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Merck

85.20

+0.49000.58%

Pre-market: 85.05-0.1500-0.18%08:18 EDT

Volume:13.83M

Turnover:1.17B

Market Cap:214.40B

PE:12.39

High:85.83

Open:85.27

Low:83.79

Close:84.71

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Overview Company News Filings

Germany's Merck KGaA in $3.9 billion deal to buy US biotech firm SpringWorks

Merck KGaA, Darmstadt, Germany to Acquire SpringWorks Therapeutics to Accelerate Sustainable Growth of Healthcare Business

Wall Street's New Tariff Safe Haven: High-Tax Biotech Stocks

Merck & Co., Inc. (MRK): Among Billionaire Ken Fisher’s Healthcare Stock Picks with Massive Upside Potential

KEYTRUDA® (pembrolizumab) as Perioperative Treatment With Standard of Care (SOC) Adjuvant Therapy Significantly Improved Event-Free Survival Compared to SOC Alone in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

2 Outstanding Dividend Stocks to Buy and Hold For 20 Years

Akeso survival data for ivonescimab misses expectations, STAT says

Merck First Quarter 2025 Earnings: Beats Expectations

Simply Wall St.

Merck’s Earnings Call: Growth Potential and Challenges

BUZZ-Summit Therapeutics closes 36% lower after interim data for cancer drug

BMO Capital Adjusts Price Target on Merck to $82 From $89

MT Newswires Live

Goldman Sachs Adjusts Merck Price Target to $99 From $103, Maintains Buy Rating

MT Newswires Live

ALX Oncology's Phase 2 Trials of Evorpacept, Keytruda Combination in Head, Neck Cancers Fail to Meet Primary Endpoints

MT Newswires Live

Dow's 117-Point Drop Led By Losses In Merck, Verizon Shares

ALX Oncology Reports ASPEN-03 and ASPEN-04 Phase 2 Trials Evaluating Evorpacept with a Checkpoint Inhibitor for the Treatment of Head and Neck Cancers Did Not Meet Primary Endpoints

SpringWorks in Late-Stage Buyout Talks With Merck

MT Newswires Live

Citi Remains a Buy on Merck & Company (MRK)

AbbVie lifts profit forecast, downplays tariff threat

Morgan Stanley Cuts Price Target on Merck to $99 From $106, Keeps Equalweight Rating

