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Sangamo Therapeutics, Inc.

0.1743

+0.018311.74%

Volume:3.25M

Turnover:553.03K

Market Cap:72.21M

PE:-0.46

High:0.1790

Open:0.1580

Low:0.1501

Close:0.1560

52wk High:0.7660

52wk Low:0.1000

Shares:414.27M

Float Shares:406.77M

Volume Ratio:- -

T/O Rate:0.80%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.3824

EPS(LYR):-0.4400

ROE:-2891.84%

ROA:-94.37%

PB:-3.81

PE(LYR):-0.40

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Overview Company News Filings

Concept

Gene Editing+1.92%

Capital Flow

Inflow:

Outflow:

News

Sangamo publishes corporate presentation on neurology genomic medicine platform, Fabry gene therapy

Sangamo Therapeutics posts ST-503 nonclinical safety presentation for small fiber neuropathy

Sangamo Therapeutics publishes ST-506 nonhuman primate brain presentation

Sangamo publishes TRAC locus modular integrase retargeting presentation

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publishes corporate presentation on neurology genomic medicine platform, Fabry gene therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2635254797","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635254797?lang=en_us&edition=fundamental","pubTime":"2026-05-15 04:25","pubTimestamp":1778790344,"startTime":"0","endTime":"0","summary":"Sangamo outlined a neurology-focused strategy built around zinc-finger epigenetic regulators paired with its STAC-BBB blood-brain barrier-penetrant AAV capsid platform.Fabry gene therapy ST-920 remains on rolling BLA submission, with nonclinical and clinical modules submitted; completion targeted as early as summer 2026, subject to securing additional funding.Cash and cash equivalents totaled USD 27.6 million as of March 31, 2026; funding runway guided into Q3 2026 under current operating plan, including potential additional cost reductions.Chronic pain program ST-503 is in Phase 1/2 STAND study with six active sites; prion disease program ST-506 remains in CTA-enabling work with GLP toxicology completed and analysis ongoing.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as fi","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260514:nNDL2m9Nh:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4556","SGMO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634974572","title":"Sangamo Therapeutics posts ST-503 nonclinical safety presentation for small fiber neuropathy","url":"https://stock-news.laohu8.com/highlight/detail?id=2634974572","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634974572?lang=en_us&edition=fundamental","pubTime":"2026-05-12 18:18","pubTimestamp":1778581117,"startTime":"0","endTime":"0","summary":"Sangamo published nonclinical safety results for ST-503, an investigational AAV9 gene therapy designed to repress SCN9A  for treatment of small fiber neuropathy.Six-month GLP study in cynomolgus monkeys reported no dose-limiting toxicity following one-time intrathecal dosing at 10,000,000,000,000, 60,000,000,000,000, 90,000,000,000,000 vg/animal.Pharmacology readouts at 6 months showed intended SCN9A repression in dorsal root ganglia, with activity also reported in trigeminal ganglia.Mouse fertility and embryo-fetal development study using a surrogate AAV9 ZFR at 5,710,000,000,000 vg/kg found no test-article-related adverse effects.Integration and germline assessments reported no evidence of AAV germline transmission to offspring, with liver integration profile described as low-level and polyclonal, supporting a low tumor-risk signal.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timel","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nNDLbbCGnp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SGMO","BK4139","BK4556"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634429743","title":"Sangamo Therapeutics publishes ST-506 nonhuman primate brain presentation","url":"https://stock-news.laohu8.com/highlight/detail?id=2634429743","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634429743?lang=en_us&edition=fundamental","pubTime":"2026-05-12 18:18","pubTimestamp":1778581084,"startTime":"0","endTime":"0","summary":"Sangamo Therapeutics published a research presentation on ST-506, a blood-brain barrier-penetrant AAV gene therapy designed to repress prion protein expression by targeting PRNP in neurons.Nonhuman primate brain data at 28 days post-dose showed 33.9% of superior frontal gyrus neurons classified as ZFR+ versus 0.29% for vehicle.Single-cell analysis showed PRNP expression reduced by more than 95% in ST-506-expressing neurons, with median PRNP spot total intensity down 21.1% in ZFR+ neurons versus vehicle.Program update cited tolerability in nonhuman primates at 1E+14 vg/kg over 28 days, supporting further clinical development in symptomatic prion disease.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sangamo Therapeutics Inc. published ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nNDLb5nTGG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SGMO","BK4139","BK4556"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634974362","title":"Sangamo publishes TRAC locus modular integrase retargeting presentation","url":"https://stock-news.laohu8.com/highlight/detail?id=2634974362","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634974362?lang=en_us&edition=fundamental","pubTime":"2026-05-12 18:17","pubTimestamp":1778581073,"startTime":"0","endTime":"0","summary":"Sangamo published a medical research presentation outlining a platform to retarget large serine integrases for targeted gene integration at therapeutically relevant genomic sites.Work described retargeting Bxb1 integrase to TRAC locus, reaching about 29% targeted integration with up to 44% GFP expression in primary human T cells.Zinc finger fusions lifted on-target performance while maintaining a stronger specificity profile than activity-boosting mutations, which reduced specificity in genome-wide off-target assays.Synthetic donor engineering designed to remove need for wild-type Bxb1, with donor changes reported to eliminate top nominated off-target integration sites in K562 cells for most active TRAC reagents.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, inve","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nNDL4PdtwM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SGMO","BK4556"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":4,"totalPage":13,"pageCount":1,"totalSize":51,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/SGMO\",params:#limit:6,delay:false,,,undefined,":[{"market":"US","name":"Gene Editing","id":"package_us_concept_jybj","bkCode":"BK4556","changeRate":0.0192}]}}