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Summit Therapeutics PLC

13.81

+0.05000.36%

Post-market: 13.830.0200+0.14%19:05 EDT

Volume:2.84M

Turnover:39.23M

Market Cap:10.71B

PE:-8.67

High:14.08

Open:13.46

Low:13.36

Close:13.76

52wk High:30.98

52wk Low:12.55

Shares:775.37M

Float Shares:130.76M

Volume Ratio:0.93

T/O Rate:2.17%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.5932

EPS(LYR):-1.4439

ROE:-270.95%

ROA:-148.15%

PB:19.61

PE(LYR):-9.56

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Overview Company News Filings

Summit drops as concerns over older patients cloud cancer trial data

Analysts Have Conflicting Sentiments on These Healthcare Companies: Summit Therapeutics (SMMT), Oculis Holding (OCS) and Cogent Biosciences (COGT)

Summit Therapeutics Shares Rise 4.1% Premarket After Co's Lung Cancer Drug With China-Based Partner Shows 15% Higher Survival Rate Than Rival's

THOMSON REUTERS

Summit Therapeutics Says Ivonescimab Improves Survival Over Tislelizumab in Phase III Lung Cancer Trial

MT Newswires Live

Stock Track | Summit Therapeutics Soars 9.06% in Pre-market on Positive Lung Cancer Drug Trial Results

Stock Track | Summit Therapeutics Soars 11.46% on Positive Ivonescimab Lung Cancer Trial Results

Summit Therapeutics posts HARMONi-6 ASCO 2026 plenary slides on ivonescimab in squamous NSCLC

Summit Therapeutics announces OS results from Phase 3 HARMONi-6 trial

Summit Therapeutics presents new results from AK112-206 trial

CORRECTED-Akeso lung cancer drug helps patients live 15% longer than immunotherapy in China trial (May 31)

BioNTech's Cancer Pipeline Seen Strengthening Ahead of Key Trial Results, UBS Says

MT Newswires Live

Assessing Summit Therapeutics (SMMT) Valuation As Ivonescimab Development Draws Fresh Investor Attention

Simply Wall St.

Summit Therapeutics Downgraded by H.C. Wainwright Amid Merck ADC Data Concerns

This Summit Therapeutics Analyst Is No Longer Bullish; Here Are Top 2 Downgrades For Friday

S&P 500 Futures Climb In Premarket Trading; WR Berkley, Summit Therapeutics Lag

Summit Therapeutics Plc : H.c. Wainwright Cuts to Neutral From Buy

THOMSON REUTERS

U.S. RESEARCH ROUNDUP-Jazz Pharmaceuticals, Target, Workday

Used EV sales soar as drivers look to curb fuel costs

Summit Therapeutics (SMMT) Is Down 20.1% After Q1 2026 Net Loss Widens Sharply

Simply Wall St.

Stock Track | Summit Therapeutics Plummets 5.01% Intraday as H.C. Wainwright Cuts Target Price Amid Clinical Data Concerns

