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Stoke Therapeutics, Inc.

32.44

+0.45001.41%

Pre-market: 32.40-0.0400-0.12%09:05 EST

Volume:549.49K

Turnover:17.66M

Market Cap:1.85B

PE:47.38

High:32.95

Open:30.90

Low:30.79

Close:31.99

52wk High:38.69

52wk Low:5.35

Shares:57.12M

Float Shares:38.09M

Volume Ratio:0.83

T/O Rate:1.44%

Dividend:- -

Dividend Rate:- -

EPS(TTM):0.6847

EPS(LYR):-1.6475

ROE:15.02%

ROA:5.20%

PB:6.01

PE(LYR):-19.69

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Overview Company News Filings

BRIEF-Stoke Therapeutics Announces First Patient Dosed In Phase 1 Study Of Stk-002

Stoke Therapeutics Doses First Patient in Phase 1 Trial of STK-002 for Autosomal Dominant Optic Atrophy

Stoke Therapeutics Inc: Dose Escalation of First Four Cohorts Will Continue Through 2026 and Early 2027, Pending Safety and Tolerability Assessments

THOMSON REUTERS

Stoke Therapeutics Announces First Patient Dosed in Phase 1 Study of Stk-002, a Potential Disease-Modifying Medicine for the Treatment of Autosomal Dominant Optic Atrophy (Adoa)

THOMSON REUTERS

Stoke Therapeutics präsentiert auf dem Guggenheim Emerging Outlook: Biotech Summit

Will Stoke’s New Waltham Headquarters for Zorevunersen Commercialization Shift Stoke Therapeutics' (STOK) Narrative?

Simply Wall St.

Stoke Therapeutics Signs Lease for New 98,500-Square-Foot Headquarters in Waltham

How Accelerated EMPEROR Enrollment and Expedited FDA Talks At Stoke Therapeutics (STOK) Have Changed Its Investment Story

Simply Wall St.

Stoke Therapeutics (STOK) Valuation Check As Phase 3 Dravet Study Advances And FDA Discussions Progress

Simply Wall St.

Stoke Therapeutics Grants Stock Options to New Employees Under Inducement Plan

Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

THOMSON REUTERS

Stoke Therapeutics Down Over 16%, on Pace for Largest Percent Decrease Since February 2024 -- Data Talk

Stoke Therapeutics to Present at J.P. Morgan Healthcare Conference

Stoke Therapeutics updates timeline for Phase 3 EMPEROR study

Stoke Therapeutics Showcases Pipeline Advancements for Dravet Syndrome and Rare Genetic Diseases

BRIEF-Stoke Therapeutics Expects To Complete Enrollment Of 150 Patients In Q2 2026, With A Phase 3 Data Readout In Mid-2027 for Zorevunersen

Stoke Therapeutics Accelerates Phase 3 EMPEROR Study Enrollment for Dravet Syndrome Drug Zorevunersen

Stoke Therapeutics Announces Updates to Timelines for the Completion of Enrollment and a Phase 3 Data Readout From the Emperor Study of Zorevunersen for the Treatment of Dravet Syndrome

THOMSON REUTERS

Stoke Therapeutics Inc: Expects to Complete Enrollment of 150 Patients in Q2 2026, With a Phase 3 Data Readout in Mid-2027

THOMSON REUTERS

Stoke Therapeutics Inc - Continues to Explore Potential for Expedited Development, Registration and Delivery of Zorevunersen to Patients