MT Newswires Live

AbbVie lifts profit forecast on strong sales of newer immunology drugs

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Merck KGaA in $3.9 billion deal to buy US biotech firm SpringWorks","url":"https://stock-news.laohu8.com/highlight/detail?id=2530443721","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530443721?lang=en_us&edition=fundamental","pubTime":"2025-04-28 14:37","pubTimestamp":1745822270,"startTime":"0","endTime":"0","summary":"UPDATE 2-Germany's Merck KGaA in $3.9 billion deal to buy US biotech firm SpringWorksMerck shares fall in early tradeUncertainty caused by Trump policies overshadows possible dealsTransaction could close in second half, Merck saysRecasts, adds details, background from paragraph 7By Ludwig 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plexiform neurofibromas –。– Planned acquisition will strengthen the presence of Merck KGaA, Darmstadt, Germany’s Healthcare business in the United States and expand reach of SpringWorks' therapeutic innovations to more patients with rare tumors worldwide –。Upon closing, the business combination will immediately contribute to Merck KGaA, Darmstadt, Germany’s 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Street's New Tariff Safe Haven: High-Tax Biotech Stocks","url":"https://stock-news.laohu8.com/highlight/detail?id=2530311314","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530311314?lang=en_us&edition=fundamental","pubTime":"2025-04-28 11:21","pubTimestamp":1745810498,"startTime":"0","endTime":"0","summary":"Chief Executives don't usually brag about paying high tax rates.But with pharma tariffs looming, being a tax sucker is suddenly a badge of safety in the industry. That isn't because Wall Street is suddenly in love with taxes. Rather, with so much uncertainty, investors are prizing biotech companies that base their intellectual property and manufacturing in the U.S., which up until now often meant higher taxes.On a Thursday earnings call, Gilead Sciences Chief Executive Daniel O'Day proudly pointed out that the biotech's corporate tax rate of approximately 20% \"reflects the fact that the substantial majority of our intellectual property is already registered in the United States.\". \"There is a startlingly short list of biotech and therapeutic stocks that have largely U.S. sales, I.P.  domiciled in the U.S.,\" and limited impact from tariffs and drug pricing policies, J","market":"sg","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2456880835.USD","LU0965509283.SGD","SG9999015341.SGD","LU0320765646.SGD","IE00BLSP4452.SGD","LU2236285917.USD","LU1035775433.USD","LU1989772923.USD","MRK","LU0823416689.USD","BK4566","LU1559883803.SGD","LU2237438978.USD","LU1035773651.USD","LU2023250504.SGD","IE00BZ1G4Q59.USD","LU1929549753.HKD","IE0002270589.USD","LU1917777945.USD","BK4007","LU1941712348.USD","IE00B19Z3B42.SGD","LU1057294990.SGD","BK4559","LU0238689110.USD","BK4588","IE00B7SZLL34.SGD","GILD","VERX","LU2417539215.USD","VRTX","LU1983299246.USD","LU2468319806.SGD","IE00BLSP4239.USD","LU0234570918.USD","IE00B19Z9Z06.USD","LU0889565916.HKD","LU0211331839.USD","LU1699723380.USD","LU2087621335.USD","LU1934455863.HKD","SGXZ57979304.SGD","LU0965508806.USD","LU0006306889.USD","LU1069344957.HKD","LU2023250843.SGD","LU2106854487.HKD","BK4567","BK4550","LU1023059063.AUD"],"gpt_icon":1},{"id":"2530468804","title":"Merck & Co., Inc. (MRK): Among Billionaire Ken Fisher’s Healthcare Stock Picks with Massive Upside Potential","url":"https://stock-news.laohu8.com/highlight/detail?id=2530468804","media":"Insider Monkey","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530468804?lang=en_us&edition=fundamental","pubTime":"2025-04-28 03:08","pubTimestamp":1745780883,"startTime":"0","endTime":"0","summary":"We recently published a list of Billionaire Ken Fisher’s 10 Healthcare Stock Picks with Massive Upside Potential. In this article, we are going to take a look at where Merck & Co., Inc.  stands against other Billionaire Ken Fisher’s healthcare stock picks with massive upside potential.The healthcare industry, an essential component of global well-being and economic resilience, is undergoing significant changes. The industry, which is thought to account for more than 10% of the world’s GDP, is set to enter a new era characterized by demographic shifts, digital innovation, and regulatory realignment. Stakeholders in the life sciences, diagnostics, and healthcare services ecosystem face a conundrum as of 2025: stability is threatened by ongoing financial strain, growing operational complexity, and geopolitical risks, despite the abundance of growth opportunities.Meanwhile, recent geopolitical developments are casting a shadow on global healthcare supply networks. In April 2025, President ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/merck-co-inc-mrk-among-190803126.