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Spruce Biosciences, Inc.

89.20

+6.097.33%

Post-market: 88.00-1.2000-1.35%19:19 EST

Volume:108.69K

Turnover:9.62M

Market Cap:95.06M

PE:-1.05

High:92.42

Open:87.57

Low:83.12

Close:83.11

52wk High:240.00

52wk Low:4.28

Shares:1.07M

Float Shares:877.30K

Volume Ratio:0.63

T/O Rate:12.39%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-84.7510

EPS(LYR):-96.3944

ROE:-167.93%

ROA:-76.92%

PB:17.65

PE(LYR):-0.93

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Overview Company News Filings

Spruce Shares Fall on $50M Private Placement

BRIEF-Spruce Biosciences Announces $50.0 Million Private Placement Financing

Spruce Biosciences Announces $50 Million Private Placement to Advance Sanfilippo Syndrome Therapy

Spruce Biosciences Stock Extends 2,900% Rally after FDA Fast Track Ignites Investor Frenzy

This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug

Spruce Biosciences Shares Jump 88% Premarket After Over 1,300% Surge in Previous Session

THOMSON REUTERS

Why Spruce Biosciences Stock (SPRB) Soared over 1,300% in a Stunning Rally

Spruce Biosciences (SPRB) Stock Jumps 30% After Hours Following Red Hot Rally On Monday: Here's Why

Benzinga_recent_news

Spruce Biosciences Stock Is Soaring Today: Here's Why

Benzinga_recent_news

SPRUCE BIOSCIENCES, INC. trading resumes

BUZZ-Spruce Biosciences soars after FDA's 'breakthrough therapy' tag for genetic disorder drug

Spruce Biosciences Secures FDA Breakthrough Therapy Designation for Tralesinidase Alfa in Sanfilippo Syndrome Type B

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (Ta-Ert) in Sanfilippo Syndrome Type B (Mps Iiib)

THOMSON REUTERS

Spruce Biosciences Q2 EPS $(3.50) Beats $(19.13) Estimate

Spruce Biosciences Inc. Anticipates Nasdaq Capital Market Relisting After Meeting Minimum Bid Price Requirement

Spruce Biosciences Announces First Patient Dosed in Phase 2 Trial of Tildacerfont for Major Depressive Disorder, with Results Expected in 1H 2026

Spruce Biosciences Announces Promising Long-Term Data for Tralesinidase Alfa Therapy in Treating Sanfilippo Syndrome Type B

Spruce Biosciences Announces 1-for-75 Reverse Stock Split Effective August 5, 2025

Spruce Biosciences Announces Reverse Stock Split

THOMSON REUTERS

Spruce Biosciences Receives Conditional Approval to Resume Trading on Nasdaq Capital Market

