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They were followed by pharmaceutical company Novo Nordisk  and consumer goods company Unilever , which were up 1.7% and 0.3% respectively.The decliners from continental Europe were led by financial services companies Banco Santander  and Banco Bilbao Vizcaya Argentaria , which fell 4.4% and 2.6% respectively. They were followed by internet browser company Opera , which dropped 3.3%, and 3D printer company Materialise  down 2.3%.From the UK and Ireland, the gainers were led by  biopharmaceutical company NuCana , which rose 6.3%, and medical device maker Smith & Nephew , up 4%. 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Under the Agreement, Smith+Nephew will market and sell CENTRIO Platelet-Rich Plasma System, their own branded version of Nuo’s underlying Aurix System to the United States wound care market. Nuo will continue to be responsible for manufacturing the product. The Aurix product brand sold separately by Nuo will remain in the market under Nuo’s full control and will be fully available commercially subject to certain customer overlap conditions more fully addressed in the Agreement.In exchange for Smith+Nephew’s exclusive distribution rights for CENTRIO over the initial term of five years, Nuo has received an upfront distribution fee, and will 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