US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Nasdaq

90.22

+0.20000.22%

Post-market: 90.220.00000.00%19:29 EST

Volume:3.47M

Turnover:312.82M

Market Cap:51.52B

PE:32.22

High:90.54

Open:90.02

Low:89.87

Close:90.02

52wk High:97.63

52wk Low:64.84

Shares:571.00M

Float Shares:511.57M

Volume Ratio:1.14

T/O Rate:0.68%

Dividend:1.04

Dividend Rate:1.16%

EPS(TTM):2.80

EPS(LYR):1.94

ROE:14.05%

ROA:4.87%

PB:4.28

PE(LYR):46.48

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Overview Company News Filings

Concept

ETF & Stock Investment+0.21%

Fractional Shares+0.22%

Capital Flow

Inflow:

Outflow:

News

TScan Therapeutics Reports Positive Phase 1 Results for TSC-101 in Heme Malignancies

Fulcrum Therapeutics Reports Positive Phase 1b Results for Pociredir in Sickle Cell Disease

BioNTech Reports Gotistobart Shows Significant Survival Benefit in Phase 3 Lung Cancer Trial

Legend Biotech Reports CARVYKTI Achieves 50.4-Month Median PFS in Multiple Myeloma Trial

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Therapeutics Reports Positive Phase 1 Results for TSC-101 in Heme Malignancies","url":"https://stock-news.laohu8.com/highlight/detail?id=2589882206","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589882206?lang=en_us&edition=fundamental","pubTime":"2025-12-07 06:30","pubTimestamp":1765060219,"startTime":"0","endTime":"0","summary":"TScan Therapeutics Inc. has announced updated results from the ongoing ALLOHA Phase 1 trial  of TSC-101 in patients with hematologic malignancies undergoing allogeneic hematopoietic cell transplantation. The data were presented in a poster session at the 67th American Society of Hematology  Annual Meeting and Exposition. The trial results indicate that all three TSC-101-treated patients who reached two-year follow-up remained relapse-free, compared to one of four patients in the control arm. TSC-101 was well-tolerated, with no dose-limiting toxicities observed. The company plans to initiate a pivotal study of TSC-101 in the second quarter of 2026, following agreement from the U.S. Food and Drug Administration on the study design. A virtual Key Opinion Leader event discussing these results was scheduled for December 8.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, th","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251206:nNDL3Hs97p:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B64PRP62.GBP","IE00BGHQF748.EUR","IE00BKPKM429.USD","SG9999014013.SGD","BK4539","BK4112","LU0314104364.USD","NDAQ","BK4139","LU2210149790.SGD","SG9999014005.SGD","BK4585","SG9999014021.USD","TCRX","IE00B3QW5Z07.USD","LU2210150020.SGD","LU2095319765.USD","BK4588"],"gpt_icon":0},{"id":"2589822050","title":"Fulcrum Therapeutics Reports Positive Phase 1b Results for Pociredir in Sickle Cell Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2589822050","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589822050?lang=en_us&edition=fundamental","pubTime":"2025-12-07 06:30","pubTimestamp":1765060216,"startTime":"0","endTime":"0","summary":"Fulcrum Therapeutics Inc. announced positive initial results from the 20 mg dose cohort of the Phase 1b PIONEER trial evaluating pociredir in patients with sickle cell disease. The interim analysis showed a dose-response relationship, with a mean absolute increase in fetal hemoglobin  of 9.9% at Week 6 in the 20 mg cohort, compared to 5.6% in the 12 mg cohort. At Week 6, 58% of patients in the 20 mg cohort achieved absolute HbF levels of 20% or higher. Among patients who reached the Week 12 visit, the 20 mg cohort demonstrated a greater than 3.75-fold mean induction of HbF. Pociredir was generally well-tolerated with no treatment-related serious adverse events reported. These results were presented at the 67th American Society of Hematology Annual Meeting, and Fulcrum Therapeutics will host an investor event on December 7, 2025, to further discuss the data.