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Shares Fall on $50M Private Placement","url":"https://stock-news.laohu8.com/highlight/detail?id=2573255879","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573255879?lang=en_us&edition=fundamental","pubTime":"2025-10-08 20:39","pubTimestamp":1759927140,"startTime":"0","endTime":"0","summary":"Shares of Spruce Biosciences were lower after the company said it had agreed to sell shares in a private placement expected to raise $50 million in gross proceeds.The stock fell 23% to $140 in premarket trading.The company said it has agreed to sell 502,181 shares of its common stock for $68 apiece while some investors are purchasing pre-funded warrants to buy up to 233,144 shares at $67.99 each. The warrants will be exercisable for five years.The company said it would use the proceeds to advance its treatment of Sanfilippo Syndrome Type B, a rare genetic disorder, through a biologics license application submission in the first quarter of next year and a U.S. commercial launch in late 2026.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRB","BK4139"],"gpt_icon":1},{"id":"2573923305","title":"BRIEF-Spruce Biosciences Announces $50.0 Million Private Placement Financing","url":"https://stock-news.laohu8.com/highlight/detail?id=2573923305","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573923305?lang=en_us&edition=fundamental","pubTime":"2025-10-08 20:18","pubTimestamp":1759925927,"startTime":"0","endTime":"0","summary":"BRIEF-Spruce Biosciences Announces $50.0 Million Private Placement FinancingOct 8 (Reuters) - Spruce Biosciences Inc SPRB.O:SPRUCE BIOSCIENCES ANNOUNCES $50.0 MILLION PRIVATE PLACEMENT FINANCINGSource text: ID:nBw1vSydVaFurther company coverage: SPRB.O ((Reuters.Briefs@thomsonreuters.com;))","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251008:nTUA737PFJ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRB"],"gpt_icon":0},{"id":"2573192849","title":"Spruce Biosciences Announces $50 Million Private Placement to Advance Sanfilippo Syndrome Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2573192849","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573192849?lang=en_us&edition=fundamental","pubTime":"2025-10-08 20:01","pubTimestamp":1759924866,"startTime":"0","endTime":"0","summary":"Spruce Biosciences Inc. , a late-stage biopharmaceutical company, has announced a private placement financing expected to raise approximately $50 million in gross proceeds. The funds will support the advancement of tralesinidase alfa enzyme replacement therapy  for Sanfilippo Syndrome Type B , with plans for a biologics license application submission in early 2026 and a potential U.S. commercial launch later that year. Under the terms of the agreement, investors will purchase around 502,181 shares of Spruce Biosciences' common stock at $68.00 per share. Certain investors will also acquire pre-funded warrants to purchase up to 233,144 shares of common stock at $67.99 per warrant, with an exercise period of five years. Leerink Partners, Citizens Capital Markets, and H.C. Wainwright & Co. are serving as placement agents, and Oppenheimer & Co. is acting as capital markets advisor for the transaction. The private placement is expected to close around October 9, 2025, subject to customary cl","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251008:nNDL3Gn7cx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MNSH","BK4139","OPY","BK4127","BK4207","SPRB"],"gpt_icon":1},{"id":"2573596591","title":"Spruce Biosciences Stock Extends 2,900% Rally after FDA Fast Track Ignites Investor Frenzy","url":"https://stock-news.laohu8.com/highlight/detail?id=2573596591","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573596591?lang=en_us&edition=fundamental","pubTime":"2025-10-07 22:14","pubTimestamp":1759846472,"startTime":"0","endTime":"0","summary":"Spruce Biosciences ($SPRB) is on one of the most dramatic runs in biotech this year. Shares have surged nearly 2,900% over the past week, reaching ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/spruce-biosciences-stock-extends-2900-rally-after-fda-fast-track-ignites-investor-frenzy?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":"a7561b70b4a3f3fb25e92e652f8f7604","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/spruce-biosciences-stock-extends-2900-rally-after-fda-fast-track-ignites-investor-frenzy?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4104","BK4139","FAST","BK4588","IE00BFXG0V08.USD","IE00BYQQ9H92.USD","IE00B5TLWC47.USD","BK4567","SPRB","BK4585"],"gpt_icon":0},{"id":"2573963670","title":"This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2573963670","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573963670?lang=en_us&edition=fundamental","pubTime":"2025-10-07 22:09","pubTimestamp":1759846160,"startTime":"0","endTime":"0","summary":"Shares of the microcap biotech Spruce Biosciences just had their best day on record after it said the Food and Drug Administration had granted it a special designation that would allow its rare-disease drug to move through the review process quicker.The stock rallied 1,378% Monday to close at $121.58 after several trading pauses for volatility. It gained another 51% to $197.50 in early trading Tuesday.While that sounds dramatic, it isn't unheard of among clinical-stage pharma companies. Drugmakers at that stage of