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0106261372.USD","LU0965509101.SGD","LU2468319806.SGD","LU0208291251.USD","LU1057294990.SGD","SG9999013999.USD","LU0211331839.USD","IE000M9KFDE8.USD","LU0122379950.USD","SG9999001176.USD","BK4550","LU1037948897.HKD","LU2089984988.USD","IE00B2B36J28.USD","LU1066051498.USD","LU0965509283.SGD","LU0238689110.USD","IE0002141913.USD","LU0265550946.USD","LU1291159041.SGD","LU0058720904.USD","LU0965508806.USD","LU0861579265.USD","IE00BLSP4452.SGD","LU1023059063.AUD","LU1974910355.USD","LU1430594728.SGD","MRK","SG9999014559.SGD","BK4588","LU2112291526.USD","BK4137","IE00BBT3K403.USD","HCSG","IE00B1BXHZ80.USD","LU1699723380.USD","LU1585245621.USD","LU0203345920.USD","LU2461242641.AUD","LU2106854487.HKD","LU1066051225.USD","LU1066051811.HKD","SGXZ57979304.SGD","LU0006306889.USD","BK4007","LU1989772923.USD","SG9999014542.SGD","LU0289739699.SGD","LU0985320562.USD","LU0070302665.USD"],"gpt_icon":0},{"id":"2530548354","title":"KEYTRUDA® (pembrolizumab) as Perioperative Treatment With Standard of Care (SOC) Adjuvant Therapy Significantly Improved Event-Free Survival Compared to SOC Alone in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2530548354","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530548354?lang=en_us&edition=fundamental","pubTime":"2025-04-28 00:00","pubTimestamp":1745769600,"startTime":"0","endTime":"0","summary":"KEYNOTE-689 marks the first positive trial in more than two decades for patients with resected locally advanced head and neck squamous cell carcinoma . Results to be presented at American Association for Cancer Research  Annual Meeting 2025 during a Plenary Session and included in official meeting press program. \"As the first positive trial in over two decades for patients with resectable, locally advanced head and neck squamous cell carcinoma, the presentation of these landmark results marks an important moment for these patients and those who care for them,\" said Dr. Ravindra Uppaluri, the study’s co-principal investigator, director of Head and Neck Surgical Oncology, Brigham and Women’s Hospital and Dana-Farber","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/keytruda-pembrolizumab-perioperative-treatment-standard-160000135.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CRT","BK4135","LU1854103824.USD","BK4161","LU0289739699.SGD","SG9999015358.SGD","CPS","HSCT","BK4533","LU2023250843.SGD","BK4097","LU0054578231.USD","LU0861579265.USD","HCC","IE00BZ199S13.USD","LU0208291251.USD","ALT","LU1861220033.SGD","LU1934455194.USD","LU2361044949.HKD","IE0009355771.USD","ON","OS","IE00B7SZL793.SGD","LU2106854487.HKD","SOC","LU2298322129.HKD","IE00BLSP4452.SGD","LU0320765489.SGD","CRC","LU1430594728.SGD","LU1066051225.USD","LU1037948541.HKD","ITT","LU0265550946.USD","SMP","BCG","MRK","BTC","RCC","IE00BLSP4239.USD","LU0320765646.SGD","AEIS","LU2361044865.SGD","SGXZ57979304.SGD","SG9999014567.USD","BK4605","DM","SG9999001440.SGD","LU1162221912.USD"],"gpt_icon":0},{"id":"2530628175","title":"2 Outstanding Dividend Stocks to Buy and Hold For 20 Years","url":"https://stock-news.laohu8.com/highlight/detail?id=2530628175","media":"Motley Fool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530628175?lang=en_us&edition=fundamental","pubTime":"2025-04-27 02:32","pubTimestamp":1745692320,"startTime":"0","endTime":"0","summary":"Medtronic can navigate the impact of Trump's tariffs and still perform well in the long run.Merck will face challenges to its biggest franchise, but it can get around this issue.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/investing/2025/04/26/2-outstanding-dividend-stocks-to-buy-and-hold-for/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":["LU1934455863.HKD","LU1983299246.USD","LU0058720904.USD","LU0122379950.USD","LU2112291526.USD","SG9999014567.USD","LU1093756168.USD","LU2106854487.HKD","LU1066053197.SGD","LU0203347892.USD","LU0265550359.USD","LU0320765489.SGD","IE00B1BXHZ80.USD","LU1066051498.USD","LU1989772923.USD","LU2023250843.SGD","SG9999002224.SGD","SG9999013999.USD","LU0208291251.USD","LU0985320562.USD","LU0965509010.AUD","LU2361044949.HKD","IE00BFTCPJ56.SGD","LU1057294990.SGD","MRK","IE0002141913.USD","LU1162221912.USD","LU2461242641.AUD","LU1116320737.USD","LU1116320901.HKD","LU0861579265.USD","LU1061106388.HKD","IE00BBT3K403.USD","LU1585245621.USD","LU1066051225.USD","LU1941712264.USD","IE00BJJMRZ35.SGD","LU0106261372.USD","SG9999015358.SGD","LU0320765646.SGD","LU2361045086.USD","SG9999014575.USD","LU2361044865.SGD","LU0070302665.USD","LU1941712348.USD","IE00B4R5TH58.HKD","BK4533","LU0965509283.SGD","IE000M9KFDE8.USD","SG9999014542.SGD"],"gpt_icon":0},{"id":"2530120765","title":"Akeso