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June 1  - Shares of Summit Therapeutics SMMT.O fell 11%, reversing premarket gains as concerns over weaker overall survival benefits in older patients outweighed strong late-stage trial results for its experimental lung cancer drug.In a head-to-head study conducted in China, patients with advanced squamous non-small cell lung cancer who received ivonescimab and chemotherapy lived an average of 27.9 months, compared with 23.7 months for those who received Tevimbra and chemotherapy.At first glance, the trial data was a hit with the \"overall survival data clearing even the highest investor expectations,\" said Evercore analyst Cory Kasimov.At least three brokerages, however, flagged concerns around ivonescimab's efficacy across ages after the trial data — presented at the American Society of Clinical Oncology meeting in Chicago by 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Have Conflicting Sentiments on These Healthcare Companies: Summit Therapeutics (SMMT), Oculis Holding (OCS) and Cogent Biosciences (COGT)","url":"https://stock-news.laohu8.com/highlight/detail?id=2640955116","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640955116?lang=en_us&edition=fundamental","pubTime":"2026-06-01 19:00","pubTimestamp":1780311651,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on Summit Therapeutics (SMMT), Oculis Holding (OCS) 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Therapeutics Shares Rise 4.1% Premarket After Co's Lung Cancer Drug With China-Based Partner Shows 15% Higher Survival Rate Than Rival's","url":"https://stock-news.laohu8.com/highlight/detail?id=2640953552","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640953552?lang=en_us&edition=fundamental","pubTime":"2026-06-01 18:26","pubTimestamp":1780309615,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nFWN4290BG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SMMT","LU2488822045.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640932307","title":"Summit Therapeutics Says Ivonescimab Improves Survival Over Tislelizumab in Phase III Lung Cancer Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2640932307","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640932307?lang=en_us&edition=fundamental","pubTime":"2026-06-01 16:43","pubTimestamp":1780303423,"startTime":"0","endTime":"0","summary":"Summit Therapeutics'  ivonescimab in combination with chemotherapy demonstrated a significant overall survival benefit over tislelizumab plus chemotherapy in the Phase III HARMONi-6 trial in previously untreated patients with advanced squamous non-small cell lung cancer, the company said Sunday.The company said ivonescimab reduced the risk of death by 34%, with patients receiving the drug plus chemotherapy achieving longer median overall survival and higher 24-month survival rates than those treated with tislelizumab plus chemotherapy.The survival benefit was consistent across both PD-L1-negative and PD-L1-positive patient groups. The study had previously met its primary endpoint of progression-free survival, the company added.The China-based trial, led by Akeso, showed no new safety concerns. Results were presented at the 2026 American Society of Clinical Oncology Annual Meeting and published in The Lancet.Summit Therapeutics shares were up over 4% in Monday premarket activity.Price: ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU2488822045.USD","BK4134","BK4139","BK4539","SMMF","BK4211","III","LENZ","SMMT","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1158873376","title":"Stock Track | Summit Therapeutics Soars 9.06% in Pre-market on Positive Lung Cancer Drug Trial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=1158873376","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1158873376?lang=en_us&edition=fundamental","pubTime":"2026-06-01 16:05","pubTimestamp":1780301109,"startTime":"0","endTime":"0","summary":"Summit Therapeutics PLC (SMMT) stock soared 9.06% in pre-market trading on Monday, reflecting significant investor optimism following a major clinical development announcement.The sharp increase is...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SMMT"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1128280885","title":"Stock Track | Summit Therapeutics Soars 11.46% on Positive Ivonescimab Lung Cancer Trial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=1128280885","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1128280885?lang=en_us&edition=fundamental","pubTime":"2026-06-01 15:35","pubTimestamp":1780299350,"startTime":"0","endTime":"0","summary":"Summit Therapeutics PLC (SMMT) experienced a significant surge of 11.46% in pre-market trading on Monday, following the release of promising clinical trial data for its investigational drug...","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["SMMT"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640985932","title":"Summit Therapeutics posts HARMONi-6 ASCO 2026 plenary slides on ivonescimab in squamous NSCLC","url":"https://stock-news.laohu8.com/highlight/detail?id=2640985932","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640985932?lang=en_us&edition=fundamental","pubTime":"2026-06-01 03:34","pubTimestamp":1780256051,"startTime":"0","endTime":"0","summary":"Summit Therapeutics published Phase 3 HARMONi-6 overall survival results for ivonescimab with chemotherapy in first-line advanced squamous NSCLC.Ivonescimab, a PD-1/VEGF bispecific antibody, showed a significant overall survival benefit versus tislelizumab with chemotherapy.Earlier interim data showed median PFS of 11.1 months versus 6.9 months; HR 0.60; p<0.0001.The double-blind trial enrolled 532 patients, testing ivonescimab 20 mg/kg every three weeks versus tislelizumab 200 mg every three weeks.