development typically don't generate any revenue and operate at a loss as they spend money to develop medicines, making them a risky but potentially hugely rewarding bet for investors.Spruce is focused on therapies for neurological disorders with significant unmet medical need. It is currently developing a treatment of Sanfilippo Syndrome, or MPS IIIB. It is an ultrarare and fatal genetic disease affecting the brain and spinal cord, leading to deteriorating neurological funct","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"a7561b70b4a3f3fb25e92e652f8f7604","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"2","news_top_title":"This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4211","SPRB","BK6045","BK6512","BK4139"],"gpt_icon":0},{"id":"2573795329","title":"Spruce Biosciences Shares Jump 88% Premarket After Over 1,300% Surge in Previous Session","url":"https://stock-news.laohu8.com/highlight/detail?id=2573795329","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573795329?lang=en_us&edition=fundamental","pubTime":"2025-10-07 16:59","pubTimestamp":1759827577,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251007:nL3N3VO0G8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"gpt_icon":0},{"id":"2573958613","title":"Why Spruce Biosciences Stock (SPRB) Soared over 1,300% in a Stunning Rally","url":"https://stock-news.laohu8.com/highlight/detail?id=2573958613","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573958613?lang=en_us&edition=fundamental","pubTime":"2025-10-07 15:55","pubTimestamp":1759823706,"startTime":"0","endTime":"0","summary":"Spruce Biosciences ($SPRB) stock jumped more than 1,378.5% on Monday after the company announced that the U.S. FDA (Food and Drug Administration) g...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/why-spruce-biosciences-stock-sprb-soared-over-1300-in-a-stunning-rally?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/why-spruce-biosciences-stock-sprb-soared-over-1300-in-a-stunning-rally?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","SPRB"],"gpt_icon":0},{"id":"2573307439","title":"Spruce Biosciences (SPRB) Stock Jumps 30% After Hours Following Red Hot Rally On Monday: Here's Why","url":"https://stock-news.laohu8.com/highlight/detail?id=2573307439","media":"Benzinga_recent_news","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573307439?lang=en_us&edition=fundamental","pubTime":"2025-10-07 15:27","pubTimestamp":1759822020,"startTime":"0","endTime":"0","summary":"Spruce Biosciences shares soared after the FDA granted Breakthrough Therapy Designation to its lead treatment for Sanfilippo Syndrome Type B.","market":"us","thumbnail":"https://cdn.benzinga.com/files/images/story/2025/10/07/Scientist-Pipetting-At-A-Biomedical-Labo.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2025/10/07/Scientist-Pipetting-At-A-Biomedical-Labo.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/markets/equities/25/10/48060995/spruce-biosciences-sprb-stock-jumps-30-after-hours-following-red-hot-rally-on-monday-heres-why","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/markets/equities/25/10/48060995/spruce-biosciences-sprb-stock-jumps-30-after-hours-following-red-hot-rally-on-monday-heres-why","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["SPRB","BK4139"],"gpt_icon":1},{"id":"2573601174","title":"Spruce Biosciences Stock Is Soaring Today: Here's Why","url":"https://stock-news.laohu8.com/highlight/detail?id=2573601174","media":"Benzinga_recent_news","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573601174?lang=en_us&edition=fundamental","pubTime":"2025-10-07 00:31","pubTimestamp":1759768260,"startTime":"0","endTime":"0","summary":"Shares of Spruce Biosciences, Inc. (NASDAQ: SPRB) are surging Monday after the biotech company shared an important regulatory update about one of its therapy treatments.","market":"us","thumbnail":"https://cdn.benzinga.com/files/images/story/2025/10/06/Pipette-Adding-Fluid-To-One-Of-Several-T.jpeg?optimize=medium&dpr=2&auto=webp&width=240","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2025/10/06/Pipette-Adding-Fluid-To-One-Of-Several-T.jpeg?optimize=medium&dpr=2&auto=webp&width=240"],"rights":{"source":"benzinga_recent_news","url":"https://www.benzinga.com/trading-ideas/movers/25/10/48049792/spruce-biosciences-stock-is-soaring-today-heres-why","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/trading-ideas/movers/25/10/48049792/spruce-biosciences-stock-is-soaring-today-heres-why","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_recent_news","symbols":["SPRB","BK4139"],"gpt_icon":0},{"id":"2573085086","title":"SPRUCE BIOSCIENCES, INC. trading resumes","url":"https://stock-news.laohu8.com/highlight/detail?id=2573085086","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573085086?lang=en_us&edition=fundamental","pubTime":"2025-10-06 21:41","pubTimestamp":1759758091,"startTime":"0","endTime":"0","summary":"09:36 EDT SPRUCE BIOSCIENCES (SPRB), INC. trading resumes Published first on TheFly – the ultimate source for real-time, market-moving breaking fin...