survival data for ivonescimab misses expectations, STAT says","url":"https://stock-news.laohu8.com/highlight/detail?id=2530120765","media":"TipRanks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530120765?lang=en_us&edition=fundamental","pubTime":"2025-04-27 00:50","pubTimestamp":1745686217,"startTime":"0","endTime":"0","summary":"While Akeso  and Summit Therapeutics’  ivonescimab, a rival to Merck’s  Keytruda, won approval in China this week, the data on patient survival did not meet analyst expectations, Jonathan Wosen of STAT reports. In its submission to regulators, Akeso included data on patient survival, disclosing that an interim analysis following 157 patient deaths found that participants on ivonescimab had a roughly 22% reduced risk of death, with a hazard ratio of 0.784, a company spokesperson confirmed to STAT. That finding is not statistically significant, but it does meet market analyst expectations, according to Wosen. In an email to STAT, an Akeso spokesperson noted that the interim analysis was not powered for statistical significance and that the company plans to conduct formal analyses of survival once 232 and 280 deaths have occurred in the trial. Shares of Summit Therapeutics fell 37% to $23.21 following the report before halting for news. BioNTech  dropped 17% to $100.06 in sympathy with Su","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/akeso-survival-data-ivonescimab-misses-165017764.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/akeso-survival-data-ivonescimab-misses-165017764.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0122379950.USD","IE00BBT3K403.USD","LU0265550946.USD","LU1162221912.USD","BK4585","LU0965509101.SGD","LU2361044949.HKD","LU1585245621.USD","LU0265550359.USD","LU1116320737.USD","LU1066051225.USD","BK4548","LU1035773651.USD","BK4588","LU1934455194.USD","LU2468319806.SGD","AKESF","SG9999014575.USD","IE000M9KFDE8.USD","BK4535","LU0238689110.USD","LU0965509283.SGD","LU0965509010.AUD","LU1989772923.USD","IE00BFTCPJ56.SGD","BK4568","LU0058720904.USD","LU1929549753.HKD","LU2023250843.SGD","MRK","LU2106854487.HKD","BK4007","LU1934455277.USD","SMMT","IE00BJJMRZ35.SGD","SG9999002224.SGD","LU1291159041.SGD","IE00BSNM7G36.USD","IE0009355771.USD","IE00B1BXHZ80.USD","SG9999001176.USD","LU2361044865.SGD","LU1941712264.USD","SG9999015358.SGD","LU0203345920.USD","LU2488822045.USD","IE00BJT1NW94.SGD","LU1066051498.USD","BNTX","LU1934455863.HKD"],"gpt_icon":1},{"id":"2530285129","title":"Merck First Quarter 2025 Earnings: Beats Expectations","url":"https://stock-news.laohu8.com/highlight/detail?id=2530285129","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530285129?lang=en_us&edition=fundamental","pubTime":"2025-04-26 21:00","pubTimestamp":1745672449,"startTime":"0","endTime":"0","summary":"Profit margin: 33% . The increase in margin was driven by lower expenses.Trump has pledged to \"unleash\" American oil and gas and these 15 US stocks have developments that are poised to benefit.NYSE:MRK Earnings and Revenue Growth April 26th 2025. All figures shown in the chart above are for the trailing 12 month  period. Revenue exceeded analyst estimates by 1.3%. Earnings per share  also surpassed analyst estimates by 4.0%.Looking ahead, revenue is forecast to grow 3.2% p.a. on average during the next 3 years, compared to a 8.8% growth forecast for the Pharmaceuticals industry in the US.The company's shares are up 6.1% from a week ago.You should learn about the   1 warning sign  we've spotted with Merck.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/merck-first-quarter-2025-earnings-130049639.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["MRK"],"gpt_icon":0},{"id":"2530190175","title":"Merck’s Earnings Call: Growth Potential and Challenges","url":"https://stock-news.laohu8.com/highlight/detail?id=2530190175","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530190175?lang=en_us&edition=fundamental","pubTime":"2025-04-26 08:23","pubTimestamp":1745626987,"startTime":"0","endTime":"0","summary":"Merck & Company (($MRK)) has held its Q1 earnings call. Read on for the main highlights of the call. Merck & Co. Earnings Call Highlights Growth Po...