THOMSON REUTERS

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Clinical results have not yet been presented.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260211:nNDL5Z3jFm:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2610932736","title":"Stoke Therapeutics Inc: Dose Escalation of First Four Cohorts Will Continue Through 2026 and Early 2027, Pending Safety and Tolerability Assessments","url":"https://stock-news.laohu8.com/highlight/detail?id=2610932736","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610932736?lang=en_us&edition=fundamental","pubTime":"2026-02-11 20:30","pubTimestamp":1770813001,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260211:nTUA6YHZLR:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2610932210","title":"Stoke Therapeutics Announces First Patient Dosed in Phase 1 Study of Stk-002, a Potential Disease-Modifying Medicine for the Treatment of Autosomal Dominant Optic Atrophy (Adoa)","url":"https://stock-news.laohu8.com/highlight/detail?id=2610932210","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2610932210?lang=en_us&edition=fundamental","pubTime":"2026-02-11 20:30","pubTimestamp":1770813001,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260211:nTUA6YHZLR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","STOK"],"gpt_icon":0},{"id":"2609318350","title":"Stoke Therapeutics präsentiert auf dem Guggenheim Emerging Outlook: Biotech Summit","url":"https://stock-news.laohu8.com/highlight/detail?id=2609318350","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2609318350?lang=en_us&edition=fundamental","pubTime":"2026-02-05 05:01","pubTimestamp":1770238886,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. wird am Mittwoch, den 11. Februar 2026, um 14:30 Uhr  auf dem Guggenheim Emerging Outlook: Biotech Summit 2026 prsentieren. CEO Ian F. Smith stellt das Unternehmen und aktuelle Entwicklungen im Bereich RNA-Medizin vor.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Stoke Therapeutics Inc. published the original content used to generate this news brief via Business Wire  on February 04, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260204:nNDL8dNm3S:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","STOK"],"gpt_icon":0},{"id":"2608837555","title":"Will Stoke’s New Waltham Headquarters for Zorevunersen Commercialization Shift Stoke Therapeutics' (STOK) Narrative?","url":"https://stock-news.laohu8.com/highlight/detail?id=2608837555","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2608837555?lang=en_us&edition=fundamental","pubTime":"2026-02-02 09:11","pubTimestamp":1769994694,"startTime":"0","endTime":"0","summary":"In January 2026, Stoke Therapeutics entered into a long-term lease for a new 98,500 square-foot headquarters and laboratory at 245 Fifth Avenue in Waltham, Massachusetts, with aggregate estimated base rent of about US$85.5 million through March 31, 2038. \nThis expanded facility, backed by a US$3 million security deposit, is intended to support Stoke’s preparations to commercialize its potential Dravet syndrome medicine, zorevunersen, and broaden research based on its proprietary...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/will-stokes-new-waltham-headquarters-for-zorevunersen-commer","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/will-stokes-new-waltham-headquarters-for-zorevunersen-commer","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","STOK"],"gpt_icon":0},{"id":"2606274732","title":"Stoke Therapeutics Signs Lease for New 98,500-Square-Foot Headquarters in Waltham","url":"https://stock-news.laohu8.com/highlight/detail?id=2606274732","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2606274732?lang=en_us&edition=fundamental","pubTime":"2026-01-28 03:06","pubTimestamp":1769540816,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. has announced plans to relocate its headquarters to a new 98,500 square-foot facility at 245 Fifth Avenue in Waltham, Massachusetts. The move, set for late 2026 when the company’s current Bedford lease ends, will support Stoke’s efforts to commercialize its lead medicine, zorevunersen, for Dravet syndrome and expand research activities.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Stoke Therapeutics Inc. published the original content used to generate this news brief via PR Newswire  on January 27, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260127:nNDLcbNBwW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2606258663","title":"How Accelerated EMPEROR Enrollment and Expedited FDA Talks At Stoke Therapeutics (STOK) Have Changed Its Investment Story","url":"https://stock-news.laohu8.com/highlight/detail?id=2606258663","media":"Simply Wall St.","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2606258663?lang=en_us&edition=fundamental","pubTime":"2026-01-25 07:17","pubTimestamp":1769296659,"startTime":"0","endTime":"0","summary":"Earlier in January 2026, Stoke Therapeutics announced accelerated timelines for completing enrollment in the Phase 3 EMPEROR study of zorevunersen in Dravet syndrome, with enrollment now expected to finish in the second quarter of 2026 and a Phase 3 data readout anticipated in mid-2027 to support a rolling NDA submission.