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/spruce-biosciences-inc-trading-resumes-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/spruce-biosciences-inc-trading-resumes-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","SPRB","INC"],"gpt_icon":0},{"id":"2573395672","title":"BUZZ-Spruce Biosciences soars after FDA's 'breakthrough therapy' tag for genetic disorder drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2573395672","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573395672?lang=en_us&edition=fundamental","pubTime":"2025-10-06 20:19","pubTimestamp":1759753187,"startTime":"0","endTime":"0","summary":"BUZZ-Spruce Biosciences soars after FDA's 'breakthrough therapy' tag for genetic disorder drug** Shares of Spruce Biosciences SPRB.O rise 69% to $14.89 premarket** Co says U.S. FDA grants \"breakthrough therapy\" tag for its experimental drug, tralesinidase alfa, to treat Sanfilippo Syndrome Type B** The condition is a genetic disorder that causes progressive brain damage in children** The breakthrough therapy tag is meant to speed up development and review of drugs to treat a serious condition or unmet medical need** Co plans to submit application for U.S. approval in Q1 of 2026** As of last close, stock down 72% YTD  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"98aa5a071838dbc09973453e152cc1ef","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251006:nL3N3VN0MZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRB"],"gpt_icon":1},{"id":"2573458674","title":"Spruce Biosciences Secures FDA Breakthrough Therapy Designation for Tralesinidase Alfa in Sanfilippo Syndrome Type B","url":"https://stock-news.laohu8.com/highlight/detail?id=2573458674","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573458674?lang=en_us&edition=fundamental","pubTime":"2025-10-06 20:01","pubTimestamp":1759752097,"startTime":"0","endTime":"0","summary":"**Spruce Biosciences Receives FDA Breakthrough Therapy Designation for Sanfilippo Syndrome Treatment** Spruce Biosciences, Inc.  announced that the U.S. Food and Drug Administration  has granted Breakthrough Therapy Designation to tralesinidase alfa enzyme replacement therapy  for the treatment of Sanfilippo Syndrome Type B . This designation is intended to expedite the development and regulatory review of promising treatments for serious conditions and is based on preliminary clinical evidence demonstrating TA-ERT's potential to significantly improve patient outcomes. Spruce Biosciences plans to submit a Biologics License Application for TA-ERT in the first quarter of 2026. No other organizations were named as recipients of this regulatory designation.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and sho","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"98aa5a071838dbc09973453e152cc1ef","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251006:nNDL9Mp7Gg:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRB"],"gpt_icon":0},{"id":"2573674917","title":"Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (Ta-Ert) in Sanfilippo Syndrome Type B (Mps Iiib)","url":"https://stock-news.laohu8.com/highlight/detail?id=2573674917","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573674917?lang=en_us&edition=fundamental","pubTime":"2025-10-06 20:00","pubTimestamp":1759752003,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"98aa5a071838dbc09973453e152cc1ef","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251006:nTUA9TCFMY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["SPRB","BK4139"],"gpt_icon":0},{"id":"2559964699","title":"Spruce Biosciences Q2 EPS $(3.50) Beats $(19.13) Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2559964699","media":"Benzinga","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2559964699?lang=en_us&edition=fundamental","pubTime":"2025-08-15 04:28","pubTimestamp":1755203283,"startTime":"0","endTime":"0","summary":"Spruce Biosciences (NASDAQ:SPRB) reported quarterly losses of $(3.50) per share which beat the analyst consensus estimate of $(19.13) by 81.7 percent. This is a 1490.91 percent decrease over losses of $(0.22) per share","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/25/08/47139528/spruce-biosciences-q2-eps-3-50-beats-19-13-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Spruce Biosciences Q2 EPS $(3.50) Beats $(19.13) Estimate","news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRB"],"gpt_icon":0},{"id":"2559648899","title":"Spruce Biosciences Inc. Anticipates Nasdaq Capital Market Relisting After Meeting Minimum Bid Price Requirement","url":"https://stock-news.laohu8.com/highlight/detail?id=2559648899","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2559648899?lang=en_us&edition=fundamental","pubTime":"2025-08-15 04:19","pubTimestamp":1755202785,"startTime":"0","endTime":"0","summary":"Spruce Biosciences, Inc., a late-stage biopharmaceutical company, is anticipating a relisting on the Nasdaq Capital Market. This development follows the company's compliance with a minimum bid price for 20 consecutive trading days. The move is part of Spruce Biosciences' ongoing efforts to enhance its market presence and support its growth initiatives. The company remains focused on advancing its pipeline of novel therapies for neurological disorders, with significant attention on treatments for conditions with unmet medical needs.