857.USD"],"gpt_icon":0},{"id":"2583508558","title":"Shares of Septerna up 1.7% Premarket After Wells Fargo Raises to 'Overweight' From 'Equal Weight'","url":"https://stock-news.laohu8.com/highlight/detail?id=2583508558","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583508558?lang=en_us&edition=fundamental","pubTime":"2025-11-14 19:43","pubTimestamp":1763120633,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251114:nL4N3WQ0YB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","SEPN"],"gpt_icon":0},{"id":"2583887508","title":"GFL Environmental Inc. : Wells Fargo Initiates Coverage With Overweight Rating; Target Price C$68","url":"https://stock-news.laohu8.com/highlight/detail?id=2583887508","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583887508?lang=en_us&edition=fundamental","pubTime":"2025-11-14 19:32","pubTimestamp":1763119979,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251114:nAZN4QSGE1:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SEPN","BK4007"],"gpt_icon":0},{"id":"2583570476","title":"Septerna, Inc. : Wells Fargo Raises to Overweight From Equal Weight","url":"https://stock-news.laohu8.com/highlight/detail?id=2583570476","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583570476?lang=en_us&edition=fundamental","pubTime":"2025-11-14 19:32","pubTimestamp":1763119974,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251114:nAZN4QSGF9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","SEPN"],"gpt_icon":0},{"id":"2583957730","title":"Wells Fargo Upgrades Septerna to Overweight From Equalweight, Adjusts Price Target to $28 From $18","url":"https://stock-news.laohu8.com/highlight/detail?id=2583957730","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583957730?lang=en_us&edition=fundamental","pubTime":"2025-11-14 18:56","pubTimestamp":1763117813,"startTime":"0","endTime":"0","summary":"Wells Fargo Upgrades Septerna to Overweight From Equalweight, Adjusts Price Target to $28 From $18","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN"],"gpt_icon":0},{"id":"2583541524","title":"Septerna SVP Daniel D. Long Reports Sale of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2583541524","media":"Reuters","labels":["shareholding","insiderTrades","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583541524?lang=en_us&edition=fundamental","pubTime":"2025-11-14 09:13","pubTimestamp":1763082829,"startTime":"0","endTime":"0","summary":"Daniel D. Long, SVP, Drug Discovery at Septerna Inc., reported a disposal of common shares of Septerna Inc. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Septerna Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on November 13, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251114:nNDL74Km9W:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Daniel D. Long Reports Sale of Common Shares","news_tag":"shareholding,insiderTrades,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"gpt_icon":0},{"id":"1188360164","title":"Stock Track | Septerna Soars 5.55% as HC Wainwright Raises Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=1188360164","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188360164?lang=en_us&edition=fundamental","pubTime":"2025-11-11 23:06","pubTimestamp":1762873581,"startTime":"0","endTime":"0","summary":"Shares of Septerna, Inc. (SEPN) are soaring 5.55% in intraday trading on Tuesday, following a positive analyst action from HC Wainwright & Co. The significant uptick in the stock price comes as...","market":"nz","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SEPN"],"gpt_icon":0},{"id":"1104435434","title":"Stock Track | Septerna (SEPN) Soars 5.55% as HC Wainwright Maintains Buy Rating and Raises Price Target","url":"https://stock-news.laohu8.com/highlight/detail?id=1104435434","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1104435434?lang=en_us&edition=fundamental","pubTime":"2025-11-11 23:06","pubTimestamp":1762873579,"startTime":"0","endTime":"0","summary":"Shares of Septerna, Inc. (SEPN) are soaring 5.55% in Tuesday's intraday trading session, following positive analyst actions from HC Wainwright & Co. The biotechnology company's stock is gaining...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SEPN"],"gpt_icon":0},{"id":"2582148369","title":"Septerna Is Maintained at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2582148369","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582148369?lang=en_us&edition=fundamental","pubTime":"2025-11-11 20:53","pubTimestamp":1762865580,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 11, 2025 07:53 ET (12:53 GMT)","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"gpt_icon":0},{"id":"2582808565","title":"Analysts Offer Insights on Technology Companies: Lightpath Technologies (LPTH) and Septerna, Inc. (SEPN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2582808565","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582808565?lang=en_us&edition=fundamental","pubTime":"2025-11-10 23:10","pubTimestamp":1762787457,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Technology