\nAn important insight is the ongoing multidisciplinary dialogue with the FDA under Breakthrough Therapy Designation, which highlights active exploration of expedited...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/how-accelerated-emperor-enrollment-and-expedited-fda-talks-a","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/how-accelerated-emperor-enrollment-and-expedited-fda-talks-a","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2605149591","title":"Stoke Therapeutics (STOK) Valuation Check As Phase 3 Dravet Study Advances And FDA Discussions Progress","url":"https://stock-news.laohu8.com/highlight/detail?id=2605149591","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2605149591?lang=en_us&edition=fundamental","pubTime":"2026-01-22 18:33","pubTimestamp":1769077981,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics (STOK) recently outlined faster enrollment and a clearer data timeline for its Phase 3 EMPEROR study of zorevunersen in Dravet syndrome, along with ongoing FDA discussions on potential expedited review options.\nSee our latest analysis for Stoke Therapeutics.\nThe latest Dravet syndrome update comes after a mixed period for the shares, with a 1 day share price return of 2.72% contrasting with a 30 day share price return decline of 11.99%. The 1 year total shareholder return...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/stoke-therapeutics-stok-valuation-check-as-phase-3-dravet-st","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-stok/stoke-therapeutics/news/stoke-therapeutics-stok-valuation-check-as-phase-3-dravet-st","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["PRGS","LU2065732104.USD","DCF","BK4097","STOK","BK4139"],"gpt_icon":0},{"id":"2604919566","title":"Stoke Therapeutics Grants Stock Options to New Employees Under Inducement Plan","url":"https://stock-news.laohu8.com/highlight/detail?id=2604919566","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2604919566?lang=en_us&edition=fundamental","pubTime":"2026-01-17 05:01","pubTimestamp":1768597273,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. has granted stock options to purchase a total of 74,020 shares of common stock to nine new employees. The options have an exercise price of $29.28 per share, matching the closing price of the company's stock on January 15, 2026. Each option vests over four years, with one-quarter vesting on the first anniversary of the vesting commencement date and the remaining shares vesting monthly over the subsequent 36 months. The options have a ten-year term and are issued under the company's 2023 Inducement Plan.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Stoke Therapeutics Inc. published the original content used to generate this news brief via Business Wire  on January 16, 2026, and is solely responsible for the inf","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260116:nNDL6HYXr8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","STOK"],"gpt_icon":0},{"id":"2604191958","title":"Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)","url":"https://stock-news.laohu8.com/highlight/detail?id=2604191958","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2604191958?lang=en_us&edition=fundamental","pubTime":"2026-01-17 05:01","pubTimestamp":1768597260,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260116:nTUA3NQ0KH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","STOK"],"gpt_icon":0},{"id":"2603654724","title":"Stoke Therapeutics Down Over 16%, on Pace for Largest Percent Decrease Since February 2024 -- Data Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2603654724","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2603654724?lang=en_us&edition=fundamental","pubTime":"2026-01-13 01:39","pubTimestamp":1768239540,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics, Inc.  is currently at $27.44, down $5.41 or 16.47%. --Would be lowest close since Nov. 17, 2025, when it closed at $26.95. --On pace for largest percent decrease since Feb. 13, 2024, when it fell 17.27%. --Currently down four consecutive days; down 22.09% over this period. --Longest losing streak since Nov. 6, 2025, when it fell for five straight trading days. --Down 60.69% from its all-time closing high of $69.81 on Jan. 19, 2021. --Up 207.62% from 52 weeks ago , when it closed at $8.92. --Down 22.92% from its 52-week closing high of $35.60 on Oct. 15, 2025. --Up 365.08% from its 52-week closing low of $5.90 on April 8, 2025. --Traded as low as $25.21; lowest intraday level since Nov. 13, 2025, when it hit $24.34. --Down 23.26% at today's intraday low; largest intraday percent decrease since July 25, 2023, when it fell as much as 35.83%","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4539","BK4139","BK4007","LENZ"],"gpt_icon":0},{"id":"2603542882","title":"Stoke Therapeutics to Present at J.P. Morgan Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2603542882","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2603542882?lang=en_us&edition=fundamental","pubTime":"2026-01-13 00:25","pubTimestamp":1768235140,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. will present at the 44th Annual J.P. Morgan Healthcare Conference on Tuesday, January 13, 2026, at 4:30pm Pacific Time in San Francisco, CA. A live audio webcast of the presentation will be available on the Investors & News section of Stoke's website, with a replay accessible for 30 days following the event.