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/mercks-earnings-call-growth-potential-and-challenges?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/mercks-earnings-call-growth-potential-and-challenges?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["MRK"],"gpt_icon":0},{"id":"2530919698","title":"BUZZ-Summit Therapeutics closes 36% lower after interim data for cancer drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2530919698","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530919698?lang=en_us&edition=fundamental","pubTime":"2025-04-26 06:01","pubTimestamp":1745618508,"startTime":"0","endTime":"0","summary":"BUZZ-Summit Therapeutics closes 36% lower after interim data for cancer drug** Shares of Summit Therapeutics SMMT.O settle 36% lower to $23.47 at close, last up 3.81% to $24.36 in after-market trade** Co says in the submission for cancer drug ivonescimab in China by partner Akeso 9926.HK, the regulators asked for an interim analysis of overall survival** The drug was approved in China based on a trial that studied it against Merck's MRK.N Keytruda in patients with a type of lung cancer** The analysis showed a potential 22% reduced risk of death, with a hazard ratio of 0.777, which is not statistically significant, two analysts said** The simple fact that this still early cut is not statistically significant is triggering a massive sell-off - Evercore ISI** Summit said the interim analysis was conducted at 39% data maturity** Brokerage Truist expects overall survival benefit will reach statistical significance by the final analysis, if not potentially earlier** SMMT shares peaked in Sep","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250425:nL4N3R322S:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","SG9999014542.SGD","LU1699723380.USD","BK4007","LU2089984988.USD","LU0234572021.USD","IE00BSNM7G36.USD","LU2361045086.USD","LU0211331839.USD","LU0320765489.SGD","BK4559","LU1989772923.USD","SGXZ57979304.SGD","LU0238689110.USD","BK4516","LU1929549753.HKD","LU0265550359.USD","MRK","IE00B543WZ88.USD","LU0203345920.USD","LU1066051811.HKD","LU1093756168.USD","SG9999002224.SGD","LU1066051498.USD","LU1116320901.HKD","IE0002141913.USD","LU1974910355.USD","LU2112291526.USD","EVR","LU1037948541.HKD","IE00B1BXHZ80.USD","LU0058720904.USD","LU1720050803.USD","LU1934455277.USD","LU2324357040.USD","LU2468319806.SGD","SG9999001176.SGD","LU0203347892.USD","LU2461242641.AUD","LU0348783233.USD","LU1989772840.SGD","LU1035773651.USD","BK1161","IE00BJT1NW94.SGD","LU0122379950.USD","LU2106854487.HKD","SMMT","LU0861579265.USD","BK4127"],"gpt_icon":1},{"id":"2530159049","title":"BMO Capital Adjusts Price Target on Merck to $82 From $89","url":"https://stock-news.laohu8.com/highlight/detail?id=2530159049","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530159049?lang=en_us&edition=fundamental","pubTime":"2025-04-25 23:47","pubTimestamp":1745596051,"startTime":"0","endTime":"0","summary":"Merck (MRK) has an average rating of overweight and mean price target of $109.63, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BMO","MRK"],"gpt_icon":0},{"id":"2530124132","title":"Goldman Sachs Adjusts Merck Price Target to $99 From $103, Maintains Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2530124132","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530124132?lang=en_us&edition=fundamental","pubTime":"2025-04-25 21:53","pubTimestamp":1745589228,"startTime":"0","endTime":"0","summary":"Merck & Co (MRK) has an average rating of overweight and mean price target of $109.63, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major b","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["MRK"],"gpt_icon":0},{"id":"2530131735","title":"ALX Oncology's Phase 2 Trials of Evorpacept, Keytruda Combination in Head, Neck Cancers Fail to Meet Primary Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2530131735","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530131735?lang=en_us&edition=fundamental","pubTime":"2025-04-25 21:52","pubTimestamp":1745589120,"startTime":"0","endTime":"0","summary":"ALX Oncology  said Friday that two phase 2 trials evaluating evorpacept in combination with Merck's  Keytruda in patients with advanced head and neck squamous cell carcinoma failed to meet their primary endpoints of improved objective response rates.The company said efficacy data from the trials do not support advancing the combination into a registrational