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251206:nNDL2QZZPZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NDAQ","IE00BGHQF748.EUR","LU2210150020.SGD","LU2095319765.USD","IE00B64PRP62.GBP","BK4007","IE00B3QW5Z07.USD","SG9999014021.USD","SG9999014013.SGD","FULC","BK4112","BK4585","SG9999014005.SGD","BK4588","LU2210149790.SGD","IE00BKPKM429.USD","LU0314104364.USD"],"gpt_icon":0},{"id":"2589400824","title":"BioNTech Reports Gotistobart Shows Significant Survival Benefit in Phase 3 Lung Cancer Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2589400824","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589400824?lang=en_us&edition=fundamental","pubTime":"2025-12-07 04:30","pubTimestamp":1765053020,"startTime":"0","endTime":"0","summary":"BioNTech SE and OncoC4, Inc. have announced new data from the initial, non-registrational dose-finding phase of the global, randomized Phase 3 PRESERVE-003 clinical trial  for Gotistobart . Gotistobart, a selective Treg-modulator targeting CTLA-4, is being evaluated in patients with metastatic squamous non-small cell lung cancer  whose disease progressed following prior anti-PD-1 therapy and platinum-based chemotherapy. The candidate demonstrated a clinically relevant overall survival benefit compared to standard chemotherapy and exhibited a manageable safety profile. In the first part of the study, Gotistobart reduced the risk of death by more than half versus standard chemotherapy. Median overall survival for patients receiving Gotistobart was not reached after nearly 15 months of follow-up, whereas the chemotherapy group had a median overall survival of 10 months. These data were presented at the IASLC ASCO 2025 North America Conference on Lung Cancer.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251206:nNDLbFbxvC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IE00BKPKM429.USD","BK4568","BNTX","LU2095319765.USD","SG9999014005.SGD","BK4548","LU2210150020.SGD","NDAQ","BK4551","LU2210149790.SGD","BK4585","IE00BGHQF748.EUR","IE00B3QW5Z07.USD","IE00B64PRP62.GBP","BK4535","BK4588","LU0314104364.USD","BK4112","SG9999014021.USD","SG9999014013.SGD"],"gpt_icon":0},{"id":"2589765821","title":"Legend Biotech Reports CARVYKTI Achieves 50.4-Month Median PFS in Multiple Myeloma Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2589765821","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2589765821?lang=en_us&edition=fundamental","pubTime":"2025-12-07 03:00","pubTimestamp":1765047628,"startTime":"0","endTime":"0","summary":"Legend Biotech Corporation has announced new long-term clinical and translational data for its CARVYKTI  therapy from the CARTITUDE-1 and CARTITUDE-4 studies in patients with relapsed or refractory multiple myeloma. In triple-class-exposed patients who had received three prior lines of therapy, a median progression-free survival of 50.4 months was observed following a single infusion of CARVYKTI. Additionally, 80% of patients with standard-risk cytogenetics in the CARTITUDE-4 study remained progression-free and off treatment at 30 months after a single infusion. The results were presented at the American Society of Hematology  2025 annual meeting. Legend Biotech also presented first-in-human clinical data for its allogeneic CAR-T candidate LUCAR-G39D in adults with relapsed or refractory B-cell non-Hodgkin lymphoma. The study demonstrated a manageable safety profile and encouraging antitumor activity, with an overall response rate of 75% and a complete response rate of 37.5% among trea","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251206:nNDL4lzfb6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","IE00BKPKM429.USD","HK0000320223.HKD","HK0000306685.HKD","LU0314104364.USD","BK4139","HK0000306701.USD","IE00BGHQF748.EUR","BK4505","SG9999014013.SGD","BK1141","LEGN","01548","BK4112","BK1583","SG9999014021.USD","SG9999014005.SGD","LU2210149790.SGD","BK4588","HK0000320264.USD","LU2095319765.USD","BK1576","LU2210150020.SGD","IE00B3QW5Z07.USD","NDAQ","IE00B64PRP62.GBP"],"gpt_icon":0}],"pageSize":4,"totalPage":263,"pageCount":1,"totalSize":1052,"code":"91000000","status":"200"}],"@#url:\"https://hq.skytigris.cn/market/plate/belongs/NDAQ\",params:#limit:6,delay:false,,,undefined,":[{"market":"US","name":"ETF & Stock Investment","bkCode":"BK4585","id":"package_us_concept_etf&gpdt","changeRate":0.002133},{"market":"US","name":"Fractional Shares","bkCode":"BK4588","id":"package_us_concept_sg","changeRate":0.00215}]}}