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Stoke Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on January 12, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nNDL1ShlxR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2602550414","title":"Stoke Therapeutics updates timeline for Phase 3 EMPEROR study","url":"https://stock-news.laohu8.com/highlight/detail?id=2602550414","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602550414?lang=en_us&edition=fundamental","pubTime":"2026-01-12 03:55","pubTimestamp":1768161307,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics (STOK) announced accelerated timelines for the completion of enrollment and a Phase 3 data readout from the EMPEROR study. Compl...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/stoke-therapeutics-updates-timeline-for-phase-3-emperor-study-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/stoke-therapeutics-updates-timeline-for-phase-3-emperor-study-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","BK4539","STOK","BK4139","LENZ"],"gpt_icon":0},{"id":"2602557755","title":"Stoke Therapeutics Showcases Pipeline Advancements for Dravet Syndrome and Rare Genetic Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2602557755","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602557755?lang=en_us&edition=fundamental","pubTime":"2026-01-12 03:04","pubTimestamp":1768158255,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. presented updates on its pipeline of RNA-based medicines targeting diseases caused by protein insufficiency. The company highlighted progress in its lead program, zorevunersen, for Dravet syndrome, noting that Phase 3 enrollment is underway with completion expected in the second quarter of 2026 and a data readout anticipated in mid-2027 to support a potential NDA filing. Additional updates included the initiation of a Phase 1 study of STK-002 for Autosomal Dominant Optic Atrophy  in the UK and Europe, and ongoing lead optimization to identify a clinical candidate for SYNGAP1-related disorders in 2026. Stoke reported a strong balance sheet with approximately $391.7 million in cash, cash equivalents, and marketable securities as of December 31, 2025, and outlined continued investment in research and platform expansion. You can access the full presentation through the link below.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260111:nNDL8HfSmx:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2602557734","title":"BRIEF-Stoke Therapeutics Expects To Complete Enrollment Of 150 Patients In Q2 2026, With A Phase 3 Data Readout In Mid-2027 for Zorevunersen","url":"https://stock-news.laohu8.com/highlight/detail?id=2602557734","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602557734?lang=en_us&edition=fundamental","pubTime":"2026-01-12 03:03","pubTimestamp":1768158189,"startTime":"0","endTime":"0","summary":"BRIEF-Stoke Therapeutics Expects To Complete Enrollment Of 150 Patients In Q2 2026, With A Phase 3 Data Readout In Mid-2027 for ZorevunersenJan 11 (Reuters) - Stoke Therapeutics Inc STOK.O:STOKE THERA","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260111:nTUA8ZB7PR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["STOK","BK4139"],"gpt_icon":0},{"id":"2602557201","title":"Stoke Therapeutics Accelerates Phase 3 EMPEROR Study Enrollment for Dravet Syndrome Drug Zorevunersen","url":"https://stock-news.laohu8.com/highlight/detail?id=2602557201","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2602557201?lang=en_us&edition=fundamental","pubTime":"2026-01-12 03:00","pubTimestamp":1768158021,"startTime":"0","endTime":"0","summary":"Stoke Therapeutics Inc. announced updates to the clinical development timeline for its lead investigational medicine, zorevunersen, which is being developed in collaboration with Biogen as a potential disease-modifying treatment for Dravet syndrome. The company now expects to complete enrollment of 150 patients in the Phase 3 EMPEROR study by the second quarter of 2026. A data readout from this study is anticipated in mid-2027 and is expected to support a New Drug Application  submission to the U.S. Food and Drug Administration . Stoke Therapeutics plans to initiate a rolling NDA submission in the first half of 2027. Results from the Phase 3 EMPEROR study have not yet been presented. The company also noted ongoing discussions with the FDA regarding the expedited development and potential registration of zorevunersen.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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