study and it will no longer pursue the combination therapy in advanced head and neck squamous cell carcinoma.ALX said, however, that several trials of evorpacept in combination with other anti-cancer antibodies will continue based on established proof-of-concept.ALX Oncology shares were down more than 4% in recent Friday trading.Price: 0.58, Change: -0.02, Percent Change: -3.49","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0266013472.USD","LU1291159041.SGD","LU0070302665.USD","BK4516","SG9999015341.SGD","LU1989771016.USD","LU0965508806.USD","LU0058720904.USD","BK4139","LU1023059063.AUD","LU1093756325.SGD","LU1061106388.HKD","IE00B1BXHZ80.USD","LU0965509101.SGD","LU0289739699.SGD","LU1941712348.USD","MRK","LU1069347547.HKD","IE00BJJMRZ35.SGD","LU1093756168.USD","ALX","LU2468319806.SGD","LU1941712264.USD","LU1116320737.USD","LU2023250504.SGD","SG9999014559.SGD","LU2023250843.SGD","BK4585","LU2324357040.USD","LU1037948541.HKD","LU0006306889.USD","SGXZ57979304.SGD","IE0009355771.USD","SG9999001176.SGD","LU2089984988.USD","LU1430594728.SGD","IE00BLSP4239.USD","LU1066053197.SGD","IE0002141913.USD","LU2112291526.USD","ALXO","LU0965509010.AUD","LU0985320562.USD","LU1585245621.USD","LU0965509283.SGD","LU1066051225.USD","BK4231","BK4533","LU0203347892.USD","IE00BSNM7G36.USD"],"gpt_icon":0},{"id":"2530319741","title":"Dow's 117-Point Drop Led By Losses In Merck, Verizon Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2530319741","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530319741?lang=en_us&edition=fundamental","pubTime":"2025-04-25 21:46","pubTimestamp":1745588760,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Merck and Verizon are retreating Friday morning, sending the Dow Jones Industrial Average into negative territory.Shares of Merck  and Verizon  have contributed to the index's intraday decline, as the Dow  was most recently trading 117 points, or 0.3%, lower.Merck's shares have fallen $1.65, or 2.1%, while those of Verizon are off $0.85 , combining for an approximately 15-point drag on the Dow.Other components contributing significantly to the decline include Nike , UnitedHealth , and Johnson & Johnson .A $1 move in any of the Dow's 30 components equates to a 6.15-point swing.Data source: Dow Jones Market Data, FactSet. Data compiled April 25, 2025.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":[".DJI","LU0316494557.USD","SG9999015341.SGD","SG9999018865.SGD","LU2361044865.SGD","IE00B894F039.SGD","DOG","LU1974910355.USD","LU1035773651.USD","LU0321505439.SGD","SDOW","LU2362541513.USD","UDOW","LU0225284248.USD","DXD","SGXZ51526630.SGD","LU0198837287.USD","LU1244550221.USD","LU1674673428.USD","JNJ","LU0528227936.USD","LU1093756325.SGD","LU2505996509.AUD","LU1917777945.USD","SG9999002232.USD","LU0868494617.USD","BK4516","IE00BVYPNW00.USD","DJX","IE00BJT1NW94.SGD","LU0310799852.SGD","VZ","LU1032466523.USD","LU1084165304.USD","IE00B19Z8W00.USD","LU1732800096.USD","LU0238689110.USD","SG9999001176.USD","MRK","LU1323610961.USD","LU1720051017.SGD","DDM","LU2211815571.USD","LU0251132253.USD","LU1059921491.USD","LU2361044949.HKD","LU0149725797.USD","BK4559"],"gpt_icon":1},{"id":"2530513653","title":"ALX Oncology Reports ASPEN-03 and ASPEN-04 Phase 2 Trials Evaluating Evorpacept with a Checkpoint Inhibitor for the Treatment of Head and Neck Cancers Did Not Meet Primary Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2530513653","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2530513653?lang=en_us&edition=fundamental","pubTime":"2025-04-25 21:00","pubTimestamp":1745586000,"startTime":"0","endTime":"0","summary":"In ASPEN-03 and ASPEN-04 trials, efficacy data do not support advancing evorpacept in combination with Merck’s anti-PD-1 therapy, KEYTRUDA , into a registrational study. Company remains confident in continuing to pursue evorpacept in multiple clinical trials, based on the different mechanism of evorpacept in combination with anti-cancer antibodies, as evidenced by durable clinical response and consistent safety data in prior clinical trials. In the ASPEN-03 and ASPEN-04 clinical trials, evorpacept was combined with pembrolizumab with or without chemotherapy to investigate a second and distinct mechanism of action. This discrete approach explored the concept that evorpacept may enhance T-cell priming by activating dendritic cells and stimulating the adaptive immune system. The trial outcomes were not sufficiently supportive of advancing evorpacept in combination with 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