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Sionna Therapeutics

42.19

-0.5700-1.33%

Volume:40.55K

Turnover:1.73M

Market Cap:1.88B

PE:-17.87

High:43.71

Open:43.05

Low:41.97

Close:42.76

52wk High:45.00

52wk Low:7.26

Shares:44.63M

Float Shares:12.61M

Volume Ratio:1.06

T/O Rate:0.32%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.3604

EPS(LYR):-15.9861

ROE:-28.07%

ROA:-19.45%

PB:5.85

PE(LYR):-2.64

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News

Chief Legal Officer Jennifer Fitzpatrick Reports Disposal of Sionna Therapeutics Inc. Common Shares

Sionna Therapeutics Valuation Topping $2 Billion Is 'Too Optimistic', RBC Says

MT Newswires Live

Sionna Therapeutics Shares Lower After RBC Downgrade

MT Newswires Live

Sionna Therapeutics Cut to Underperform From Sector Perform by RBC Capital

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Legal Officer Jennifer Fitzpatrick Reports Disposal of Sionna Therapeutics Inc. 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Sionna Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on December 09, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251209:nNDL7T1rjs:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Chief Legal Officer Jennifer Fitzpatrick Reports Disposal of Sionna Therapeutics Inc. 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Sionna on Monday to underperform from sector perform triggered \"significant feedback,\" according to the report.Sionna is developing small-molecule drugs designed to work alongside Vertex's widely used therapy Trikafta, aiming to improve outcomes for cystic fibrosis patients, the report said.RBC cited variability in Sionna's human bronchial epithelial assays, where Trikafta's performance appeared weaker than in Vertex's published studies, raising questions about the reliability of Sionna's comparisons and the likelihood of clinical benefit.Despite investor pushback, RBC 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