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Summit Therapeutics PLC

16.58

-0.6800-3.94%

Post-market: 16.43-0.1541-0.93%19:59 EDT

Volume:2.08M

Turnover:34.71M

Market Cap:12.86B

PE:-11.51

High:17.51

Open:17.40

Low:16.38

Close:17.26

52wk High:36.91

52wk Low:13.83

Shares:775.37M

Float Shares:129.00M

Volume Ratio:0.59

T/O Rate:1.61%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.4400

EPS(LYR):-1.4439

ROE:-206.10%

ROA:-115.28%

PB:19.51

PE(LYR):-11.48

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News

Summit Therapeutics Links Ivonescimab Brain Metastases Data To November PDUFA

Simply Wall St.

Summit Therapeutics presents HARMONi intracranial efficacy findings for ivonescimab plus chemotherapy in EGFR-mutated NSCLC; intracranial PFS HR narrows to 0.53 in patients with baseline brain metastases

Summit Therapeutics releases HARMONi Phase 3 ivonescimab HRQoL presentation; trial enrollment totals 438 patients

Summit Therapeutics to present multiple ivonescimab data sets at ELCC 2026

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FDA...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-smmt/summit-therapeutics/news/summit-therapeutics-links-ivonescimab-brain-metastases-data","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-smmt/summit-therapeutics/news/summit-therapeutics-links-ivonescimab-brain-metastases-data","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SMMT","SMMF","BK4539","BK4007","BK4139","LU2488822045.USD","LENZ","BK4211"],"gpt_icon":0},{"id":"2622879571","title":"Summit Therapeutics presents HARMONi intracranial efficacy findings for ivonescimab plus chemotherapy in EGFR-mutated NSCLC; intracranial PFS HR narrows to 0.53 in patients with baseline brain metastases","url":"https://stock-news.laohu8.com/highlight/detail?id=2622879571","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622879571?lang=en_us&edition=fundamental","pubTime":"2026-03-28 00:25","pubTimestamp":1774628756,"startTime":"0","endTime":"0","summary":"Summit Therapeutics presents HARMONi intracranial efficacy findings for ivonescimab plus chemotherapy in EGFR-mutated NSCLC; intracranial PFS HR narrows to 0.53 in patients with baseline brain metastases. Summit Therapeutics published a medical research presentation on intracranial efficacy of ivonescimab plus chemotherapy in EGFR-mutated non-squamous NSCLC after progression on a third-generation EGFR-TKI.The document describes HARMONi as a global, randomized, double-blind phase 3 trial comparing ivonescimab plus pemetrexed and carboplatin with placebo plus the same chemotherapy in 438 patients.In a prespecified exploratory analysis, median intracranial PFS in patients with baseline brain metastases was 10.1 months with ivonescimab plus chemotherapy versus 6.5 months with placebo plus chemotherapy.For patients without baseline brain metastases, median intracranial PFS was 15.7 months with ivonescimab plus chemotherapy versus 11.6 months with placebo plus chemotherapy.Disclaimer: This n","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260327:nNDL1SQJqt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LU2488822045.USD","SMMT"],"gpt_icon":0},{"id":"2622879575","title":"Summit Therapeutics releases HARMONi Phase 3 ivonescimab HRQoL presentation; trial enrollment totals 438 patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2622879575","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622879575?lang=en_us&edition=fundamental","pubTime":"2026-03-28 00:25","pubTimestamp":1774628745,"startTime":"0","endTime":"0","summary":"Summit published a medical research poster on health-related quality of life results from the phase 3 HARMONi trial evaluating ivonescimab plus chemotherapy versus placebo plus chemotherapy in previously treated EGFR-mutant non-squamous NSCLC.The randomized study enrolled 438 patients, split 1:1 between treatment arms.Median time to deterioration in EORTC QLQ-C30 global health status/quality of life was 7.0 months with ivonescimab plus chemotherapy versus 6.5 months with placebo plus chemotherapy.Quality-of-life analyses reported no statistically significant or clinically meaningful differences between arms across EORTC QLQ-C30 subscales through cycle 15.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Summit Therapeutics Inc. published","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260327:nNDLc45BmD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2488822045.USD","BK4139","SMMT"],"gpt_icon":0},{"id":"2622829184","title":"Summit Therapeutics to present multiple ivonescimab data sets at ELCC 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2622829184","media":"TIPRANKS","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622829184?lang=en_us&edition=fundamental","pubTime":"2026-03-27 20:21","pubTimestamp":1774614098,"startTime":"0","endTime":"0","summary":"Summit Therapeutics (SMMT) announced that data for its novel, potential first-in-class investigational bispecific antibody, ivonescimab, will be pr...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-to-present-multiple-ivonescimab-data-sets-at-elcc-2026-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-to-present-multiple-ivonescimab-data-sets-at-elcc-2026-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4007","BK4539","BK4211","SMMT","LU2488822045.USD","SMMF","LENZ"],"gpt_icon":0}],"pageSize":4,"totalPage":31,"pageCount":1,"totalSize":124,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/SMMT\",params:#limit:6,delay:false,,,undefined,":[]}}