sector as 2 analysts just weighed in on Lightpath Technologies (LPTH – Research Report) and ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-lightpath-technologies-lpth-and-septerna-inc-sepn-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-technology-companies-lightpath-technologies-lpth-and-septerna-inc-sepn-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LPTH","BK4157","BK4007","SEPN"],"gpt_icon":0},{"id":"2582168876","title":"Septerna Swings to Q3 Earnings, Revenue Rises","url":"https://stock-news.laohu8.com/highlight/detail?id=2582168876","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582168876?lang=en_us&edition=fundamental","pubTime":"2025-11-10 20:38","pubTimestamp":1762778327,"startTime":"0","endTime":"0","summary":"Septerna  reported Q3 net income Monday of $0.18 per diluted share, swinging from a loss of $8.40 a year earlier.Three analysts polled by FactSet expected EPS of $0.12.Revenue for the quarter ended Sept. 30 was $21.5 million, up from $176,000 a year earlier.Three analysts surveyed by FactSet expected $91.7 million.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN"],"gpt_icon":0},{"id":"2582736658","title":"Septerna Reports Q3 Cash Position of $561.6 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2582736658","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582736658?lang=en_us&edition=fundamental","pubTime":"2025-11-10 20:01","pubTimestamp":1762776086,"startTime":"0","endTime":"0","summary":"Septerna Inc. reported revenue of $21.5 million for the quarter ended September 30, 2025, up from $0.2 million in the same period in 2024. The increase reflects the amortization of $12.8 million from a $195.0 million upfront payment received from Novo Nordisk in July 2025, along with $8.5 million from research services related to the Novo Nordisk collaboration. Research and development expenses rose to $24.3 million from $17.8 million, while general and administrative expenses increased to $7.1 million from $4.9 million year-over-year. The company posted a net income of $8.2 million for the quarter, compared to a net loss of $20.5 million in the prior year period. Cash, cash equivalents, and marketable securities totaled $561.6 million as of September 30, 2025. Business developments include the commencement of a global collaboration and license agreement with Novo Nordisk for the development of oral small-molecule therapies for obesity, type 2 diabetes, and other cardiometabolic diseas","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL68cXc1:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0314104364.USD","BK4585","BK4112","BK4007","LU2210149790.SGD","IE00B64PRP62.GBP","LU2095319765.USD","IE00B3QW5Z07.USD","BK4588","LU2210150020.SGD","NDAQ","IE00BKPKM429.USD","SEPN","IE00BGHQF748.EUR"],"gpt_icon":0},{"id":"2582873987","title":"Press Release: Septerna Highlights Company Progress and Reports Third Quarter 2025 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2582873987","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582873987?lang=en_us&edition=fundamental","pubTime":"2025-11-10 20:00","pubTimestamp":1762776000,"startTime":"0","endTime":"0","summary":"SEP-631  Phase 1 Clinical Trial in Healthy Volunteers Ongoing. Robust Financial Position of $561.6 Million Expected to Support Operations at Least into 2029. SOUTH SAN FRANCISCO, Calif., Nov. 10, 2025  -- Septerna, Inc. , a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor  drug discovery, today highlighted key business updates and upcoming milestones and reported financial results for the quarter ended September 30, 2025.\"In the third quarter, we made meaningful progress across our portfolio, highlighted by the selection of SEP-479 as our next-generation PTH1R agonist development candidate for hypoparathyroidism and the initiation of our Phase 1 clinical trial for SEP-631 which targets MRGPRX2 for mast cell-driven diseases,\" said Jeffrey Finer, M.D., Ph.D., chief executive officer and co-founder of Septerna. \"Both programs exemplify the power of our Native Complex Platform to generate differentiated oral small-molecule GPCR therapies with the pote","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GPCR","BK4099","BK4097","LU2065732104.USD","03160","BK4604","BK4585","TM","BK4599","BK4555","SEPN","BK4588","BK4007","PRGS"],"gpt_icon":0},{"id":"2580213168","title":"Septerna to Participate in Upcoming Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2580213168","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2580213168?lang=en_us&edition=fundamental","pubTime":"2025-11-03 21:00","pubTimestamp":1762174800,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif., Nov.  03, 2025  (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug di","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/11/03/3179226/0/en/Septerna-to-Participate-in-Upcoming-Investor-Conferences.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4599","GPCR","SEPN","BK4007"],"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":1,"totalSize":44,"code":"91000000","status":"200"}]}}