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250814:nNDL5jf7WL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRBD","BK4139","SPRB"],"gpt_icon":0},{"id":"2559961239","title":"Spruce Biosciences Announces First Patient Dosed in Phase 2 Trial of Tildacerfont for Major Depressive Disorder, with Results Expected in 1H 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2559961239","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2559961239?lang=en_us&edition=fundamental","pubTime":"2025-08-15 04:07","pubTimestamp":1755202064,"startTime":"0","endTime":"0","summary":"Spruce Biosciences Announces First Patient Dosed in Phase 2 Trial of Tildacerfont for Major Depressive Disorder, with Results Expected in 1H 2026. Spruce Biosciences, Inc., a biopharmaceutical company specializing in treatments for neurological disorders, has announced the dosing of the first patient in its Phase 2 TAMARIND trial of Tildacerfont for Major Depressive Disorder . The company anticipates presenting the topline results of this study in the first half of 2026. This trial is part of Spruce Biosciences' ongoing efforts to develop novel therapies for conditions with significant unmet medical needs.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news br","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250814:nNDLbMHqjV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRBD","SPRB","BK4139"],"gpt_icon":0},{"id":"2559694961","title":"Spruce Biosciences Announces Promising Long-Term Data for Tralesinidase Alfa Therapy in Treating Sanfilippo Syndrome Type B","url":"https://stock-news.laohu8.com/highlight/detail?id=2559694961","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2559694961?lang=en_us&edition=fundamental","pubTime":"2025-08-15 04:00","pubTimestamp":1755201617,"startTime":"0","endTime":"0","summary":"Spruce Biosciences Inc. has announced results from a long-term data integration of their tralesinidase alfa enzyme replacement therapy  clinical program, aimed at treating patients with Sanfilippo Syndrome Type B . The study evaluated group-level efficacy data over a five-year period from clinical studies 201, 202, and 401, comparing treated patients with untreated patients from natural history studies 901 and 902. The results demonstrated that cognition and cortical grey matter volume were stabilized in patients treated with TA-ERT, relative to declines observed in untreated patients. Additionally, TA-ERT significantly lowered cerebral spinal fluid heparan-sulfate non-reducing end , identified as a key factor in neurodegeneration associated with MPS IIIB. These findings were presented as part of the company's ongoing efforts to develop and commercialize novel therapies for neurological disorders with significant unmet medical needs.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250814:nNDLc8nSkZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SPRB","SPRBD","BK4139"],"gpt_icon":0},{"id":"2554780747","title":"Spruce Biosciences Announces 1-for-75 Reverse Stock Split Effective August 5, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2554780747","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2554780747?lang=en_us&edition=fundamental","pubTime":"2025-07-25 04:01","pubTimestamp":1753387271,"startTime":"0","endTime":"0","summary":"Spruce Biosciences, Inc.  has announced a 1-for-75 reverse stock split of its common stock, effective August 4, 2025. This move, approved by stockholders, aims to meet Nasdaq Capital Market's minimum bid price requirement. The stock will trade on a split-adjusted basis under the ticker \"SPRB\" starting August 5, 2025. Fractional shares will not be issued; instead, cash payments will be made for fractional entitlements.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news brief via Business Wire  on July 24, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250724:nNDL6pWnlP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SPRB"],"gpt_icon":0},{"id":"2554802297","title":"Spruce Biosciences Announces Reverse Stock Split","url":"https://stock-news.laohu8.com/highlight/detail?id=2554802297","media":"THOMSON REUTERS","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2554802297?lang=en_us&edition=fundamental","pubTime":"2025-07-25 04:01","pubTimestamp":1753387260,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250724:nTUAC4ZW2G:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","SPRB"],"gpt_icon":0},{"id":"2542051997","title":"Spruce Biosciences Receives Conditional Approval to Resume Trading on Nasdaq Capital Market","url":"https://stock-news.laohu8.com/highlight/detail?id=2542051997","media":"Reuters","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2542051997?lang=en_us&edition=fundamental","pubTime":"2025-06-12 20:01","pubTimestamp":1749729678,"startTime":"0","endTime":"0","summary":"Spruce Biosciences Inc. has announced that it has received conditional approval to resume trading on the Nasdaq Capital Market, where its common stock had been temporarily suspended. The trading resumption is contingent upon meeting Nasdaq's minimum bid price requirement by August 5, 2025.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spruce Biosciences Inc. published the original content used to generate this news brief via Business Wire  on June 12, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250612:nNDL2QTRM2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BKPKM429.USD","LU2210150020.SGD","IE00B64PRP62.GBP","SPRB","BK4585","IE00B3QW5Z07.USD","BK4139","BK4588","LU2095319765.USD","LU2210149790.SGD","BK4112","IE00BGHQF748.EUR","NDAQ"],"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":2,"totalSize":41,"code":"91000000","status":"200"}]}}