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Summit Therapeutics Inc. published the original content used to generate this news brief on May 31, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260531:nNDL7tgQ9S:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2488822045.USD","BK4139","SMMT"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639882889","title":"Summit Therapeutics announces OS results from Phase 3 HARMONi-6 trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2639882889","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639882889?lang=en_us&edition=fundamental","pubTime":"2026-05-31 21:50","pubTimestamp":1780235405,"startTime":"0","endTime":"0","summary":"Summit Therapeutics (SMMT) announced overall survival, OS, results from the Phase III HARMONi-6 trial, conducted in China and sponsored by Summit’s...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-announces-os-results-from-phase-3-harmoni-6-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-announces-os-results-from-phase-3-harmoni-6-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4211","LENZ","BK4007","BK4139","BK4539","SMMF","SMMT","LU2488822045.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639884389","title":"Summit Therapeutics presents new results from AK112-206 trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2639884389","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639884389?lang=en_us&edition=fundamental","pubTime":"2026-05-31 21:35","pubTimestamp":1780234551,"startTime":"0","endTime":"0","summary":"Summit Therapeutics (SMMT) presented new results from the AK112-206 trial, a global, open-label, multicenter Phase II study in first-line metastati...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-presents-new-results-from-ak112-206-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/summit-therapeutics-presents-new-results-from-ak112-206-trial-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4539","SMMF","LENZ","LU2488822045.USD","BK4211","BK4007","SMMT","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2639398853","title":"CORRECTED-Akeso lung cancer drug helps patients live 15% longer than immunotherapy in China trial (May 31)","url":"https://stock-news.laohu8.com/highlight/detail?id=2639398853","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2639398853?lang=en_us&edition=fundamental","pubTime":"2026-05-31 20:00","pubTimestamp":1780228800,"startTime":"0","endTime":"0","summary":"CORRECTED-Akeso lung cancer drug helps patients live 15% longer than immunotherapy in China trial Corrects executive designation in paragraph 6 to \"chief medical officer\" from \"chief scientific officer\"Ivonescimab combo cut risk of death by 34% versus TevimbraAkeso touts ivonescimab as a potential new standard of care for patientsGlobal trial comparing ivonescimab to Keytruda expected to aid US approvalBy Mariam Sunny and Kamal Choudhury","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260531:nL4N4230Q4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0348767384.USD","LU1267930573.SGD","SG9999002232.USD","LU0310800379.SGD","LU2357627491.SGD","LU0861579265.USD","LU0980610538.SGD","LU1037948541.HKD","LU1929549753.HKD","LU2491049909.HKD","LU2361044865.SGD","BK4550","LU2361044949.HKD","LU1162221912.USD","LU2468319806.SGD","HCA","IE00BJJMRZ35.SGD","LU1934455277.USD","09926","LU1923622614.USD","LU2125154935.USD","LU2433249047.HKD","LU0348825331.USD","LU0265550359.USD","MRK","LU1119994496.HKD","LU0432979614.USD","LU0128525929.USD","LU0348784397.USD","LU1261432733.SGD","LU1989772923.USD","IE0002141913.USD","IE00B4R5TH58.HKD","IE00BLSP4239.USD","LU0965509010.AUD","LU0965509101.SGD","BK4139","LU0882574055.USD","LU2244417387.USD","IE0009355771.USD","SG9999014021.USD","SG9999002224.SGD","IE00BPRC5H50.USD","688235","SG9999014039.USD","SMMT","LU1023059063.AUD","LU1069347547.HKD","IE00BN8TJ469.HKD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2638680853","title":"BioNTech's 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Securiti","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4535","SMMT","BK4548","BK4585","BK4139","LU2488822045.USD","BK4568","BK4551","BK4588","BNTX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637330853","title":"Assessing Summit Therapeutics (SMMT) Valuation As Ivonescimab Development Draws Fresh Investor Attention","url":"https://stock-news.laohu8.com/highlight/detail?id=2637330853","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637330853?lang=en_us&edition=fundamental","pubTime":"2026-05-24 15:30","pubTimestamp":1779607807,"startTime":"0","endTime":"0","summary":"Summit Therapeutics (SMMT) is drawing fresh attention as investors focus on ivonescimab, its bispecific antibody candidate for non-small cell lung cancer and colorectal cancer, and what this could mean for the stock.\nSee our latest analysis for Summit Therapeutics.\nAt a recent share price of US$16.62, Summit Therapeutics has seen its 1 month share price return fall 24.73%, even though its 3 month share price return is up 3.29% and the 3 year total shareholder return is roughly 9x. This...