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While broader market movements were influenced by economic data such as a weaker GDP report causing mixed market reactions, Summit's trajectory appeared to remain robust. The company's specific developments, if relevant, appeared aligned with or enhanced the overall upward market trends, otherwise they added weight to the broader moves observed in the market. Despite market volatility affecting big tech stocks, Summit's performance is indicative of a resilient interest in its shares over the measured period.We've spotted 3 risks for Summit Therapeutics you should be aware of, and 1 of them doesn't sit too well with us.NasdaqGM:SMMT Earnings Per Share Growth as at Apr 2025. Over a three-year span, Summit Therapeutics' shareholders experienced a very large total return of 1517.81%, reflecting significant long-term share price appreciation. 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In its submission to regulators, Akeso included data on patient survival, disclosing that an interim analysis following 157 patient deaths found that participants on ivonescimab had a roughly 22% reduced risk of death, with a hazard ratio of 0.784, a company spokesperson confirmed to STAT. That finding is not statistically significant, but it does meet market analyst expectations, according to Wosen. In an email to STAT, an Akeso spokesperson noted that the interim analysis was not powered for statistical significance and that the company plans to conduct formal analyses of survival once 232 and 280 deaths have occurred in the trial. Shares of Summit Therapeutics fell 37% to $23.21 following the report before halting for news. 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