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-smmt/summit-therapeutics/news/assessing-summit-therapeutics-smmt-valuation-as-ivonescimab","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-smmt/summit-therapeutics/news/assessing-summit-therapeutics-smmt-valuation-as-ivonescimab","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LU2488822045.USD","SMMT","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1191940716","title":"Summit Therapeutics Downgraded by H.C. Wainwright Amid Merck ADC Data Concerns","url":"https://stock-news.laohu8.com/highlight/detail?id=1191940716","media":"Deep News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1191940716?lang=en_us&edition=fundamental","pubTime":"2026-05-23 03:51","pubTimestamp":1779479475,"startTime":"0","endTime":"0","summary":"H.C. Wainwright downgraded Summit Therapeutics PLC's stock rating from Buy to Neutral on May 22, removing its prior $23 price target. This action was prompted by positive Phase III data for sac-TMT,...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SMMT","LU2488822045.USD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637088346","title":"This Summit Therapeutics Analyst Is No Longer Bullish; Here Are Top 2 Downgrades For Friday","url":"https://stock-news.laohu8.com/highlight/detail?id=2637088346","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637088346?lang=en_us&edition=fundamental","pubTime":"2026-05-23 01:04","pubTimestamp":1779469440,"startTime":"0","endTime":"0","summary":"Analysts changed outlook on top names, including SMMT, DAVA. See what others think before buying SMMT stock.","market":"us","thumbnail":"https://cdn.benzinga.com/cdn-cgi/image/width=260,dpr=2,format=auto,quality=85/files/images/story/2026/05/22/Analyst-Woman-Working-With-Information-D.jpeg","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/cdn-cgi/image/width=260,dpr=2,format=auto,quality=85/files/images/story/2026/05/22/Analyst-Woman-Working-With-Information-D.jpeg"],"rights":{"source":"benzinga_hot_news","url":"https://www.benzinga.com/analyst-stock-ratings/initiation/26/05/52751764/this-summit-therapeutics-analyst-is-no-longer-bullish-here-are-top-2-downgrades-for-friday","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/analyst-stock-ratings/initiation/26/05/52751764/this-summit-therapeutics-analyst-is-no-longer-bullish-here-are-top-2-downgrades-for-friday","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_hot_news","symbols":["SMMT","LU2488822045.USD","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637319349","title":"S&P 500 Futures Climb In Premarket Trading; WR Berkley, Summit Therapeutics Lag","url":"https://stock-news.laohu8.com/highlight/detail?id=2637319349","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637319349?lang=en_us&edition=fundamental","pubTime":"2026-05-22 19:30","pubTimestamp":1779449400,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Barrons.com using technology from Automated Insights.With U.S. stock markets set to open in two hours, Estee Lauder Cos. Cl A  was up 10.3% in pre-market trading, and TTM Technologies Inc.  was up 8.3%.Workday Inc. Cl A , Kodiak Gas Services Inc. , and Zoom Communications Inc.  were all posting gains of at least 7%. In early trading, W.R. Berkley Corp.  and Summit Therapeutics Inc.  had posted declines, falling 32.2% and 9.0%, respectively.Meanwhile S&P 500 futures were up 0.10%, with futures for the Dow Jones Industrial Average rising 0.29%. The Cboe Volatility Index futures were down 3.00%.In commodities news, Brent crude oil futures were up 2.87%, and gold futures were down 0.63%. Bitcoin fell 0.58% to $77,159.In afternoon trading, stocks in Europe are up, with the STOXX Europe 600 Index climbing 0.41% and the FTSE 100 Index climbing 0.22% from the previous close.U.S. stock markets open for trading at 9:30 a.m. ET.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ETFT","ALLW","SH","LU1804176565.USD","UPRO","LU0082616367.USD","BK4505","IE0004445239.USD","SMAX","SFY","SPYD","SPXL","SPUU","EL","BK4139","LU1046421795.USD","IVW","SCHX","IE00B5949003.HKD","SPDN","RSPA","DBSC","LU2265009873.SGD","LU1988902786.USD","BK4585","LU2404859667.USD","SMMT","HIBL","LU1935043536.SGD","LU0757428866.USD","YSPY","NOBL","IVE","LU2552382132.HKD","LU2488822045.USD","LU0690374961.EUR","IE0031619046.USD","ITOT","LU1989773731.SGD","IJH","XDTE","XLG","BK4183","SPMO","BK4613","SPHQ","SPYH","SDS","BK4548","LU1861558580.USD","BK4023","SPXU",".SPX","ACWI","MOAT","RSP","LU1935042991.SGD","BK4532","LU2517655028.SGD","RSPN","BK4145","HIBS","SSO","IVV","SPYV","LU2517655374.HKD","LU0690374615.EUR","IJR","MMAX","SPHD","LU2517655291.USD","VTV","BK4179","BMAY","XYLD","LU1691799644.USD","SCHB","LU1064131342.USD","JEPI","BK4528","LU1989763005.USD","SPXS","VBK","GPIX","LU2264538146.SGD","LU1235294995.USD","BK4504","BK4512","WRB","BK4588","KGS","LU2552382215.SGD","ZM","BK4533","IE00B19Z4B17.USD","LU1861559042.SGD","SPYU","IE00B66KJ199.SGD","RSPU","LU1815336091.USD","LU2552382058.USD","SPGP","SPYQ","SPYG","WDAY","VEU","BK4551","VV","VTI","SPYM","LU0314104364.USD","LU2404859741.USD","LU1823568750.SGD","SPUS","BK4581","BK4535","BK4525","DMAX","IE00B7SZL793.SGD","TSPY","LU0719512351.SGD","BK4107","BK4558","TTMI","BK4554","GSLC","SPLV","IE0009356076.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637313509","title":"Summit Therapeutics Plc : H.c. 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